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Nithya Prasannan & Marie Scully. (2021) Novel antiplatelet strategies targeting VWF and GPIb. Platelets 32:1, pages 42-46.
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G. Ed Rainger, Myriam Chimen, Matthew J. Harrison, Clara M. Yates, Paul Harrison, Stephen P. Watson, Marie Lordkipanidzé & Gerard B. Nash. (2015) The role of platelets in the recruitment of leukocytes during vascular disease. Platelets 26:6, pages 507-520.
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Silvia Montoro-García, Eduard Shantsila & Gregory YH Lip. (2014) Potential value of targeting von Willebrand factor in atherosclerotic cardiovascular disease. Expert Opinion on Therapeutic Targets 18:1, pages 43-53.
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Articles from other publishers (58)
Jessica C. Cardenas. 2023. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology
687
695
.
Madeleine Johansson, Hong Yan, Charlotte Welinder, Ákos Végvári, Viktor Hamrefors, Magnus Bäck, Richard Sutton & Artur Fedorowski. (2022) Plasma proteomic profiling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways. Scientific Reports 12:1.
Crossref
Crossref
Shanshan Zhang, Yuan Zhou, Ruoqi Li, Zhong Chen & Xiang Fan. (2022) Advanced drug delivery system against ischemic stroke. Journal of Controlled Release 344, pages 173-201.
Crossref
Crossref
Shalki Choudhary, Kajal Sharma & Pankaj Kumar Singh. (2021) Von Willebrand factor: A key glycoprotein involved in thrombo-inflammatory complications of COVID-19. Chemico-Biological Interactions 348, pages 109657.
Crossref
Crossref
Ge Yang & Yuanyu Huang. 2021. Aptamers for Medical Applications. Aptamers for Medical Applications
129
178
.
Guoqing Wang, Xiangpeng Shen, Qiangyuan Tian, Thangavel Lakshmipriya & Subash C.B. Gopinath. (2020) The Correlation Between Ischemic Stroke and Thrombosis by Nanoscale Biomarker Analysis. Current Nanoscience 16:5, pages 676-684.
Crossref
Crossref
Thomas Hoefer, Akshita Rana, Be'eri Niego, Shweta Jagdale, Hugo J. Albers, Elizabeth E. Gardiner, Robert K. Andrews, Andries D. Van der Meer, Christoph E. Hagemeyer & Erik Westein. (2020) Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation <i>in vitro</i>. Haematologica 106:11, pages 2874-2884.
Crossref
Crossref
Katarina D. Kovacevic, Bernd Jilma, Shuhao Zhu, James C. Gilbert, Max-Paul Winter, Aurel Toma, Christian Hengstenberg, Irene Lang, Jacek Kubica & Jolanta M. Siller-Matula. (2020) von Willebrand Factor Predicts Mortality in ACS Patients Treated with Potent P2Y12 Antagonists and is Inhibited by Aptamer BT200 Ex Vivo. Thrombosis and Haemostasis 120:09, pages 1282-1290.
Crossref
Crossref
Shuhao Zhu, James C. Gilbert, Paul Hatala, Warren Harvey, Zicai Liang, Shan Gao, Daiwu Kang & Bernd Jilma. (2020) The development and characterization of a long acting anti‐thrombotic von Willebrand factor (VWF) aptamer. Journal of Thrombosis and Haemostasis 18:5, pages 1113-1123.
Crossref
Crossref
Nigel Mackman, Wolfgang Bergmeier, George A. Stouffer & Jeffrey I. Weitz. (2020) Therapeutic strategies for thrombosis: new targets and approaches. Nature Reviews Drug Discovery 19:5, pages 333-352.
Crossref
Crossref
Thien Ngo, Keunyoung Kim, Yiying Bian, Gibeom Nam, Hyun‐Ju Park, Kiho Lee, Geum‐Sil Cho, Jei‐Man Ryu, Kyung‐Min Lim & Jin‐Ho Chung. (2020) Antithrombotic effect of SP‐8008, a benzoic acid derivative, through the selective inhibition of shear stress‐induced platelet aggregation. British Journal of Pharmacology 177:4, pages 929-944.
Crossref
Crossref
Katarina D. Kovacevic, Florian J. Mayer, Bernd Jilma, Nina Buchtele, Georg Obermayer, Christoph J. Binder, Andrew D. Blann, Erich Minar, Martin Schillinger & Matthias Hoke. (2019) Von Willebrand factor antigen levels predict major adverse cardiovascular events in patients with carotid stenosis of the ICARAS study. Atherosclerosis 290, pages 31-36.
