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Review

Tuberculosis: vaccines in the pipeline

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Pages 635-650 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Sergio Rosales-Mendoza, Regina Ríos-Huerta & Carlos Angulo. (2015) An overview of tuberculosis plant-derived vaccines. Expert Review of Vaccines 14:6, pages 877-889.
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Marisol Ocampo, Manuel A. Patarroyo, Magnolia Vanegas, Martha P. Alba & Manuel E. Patarroyo. (2014) Functional, biochemical and 3D studies of Mycobacterium tuberculosis protein peptides for an effective anti-tuberculosis vaccine. Critical Reviews in Microbiology 40:2, pages 117-145.
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Carlos R. Zárate-Bladés, Rodrigo F. Rodrigues, Patricia R. M. Souza, Wendy M. Rios, Luana S. Soares, Rogério S. Rosada, Izaíra T. Brandão, Ana Paula Masson, Elaine M. Floriano, Simone G. Ramos & Celio L. Silva. (2013) Evaluation of the overall IFN-γ and IL-17 pro-inflammatory responses after DNA therapy of tuberculosis. Human Vaccines & Immunotherapeutics 9:5, pages 1093-1103.
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Amando Zuniga, Mathias Liniger, Teldja Neige Azzouz Morin, René R. Marty, Marian Wiegand, Orhan Ilter, Sara Weibel, Martin A. Billeter, Marlyse C. Knuchel & Hussein Y. Naim. (2013) Sequence and immunogenicity of a clinically approved novel measles virus vaccine vector. Human Vaccines & Immunotherapeutics 9:3, pages 607-613.
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David N McMurray & Lan H Ly. (2009) TB vaccines: the paradigms they are a-shifting. Expert Review of Vaccines 8:12, pages 1615-1618.
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Zhou Xing. (2009) Importance of T-cell location rekindled: implication for tuberculosis vaccination strategies. Expert Review of Vaccines 8:11, pages 1465-1468.
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Abu Salim Mustafa. (2009) Vaccine potential of Mycobacterium tuberculosis-specific genomic regions: in vitro studies in humans. Expert Review of Vaccines 8:10, pages 1309-1312.
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Articles from other publishers (33)

Khethiwe Nomcebo Bhengu, Pragalathan Naidoo, Ravesh Singh, Miranda N. Mpaka-Mbatha, Nomzamo Nembe, Zamathombeni Duma, Roxanne Pillay & Zilungile L. Mkhize-Kwitshana. (2022) Immunological Interactions between Intestinal Helminth Infections and Tuberculosis. Diagnostics 12:11, pages 2676.
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Puja S. Nagpal, Ashwani Kesarwani, Parul Sahu & Pramod Upadhyay. (2019) Aerosol immunization by alginate coated mycobacterium (BCG/MIP) particles provide enhanced immune response and protective efficacy than aerosol of plain mycobacterium against M.tb. H37Rv infection in mice. BMC Infectious Diseases 19:1.
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Дэвид Н. МакМаррей. (2019) ВКЛАД МОДЕЛИ ТУБЕРКУЛЕЗНОЙ ИНФЕКЦИИ НА МОРСКИХ СВИНКАХ В ПОНИМАНИЕ ПАТОГЕНЕЗА ИНФЕКЦИИ, "Вестник Центрального научно-исследовательского института туберкулеза". Вестник ЦНИИТ:2, pages 7-15.
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Mohd Saqib, Rahul Khatri, Bindu Singh, Ananya Gupta, Arvind Kumar & Sangeeta Bhaskar. (2016) Mycobacterium indicus pranii as a booster vaccine enhances BCG induced immunity and confers higher protection in animal models of tuberculosis. Tuberculosis 101, pages 164-173.
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David N. McMurray. 2016. Drug Delivery Systems for Tuberculosis Prevention and Treatment. Drug Delivery Systems for Tuberculosis Prevention and Treatment 48 65 .
Aliabbas A. Husain, Hatim F. Daginawala, Lokendra Singh & Rajpal S. Kashyap. (2016) Current perspective in tuberculosis vaccine development for high TB endemic regions. Tuberculosis 98, pages 149-158.
