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Drug profiles

An evaluation of alirocumab for the treatment of hypercholesterolemia

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Dragan Kalinić, Ranko Škrbić, Duško Vulić, Svjetlana Stoisavljević-Šatara, Nataša Stojaković, Miloš P Stojiljković, Vanda Marković-Peković, Ana Golić Jelić, Nataša Pilipović-Broćeta & Nevena Divac. (2023) Eleven-Year Trends in Lipid-Modifying Medicines Utilisation and Expenditure in a Low-Income Country: A Study from the Republic of Srpska, Bosnia and Herzegovina. ClinicoEconomics and Outcomes Research 15, pages 513-523.
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Najmeh Ahangari, Majid Ghayour Mobarhan, Amirhossein Sahebkar & Alireza Pasdar. (2018) Molecular aspects of hypercholesterolemia treatment: current perspectives and hopes. Annals of Medicine 50:4, pages 303-311.
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Michel Farnier. (2017) Alirocumab for the treatment of hyperlipidemia in high-risk patients: an updated review. Expert Review of Cardiovascular Therapy 15:12, pages 923-932.
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Mingqi Ouyang, Chenyu Li, Die Hu, Daoquan Peng & Bilian Yu. (2022) Mechanisms of unusual response to lipid-lowering therapy: PCSK9 inhibition. Clinica Chimica Acta.
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Chayakrit Krittanawong, Muzamil Khawaja, Robert S Rosenson, Christopher I. Amos, Vijay Nambi, Carl J Lavie & Salim S. Virani. (2022) Association of PCSK9 Variants With the Risk of Atherosclerotic Cardiovascular Disease and Variable Responses to PCSK9 Inhibitor Therapy. Current Problems in Cardiology 47:7, pages 101043.
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Victoria A. Korneva, Tatjana Yurjevna Kuznetsova & Ulrich Julius. (2021) Modern Approaches to Lower Lipoprotein(a) Concentrations and Consequences for Cardiovascular Diseases. Biomedicines 9:9, pages 1271.
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M. Farnier. (2021) Nuevos hipolipidemiantes. EMC - Tratado de Medicina.
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Lili Wang, Camilo Breton, Claude C. Warzecha, Peter Bell, Hanying Yan, Zhenning He, John White, Yanqing Zhu, Mingyao Li, Elizabeth L. Buza, Derek Jantz & James M. Wilson. (2021) Long-term stable reduction of low-density lipoprotein in nonhuman primates following in vivo genome editing of PCSK9. Molecular Therapy 29:6, pages 2019-2029.
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Donald J. AbrahamScott D. Edmondson, Duane A. Burnett & Harry R. DavisJrJr. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 36 .
Bruce A. Warden, Sergio Fazio & Michael D. Shapiro. (2020) The PCSK9 revolution: Current status, controversies, and future directions. Trends in Cardiovascular Medicine 30:3, pages 179-185.
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Bruce A. Warden, Joshua R. Miles, Carlota Oleaga, Om P. Ganda, P. Barton Duell, Jonathan Q. Purnell, Michael D. Shapiro & Sergio Fazio. (2020) Unusual responses to PCSK9 inhibitors in a clinical cohort utilizing a structured follow-up protocol. American Journal of Preventive Cardiology 1, pages 100012.
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C Macchi, M Banach, A Corsini, CR Sirtori, N Ferri & M Ruscica. (2019) Changes in circulating pro-protein convertase subtilisin/kexin type 9 levels – experimental and clinical approaches with lipid-lowering agents. European Journal of Preventive Cardiology 26:9, pages 930-949.
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Pierre Sabouret, Michel Farnier & Etienne Puymirat. (2019) Inhibiteurs de PCSK9 : quelle place dans la prise en charge actuelle des dyslipidémies ?. La Presse Médicale 48:3, pages 227-237.
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Michel Farnier, G. Kees Hovingh, Gisle Langslet, Robert Dufour, Marie T. Baccara-Dinet, Chantal Din-Bell, Garen Manvelian & John R. Guyton. (2018) Long-term safety and efficacy of alirocumab in patients with heterozygous familial hypercholesterolemia: An open-label extension of the ODYSSEY program. Atherosclerosis 278, pages 307-314.
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Amy C. BurkeJacqueline S. DronRobert A. Hegele & Murray W. Huff. (2017) PCSK9: Regulation and Target for Drug Development for Dyslipidemia. Annual Review of Pharmacology and Toxicology 57:1, pages 223-244.
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Michel Farnier. (2016) Proprotein convertase subtilisin kexin type 9 inhibitors: update from clinical trials to real-world experience. Current Opinion in Lipidology 27:6, pages 597-604.
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Michel Farnier. (2016) Future Lipid-Altering Therapeutic Options Targeting Residual Cardiovascular Risk. Current Cardiology Reports 18:7.
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Nabil G. Seidah. (2016) New developments in proprotein convertase subtilisin–kexin 9ʼs biology and clinical implications. Current Opinion in Lipidology 27:3, pages 274-281.
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G. Klose. (2016) Einführung der PCSK9-InhibitorenIntroduction of PCSK9 inhibitors. Herz 41:4, pages 307-312.
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