Crossref
Crossref
Thien Ngo, Keunyoung Kim, Yiying Bian, Hakjun Noh, Kyung-Min Lim, Jin-Ho Chung & Ok-Nam Bae. (2019) Antithrombotic Effects of Paeoniflorin from Paeonia suffruticosa by Selective Inhibition on Shear Stress-Induced Platelet Aggregation. International Journal of Molecular Sciences 20:20, pages 5040.
Crossref
Crossref
Walter J. Janse van Rensburg. (2019) Molecular suitability of the chacma baboon in human‐targeted Von Willebrand factor directed studies. Journal of Medical Primatology 48:3, pages 171-175.
Crossref
Crossref
Weibin Li, Meng Zhao, Huihui Yan, Kaiyu Wang & XIaopeng lan. (2019) Aptamer Oligonucleotides as Potential Therapeutics in Hematologic Diseases. Mini-Reviews in Medicinal Chemistry 19:10, pages 788-795.
Crossref
Crossref
Monika Haemmerle, Rebecca L. Stone, David G. Menter, Vahid Afshar-Kharghan & Anil K. Sood. (2018) The Platelet Lifeline to Cancer: Challenges and Opportunities. Cancer Cell 33:6, pages 965-983.
Crossref
Crossref
M. Levi, M. Scully & M. Singer. (2018) The role of ADAMTS‐13 in the coagulopathy of sepsis. Journal of Thrombosis and Haemostasis 16:4, pages 646-651.
Crossref
Crossref
Ryan Jajosky, Michael Toscano, Audrey Jajosky & Natasha Savage. (2017) Does Bernard‐Soulier syndrome protect against thrombotic thrombocytopenic purpura?. Journal of Clinical Apheresis 33:1, pages 124-125.
Crossref
Crossref
G.H. Frydman, K.A. Metcalf Pate & A. Vitsky. 2018. Comprehensive Toxicology. Comprehensive Toxicology
60
113
.
Silvia AgostiniVincenzo Lionetti. (2017) New insights into the non-hemostatic role of von Willebrand factor in endothelial protection. Canadian Journal of Physiology and Pharmacology 95:10, pages 1183-1189.
Crossref
Crossref
Erik Westein, Thomas Hoefer & Anna C. Calkin. (2017) Thrombosis in diabetes: a shear flow effect?. Clinical Science 131:12, pages 1245-1260.
Crossref
Crossref
Haifei Chen, Ailin Fu, Jing Wang, Tianqin Wu, Zhengyang Li, Jieqing Tang, Hongshi Shen, Jingjing Zhu, Jie Li, Qian Zhu & Longmei Qing. (2017) Rituximab as first-line treatment for acquired thrombotic thrombocytopenic purpura. Journal of International Medical Research 45:3, pages 1253-1260.
Crossref
Crossref
Jolanta M. Siller-Matula, Irene M. Lang, Christian Schoergenhofer, Mark Roest & Bernd Jilma. (2017) Interdependence between osteoprotegerin and active von Willebrand factor in long-term cardiovascular mortality prediction in patients undergoing percutaneous coronary intervention. Thrombosis and Haemostasis 117:09, pages 1730-1738.
Crossref
Crossref
Janina Jamasbi, Keng Ayabe, Shinya Goto, Bernhard Nieswandt, Karlheinz Peter & Wolfgang Siess. (2017) Platelet receptors as therapeutic targets: Past, present and future. Thrombosis and Haemostasis 117:07, pages 1249-1257.
Crossref
Crossref
E.A. Meyer, E. Caroff & M.A. Riederer. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
556
599
.
Sören Twarock, Saghar Bagheri, Sayeh Bagheri & Thomas Hohlfeld. (2016) Platelet–vessel wall interactions and drug effects. Pharmacology & Therapeutics 167, pages 74-84.
Crossref
Crossref
Eric M. Ostertag, Khalil Bdeir, Stephen Kacir, Michelle Thiboutot, Gayathri Gulendran, Lenka Yunk, Vincent M. Hayes, David G. Motto, Mortimer Poncz, X. Long Zheng, Douglas B. Cines & Don L. Siegel. (2016) ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model. Transfusion 56:7, pages 1775-1785.
