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Review

Combined analysis of the glia secretome and the CSF proteome: neuroinflammation and novel biomarkers

Pages 263-274 | Published online: 09 Jan 2014

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Ruqayya Afridi, Won-Ha Lee, Jong-Heon Kim & Kyoungho Suk. (2023) Utilizing databases for astrocyte secretome research. Expert Review of Proteomics 0:0, pages 1-9.
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Mithilesh Kumar Jha & Kyoungho Suk. (2013) Glia-based biomarkers and their functional role in the CNS. Expert Review of Proteomics 10:1, pages 43-63.
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Kristy J Brown, Catherine A Formolo, Haeri Seol, Ramya L Marathi, Stephanie Duguez, Eunkyung An, Dinesh Pillai, Javad Nazarian, Brian R Rood & Yetrib Hathout. (2012) Advances in the proteomic investigation of the cell secretome. Expert Review of Proteomics 9:3, pages 337-345.
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Rebekka Wittrahm, Mari Takalo, Teemu Kuulasmaa, Petra M. Mäkinen, Petri Mäkinen, Saša Končarević, Vadim Fartzdinov, Stefan Selzer, Tarja Kokkola, Leila Antikainen, Henna Martiskainen, Susanna Kemppainen, Mikael Marttinen, Heli Jeskanen, Hannah Rostalski, Eija Rahunen, Miia Kivipelto, Tiia Ngandu, Teemu Natunen, Jean-Charles Lambert, Rudolph E. Tanzi, Doo Yeon Kim, Tuomas Rauramaa, Sanna-Kaisa Herukka, Hilkka Soininen, Markku Laakso, Ian Pike, Ville Leinonen, Annakaisa Haapasalo & Mikko Hiltunen. (2023) Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models. Neurobiology of Disease 182, pages 106140.
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Timo Eninger, Stephan A. Müller, Mehtap Bacioglu, Manuel Schweighauser, Marius Lambert, Luis F. Maia, Jonas J. Neher, Sarah M. Hornfeck, Ulrike Obermüller, Gernot Kleinberger, Christian Haass, Philipp J. Kahle, Matthias Staufenbiel, Lingyan Ping, Duc M. Duong, Allan I. Levey, Nicholas T. Seyfried, Stefan F. Lichtenthaler, Mathias Jucker & Stephan A. Kaeser. (2022) Signatures of glial activity can be detected in the CSF proteome. Proceedings of the National Academy of Sciences 119:24.
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Diana Salikhova, Tatiana Bukharova, Elvira Cherkashova, Daria Namestnikova, Georgy Leonov, Maria Nikitina, Ilya Gubskiy, Gevorg Akopyan, Andrey Elchaninov, Konstantin Midiber, Natalia Bulatenco, Victoria Mokrousova, Andrey Makarov, Konstantin Yarygin, Vladimir Chekhonin, Liudmila Mikhaleva, Timur Fatkhudinov & Dmitry Goldshtein. (2021) Therapeutic Effects of hiPSC-Derived Glial and Neuronal Progenitor Cells-Conditioned Medium in Experimental Ischemic Stroke in Rats. International Journal of Molecular Sciences 22:9, pages 4694.
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Ana V. Domingues, Inês M. Pereira, Helena Vilaça-Faria, António J. Salgado, Ana J. Rodrigues & Fábio G. Teixeira. (2020) Glial cells in Parkinson´s disease: protective or deleterious?. Cellular and Molecular Life Sciences 77:24, pages 5171-5188.
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Hélène Hirbec, Nicole Déglon, Lynette C. Foo, Inbal Goshen, Jaime Grutzendler, Emilie Hangen, Tirzah Kreisel, Nathalie Linck, Julien Muffat, Sara Regio, Sybille Rion & Carole Escartin. (2020) Emerging technologies to study glial cells. Glia 68:9, pages 1692-1728.
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Jong-Heon Kim, Su-Hyeong Park, Jin Han, Pan-Woo Ko, Dongseop Kwon & Kyoungho Suk. (2020) Gliome database: a comprehensive web-based tool to access and analyze glia secretome data. Database 2020.
