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Expert Review of Neurotherapeutics Volume 11, 2011 - Issue 2
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Fingolimod for the treatment of relapsing multiple sclerosis

Douglas R Jeffery The Multiple Sclerosis and Movement Disorders Center at Advance Neurology at Cornerstone Health Care, Winston-Salem, NC 27006, USA. [email protected]; The Multiple Sclerosis and Movement Disorders Center at Advance Neurology at Cornerstone Health Care, Winston-Salem, NC 27006, USA. [email protected]
,
Clyde E Markowitz University of Pennsylvania, Philadelphia, PA, USA; University of Pennsylvania, Philadelphia, PA, USA
,
Anthony T Reder University of Chicago, Chicago, IL, USA; University of Chicago, Chicago, IL, USA
,
Bianca Weinstock-Guttman SUNY University of Buffalo, Baird MS Center and Pediatric MS Center of Excellence, Jacobs Neurological Institute, Buffalo, NY, USA; SUNY University of Buffalo, Baird MS Center and Pediatric MS Center of Excellence, Jacobs Neurological Institute, Buffalo, NY, USA
&
Kathy Tobias Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
Pages 165-183 | Published online: 09 Jan 2014

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Ivan Adamec, Magdalena Krbot Skorić & Mario Habek. (2021) Understanding and managing autonomic dysfunction in persons with multiple sclerosis. Expert Review of Neurotherapeutics 21:12, pages 1409-1417.
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Marjorie Argollo, Federica Furfaro, Daniela Gilardi, Giulia Roda, Mariangela Allocca, Laurent Peyrin-Biroulet & Silvio Danese. (2020) Modulation of sphingosine-1-phosphate in ulcerative colitis. Expert Opinion on Biological Therapy 20:4, pages 413-420.
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Rebecca J. Watters, Xin Liu & Thomas P. Loughran$suffix/text()$suffix/text(). (2011) T-cell and natural killer-cell large granular lymphocyte leukemia neoplasias. Leukemia & Lymphoma 52:12, pages 2217-2225.
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Yiping Fan, Eyleen L K Goh & Jerry Kok Yen Chan. (2023) Neural Cells for Neurodegenerative Diseases in Clinical Trials. Stem Cells Translational Medicine 12:8, pages 510-526.
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Christina Karakosta & Christina Kourentis. (2021) Fingolimod-associated macular edema: A case report of late onset. European Journal of Ophthalmology 32:4, pages NP56-NP60.
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Beatrice Arosio, Graziamaria Corbi, Sergio Davinelli, Vienna Giordano, Daniela Liccardo, Antonio Rapacciuolo & Alessandro Cannavo. (2022) Sex Differences in Cardiovascular Diseases: A Matter of Estrogens, Ceramides, and Sphingosine 1-Phosphate. International Journal of Molecular Sciences 23:7, pages 4009.
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Haonan Liu, Molly L. Jackson, Lucy J. Goudswaard, Samantha F. Moore, James L. Hutchinson & Ingeborg Hers. (2021) Sphingosine-1-phosphate modulates PAR1-mediated human platelet activation in a concentration-dependent biphasic manner. Scientific Reports 11:1.
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Shahzad Nawaz Syed, Andreas Weigert & Bernhard Brüne. (2020) Sphingosine Kinases are Involved in Macrophage NLRP3 Inflammasome Transcriptional Induction. International Journal of Molecular Sciences 21:13, pages 4733.
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Daan van Kruining, Qian Luo, Gerhild van Echten-Deckert, Michelle M. Mielke, Andrew Bowman, Shane Ellis, Tiago Gil Oliveira & Pilar Martinez-Martinez. (2020) Sphingolipids as prognostic biomarkers of neurodegeneration, neuroinflammation, and psychiatric diseases and their emerging role in lipidomic investigation methods. Advanced Drug Delivery Reviews 159, pages 232-244.