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Xun Liu, Zejiao Da, Yue Wang, Hongxia Niu, Ruiying Li, Hongjuan Yu, Shanshan He, Ming Guo, Yong Wang, Yanping Luo, Xingming Ma & Bingdong Zhu. (2016) A novel liposome adjuvant DPC mediates Mycobacterium tuberculosis subunit vaccine well to induce cell-mediated immunity and high protective efficacy in mice. Vaccine 34:11, pages 1370-1378.
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K F Siddiqui, M Amir, N Khan, G Rama Krishna, J A Sheikh, K Rajagopal & J N Agrewala. (2015) Prime-boost vaccination strategy with bacillus Calmette–Guérin (BCG) and liposomized alpha-crystalline protein 1 reinvigorates BCG potency. Clinical and Experimental Immunology 181:2, pages 286-296.
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Bhagwati Khatri, Adam Whelan, Derek Clifford, Agnese Petrera, Peter Sander & H. Martin Vordermeier. (2014) BCG Δzmp1 vaccine induces enhanced antigen specific immune responses in cattle. Vaccine 32:7, pages 779-784.
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Robin Wood. 2014. Manson's Tropical Infectious Diseases. Manson's Tropical Infectious Diseases 79 96.e6 .
Wenqing Ai, Yan Yue, Sidong Xiong & Wei Xu. (2013) Enhanced protection against pulmonary mycobacterial challenge by chitosan‐formulated polyepitope gene vaccine is associated with increased pulmonary secretory IgA and gamma‐interferon + T cell responses . Microbiology and Immunology 57:3, pages 224-235.
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Carly N. Horvath & Zhou Xing. 2013. The New Paradigm of Immunity to Tuberculosis. The New Paradigm of Immunity to Tuberculosis 267 278 .
W. Ray Waters, Mitchell V. Palmer, Bryce M. Buddle & H. Martin Vordermeier. (2012) Bovine tuberculosis vaccine research: Historical perspectives and recent advances. Vaccine 30:16, pages 2611-2622.
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S. N. M. Hanif, R. Al‐Attiyah & A. S. Mustafa. (2011) Cellular Immune Responses in Mice Induced by M. tuberculosis PE35 ‐DNA Vaccine Construct . Scandinavian Journal of Immunology 74:6, pages 554-560.
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Bappaditya Dey, Ruchi Jain, Umesh D. Gupta, V. M. Katoch, V. D. Ramanathan & Anil K. Tyagi. (2011) A Booster Vaccine Expressing a Latency-Associated Antigen Augments BCG Induced Immunity and Confers Enhanced Protection against Tuberculosis. PLoS ONE 6:8, pages e23360.
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W. Ray Waters, Mitchell V. Palmer, Tyler C. Thacker, William C. Davis, Srinand Sreevatsan, Paul Coussens, Kieran G. Meade, Jayne C. Hope & D. Mark Estes. (2011) Tuberculosis Immunity: Opportunities from Studies with Cattle. Clinical and Developmental Immunology 2011, pages 1-11.
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G. G. Guerrero & C. Locht. (2011) Recombinant HBHA Boosting Effect on BCG-Induced Immunity against Mycobacterium tuberculosis Infection . Clinical and Developmental Immunology 2011, pages 1-8.
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H. Zhang, P. Peng, S. Miao, Y. Zhao, F. Mao, L. Wang, Y. Bai, Z. Xu, S. Wei & C. Shi. (2010) Recombinant Mycobacterium smegmatis Expressing an ESAT6-CFP10 Fusion Protein Induces Anti-Mycobacterial Immune Responses and Protects Against Mycobacterium tuberculosis Challenge in Mice. Scandinavian Journal of Immunology 72:4, pages 349-357.
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Simon O. Clark, Dominic L.F. Kelly, Edgar Badell, Luiz Roberto Castello-Branco, Frank Aldwell, Nathalie Winter, David J.M. Lewis & Philip D. Marsh. (2010) Oral delivery of BCG Moreau Rio de Janeiro gives equivalent protection against tuberculosis but with reduced pathology compared to parenteral BCG Danish vaccination. Vaccine 28:43, pages 7109-7116.