Crossref
Crossref
Hua-qiang Yao, Fu-jun Wang & Zhen Kang. (2016) Effects of Endovascular Interventions on vWF and Fb Levels in Type 2 Diabetic Patients with Peripheral Artery Disease. Annals of Vascular Surgery 33, pages 159-166.
Crossref
Crossref
J.C. Cardenas, C.M. Rein-Smith & F.C. Church. 2016. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology
714
722
.
Minoo Shahidi. 2017. Thrombosis and Embolism: from Research to Clinical Practice. Thrombosis and Embolism: from Research to Clinical Practice
285
306
.
Rebecca S. WoodruffBruce A. Sullenger. (2015) Modulation of the Coagulation Cascade Using Aptamers. Arteriosclerosis, Thrombosis, and Vascular Biology 35:10, pages 2083-2091.
Crossref
Crossref
Michael Schwameis, Christian Schörgenhofer, Alice Assinger, Margarete M. Steiner & Bernd Jilma. (2017) VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP. Thrombosis and Haemostasis 113:04, pages 708-718.
Crossref
Crossref
Pat MetharomMichael C. BerndtRoss I. BakerRobert K. Andrews. (2015) Current State and Novel Approaches of Antiplatelet Therapy. Arteriosclerosis, Thrombosis, and Vascular Biology 35:6, pages 1327-1338.
Crossref
Crossref
Piao-Ping Hu & Kun-He Zhang. (2015) The modulation of coagulation by aptamers. Blood Coagulation & Fibrinolysis 26:1, pages 1-6.
Crossref
Crossref
Han-Mou Tsai. 2015. ADAMTS13. ADAMTS13
91
128
.
Minoo Shahidi. 2015.
Lee-Chun Su, Hao Xu, Richard T. Tran, Yi-Ting Tsai, Liping Tang, Subhash Banerjee, Jian Yang & Kytai T. Nguyen. (2014)
In Situ
Re-endothelialization
via
Multifunctional Nanoscaffolds
. ACS Nano 8:10, pages 10826-10836.
Crossref
Crossref
Jeong-Hyun Ryou, Keunwan Park, Joong-jae Lee, Dongsup Kim & Hak-Sung Kim. (2014) Soluble expression of human glycoprotein Ibα in Escherichia coli through replacement of the N-terminal capping domain. Protein Expression and Purification 101, pages 21-27.
Crossref
Crossref
Michael H. Rosove. (2014) Thrombotic microangiopathies. Seminars in Arthritis and Rheumatism 43:6, pages 797-805.
Crossref
Crossref
Ping Zhang, Lidija Covic & Athan Kuliopulos. 2014. Antiplatelet Therapy in Cardiovascular Disease. Antiplatelet Therapy in Cardiovascular Disease
29
44
.
Carina Hillgruber, Annika K. Steingräber, Birgit Pöppelmann, Cécile V. Denis, Jerry Ware, Dietmar Vestweber, Bernhard Nieswandt, Stefan W. Schneider & Tobias Goerge. (2014) Blocking Von Willebrand Factor for Treatment of Cutaneous Inflammation. Journal of Investigative Dermatology 134:1, pages 77-86.
Crossref
Crossref
Trung C. Nguyen, Yong Y. Han, James D. Fortenberry, Zhou Zhou, Miguel A. Cruz & Joseph A. CarcilloJr.Jr.. 2014. Pediatric Critical Care Medicine. Pediatric Critical Care Medicine
481
492
.
Stefania MomiMichela TantucciMaarten Van Roy, Hans Ulrichts, Giovanni Ricci & Paolo Gresele. (2013) Reperfusion of cerebral artery thrombosis by the GPIb–VWF blockade with the Nanobody ALX-0081 reduces brain infarct size in guinea pigs. Blood 121:25, pages 5088-5097.
Crossref
Crossref
Jens MinnerupChristoph Kleinschnitz. (2013) No risk, no benefit: still true for antithrombotic stroke treatments?. Future Medicinal Chemistry 5:4, pages 377-379.
Crossref
Crossref
Stan Heptinstall. 2013. Antiplatelet and Anticoagulation Therapy. Antiplatelet and Anticoagulation Therapy
1
44
.
Keunyoung Kim, Ok-Nam Bae, Kyung-Min Lim, Ji-Yoon Noh, Seojin Kang, Ka Young Chung & Jin-Ho Chung. (2012) Novel Antiplatelet Activity of Protocatechuic Acid through the Inhibition of High Shear Stress-Induced Platelet Aggregation. Journal of Pharmacology and Experimental Therapeutics 343:3, pages 704-711.
