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Expert Review of Clinical Immunology Volume 7, 2011 - Issue 4
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Review

CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases

Jocea MR Michels-van Amelsfort Department of Rheumatology & Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands; Department of Rheumatology & Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands
,
Gina J Walter Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Disease, King’s College London, UK; Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Disease, King’s College London, UK
&
Leonie S Taams Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Disease, King’s College London, UK; Faculty of Translational Medicine, NIHR Comprehensive Biomedical Research Centre at Guy’s & St Thomas’ NHS Foundation Trust in partnership with King’s College London and King’s College Hospital NHS Foundation Trust, UK;[email protected]
Pages 499-514 | Published online: 10 Jan 2014

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Jagadeesh Bayry & Timothy R Radstake. (2013) Immune-mediated inflammatory diseases: progress in molecular pathogenesis and therapeutic strategies. Expert Review of Clinical Immunology 9:4, pages 297-299.
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Timothy RDJ Radstake. (2011) Novel insights in the pathogenesis of systemic sclerosis. Expert Review of Clinical Immunology 7:4, pages 389-390.
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Articles from other publishers (21)

Jiao Luo, Dongdong Li, Lili Jiang, Chunhua Shi & Lihua Duan. (2023) Identification of Tregs-Related Genes with Molecular Patterns in Patients with Systemic Sclerosis Related to ILD. Biomolecules 13:3, pages 535.
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Cuiling Mo, Zhuotong Zeng, Qiancheng Deng, Yan Ding & Rong Xiao. (2018) Imbalance between T helper 17 and regulatory T cell subsets plays a significant role in the pathogenesis of systemic sclerosis. Biomedicine & Pharmacotherapy 108, pages 177-183.
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Essam Mohammed Ahmed Janahi, Shukla Das, Sambit Nath Bhattacharya, Shafiul Haque, Naseem Akhter, Arshad Jawed, Mohd Wahid, Raju Kumar Mandal, Mohtashim Lohani, Mohammed Yahya Areeshi, Vishnampettai G. Ramachandran, Shaia Almalki & Sajad Ahmad Dar. (2018) Cytomegalovirus aggravates the autoimmune phenomenon in systemic autoimmune diseases. Microbial Pathogenesis 120, pages 132-139.
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Gleb Slobodin & Doron Rimar. (2016) Regulatory T Cells in Systemic Sclerosis: a Comprehensive Review. Clinical Reviews in Allergy & Immunology 52:2, pages 194-201.
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Paulina García-González, Gabriela Ubilla-Olguín, Diego Catalán, Katina Schinnerling & Juan Carlos Aguillón. (2016) Tolerogenic dendritic cells for reprogramming of lymphocyte responses in autoimmune diseases. Autoimmunity Reviews 15:11, pages 1071-1080.
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Kenneth Michael Pollard. (2016) Silica, Silicosis, and Autoimmunity. Frontiers in Immunology 7.
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Gina J. Walter, Veerle Fleskens, Klaus S. Frederiksen, Megha Rajasekhar, Bina Menon, Jens G. Gerwien, Hayley G. Evans & Leonie S. Taams. (2016) Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127 low Treg Cells in Patients With Chronic Rheumatoid Arthritis . Arthritis & Rheumatology 68:1, pages 103-116.
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Doron Rimar, Yuval Nov, Itzhak Rosner, Gleb Slobodin, Michael Rozenbaum, Katy Halasz, Tharwat Haj, Nizar Jiries, Lisa Kaly, Nina Boulman & Zahava Vadasz. (2015) Semaphorin 3A: an immunoregulator in systemic sclerosis. Rheumatology International 35:10, pages 1625-1630.
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M Müller, J Herrath & V Malmström. (2015) IL-1R1 is expressed on both Helios+ and Helios−FoxP3+CD4+ T cells in the rheumatic joint. Clinical and Experimental Immunology 182:1, pages 90-100.
