Citations (43)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
Biljana Škorić, Miloš Kuzmanović, Marija Jovanović, Branislava Miljković, Dragan Micić, Milena Jović, Ankica Jovanović & Katarina Vučićević. (2023) Methotrexate concentrations and associated variability factors in high dose therapy of children with acute lymphoblastic leukemia and non-Hodgkin lymphoma. Pediatric Hematology and Oncology 40:5, pages 446-457.
Read now
Read now
Fatemeh Jafari, Omid Arasteh, Hesamoddin Hosseinjani, Abolghasem Allahyari, Sajad Ataei Azimi & Vahid Reza Askari. (2023) A critical review of methotrexate clinical interactions: role of transporters. Expert Opinion on Drug Metabolism & Toxicology 19:2, pages 91-107.
Read now
Read now
Joel Wight, Matthew Ku, Melissa Garwood, Duncan Carradice, Masa Lasica, Louise Keamy, Eliza A. Hawkes & Andrew Grigg. (2022) Toxicity associated with high-dose intravenous methotrexate for hematological malignancies. Leukemia & Lymphoma 63:10, pages 2375-2382.
Read now
Read now
Ryo Inose, Katsuyuki Takahashi, Satoru Nanno, Masayuki Hino & Katsuya Nagayama. (2019) Calcium Channel Blockers Possibly Delay the Elimination of Plasma Methotrexate in Patients Receiving High-Dose Methotrexate Therapy. Journal of Chemotherapy 31:1, pages 30-34.
Read now
Read now
Tiene Bauters, Tim Lammens, Pauline Belin, Yves Benoit, Hugo Robays & Barbara de Moerloose. (2013) Delayed elimination of methotrexate by cola beverages in a pediatric acute lymphoblastic leukemia population. Leukemia & Lymphoma 54:5, pages 1094-1096.
Read now
Read now
Jacalyn M Green. (2012) Glucarpidase to combat toxic levels of methotrexate in patients. Therapeutics and Clinical Risk Management 8, pages 403-413.
Read now
Read now
Articles from other publishers (37)
Chang Jian, Siqi Chen, Zhuangcheng Wang, Yang Zhou, Yang Zhang, Ziyu Li, Jie Jian, Tingting Wang, Tianyu Xiang, Xiao Wang, Yuntao Jia, Huilai Wang & Jun Gong. (2023) Predicting delayed methotrexate elimination in pediatric acute lymphoblastic leukemia patients: an innovative web-based machine learning tool developed through a multicenter, retrospective analysis. BMC Medical Informatics and Decision Making 23:1.
Crossref
Crossref
Sheng‐Fan Wang, Kuan‐Wei Huang, Yueh‐Ching Chou, Hsin‐Chen Lee, Po‐Kuei Wu, Wei‐Ming Chen, Giun‐Yi Hung & Yuh‐Lih Chang. (2023)
Effect of c
o‐medications
and potential risk factors of
high‐dose methotrexate‐mediated
acute hepatotoxicity in patients with osteosarcoma
. Cancer Medicine 12:11, pages 12354-12364.
Crossref
Crossref
Shaimaa Barakat, Hala Assem, Mostafa Salama, Neveen Mikhael & Yasmine El Chazli. (2022) Is hypoalbuminemia a risk factor for high-dose methotrexate toxicity in children with acute lymphoblastic leukemia?. Journal of the Egyptian National Cancer Institute 34:1.
Crossref
Crossref
Wanwen Weng, Jiawei Hong, Kwabena G. Owusu-Ansah, Bingjie Chen, Shusen Zheng & Donghai Jiang. (2022) Pralatrexate mediates effective killing of gemcitabine-resistant pancreatic cancer: role of mTOR/4E-BP1 signal pathway. Heliyon 8:12, pages e12064.
Crossref
Crossref
Qi-Hai Wang, Shu Pan, Kui Yang, Yi-Jin Wu, Xiu-Ping Cheng, Opeyemi Joshua Olatunji, Qingcheng Mao & Jian Zuo. (2022) Glycolysis aggravates methotrexate toxicity by fueling RFC1-controlled intestinal absorption in rheumatic rats. Biomedicine & Pharmacotherapy 150, pages 113067.
Crossref
Crossref
Junjun Mao, Qing Li, Pei Li, Weiwei Qin, Bobin Chen & Mingkang Zhong. (2022) Evaluation and Application of Population Pharmacokinetic Models for Identifying Delayed Methotrexate Elimination in Patients With Primary Central Nervous System Lymphoma. Frontiers in Pharmacology 13.
Crossref
Crossref
Seema Kohli & Lavakesh Kumar Omray. 2022. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology
165
179
.
Omid Vakili, Seyyed Hossein Khatami, Amir Maleksabet, Ahmad Movahedpour, Saeed Ebrahimi Fana, Rasoul Sadegh, Amir Hossein Salmanzadeh, Hadi Razeghifam, Sajjad Nourdideh, Sadra Samavarchi Tehrani & Mortaza Taheri-Anganeh. (2021) Finding Appropriate Signal Peptides for Secretory Production of Recombinant Glucarpidase: An In Silico Method. Recent Patents on Biotechnology 15:4, pages 302-315.
