128
Views
17
CrossRef citations to date
0
Altmetric
Review

Targeting signaling pathways with small molecules to treat autoimmune disorders

&
Pages 93-112 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Andrea Chiricozzi, Rosita Saraceno, Lucia Novelli, Monika Fida, Francesco Caso, Raffaele Scarpa, Luisa Costa, Roberto Perricone, Marco Romanelli, Sergio Chimenti & Maria Sole Chimenti. (2016) Small molecules and antibodies for the treatment of psoriasis: a patent review (2010–2015). Expert Opinion on Therapeutic Patents 26:7, pages 757-766.
Read now
Andrea Chiricozzi, Dante Caposiena, Virginia Garofalo, Maria Vittoria Cannizzaro, Sergio Chimenti & Rosita Saraceno. (2016) A new therapeutic for the treatment of moderate-to-severe plaque psoriasis: apremilast. Expert Review of Clinical Immunology 12:3, pages 237-249.
Read now
Maria Sole Chimenti, Talia Gramiccia, Rosita Saraceno, Luca Bianchi, Virginia Garofalo, Oreste Buonomo, Roberto Perricone, Sergio Chimenti & Andrea Chiricozzi. (2015) Apremilast for the treatment of psoriasis. Expert Opinion on Pharmacotherapy 16:13, pages 2083-2094.
Read now
Andrea Chiricozzi, Sara Faleri, Rosita Saraceno, Luca Bianchi, Oreste Buonomo, Sergio Chimenti & Maria Sole Chimenti. (2015) Tofacitinib for the treatment of moderate-to-severe psoriasis. Expert Review of Clinical Immunology 11:4, pages 443-455.
Read now

Articles from other publishers (13)

Madison McGraw, David Miller, Sorena Lo & Nirmala Parajuli. (2023) Cold Storage Followed by Transplantation Induces Interferon-Gamma and STAT-1 in Kidney Grafts. International Journal of Molecular Sciences 24:6, pages 5468.
Crossref
Rui Han, Tian Yuan, Zhi Yang, Qiang Zhang, Wei-Wei Wang, Li-Bin Lin, Ming-Qiang Zhu & Jin-Ming Gao. (2021) Ulmoidol, an unusual nortriterpenoid from Eucommia ulmoides Oliv. Leaves prevents neuroinflammation by targeting the PU.1 transcriptional signaling pathway. Bioorganic Chemistry 116, pages 105345.
Crossref
Hsin-Ning Chang, Yuan-Chieh Yeh, Ho-Yen Chueh & Jong-Hwei S. Pang. (2019) The anti-angiogenic effect of tryptanthrin is mediated by the inhibition of apelin promoter activity and shortened mRNA half-life in human vascular endothelial cells. Phytomedicine 58, pages 152879.
Crossref
K. Clarysse, C.M. Pfaff, Y. Marquardt, L. Huth, I. Kortekaas Krohn, D. Kluwig, B. Lüscher, J. Gutermuth & J. Baron. (2019) JAK1/3 inhibition preserves epidermal morphology in full-thickness 3D skin models of atopic dermatitis and psoriasis. Journal of the European Academy of Dermatology and Venereology 33:2, pages 367-375.
Crossref
Ashwaq A Abdullah, Rasedee Abdullah, Zeenathul A Nazariah, Krishnan N Balakrishnan, Faez Firdaus J Abdullah, Jamilu A Bala & Mohd-Azmi Mohd-Lila. (2018) Cyclophilin A as a target in the treatment of cytomegalovirus infections. Antiviral Chemistry and Chemotherapy 26, pages 204020661881141.
Crossref
Yongwei Li, Zhengfei Shan, Chu Liu, Diandong Yang, Jitao Wu, Changping Men & Yankai Xu. (2017) MicroRNA-294 promotes cellular proliferation and motility through the PI3K/AKT and JAK/STAT pathways by upregulation of NRAS in bladder cancer. Biochemistry (Moscow) 82:4, pages 474-482.
Crossref
Allison B. Webber & Flavio Vincenti. (2016) An Update on Calcineurin Inhibitor–Free Regimens. Transplantation 100:4, pages 836-843.
Crossref
Ross D. O'Shea, Chew L. Lau, Natasha Zulaziz, Francesca L. Maclean, David R. Nisbet, Malcolm K. Horne & Philip M. Beart. (2015) Transcriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis. Frontiers in Neuroscience 9.
Crossref
Allison B. Webber & Flavio Vincenti. 2014. Textbook of Organ Transplantation. Textbook of Organ Transplantation 239 249 .
Piotr Przanowski, Michal Dabrowski, Aleksandra Ellert-Miklaszewska, Michal Kloss, Jakub Mieczkowski, Beata Kaza, Anna Ronowicz, Feng Hu, Arkadiusz Piotrowski, Helmut Kettenmann, Jan Komorowski & Bozena Kaminska. (2013) The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. Journal of Molecular Medicine 92:3, pages 239-254.
Crossref
Edward Keystone & Marc D. Cohen. (2013) Cell-Signaling Therapy in Rheumatoid Arthritis. Current Rheumatology Reports 15:10.
Crossref
Malgorzata Zawadzka, Michal Dabrowski, Agata Gozdz, Barbara Szadujkis, Marcin Sliwa, Maciej Lipko & Bozena Kaminska. (2012) Early steps of microglial activation are directly affected by neuroprotectant FK506 in both in vitro inflammation and in rat model of stroke. Journal of Molecular Medicine 90:12, pages 1459-1471.
Crossref
Bozena Kaminska, Agata Gozdz, Malgorzata Zawadzka, Aleksandra Ellert-Miklaszewska & Maciej Lipko. (2009) MAPK Signal Transduction Underlying Brain Inflammation and Gliosis as Therapeutic Target. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology 292:12, pages 1902-1913.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.