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Takashi Ishida, Tatsuro Jo, Shigeki Takemoto, Hitoshi Suzushima, Kimiharu Uozumi, Kazuhito Yamamoto, Naokuni Uike, Yoshio Saburi, Kisato Nosaka, Atae Utsunomiya, Kensei Tobinai, Hiroshi Fujiwara, Kenji Ishitsuka, Shinichiro Yoshida, Naoya Taira, Yukiyoshi Moriuchi, Kazunori Imada, Toshihiro Miyamoto, Shiro Akinaga, Masao Tomonaga & Ryuzo Ueda. (2015) Dose‐intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T‐cell leukaemia‐lymphoma: a randomized phase II study . British Journal of Haematology 169:5, pages 672-682.
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J.Y. Humrich, T. Kamradt & G. Riemekasten. (2015) Regulatorische T-Zellen und rheumatische ErkrankungenRegulatory T cells and rheumatic diseases. Zeitschrift für Rheumatologie 74:1, pages 26-32.
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Chandrashekhar R. Gandhi. 2015. Stellate Cells in Health and Disease. Stellate Cells in Health and Disease 227 250 .
Zhengyu Zhu, Wei You, ZhaoHong Xie, Ping Wang, Zhen Liu, Cunfu Wang & JianZhong Bi. (2014) Mycophenolate mofetil improves neurological function and alters blood T-lymphocyte subsets in rats with experimental autoimmune encephalomyelitis. Journal of International Medical Research 42:2, pages 530-541.
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Naoki Murao, Ken-ichiro Seino, Toshihiko Hayashi, Masaki Ikeda, Emi Funayama, Hiroshi Furukawa, Yuhei Yamamoto & Akihiko Oyama. (2014) Treg-enriched CD4+ T cells attenuate collagen synthesis in keloid fibroblasts. Experimental Dermatology 23:4, pages 266-271.
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Amit Golding, Sarfaraz Hasni, Gabor Illei & Ethan M. Shevach. (2013) The Percentage of FoxP3+Helios+ Treg Cells Correlates Positively With Disease Activity in Systemic Lupus Erythematosus. Arthritis & Rheumatism 65:11, pages 2898-2906.
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Behdad Afzali, Peter J. Mitchell, Francis C. Edozie, Giovanni A.M. Povoleri, Sophie E. Dowson, Laura Demandt, Gina Walter, James B. Canavan, Cristiano Scotta, Bina Menon, Prabhjoat S. Chana, Wafa Khamri, Shahram Y. Kordasti, Susanne Heck, Bodo Grimbacher, Timothy Tree, Andrew P. Cope, Leonie S. Taams, Robert I. Lechler, Susan John & Giovanna Lombardi. (2013) CD 161 expression characterizes a subpopulation of human regulatory T cells that produces IL ‐17 in a STAT 3‐dependent manner . European Journal of Immunology 43:8, pages 2043-2054.
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Takashi Ishida, Asahi Ito, Fumihiko Sato, Shigeru Kusumoto, Shinsuke Iida, Hiroshi Inagaki, Akimichi Morita, Shiro Akinaga & Ryuzo Ueda. (2013) Stevens–Johnson S yndrome associated with mogamulizumab treatment of adult T ‐cell leukemia / lymphoma . Cancer Science 104:5, pages 647-650.
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Gina J. Walter, Hayley G. Evans, Bina Menon, Nicola J. Gullick, Bruce W. Kirkham, Andrew P. Cope, Frédéric Geissmann & Leonie S. Taams. (2013) Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127 low regulatory T cells . Arthritis & Rheumatism 65:3, pages 627-638.
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Paola Cordiali-Fei, Anna Mussi, Giovanna D'Agosto, Elisabetta Trento, Valentina Bordignon, Silvana Trincone, Antonella Vento, Isabella Sperduti, Antonio Cristaudo & Fabrizio Ensoli. (2013) Assessment of T Regulatory Cells and Expanded Profiling of Autoantibodies May Offer Novel Biomarkers for the Clinical Management of Systemic Sclerosis and Undifferentiated Connective Tissue Disease. Clinical and Developmental Immunology 2013, pages 1-7.
Crossref
Zhuochun Huang, Bin Yang, Yunying Shi, Bei Cai, Yi Li, Weihua Feng, Yang Fu, Limei Luo & Lanlan Wang. (2012) Anti-TNF-α therapy improves Treg and suppresses Teff in patients with rheumatoid arthritis. Cellular Immunology 279:1, pages 25-29.
Crossref
Wan Lei & Liu Jian. (2012) Changes of CD4 + CD25 + Regulatory T Cells, FoxP3 in Adjuvant Arthritis Rats with Damage of Pulmonary Function and Effects of Tripterygium Glycosides Tablet . International Journal of Rheumatology 2012, pages 1-7.
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