Advanced search
Publication Cover
Expert Review of Neurotherapeutics Volume 13, 2013 - Issue 6
Submit an article Journal homepage
183
Views
26
CrossRef citations to date
0
Altmetric
Theme: Epilepsy - Special Report

Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation

Raimondo D’Ambrosio Department of Neurological Surgery, University of Washington, Seattle, WA, USA; Regional Epilepsy Center, University of Washington, Seattle, Washington, USA; Department of Neurological Surgery, University of Washington, Seattle, WA, USA; Regional Epilepsy Center, University of Washington, Seattle, Washington, USA
,
Clifford L Eastman Department of Neurological Surgery, University of Washington, Seattle, WA, USA; Department of Neurological Surgery, University of Washington, Seattle, WA, USA
,
Cinzia Fattore Department of Internal Medicine and Therapeutics, University of Pavia and National Institute of Neurology IRCCS C Mondino Foundation, Pavia, Italy; Department of Internal Medicine and Therapeutics, University of Pavia and National Institute of Neurology IRCCS C Mondino Foundation, Pavia, Italy
&
Emilio Perucca Department of Internal Medicine and Therapeutics, University of Pavia and National Institute of Neurology IRCCS C Mondino Foundation, Pavia, Italy. [email protected]; Department of Internal Medicine and Therapeutics, University of Pavia and National Institute of Neurology IRCCS C Mondino Foundation, Pavia, Italy. [email protected]
Pages 615-625 | Published online: 09 Jan 2014

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Bekalu Amare Tesfaye, Haftom Gebregergs Hailu, Kaleab Alemayehu Zewdie, Muluken Altaye Ayza & Derbew Fikadu Berhe. (2021) Montelukast: The New Therapeutic Option for the Treatment of Epilepsy. Journal of Experimental Pharmacology 13, pages 23-31.
Read now
Yifeng Du, Timothy Kemper, Jiange Qiu & Jianxiong Jiang. (2016) Defining the therapeutic time window for suppressing the inflammatory prostaglandin E2 signaling after status epilepticus. Expert Review of Neurotherapeutics 16:2, pages 123-130.
Read now

Articles from other publishers (24)