Crossref
Crossref
Min Zhan, Zebin Chen, Changcai Ding, Qiang Qu, Guoqiang Wang, Sixi Liu & Feiqiu Wen. (2021) Risk prediction for delayed clearance of high-dose methotrexate in pediatric hematological malignancies by machine learning. International Journal of Hematology 114:4, pages 483-493.
Crossref
Crossref
Araújo Filho W. D, Chaves Antônio A. G. S, Dos Santos F. F.A. F. Santos Junior. (2021) IMPROVEMENT OF THE MICROFLUIDIC DEVICE FOR THE GENERATION OF MONODISPERSE MICROBUBBLES AS DRUG TRANSPORT SYSTEMS. International Journal of Research -GRANTHAALAYAH 9:8, pages 109-124.
Crossref
Crossref
Xuan Gao, Xiao-Wen Qian, Xiao-Hua Zhu, Yi Yu, Hui Miao, Jian-Hua Meng, Jun-Ye Jiang, Hong-Sheng Wang & Xiao-Wen Zhai. (2021) Population Pharmacokinetics of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia. Frontiers in Pharmacology 12.
Crossref
Crossref
Junqing He, Junyan Wang, Min Zhang & Guoyue Shi. (2021) Selection of a Structure-Switching Aptamer for the Specific Methotrexate Detection. ACS Sensors 6:6, pages 2436-2441.
Crossref
Crossref
Catherine E. DeFino, Jason N. Barreto, Amanda G. Pawlenty, Michael W. Ruff, Ivan D. Carabenciov, Kristin C. Mara & Carrie A. Thompson. (2021) Lack of drug interaction between levetiracetam and high‐dose methotrexate in patients with lymphoma. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 41:5, pages 430-439.
Crossref
Crossref
Bushra Salman & Murtadha Al-Khabori. (2020) Applications and challenges in therapeutic drug monitoring of cancer treatment: A review. Journal of Oncology Pharmacy Practice 27:3, pages 693-701.
Crossref
Crossref
Winfried Alsdorf, Martin Sökler, Ulrich Jaehde & Carsten Bokemeyer. 2020. Kompendium Internistische Onkologie. Kompendium Internistische Onkologie
1
4
.
Uvette Lou, Jamie Kwok, Thu Anne Nguyen, Allen Zhou & Samantha O. Luk. (2019) Effect of Levetiracetam on Time to High‐Dose Methotrexate Clearance in Patients With Hematologic Malignancies. The Journal of Clinical Pharmacology 60:3, pages 324-330.
Crossref
Crossref
Biljana Škorić, Marija Jovanović, Branislava Miljković, Miloš Kuzmanović & Katarina Vučićević. (2020) Clinical pharmacokinetics of methotrexate in the treatment of acute lymphoblastic leukemia and non-Hodgkin lymphoma in pediatric patients. Arhiv za farmaciju 70:1, pages 20-33.
Crossref
Crossref
Hui Li, Qiong Xu, Yang Wang, Kailan Chen & Jianxin Li. (2019) Serum neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for predicting high dose methotrexate associated acute kidney injury in children with acute lymphoblastic leukemia. Cancer Chemotherapy and Pharmacology 85:1, pages 95-103.
Crossref
Crossref
Sophie Lalevée, Bénédicte Lebrun-Vignes, Corinne Simon, Delphine Laugier & Laurence Fardet. (2019) Cytopenia induced by low-dose methotrexate: An analysis of 433 cases from the French pharmacovigilance database. European Journal of Internal Medicine 67, pages 97-101.
Crossref
Crossref
David Martinez, Kienana Muhrez, Jean-Baptiste Woillard, Aline Berthelot, Emmanuel Gyan, Sylvain Choquet, Christian R. Andrès, Pierre Marquet & Chantal Barin-Le Guellec. (2018)
Endogenous Metabolites-Mediated Communication Between OAT1/OAT3 and OATP1B1 May Explain the Association Between
SLCO1B1
SNPs and Methotrexate Toxicity
. Clinical Pharmacology & Therapeutics 104:4, pages 687-698.
Crossref
Crossref
Samuele Renzi, Ekaterina Tsimerman, Tracey Taylor, Sevan Hopyan, Alicia Koo & Abha Gupta. (2018) Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature. Journal of Pediatric Hematology/Oncology 40:6, pages e392-e393.
Crossref
Crossref
Henrik Svanström, Marie Lund, Mads Melbye & Björn Pasternak. (2018) Concomitant use of low-dose methotrexate and NSAIDs and the risk of serious adverse events among patients with rheumatoid arthritis. Pharmacoepidemiology and Drug Safety 27:8, pages 885-893.
Crossref
Crossref
Florence Ranchon, Nicolas Vantard, Emilie Henin, Emmanuel Bachy, Clémentine Sarkozy, Lionel Karlin, Fadhela Bouafia-Sauvy, Aurore Gouraud, Verane Schwiertz, Estelle Bourbon, Amandine Baudouin, Anne Gaelle Caffin, Thierry Vial, Gilles Salles & Catherine Rioufol. (2018) Delayed methotrexate elimination: Incidence, interaction with antacid drugs, and clinical consequences?. Hematological Oncology 36:2, pages 399-406.
