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Expert Review of Anti-infective Therapy Volume 9, 2011 - Issue 11
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Review

Immunomodulatory therapy for sepsis: an update

Eirini Christaki Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece; Infectious Disease Division, Memorial Hospital of RI, The Warren Alpert School of Medicine of Brown University, Providence, RI, USA;[email protected]
,
Panagiota Anyfanti Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece; Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
&
Steven M Opal Infectious Disease Division, Memorial Hospital of RI, The Warren Alpert School of Medicine of Brown University, Providence, RI, USA; Infectious Disease Division, Memorial Hospital of RI, The Warren Alpert School of Medicine of Brown University, Providence, RI, USA
Pages 1013-1033 | Published online: 10 Jan 2014

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Peng Lu, Lei Zhang, Ting Liu, Jing-Jing Fan, Xu Luo & Yi-Tang Zhu. (2022) MiR-494-mediated Effects on the NF-κB Signaling Pathway Regulate Lipopolysaccharide-Induced Acute Kidney Injury in Mice. Immunological Investigations 51:5, pages 1372-1384.
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Hans C Hasselbalch. (2014) Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms. Expert Review of Hematology 7:2, pages 203-216.
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Jonathan S Boomer, Jonathan M Green & Richard S Hotchkiss. (2014) The changing immune system in sepsis. Virulence 5:1, pages 45-56.
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Eirini Christaki. (2013) Personalized medicine in sepsis: the coming of age. Expert Review of Anti-infective Therapy 11:7, pages 645-647.
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James D. Faix. (2013) Biomarkers of sepsis. Critical Reviews in Clinical Laboratory Sciences 50:1, pages 23-36.
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Yan Meng, Kai-wen Kong, Yong-qing Chang, Xiao-ming Deng & Tao Yang. (2023) Histone methyltransferase SETD2 inhibits M1 macrophage polarization and glycolysis by suppressing HIF-1α in sepsis-induced acute lung injury. Medical Microbiology and Immunology 212:5, pages 369-379.
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Juveria Usmani, Mohd Wasim, Mohd Nazam Ansari, Mohammed Jaseem Hassan, Manju Sharma & Razi Ahmad. (2023) Potential therapeutic effect of Carica papaya leaves extract on immune response, biochemical and hematological mechanisms on cecal ligation and puncture model of sepsis in rats: an in vivo study. 3 Biotech 13:5.
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Nana Tao, Xie Xu, Yuyuan Ying, Shiyu Hu, Qingru Sun, Guiyuan Lv & Jianli Gao. (2023) Thymosin α1 and Its Role in Viral Infectious Diseases: The Mechanism and Clinical Application. Molecules 28:8, pages 3539.
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Senthilkumar Preethy, Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Vaddi Surya Prakash, Nobunao Ikewaki, Yasunori Ikeue, Mitsuru Nagataki, Masaru Iwasaki, Rajappa Senthilkumar & Samuel J. K. Abraham. (2022) Beneficial Immune Regulation by Biological Response Modifier Glucans in COVID-19 and Their Envisaged Potentials in the Management of Sepsis. Frontiers in Immunology 13.
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Deepak Siddavaram. (2022) Successful management of cytokine storm induced acute respiratory distress syndrome secondary to H1N1 influenza with itolizumab: A case series. IP Indian Journal of Immunology and Respiratory Medicine 7:1, pages 43-46.
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Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Olaf L. Cremer, Marcus J. Schultz, Marc M. J. Bonten, Brendon P. Scicluna & Tom van der Poll. (2021) Association between delay in intensive care unit admission and the host response in patients with community-acquired pneumonia. Annals of Intensive Care 11:1.
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Juveria Usmani, Tahira Khan, Razi Ahmad & Manju Sharma. (2021) Potential role of herbal medicines as a novel approach in sepsis treatment. Biomedicine & Pharmacotherapy 144, pages 112337.
