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Review

Understanding glioma stem cells: rationale, clinical relevance and therapeutic strategies

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Pages 545-555 | Published online: 09 Jan 2014

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Qin Xia, Liqun Liu, Yang Li, Pei Zhang, Da Han & Lei Dong. (2021) Therapeutic Perspective of Temozolomide Resistance in Glioblastoma Treatment. Cancer Investigation 39:8, pages 627-644.
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Brenda Auffinger, Drew Spencer, Peter Pytel, Atique U Ahmed & Maciej S Lesniak. (2015) The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence. Expert Review of Neurotherapeutics 15:7, pages 741-752.
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Articles from other publishers (58)

Rafał Chojak, Jawad Fares, Edgar Petrosyan & Maciej S. Lesniak. (2023) Cellular senescence in glioma. Journal of Neuro-Oncology.
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Jianxing Yin, Fangshu Ding, Zhangchun Cheng, Xin Ge, Yanhui Li, Ailiang Zeng, Junxia Zhang, Wei Yan, Zhumei Shi, Xu Qian, Yongping You, Zhiliang Ding, Jing Ji & Xiefeng Wang. (2023) METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling. Cell Death & Disease 14:7.
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Jingru Che, Thomas J. DePalma, Hemamylammal Sivakumar, Louisa S. Mezache, Miranda M. Tallman, Monica Venere, Katelyn Swindle‐Reilly, Rengasayee Veeraraghavan & Aleksander Skardal. (2023) αCT1 peptide sensitizes glioma cells to temozolomide in a glioblastoma organoid platform. Biotechnology and Bioengineering 120:4, pages 1108-1119.
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Moustafa A. Mansour, Masum Rahman, Ahmad A. Ayad, Arthur E. Warrington & Terry C. Burns. (2023) P21 Overexpression Promotes Cell Death and Induces Senescence in Human Glioblastoma. Cancers 15:4, pages 1279.
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Leili Shabani, Milad Abbasi, Masoomeh Amini, Ali Mohammad Amani & Ahmad Vaez. (2022) The brilliance of nanoscience over cancer therapy: Novel promising nanotechnology-based methods for eradicating glioblastoma. Journal of the Neurological Sciences 440, pages 120316.
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Richa Shrivastava, Puneet Gandhi & Ragini Gothalwal. (2022) The road-map for establishment of a prognostic molecular marker panel in glioma using liquid biopsy: current status and future directions. Clinical and Translational Oncology 24:9, pages 1702-1714.
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Masum Rahman, Ian Olson, Moustafa Mansour, Lucas P. Carlstrom, Rujapope Sutiwisesak, Rehan Saber, Karishma Rajani, Arthur E. Warrington, Adam Howard, Mark Schroeder, Sisi Chen, Paul A. Decker, Eliot F. Sananikone, Yi Zhu, Tamar Tchkonia, Ian F. Parney, Sandeep Burma, Desmond Brown, Moses Rodriguez, Jann N. Sarkaria, James L. Kirkland & Terry C. Burns. (2022) Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition. Molecular Cancer Research 20:6, pages 938-948.
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Zhijie Chen, Yingqian Zhong, Jiehong Chen, Shuxin Sun, Wenfeng Liu, Yu Han, Xincheng Liu, Cui Guo, Depei Li, Wanming Hu, Peiyu Zhang, Zhuopeng Chen, Zhongping Chen, Yonggao Mou, Guangmei Yan, Wenbo Zhu, Wei Yin & Ke Sai. (2022) Disruption of β-catenin-mediated negative feedback reinforces cAMP-induced neuronal differentiation in glioma stem cells. Cell Death & Disease 13:5.
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Manendra Singh Tomar, Ashok Kumar, Chhitij Srivastava & Ashutosh Shrivastava. (2021) Elucidating the mechanisms of Temozolomide resistance in gliomas and the strategies to overcome the resistance.. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1876:2, pages 188616.
