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Theme: Pharmacogenomic, Proteomic & Metabolomic Applications - Review

Impact of metabolizing enzymes on drug response of endocrine therapy in breast cancer

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Pages 349-365 | Published online: 09 Jan 2014

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Jemal Hussien Ahmed, Eyasu Makonnen, Alan Fotoohi, Abraham Aseffa, Rawleigh Howe & Eleni Aklillu. (2019) CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients. Cancers 11:9, pages 1353.
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Abdel B. Halim. 2019. Biomarkers, Diagnostics and Precision Medicine in the Drug Industry. Biomarkers, Diagnostics and Precision Medicine in the Drug Industry 241 273 .
Kristin J. R. Dickschen, Stefan Willmann, Georg Hempel & Michael Block. (2017) Addressing Adherence Using Genotype-Specific PBPK Modeling—Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels. Frontiers in Pharmacology 8.
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Cristina Amaral, Andreia Lopes, Carla L. Varela, Elisiário Tavares da Silva, Fernanda M.F. Roleira, Georgina Correia-da-Silva & Natércia Teixeira. (2015) Exemestane metabolites suppress growth of estrogen receptor-positive breast cancer cells by inducing apoptosis and autophagy: A comparative study with Exemestane. The International Journal of Biochemistry & Cell Biology 69, pages 183-195.
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Hiltrud Brauch & Matthias Schwab. (2014) Prediction of tamoxifen outcome by genetic variation of CYP2D6 in post-menopausal women with early breast cancer. British Journal of Clinical Pharmacology 77:4, pages 695-703.
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Pierre BaumannPilar H SaladoresMatthias Schwab. 2014. CYP2D6: Genetics, Pharmacology and Clinical Relevance. CYP2D6: Genetics, Pharmacology and Clinical Relevance 42 52 .
Jana C. Precht, Werner Schroth, Kathrin Klein, Hiltrud Brauch, Evgeny Krynetskiy, Matthias Schwab & Thomas E. Mürdter. (2013) The Letrozole Phase 1 Metabolite Carbinol as a Novel Probe Drug for UGT2B7. Drug Metabolism and Disposition 41:11, pages 1906-1913.
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José Albuquerque, Carolina Ribeiro, Maria Eugenia G Naranjo, Adrián Llerena & Manuela Grazina. (2013) Characterization of CYP2D6 genotypes and metabolic profiles in the Portuguese population: pharmacogenetic implications . Personalized Medicine 10:7, pages 709-718.
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