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Yatin Mehta, Subhal B Dixit, Kapil Zirpe, Randhir Sud, Palepu B Gopal, Parvaiz A Koul, Vijay K Mishra, Abdul S Ansari & Vijay S Chamle. (2021) Therapeutic Approaches in Modulating the Inflammatory and Immunological Response in Patients With Sepsis, Acute Respiratory Distress Syndrome, and Pancreatitis: An Expert Opinion Review. Cureus.
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Jian Chen & Haiming Wei. (2021) Immune Intervention in Sepsis. Frontiers in Pharmacology 12.
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Janos Szederjesi, Alexandra Lazar, Marius Petrisor, Adina Hutanu, Florin Tripon, Anca Meda Georgescu & Leonard Azamfirei. (2020) Genetic variability of ANG2-35G>C gene as a predictor factor in sepsis. Revista Romana de Medicina de Laborator 28:2, pages 175-184.
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Liise-anne Pirofski & Arturo Casadevall. (2020) Antimicrobial Therapy in the Context of the Damage-Response Framework: the Prospect of Optimizing Therapy by Reducing Host Damage. Antimicrobial Agents and Chemotherapy 64:2.
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Gunnar Lachmann & Konrad Reinhart. (2020) The History of Biomarkers. Critical Care Clinics 36:1, pages 1-10.
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Wei Jiang, Xiangyou Yu, Tongwen Sun, Yanfen Chai, Ping Chang, Zhongqing Chen, Jingye Pan, Zhiyong Peng, Ruilan Wang, Xiaozhi Wang, Yuan Xu, Li Yu, Qingshan Zheng & Bin Du. (2018) ADJunctive Ulinastatin in Sepsis Treatment in China (ADJUST study): study protocol for a randomized controlled trial. Trials 19:1.
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Chengyu Li, Ping Wang, Li Zhang, Min Li, Xiang Lei, Si Liu, Zhiqiao Feng, Yongming Yao, Bai Chang, Baoshan Liu & Hongcai Shang. (2018) Efficacy and safety of Xuebijing injection (a Chinese patent) for sepsis: A meta-analysis of randomized controlled trials. Journal of Ethnopharmacology 224, pages 512-521.
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Jordi Rello, Francisco Valenzuela-Sánchez, Maria Ruiz-Rodriguez & Silvia Moyano. (2017) Sepsis: A Review of Advances in Management. Advances in Therapy 34:11, pages 2393-2411.
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Yan Xu, Yan Jiang, Wentao Gai & Botao Yu. (2017) Protective role of tenuigenin on sepsis‑induced acute kidney injury in mice. Experimental and Therapeutic Medicine.
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F. Wang, J. Liu, T. Weng, K. Shen, Z. Chen, Y. Yu, Q. Huang, G. Wang, Z. Liu & S. Jin. (2017) The Inflammation Induced by Lipopolysaccharide can be Mitigated by Short-chain Fatty Acid, Butyrate, through Upregulation of IL-10 in Septic Shock. Scandinavian Journal of Immunology 85:4, pages 258-263.
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Nicole V. Tolan, Amy M. Wockenfus, Christopher D. Koch, Bridgit O. Crews, Dennis J. Dietzen & Brad S. Karon. (2017) Analytical performance of three whole blood point-of-care lactate devices compared to plasma lactate comparison methods and a flow-injection mass spectrometry method. Clinical Biochemistry 50:4-5, pages 168-173.
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Cindy Cen, Monowar Aziz & Ping Wang. 2017. Advanced Trauma and Surgery. Advanced Trauma and Surgery 211 234 .
Douglas A. Grow, John R. McCarrey & Christopher S. Navara. (2016) Advantages of nonhuman primates as preclinical models for evaluating stem cell-based therapies for Parkinson's disease. Stem Cell Research 17:2, pages 352-366.
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Aravind T. Reddy, Sowmya P. Lakshmi & Raju C. Reddy. (2016) PPAR ? in Bacterial Infections: A Friend or Foe? . PPAR Research 2016, pages 1-7.
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Han Wei Hou, Lidan Wu, Diana P. Amador-Munoz, Miguel Pinilla Vera, Anna Coronata, Joshua A. Englert, Bruce D. Levy, Rebecca M. Baron & Jongyoon Han. (2016) Broad spectrum immunomodulation using biomimetic blood cell margination for sepsis therapy. Lab on a Chip 16:4, pages 688-699.