Kai Zhong, Chengyu Qian, Rui Lyu, Xinyi Wang, Zhe Hu, Jie Yu, Jing Ma & Yilu Ye. (2022) Anti-Epileptic Effect of Crocin on Experimental Temporal Lobe Epilepsy in Mice. Frontiers in Pharmacology 13.
Crossref
Rajpushpa Labh, Rachna Gupta, Manish Narang, Sumita Halder & Rajarshi Kar. (2021) Effect of valproate and add-on levetiracetam on inflammatory biomarkers in children with epilepsy. Epilepsy & Behavior 125, pages 108358.
Crossref
Na Wang, Haipeng Liu, Bingqian Ma, Ting Zhao, Yanan Chen, Yongguang Yang, Pan Zhao & Xiong Han. (2021) CSF high-mobility group box 1 is associated with drug-resistance and symptomatic etiology in adult patients with epilepsy. Epilepsy Research 177, pages 106767.
Crossref
Qing‐Lan Chen, Lu Xia, Shao‐Ping Zhong, Qiang Wang, Jing Ding & Xin Wang. (2020) Bioinformatic analysis identifies key transcriptome signatures in temporal lobe epilepsy. CNS Neuroscience & Therapeutics 26:12, pages 1266-1277.
Crossref
Parisa Kiminejad MalaieMehdi AsadiFaezeh Sadat Hosseini, Mahmood BiglarMassoud Amanlou. (2020) Synthesis, in Vivo and in Silico Studies of N-Aryl-4-(1,3-Dioxoisoindolin-2-Yl)Benzamides as an Anticonvulsant Agent . Pharmaceutical Sciences 26:1, pages 38-44.
Crossref
Sydney Zarriello, Julian P. Tuazon, Sydney Corey, Samantha Schimmel, Mira Rajani, Anna Gorsky, Diego Incontri, Bruce D. Hammock & Cesar V. Borlongan. (2019) Humble beginnings with big goals: Small molecule soluble epoxide hydrolase inhibitors for treating CNS disorders. Progress in Neurobiology 172, pages 23-39.
Crossref
Debbie Smith, Thomas Rau, Austin Poulsen, Ziven MacWilliams, David Patterson, William Kelly & David Poulsen. (2018) Convulsive seizures and EEG spikes after lateral fluid-percussion injury in the rat. Epilepsy Research 147, pages 87-94.
Crossref
Erkan AKSÖZ. (2018) Nöroinflamasyonun Epileptogenezdeki Rolü ve Antiepileptojenik Tedavide Nöroinflamasyona Yönelik Hedefler. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi 9:2, pages 130-135.
Crossref
Brad J. Kolls & Daniel T. Laskowitz. 2018. Handbook of Neuroemergency Clinical Trials. Handbook of Neuroemergency Clinical Trials 231 243 .
Kyria M. Webster, Mujun Sun, Peter Crack, Terence J. O’Brien, Sandy R. Shultz & Bridgette D. Semple. (2017) Inflammation in epileptogenesis after traumatic brain injury. Journal of Neuroinflammation 14:1.
Crossref
Vivian B. Neis, Priscila B. Rosa, Gislaine Olescowicz & Ana Lúcia S. Rodrigues. (2017) Therapeutic potential of agmatine for CNS disorders. Neurochemistry International 108, pages 318-331.
Crossref
Melissa Barker-Haliski & H. Steve White. 2017. Models of Seizures and Epilepsy. Models of Seizures and Epilepsy 83 94 .
Antonio Gambardella, Angelo Labate, Pierangelo Cifelli, Gabriele Ruffolo, Laura Mumoli, Eleonora Aronica & Eleonora Palma. (2016) Pharmacological modulation in mesial temporal lobe epilepsy: Current status and future perspectives. Pharmacological Research 113, pages 421-425.
Crossref
Avijit Dey, Xu Kang, Jiange Qiu, Yifeng Du & Jianxiong Jiang. (2016) Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside. Trends in Pharmacological Sciences 37:6, pages 463-484.
Crossref
Dennis Dlugos, Greg Worrell, Kathryn Davis, William Stacey, Jerzy Szaflarski, Andres Kanner, Sridhar Sunderam, Mike Rogawski, Patrice Jackson-Ayotunde, Tobias Loddenkemper, Beate Diehl, Brandy Fureman & Ray Dingledine. (2016) 2014 Epilepsy Benchmarks Area III: Improve Treatment Options for Controlling Seizures and Epilepsy-Related Conditions without Side Effects. Epilepsy Currents 16:3, pages 192-197.
Crossref
Omar Herrera-Vázquez, Andrea Toledo Rojas & Agnès Fleury. (2016) NEUROINFLAMACIÓN Y EPILEPSIA. TIP 19:1, pages 24-31.
Crossref
Valentina Franco, Jacqueline A. French & Emilio Perucca. (2016) Challenges in the clinical development of new antiepileptic drugs. Pharmacological Research 103, pages 95-104.
Crossref
Daniel VitantonioWeifeng XuXinling GengBrian S. Wolff, Kentaroh Takagaki, Gholam K. MotamediJian-young Wu. (2015) Emergence of dominant initiation sites for interictal spikes in rat neocortex. Journal of Neurophysiology 114:6, pages 3315-3325.
Crossref
Mansoureh Eslami, Mohammad Sayyah, Mansoureh Soleimani, Leila Alizadeh & Mahmoudreza Hadjighassem. (2015) Lipopolysaccharide preconditioning prevents acceleration of kindling epileptogenesis induced by traumatic brain injury. Journal of Neuroimmunology 289, pages 143-151.
Crossref
Kevin M. Kelly, Eric R. Miller, Eka Lepsveridze, Elena A. Kharlamov & Zakaria Mchedlishvili. (2015) Posttraumatic seizures and epilepsy in adult rats after controlled cortical impact. Epilepsy Research 117, pages 104-116.
Crossref
Emilio Perucca. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy 110 123 .
H. Steve White & Melissa Barker-Haliski. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy 52 60 .
Solomon L Moshé, Emilio Perucca, Philippe Ryvlin & Torbjörn Tomson. (2015) Epilepsy: new advances. The Lancet 385:9971, pages 884-898.
Crossref
Emilio Russo, Francesco Andreozzi, Rodolfo Iuliano, Vincenzo Dattilo, Teresa Procopio, Giuseppe Fiume, Selena Mimmi, Nicola Perrotti, Rita Citraro, Giorgio Sesti, Andrew Constanti & Giovambattista De Sarro. (2014) Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release. Brain, Behavior, and Immunity 42, pages 157-168.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.