Crossref
Crossref
Nicolas Fabresse, Bénédicte Devictor, Christel Pissier, Hervé ChambostBruno Lacarelle, Gérard MichelCaroline Solas. (2018) Plasma 7-Hydroxymethotrexate Levels Versus Methotrexate to Predict Delayed Elimination in Children Receiving High-Dose Methotrexate. Therapeutic Drug Monitoring 40:1, pages 76-83.
Crossref
Crossref
Yugo Hamada, Kenji Ikemura, Takuya Iwamoto & Masahiro Okuda. (2018) Stereoselective Inhibition of Renal Basolateral Human Organic Anion Transporter 3 by Lansoprazole Enantiomers. Pharmacology 101:3-4, pages 176-183.
Crossref
Crossref
Katsuya Narumi, Yu Sato, Masaki Kobayashi, Ayako Furugen, Kumiko Kasashi, Takehiro Yamada, Takanori Teshima & Ken Iseki. (2017) Effects of proton pump inhibitors and famotidine on elimination of plasma methotrexate: Evaluation of drug-drug interactions mediated by organic anion transporter 3. Biopharmaceutics & Drug Disposition 38:9, pages 501-508.
Crossref
Crossref
Sajal Ajmani, Yogesh Preet Singh, Shiva Prasad, Abhra Chowdhury, Amita Aggarwal, Able Lawrence, Ramnath Misra, Richa Mishra & Vikas Agarwal. (2017) Methotrexate-induced pancytopenia: a case series of 46 patients. International Journal of Rheumatic Diseases 20:7, pages 846-851.
Crossref
Crossref
Dominique Levêque, Guillaume Becker, Elise Toussaint, Luc-Matthieu Fornecker & Catherine Paillard. (2017) Clinical pharmacokinetics of methotrexate in oncology. International Journal of Pharmacokinetics 2:2, pages 137-147.
Crossref
Crossref
Jean-Baptiste WoillardJean DebordIsabelle Benz-de-BretagneFranck Saint-MarcouxPascal TurlureStéphane GiraultJulie AbrahamSylvain ChoquetPierre MarquetChantal Barin-Le Guellec. (2017) A Time-Dependent Model Describes Methotrexate Elimination and Supports Dynamic Modification of MRP2/ABCC2 Activity. Therapeutic Drug Monitoring 39:2, pages 145-156.
Crossref
Crossref
Dominique Barbolosi, Joseph Ciccolini, Bruno Lacarelle, Fabrice Barlési & Nicolas André. (2015) Computational oncology — mathematical modelling of drug regimens for precision medicine. Nature Reviews Clinical Oncology 13:4, pages 242-254.
Crossref
Crossref
Jai N. Patel & Apostolos Papachristos. (2015) Personalizing chemotherapy dosing using pharmacological methods. Cancer Chemotherapy and Pharmacology 76:5, pages 879-896.
Crossref
Crossref
Dominique Lev?que, C?line Duval, Charlotte Poulat, Benjamin Palas, Anne El Aatmani, Anne Dory, Guillaume Becker & B?n?dicte Gourieux. (2015) M?canismes des interactions pharmacocin?tiques impliquant les agents anticanc?reux oraux. Bulletin du Cancer 102:1, pages 65-72.
Crossref
Crossref
Rym Chioukh, Marie-Sophie Noel-Hudson, Sandy Ribes, Natalie Fournier, Laurent Becquemont & Celine Verstuyft. (2014) Proton Pump Inhibitors Inhibit Methotrexate Transport by Renal Basolateral Organic Anion Transporter hOAT3. Drug Metabolism and Disposition 42:12, pages 2041-2048.
Crossref
Crossref
Isabelle Benz-de Bretagne, Noël Zahr, Amélie Le Gouge, Jean-Sébastien Hulot, Caroline Houillier, Khe Hoang-Xuan, Emmanuel Gyan, Séverine Lissandre, Sylvain Choquet & Chantal Le Guellec. (2014) Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance. British Journal of Clinical Pharmacology 78:2, pages 329-342.
Crossref
Crossref
Angelo Paci, Gareth Veal, Christophe Bardin, Dominique Levêque, Nicolas Widmer, Jos Beijnen, Alain Astier & Etienne Chatelut. (2014) Review of therapeutic drug monitoring of anticancer drugs part 1 – Cytotoxics. European Journal of Cancer 50:12, pages 2010-2019.
Crossref
Crossref
Petra Langerová, Michal Prokeš, Martin Konvalinka, Jana Fürstová & Karel Urbánek. (2013) Incidence of potential drug interactions in medication prescriptions for children and adolescents in the University Hospital Olomouc, Czech Republic. European Journal of Pediatrics 172:5, pages 631-638.
Crossref
Crossref
A. Jarfaut, R. Santucci, D. Levêque & R. Herbrecht. (2013) Severe methotrexate toxicity due to a concomitant administration of ciprofloxacin. Médecine et Maladies Infectieuses 43:1, pages 39-41.
Crossref
Crossref