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Drug Profile

Pharmacologic and clinical profile of dexamethasone intravitreal implant

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Pages 629-647 | Published online: 10 Jan 2014

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Read on this site (4)

Dhanashree Ratra, Atanu Barh, Manideepa Banerjee, Vineet Ratra & Jyotirmay Biswas. (2018) Safety and Efficacy of Intravitreal Dexamethasone Implant for Refractory Uveitic Macular Edema in Adults and Children. Ocular Immunology and Inflammation 26:7, pages 1034-1040.
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Ilias Georgalas, Petros Petrou, Dimitrios Papakonstantinou, Vagelis Droumouchtsis & Ioannis Tservakis. (2015) Post-operative refractory cystoid macular edema in a vitrectomized eye treated with slow-release dexamethasone implant (Ozurdex). Cutaneous and Ocular Toxicology 34:3, pages 257-259.
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Irini P. Chatziralli, Adil Jaulim, Vasileios G. Peponis, Panagiotis G. Mitropoulos & Marilita M. Moschos. (2014) Branch Retinal Vein Occlusion: Treatment Modalities: An Update of the Literature. Seminars in Ophthalmology 29:2, pages 85-107.
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Articles from other publishers (22)

Jooseppi Puranen, Veli-Pekka Ranta, Marika Ruponen, Arto Urtti & Amir Sadeghi. (2023) Quantitative intravitreal pharmacokinetics in mouse as a step towards inter-species translation. Experimental Eye Research 235, pages 109638.
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Martyna Padjasek, Anna Cisło-Sankowska, Anna Lis-Bartos, Badr Qasem & Krzysztof Marycz. (2023) PLDLA/TPU Matrix Enriched with Cyclosporine A as a Therapeutic Platform for Immune-Mediated Keratitis (IMMK) in Horses. International Journal of Molecular Sciences 24:6, pages 5735.
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Mark A. Costello, Joseph Liu, Yan Wang, Bin Qin, Xiaoming Xu, Qi Li, Nathaniel A. Lynd & Feng Zhang. (2023) Reverse engineering the Ozurdex dexamethasone intravitreal implant. International Journal of Pharmaceutics 634, pages 122625.
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Xing Du, Yanjuan Sheng, Yeqiang Shi, Min Du, Yuanyuan Guo & Shanshan Li. (2022) The Efficacy of Simultaneous Injection of Dexamethasone Implant and Ranibizumab Into Vitreous Cavity on Macular Edema Secondary to Central Retinal Vein Occlusion. Frontiers in Pharmacology 13.
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Hasan ÖNCÜL, Fatma YILMAZ ÖNCÜL & Fuat ALAKUŞ. (2022) Diabetic retinopathy treatment and management during the COVID-19 pandemic. Journal of Surgery and Medicine 6:3, pages 336-341.
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Susan Lee, Laszlo Romoda & Michael Robinson. 2021. Ophthalmic Product Development. Ophthalmic Product Development 513 545 .
Kyung Tae Kim, Hwanho Lee, Jin Young Kim, Ju Byung Chae, Sungmin Hyung & Dong Yoon Kim. (2020) Association between Early Anatomic Response and Intraocular Pressure Change after Intravitreal Dexamethasone Implant: An Optical Coherence Tomography Study. Journal of Clinical Medicine 9:9, pages 2692.
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Lixia Luo, Jin Yang, Yumin Oh, Matthew J. Hartsock, Shiyu Xia, Yoo-Chun Kim, Zheng Ding, Tuo Meng, Charles G. Eberhart, Laura M. Ensign, Jennifer E. Thorne, Walter J. Stark, Elia J. Duh, Qingguo Xu & Justin Hanes. (2019) Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis. Journal of Controlled Release 296, pages 68-80.
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Javier Zarranz-Ventura, Anna Sala-Puigdollers, Daniel Velazquez-Villoria, Marc Figueras-Roca, Sergio Copete, Laura Distefano, Anna Boixadera, Jose García-Arumi & Alfredo Adan. (2019) Long-term probability of intraocular pressure elevation with the intravitreal dexamethasone implant in the real-world. PLOS ONE 14:1, pages e0209997.