Crossref
Crossref
Filip CallewaertJan Roodt, Hans UlrichtsThomas StohrWalter Janse van RensburgSeb LamprechtStefaan RossenuSofie PriemWouter Willems & Josefin-Beate Holz. (2012) Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura. Blood 120:17, pages 3603-3610.
Crossref
Crossref
Ok-Nam Bae. (2012) Targeting von Willebrand factor as a novel anti-platelet therapy; Application of ARC1779, an Anti-vWF aptamer, against thrombotic risk. Archives of Pharmacal Research 35:10, pages 1693-1699.
Crossref
Crossref
Ana-Maria Navarrete, Caterina Casari, Paulette Legendre, Isabelle Marx, Jiun-Ruey Hu, Peter J. Lenting, Olivier D. Christophe & Cécile V. Denis. (2012) A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor. Blood 120:13, pages 2723-2732.
Crossref
Crossref
Elise Bernard, Vivienne Buckley, Edelmiro Moman, Lorraine Coleman, Gerardene Meade, Dermot Kenny & Marc Devocelle. (2012) Inhibition of platelet adhesion by peptidomimetics mimicking the interactive β-hairpin of glycoprotein Ibα. Bioorganic & Medicinal Chemistry Letters 22:9, pages 3323-3326.
Crossref
Crossref
Jolanta M. Siller-MatulaYahye MerhiJean-François TanguayDaniel DuerschmiedDenisa D. WagnerKathleen E. McGinnessP. Shannon PendergrastJou-Ku ChungXianbin TianRobert G. SchaubBernd Jilma. (2012) ARC15105 Is a Potent Antagonist of Von Willebrand Factor Mediated Platelet Activation and Adhesion. Arteriosclerosis, Thrombosis, and Vascular Biology 32:4, pages 902-909.
Crossref
Crossref
Katleen Broos, Mieke Trekels, Rani Alphonsa Jose, Jonas Demeulemeester, Aline Vandenbulcke, Nele Vandeputte, Tom Venken, Brecht Egle, Wim M. De Borggraeve, Hans Deckmyn & Marc De Maeyer. (2012) Identification of a Small Molecule That Modulates Platelet Glycoprotein Ib-von Willebrand Factor Interaction. Journal of Biological Chemistry 287:12, pages 9461-9472.
Crossref
Crossref
Simon F. De MeyerGuido StollDenisa D. WagnerChristoph Kleinschnitz. (2012) von Willebrand Factor. Stroke 43:2, pages 599-606.
Crossref
Crossref
Petra Jilma-Stohlawetz, Paul Knöbl, James C. Gilbert & Bernd Jilma. (2017) The anti-von Willebrand factor aptamer ARC1779 increases von Willebrand factor levels and platelet counts in patients with type 2B von Willebrand disease. Thrombosis and Haemostasis 108:08, pages 284-290.
Crossref
Crossref
Xuebin Ji & Ming Hou. (2011) Novel agents for anti-platelet therapy. Journal of Hematology & Oncology 4:1.
Crossref
Crossref
D. KAIREVICIUTE, G.Y.H. LIP, B. BALAKRISHNAN, G. UZDAVINYS, G. NORKUNAS, G. KALINAUSKAS, V. SIRVYDIS, A. AIDIETIS, U. ZANETTO, H. SIHOTA, M. MAHESHWARI & A.D. BLANN. (2011) Intracardiac expression of markers of endothelial damage/dysfunction, inflammation, thrombosis, and tissue remodeling, and the development of postoperative atrial fibrillation. Journal of Thrombosis and Haemostasis 9:12, pages 2345-2352.
Crossref
Crossref
Petra Jilma-Stohlawetz, James Gilbert, Monika Gorczyca, Paul Knöbl & Bernd Jilma. (2017) A dose ranging phase I/II trial of the von Willebrand factor inhibiting aptamer ARC1779 in patients with congenital thrombotic thrombo - cytopenic purpura. Thrombosis and Haemostasis 106:09, pages 391-397.
Crossref
Crossref
Janine E. van Loon, Peter P. T de Jaegere, Huub H. D. M van Vliet, Moniek P. M de Maat, Philip G. de Groot, Maarten L. Simoons & Frank W. G. Leebeek. (2017) The in vitro effect of the new antithrombotic drug candidate ALX-0081 on blood samples of patients undergoing percutaneous coronary intervention. Thrombosis and Haemostasis 106:07, pages 165-171.
Crossref
Crossref