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E. Plessers, A. Watteyn, H. Wyns, B. Pardon, P. De Backer & S. Croubels. (2015) Study of the immunomodulatory properties of gamithromycin and dexamethasone in a lipopolysaccharide inflammation model in calves. Research in Veterinary Science 103, pages 218-223.
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Maha Aly Fahmy, Ayman Ali Farghaly, Nagwa Hassan Ali Hassan & Kawthar Abdelaziz Elsayed Diab. (2015) Molecular and cytogenetic evaluation for potential genotoxicity of hydrocortisone. Asian Pacific Journal of Tropical Disease 5:9, pages 726-731.
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Sang Hoon HanJin Seok KimJun Hee WooSu Jin JeongJeon-Soo ShinYoung Soo AhnJune Myung Kim. (2015) The Effect of Bortezomib on Expression of Inflammatory Cytokines and Survival in a Murine Sepsis Model Induced by Cecal Ligation and Puncture. Yonsei Medical Journal 56:1, pages 112.
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Alpha A FowlerIIIIII, Aamer A Syed, Shelley Knowlson, Robin Sculthorpe, Don Farthing, Christine DeWilde, Christine A Farthing, Terri L Larus, Erika Martin, Donald F Brophy, Seema Gupta, Bernard J Fisher & Ramesh Natarajan. (2014) Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis. Journal of Translational Medicine 12:1.
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E. Christaki & E.J. Giamarellos‐Bourboulis. (2014) The beginning of personalized medicine in sepsis: small steps to a bright future. Clinical Genetics 86:1, pages 56-61.
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Karolina Akinosoglou & Dimitrios Alexopoulos. (2014) Use of antiplatelet agents in sepsis: A glimpse into the future. Thrombosis Research 133:2, pages 131-138.
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Katherine Chang, Catherine Svabek, Cristina Vazquez-Guillamet, Bryan Sato, David Rasche, Strother Wilson, Paul Robbins, Nancy Ulbrandt, JoAnn Suzich, Jonathan Green, Andriani C Patera, Wade Blair, Subramaniam Krishnan & Richard Hotchkiss. (2014) Targeting the programmed cell death 1: programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis. Critical Care 18:1, pages R3.
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James N Fullerton, Alastair J O'Brien & Derek W Gilroy. (2013) Pathways mediating resolution of inflammation: when enough is too much. The Journal of Pathology 231:1, pages 8-20.
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Marcel Leist & Thomas Hartung. (2013) Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice. Archives of Toxicology 87:4, pages 563-567.
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Richard S Hotchkiss, Guillaume Monneret & Didier Payen. (2013) Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach. The Lancet Infectious Diseases 13:3, pages 260-268.
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Xian-Di He, Yan Wang, Qiong Wu, Hua-Xue Wang, Zhen-Dong Chen, Rong-Sheng Zheng, Zi-Shu Wang, Jun-Bin Wang & Yan Yang. (2013) Xuebijing Protects Rats from Sepsis Challenged with Acinetobacter baumannii by Promoting Annexin A1 Expression and Inhibiting Proinflammatory Cytokines Secretion . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-11.
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Konrad Reinhart, Michael Bauer, Niels C. Riedemann & Christiane S. Hartog. (2012) New Approaches to Sepsis: Molecular Diagnostics and Biomarkers. Clinical Microbiology Reviews 25:4, pages 609-634.
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Ibtesam Abbass Hilmi. (2012) Live liver donors: Are they at a higher risk for post-operative thrombotic complications?. World Journal of Transplantation 2:1, pages 1.
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Yanna D. Rattmann, Lauro Mera de Souza, Simone M. Malquevicz-Paiva, Nessana Dartora, Guilherme Lanzi Sassaki, Philip A. J. Gorin & Marcello Iacomini. (2012) Analysis of Flavonoids from Eugenia uniflora Leaves and Its Protective Effect against Murine Sepsis . Evidence-Based Complementary and Alternative Medicine 2012, pages 1-9.
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