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Partha Biswas, Krishnendu Nandi, Sneha Batra, Aniket Ginodia & Preeyam Biswas. (2018) Pars plana vitrectomy and re-directing a dexamethasone implant into vitreous cavity following misdirected entry into the crystalline lens. Indian Journal of Ophthalmology 66:7, pages 1033.
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Xiaoxin Li, Ningli Wang, Xiaoling Liang, Gezhi Xu, Xiao-Yan Li, Jenny Jiao, Jean Lou & Yehia Hashad. (2017) Safety and efficacy of dexamethasone intravitreal implant for treatment of macular edema secondary to retinal vein occlusion in Chinese patients: randomized, sham-controlled, multicenter study. Graefe's Archive for Clinical and Experimental Ophthalmology 256:1, pages 59-69.
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Claudia FabianiAntonio VitaleGiacomo EmmiGiuseppe LopalcoLorenzo VannozziDaniela BacheriniSilvana GuerrieroRosa Anna FavaleFiorella FuscoRossella FranceschiniBruno FredianiFlorenzo IannoneMauro GaleazziGian Marco TosiLuca Cantarini. (2017) Systemic Steroid Sparing Effect of Intravitreal Dexamethasone Implant in Chronic Noninfectious Uveitic Macular Edema. Journal of Ocular Pharmacology and Therapeutics 33:7, pages 549-555.
Crossref
David G. Callanan, Anat Loewenstein, Sunil S. Patel, Pascale Massin, Borja Corcóstegui, Xiao-Yan Li, Jenny Jiao, Yehia Hashad & Scott M. Whitcup. (2016) A multicenter, 12-month randomized study comparing dexamethasone intravitreal implant with ranibizumab in patients with diabetic macular edema. Graefe's Archive for Clinical and Experimental Ophthalmology 255:3, pages 463-473.
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Scott M. Whitcup & Michael R. Robinson. (2015) Development of a dexamethasone intravitreal implant for the treatment of noninfectious posterior segment uveitis. Annals of the New York Academy of Sciences 1358:1, pages 1-12.
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Rahul N. Khurana & Travis C. Porco. (2015) EFFICACY AND SAFETY OF DEXAMETHASONE INTRAVITREAL IMPLANT FOR PERSISTENT UVEITIC CYSTOID MACULAR EDEMA. Retina 35:8, pages 1640-1646.
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Swetha Palla, Jyotirmay Biswas & ChokkahalliK Nagesha. (2015) Efficacy of Ozurdex implant in treatment of noninfectious intermediate uveitis. Indian Journal of Ophthalmology 63:10, pages 767.
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Rahul N. Khurana, James D. Palmer, Travis C. Porco & Mark R. Wieland. (2015) Dexamethasone Intravitreal Implant for Pseudophakic Cystoid Macular Edema in Patients With Diabetes. Ophthalmic Surgery, Lasers and Imaging Retina 46:1, pages 56-61.
Crossref
Rahul BhagatJean ZhangSidiq FarooqXiao-Yan Li. (2014) Comparison of the Release Profile and Pharmacokinetics of Intact and Fragmented Dexamethasone Intravitreal Implants in Rabbit Eyes. Journal of Ocular Pharmacology and Therapeutics 30:10, pages 854-858.
Crossref
Francesco SemeraroAndrea RussoDamiano RizzoniPaola DanziFrancesco MorescalchiCiro Costagliola. (2014) Diameters and Wall-to-Lumen Ratio of Retinal Arterioles in Patients with Retinal Vein Occlusion Before and After Treatment with Dexamethasone Intravitreal Implants. Journal of Ocular Pharmacology and Therapeutics 30:7, pages 573-579.
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Brian C. Gilger, Riccardo Stoppini, David A. Wilkie, Alison B. Clode, Nelson H. Pinto, Julie Hempstead, Joseph Gerding & Jacklyn H. Salmon. (2013) Treatment of immune‐mediated keratitis in horses with episcleral silicone matrix cyclosporine delivery devices. Veterinary Ophthalmology 17:s1, pages 23-30.
Crossref
Susan S. Lee, Michael R. Robinson & Scott M. Whitcup. 2014. Ocular Pharmacology and Toxicology. Ocular Pharmacology and Toxicology 119 142 .
Brian C. Gilger. 2014. Ocular Pharmacology and Toxicology. Ocular Pharmacology and Toxicology 1 6 .

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