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Tom M. Thomas, Ken Miyaguchi, Lincoln A. Edwards, Hongqiang Wang, Hassen Wollebo, Li Aiguo, Ramachandran Murali, Yizhou Wang, Daniel Braas, Justin S. Michael, Allen M. Andres, Miqin Zhang, Kamel Khalili, Roberta A. Gottlieb, J. Manuel Perez & John S. Yu. (2021) Elevated Asparagine Biosynthesis Drives Brain Tumor Stem Cell Metabolic Plasticity and Resistance to Oxidative Stress. Molecular Cancer Research 19:8, pages 1375-1388.
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Ling He, Kruttika Bhat, Angeliki Ioannidis, Le Zhang, Nhan T. Nguyen, Joshua E. Allen, Phioanh Leia Nghiemphu, Timothy F. Cloughesy, Linda M. Liau, Harley I. Kornblum & Frank Pajonk. (2021) Effects of the DRD2/3 antagonist ONC201 and radiation in glioblastoma. Radiotherapy and Oncology 161, pages 140-147.
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Julia Gerstmeier, Anna-Lena Possmayer, Süleyman Bozkurt, Marina E. Hoffmann, Ivan Dikic, Christel Herold-Mende, Michael C. Burger, Christian Münch, Donat Kögel & Benedikt Linder. (2021) Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide. Cancers 13:14, pages 3577.
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Yagmur Muftuoglu & Frank Pajonk. (2021) Targeting Glioma Stem Cells. Neurosurgery Clinics of North America 32:2, pages 283-289.
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Karina Biserova, Arvids Jakovlevs, Romans Uljanovs & Ilze Strumfa. (2021) Cancer Stem Cells: Significance in Origin, Pathogenesis and Treatment of Glioblastoma. Cells 10:3, pages 621.
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Joana Vieira de Castro, Céline S. Gonçalves, Eduarda P. Martins, Irene Miranda-Lorenzo, Mariana T. Cerqueira, Adhemar Longatto-Filho, Afonso A. Pinto, Rui L. Reis, Nuno Sousa, Christopher Heeschen & Bruno M. Costa. (2021) Intracellular Autofluorescence as a New Biomarker for Cancer Stem Cells in Glioblastoma. Cancers 13:4, pages 828.
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Shao-Ming Wang, Wen-Chi Lin, Hong-Yi Lin, Yen-Lin Chen, Chiung-Yuan Ko & Ju-Ming Wang. (2021) CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma. Cell Death Discovery 7:1.
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Jawad Fares, Deepak Kanojia, Alex Cordero, Ilya Ulasov & Maciej S. Lesniak. 2021. Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies. Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies 587 634 .
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Ruoyu Guan, Xiaoming Zhang & Mian Guo. (2020) Glioblastoma stem cells and Wnt signaling pathway: molecular mechanisms and therapeutic targets. Chinese Neurosurgical Journal 6:1.
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Qian Wang, Shengnan Jia, Ding Wang, Xuyang Chen, Dhan V. Kalvakolanu, Hongwu Zheng, Xiaodong Wei, Naiyan Wen, Hang Liang, Baofeng Guo & Ling Zhang. (2020) A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis. Molecular Cancer Therapeutics 19:12, pages 2542-2553.
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Valentina Lulli, Mariachiara Buccarelli, Ramona Ilari, Giorgia Castellani, Chiara De Dominicis, Alessandra Di Giamberardino, Quintino Giorgio D′Alessandris, Stefano Giannetti, Maurizio Martini, Vittorio Stumpo, Alessandra Boe, Gabriele De Luca, Mauro Biffoni, Giovanna Marziali, Roberto Pallini & Lucia Ricci-Vitiani. (2020) Mir-370-3p Impairs Glioblastoma Stem-Like Cell Malignancy Regulating a Complex Interplay between HMGA2/HIF1A and the Oncogenic Long Non-Coding RNA (lncRNA) NEAT1. International Journal of Molecular Sciences 21:10, pages 3610.
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Varun Subramaniam Venkatesh & Emil Lou. (2019) Tunneling nanotubes: A bridge for heterogeneity in glioblastoma and a new therapeutic target?. CANCER REPORTS 2:6.
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Bhaskar Basu & Mrinal K. Ghosh. (2019) Extracellular Vesicles in Glioma: From Diagnosis to Therapy. BioEssays 41:7, pages 1800245.
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Riccardo Bazzoni & Angela Bentivegna. (2019) Role of Notch Signaling Pathway in Glioblastoma Multiforme Pathogenesis. Cancers 11:3, pages 292.
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