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Pui-Hang Tam & Todd L. Lowary. 2010. Carbohydrate Chemistry. Carbohydrate Chemistry 38 63 .
Christine T. McFarland, Lan Ly, Amminikutty Jeevan, Toshiko Yamamoto, Bradley Weeks, Angelo Izzo & David McMurray. (2010) BCG vaccination in the cotton rat (Sigmodon hispidus) infected by the pulmonary route with virulent Mycobacterium tuberculosis. Tuberculosis 90:4, pages 262-267.
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Mangalakumari Jeyanathan, Armando Heriazon & Zhou Xing. (2010) Airway luminal T cells: A newcomer on the stage of TB vaccination strategies. Trends in Immunology 31:7, pages 247-252.
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C. A. Molina-Torres, J. Castro-Garza, J. Ocampo-Candiani, M. Monot, S. T. Cole & L. Vera-Cabrera. (2010) Effect of serial subculturing on the genetic composition and cytotoxicactivity of Mycobacterium tuberculosis. Journal of Medical Microbiology 59:4, pages 384-391.
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Doreen Manuela Floss, Michael Mockey, Galliano Zanello, Damien Brosson, Marie Diogon, Roger Frutos, Timothée Bruel, Valérie Rodrigues, Edwin Garzon, Claire Chevaleyre, Mustapha Berri, Henri Salmon, Udo Conrad & Laurence Dedieu. (2010) Expression and Immunogenicity of the Mycobacterial Ag85B/ESAT-6 Antigens Produced in Transgenic Plants by Elastin-Like Peptide Fusion Strategy. Journal of Biomedicine and Biotechnology 2010, pages 1-14.
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Peter J. White & Geoff P. Garnett. 2010. Modelling Parasite Transmission and Control. Modelling Parasite Transmission and Control 127 140 .
Philippe Glaziou, Katherine Floyd & Mario Raviglione. (2009) Global Burden and Epidemiology of Tuberculosis. Clinics in Chest Medicine 30:4, pages 621-636.
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Paul-Henri Lambert, Tony Hawkridge & Willem A. Hanekom. (2009) New Vaccines Against Tuberculosis. Clinics in Chest Medicine 30:4, pages 811-826.
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H. Martin Vordermeier, Gillian S. Dean, Ida Rosenkrands, Else M. Agger, Peter Andersen, Daryan A. Kaveh, R. Glyn Hewinson & Philip J. Hogarth. (2009) Adjuvants Induce Distinct Immunological Phenotypes in a Bovine Tuberculosis Vaccine Model. Clinical and Vaccine Immunology 16:10, pages 1443-1448.
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S.-A. Hwang & J. K. Actor. (2009) Lactoferrin modulation of BCG-infected dendritic cell functions. International Immunology 21:10, pages 1185-1197.
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Yamilé López, Daniel Yero, Gustavo Falero-Diaz, Nesty Olivares, María E. Sarmiento, Sergio Sifontes, Rosa L. Solis, Jorge A. Barrios, Diana Aguilar, Rogelio Hernández-Pando & Armando Acosta. (2009) Induction of a protective response with an IgA monoclonal antibody against Mycobacterium tuberculosis 16kDa protein in a model of progressive pulmonary infection. International Journal of Medical Microbiology 299:6, pages 447-452.
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JES DIETRICH & T. MARK DOHERTY. (2009) Interaction of Mycobacterium tuberculosis with the host: consequences for vaccine development . APMIS 117:5-6, pages 440-457.
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Alimuddin Zumla, Peter Mwaba, Jim Huggett, Nathan Kapata, Duncan Chanda & John Grange. (2009) Reflections on the white plague. The Lancet Infectious Diseases 9:3, pages 197-202.
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Ruchi Jain, Bappaditya Dey, Neeraj Dhar, Vivek Rao, Ramandeep Singh, Umesh D. Gupta, V. M. Katoch, V. D. Ramanathan & Anil K. Tyagi. (2008) Enhanced and Enduring Protection against Tuberculosis by Recombinant BCG-Ag85C and Its Association with Modulation of Cytokine Profile in Lung. PLoS ONE 3:12, pages e3869.
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