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Anna-Karin Pada, Diti Desai, Kaiyao Sun, Narayana Prakirth Govardhanam, Kid Törnquist, Jixi Zhang & Jessica M. Rosenholm. (2019) Comparison of Polydopamine-Coated Mesoporous Silica Nanorods and Spheres for the Delivery of Hydrophilic and Hydrophobic Anticancer Drugs. International Journal of Molecular Sciences 20:14, pages 3408.
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Ainhoa Nieto Gutierrez & Patricia H. McDonald. (2018) GPCRs: Emerging anti-cancer drug targets. Cellular Signalling 41, pages 65-74.
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Zuoquan Xie, Hong Liu & Meiyu Geng. (2017) Targeting sphingosine-1-phosphate signaling for cancer therapy. Science China Life Sciences 60:6, pages 585-600.
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Inés González-Suarez, Luis Rodríguez de Antonio, Aida Orviz, Sara Moreno-García, María D. Valle-Arcos, Jordi A. Matias-Guiu, Cristina Valencia, Manuela Jorquera Moya & Celia Oreja-Guevara. (2017) Catastrophic outcome of patients with a rebound after Natalizumab treatment discontinuation. Brain and Behavior 7:4, pages e00671.
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Kunio Sugahara, Yasuhiro Maeda, Kyoko Shimano, Akira Mogami, Hirotoshi Kataoka, Kei Ogawa, Kumiko Hikida, Hiroshi Kumagai, Mahoko Asayama, Toshinobu Yamamoto, Tomohiko Harada, Pingping Ni, Shinsuke Inoue & Atsuhiro Kawaguchi. (2017) Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk. British Journal of Pharmacology 174:1, pages 15-27.
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Lillian Cruz-Orengo, Brian P. Daniels, Denise Dorsey, Sarah Alison Basak, José G. Grajales-Reyes, Erin E. McCandless, Laura Piccio, Robert E. Schmidt, Anne H. Cross, Seth D. Crosby & Robyn S. Klein. (2014) Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. Journal of Clinical Investigation 124:6, pages 2571-2584.
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Vilija G. JokubaitisVivien LiTomas KalincikGuillermo IzquierdoSuzanne HodgkinsonRaed AlroughaniJeannette Lechner-ScottAlessandra LugaresiPierre DuquetteMarc GirardMichael BarnettFrancois Grand'MaisonMaria TrojanoMark SleeGiorgio GiulianiCameron ShawCavit BozDaniele L.A. SpitaleriFreek VerheulJodi HaartsenDanny LiewHelmut Butzkueven. (2014) Fingolimod after natalizumab and the risk of short-term relapse. Neurology 82:14, pages 1204-1211.
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V.M. Asensio-Sánchez, L. Trujillo-Guzmán & R. Ramoa-Osorio. (2014) Cystoid macular oedema after fingolimod treatment in multiple sclerosis. Archivos de la Sociedad Española de Oftalmología (English Edition) 89:3, pages 104-106.
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V.M. Asensio-Sánchez, L. Trujillo-Guzmán & R. Ramoa-Osorio. (2014) Edema macular quístico por fingolimod en esclerosis múltiple. Archivos de la Sociedad Española de Oftalmología 89:3, pages 104-106.
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Ivan Adamec & Mario Habek. (2013) Autonomic dysfunction in multiple sclerosis. Clinical Neurology and Neurosurgery 115, pages S73-S78.
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Katja Thomas & Tjalf Ziemssen. (2013) Management of fingolimod in clinical practice. Clinical Neurology and Neurosurgery 115, pages S60-S64.
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Edward FoxDaniel WynnStanley CohanDonna RillDawn McGuireClyde Markowitz. (2011) A randomized clinical trial of autologous T-cell therapy in multiple sclerosis: subset analysis and implications for trial design. Multiple Sclerosis Journal 18:6, pages 843-852.
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Lauren P. Saunders, Wenxiang Cao, William C. Chang, Ronald A. Albright, Demetrios T. Braddock & Enrique M. De La Cruz. (2011) Kinetic Analysis of Autotaxin Reveals Substrate-specific Catalytic Pathways and a Mechanism for Lysophosphatidic Acid Distribution. Journal of Biological Chemistry 286:34, pages 30130-30141.
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