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Jeffrey M. Lake & Timothy D. Veenstra. 2017. The Molecular Basis of Human Cancer. The Molecular Basis of Human Cancer 103 119 .
Benjamin A. Neely, Jennifer L. Soper, Frances M. D. Gulland, P. Darwin Bell, Mark Kindy, John M. Arthur & Michael G. Janech. (2015) Proteomic analysis of cerebrospinal fluid in California sea lions ( Zalophus californianus ) with domoic acid toxicosis identifies proteins associated with neurodegeneration . PROTEOMICS 15:23-24, pages 4051-4063.
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Sanna Byström, Burcu Ayoglu, Anna Häggmark, Nicholas Mitsios, Mun-Gwan Hong, Kimi Drobin, Björn Forsström, Claudia Fredolini, Mohsen Khademi, Sandra Amor, Mathias Uhlén, Tomas Olsson, Jan Mulder, Peter Nilsson & Jochen M. Schwenk. (2014) Affinity Proteomic Profiling of Plasma, Cerebrospinal Fluid, and Brain Tissue within Multiple Sclerosis. Journal of Proteome Research 13:11, pages 4607-4619.
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Mithilesh Kumar Jha, Jae-Hong Kim & Kyoungho Suk. (2014) Proteome of brain glia: The molecular basis of diverse glial phenotypes. PROTEOMICS 14:4-5, pages 378-398.
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Kristin R Wildsmith, Stephen P Schauer, Ashley M Smith, David Arnott, Yuda Zhu, Joshua Haznedar, Surinder Kaur, W Mathews & Lee A Honigberg. (2014) Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics. Molecular Neurodegeneration 9:1, pages 22.
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Stephanie M. Cologna, Celine V. M. Cluzeau, Nicole M. Yanjanin, Paul S. Blank, Michelle K. Dail, Stephan Siebel, Cynthia L. Toth, Christopher A. Wassif, Andrew P. Lieberman & Forbes D. Porter. (2013) Human and mouse neuroinflammation markers in Niemann-Pick disease, type C1. Journal of Inherited Metabolic Disease 37:1, pages 83-92.
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Mithilesh Kumar Jha, Minchul Seo, Jong-Heon Kim, Byung-Gyu Kim, Je-Yoel Cho & Kyoungho Suk. (2013) The secretome signature of reactive glial cells and its pathological implications. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1834:11, pages 2418-2428.
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Hyejin Jeon, Jong-Heon Kim, Jae-Hong Kim, Won-Ha Lee, Myung-Shik Lee & Kyoungho Suk. (2012) Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity. Journal of Neuroinflammation 9:1.
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Lars Bertram & Harald Hampel. (2011) The role of genetics for biomarker development in neurodegeneration. Progress in Neurobiology 95:4, pages 501-504.
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Brian Dean. (2011) Understanding the role of inflammatory-related pathways in the pathophysiology and treatment of psychiatric disorders: evidence from human peripheral studies and CNS studies. International Journal of Neuropsychopharmacology 14:7, pages 997-1012.
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A.C. Kroksveen, J.A. Opsahl, T.T. Aye, R.J. Ulvik & F.S. Berven. (2011) Proteomics of human cerebrospinal fluid: Discovery and verification of biomarker candidates in neurodegenerative diseases using quantitative proteomics. Journal of Proteomics 74:4, pages 371-388.
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Paul Dowling & Martin Clynes. (2011) Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of disease-specific biomarkers. PROTEOMICS 11:4, pages 794-804.
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Helena Skalnikova, Jan Motlik, Suresh Jivan Gadher & Hana Kovarova. (2011) Mapping of the secretome of primary isolates of mammalian cells, stem cells and derived cell lines. PROTEOMICS 11:4, pages 691-708.
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