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Expert Review of Respiratory Medicine Volume 6, 2012 - Issue 5
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Review

Management and prevention of ventilator-associated pneumonia caused by multidrug-resistant pathogens

Philip E Grgurich Massachusetts College of Pharmacy and Health Sciences, Boston, MA 02115, USA; Department of Pharmacy, Lahey Clinic Medical Center, Burlington, MA 01805, USA; Massachusetts College of Pharmacy and Health Sciences, Boston, MA 02115, USA
,
Jana Hudcova Tufts University School of Medicine, Boston, MA 02115, USA; Department of Surgical Critical Care, Lahey Clinic Medical Center, Burlington, MA 01805, USA; Tufts University School of Medicine, Boston, MA 02115, USA
,
Yuxiu Lei Center for Infectious Diseases and Prevention, Lahey Clinic Medical Center, Burlington, MA 01805, USA; Department of Pulmonary and Critical Care, Lahey Clinic Medical Center, Burlington, MA 01805, USA; Center for Infectious Diseases and Prevention, Lahey Clinic Medical Center, Burlington, MA 01805, USA
,
Akmal Sarwar Department of Pulmonary and Critical Care, Lahey Clinic Medical Center, Burlington, MA 01805, USA; Tufts University School of Medicine, Boston, MA 02115, USA; Department of Pulmonary and Critical Care, Lahey Clinic Medical Center, Burlington, MA 01805, USA
&
Donald E Craven Center for Infectious Diseases and Prevention, Lahey Clinic Medical Center, Burlington, MA 01805, USA; Tufts University School of Medicine, Boston, MA 02115, USA. [email protected]
Pages 533-555 | Published online: 09 Jan 2014

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Diana Alves, Hélder Lopes, Idalina Machado & Maria Olívia Pereira. (2022) Colistin conditioning surfaces combined with antimicrobial treatment to prevent ventilator-associated infections. Biofouling 38:6, pages 547-557.
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Gaurav Raj Dwivedi, Rekha Tyagi, Sanchita, Shubhandra Tripathi, Sanghamitra Pati, Santosh K. Srivastava, Mahendra P. Darokar & Ashok Sharma. (2018) Antibiotics potentiating potential of catharanthine against superbug Pseudomonas aeruginosa. Journal of Biomolecular Structure and Dynamics 36:16, pages 4270-4284.
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Daniyal M. Zuberi, Melita B. Ptashnick, Jun Chen Collet, Tim T.Y. Lau, Yazdan Mirzanejad & Eva E. Thomas. (2015) Mobilising for safer care: addressing structural barriers to reducing healthcare-associated infections in Vancouver, Canada. Health Sociology Review 24:2, pages 137-151.
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Omur ILBAN & Aysegul ILBAN. (2023) The relationship between renal functions and multi-drug resistant organisms in patients with ventilator-associated pneumonia. Marmara Medical Journal 36:1, pages 52-58.
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George A. Yendewa, John McLeod Griffiss, Wesley A. Gray, Amanda Healen, Howard M. Proskin, Scott A. Fulton, Mary Ann O’Riordan, Charles Hoppel, Jeffrey L. Blumer & Robert A. Salata. (2022) Dosing Colistimethate Every 8 h Results in Higher Plasma Concentrations of Active Colistin Than Every 12-Hourly Dosing without Increase in Nephrotoxicity: A Phase 1 Pharmacokinetics Trial in Healthy Adult Volunteers. Antibiotics 11:4, pages 490.
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Mark Kevin Devian, I Wayan Suranadi, I Gusti Agung Gede Utara Hartawan & I Wayan Aryabiantara. (2022) Bacterial Patterns and Sensitivity to Antibiotics in Patients Treated with Ventilators at the Intensive Care Unit of Sanglah Hospital Denpasar, Bali, Indonesia. Open Access Macedonian Journal of Medical Sciences 10:B, pages 250-254.
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Alexie Mayor, Adélaïde Chesnay, Guillaume Desoubeaux, David Ternant, Nathalie Heuzé-Vourc’h & Thomas Sécher. (2021) Therapeutic Antibodies for the Treatment of Respiratory Tract Infections—Current Overview and Perspectives. Vaccines 9:2, pages 151.
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Hammad A. Ganatra & Brian Michael Varisco. 2019. Kendig's Disorders of the Respiratory Tract in Children. Kendig's Disorders of the Respiratory Tract in Children 596 605.e2 .
Feng Xu, Lu-Lu He, Luan-Qing Che, Wen Li, Song-Min Ying, Zhi-Hua Chen & Hua-Hao Shen. (2018) Aerosolized antibiotics for ventilator-associated pneumonia: a pairwise and Bayesian network meta-analysis. Critical Care 22:1.
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T. Sécher, L. Guilleminault, K. Reckamp, I. Amanam, L. Plantier & N. Heuzé-Vourc'h. (2018) Therapeutic antibodies: A new era in the treatment of respiratory diseases?. Pharmacology & Therapeutics 189, pages 149-172.
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Juan C. Duchesne & Marquinn D. Duke. 2018. Surgical Critical Care and Emergency Surgery. Surgical Critical Care and Emergency Surgery 51 58 .
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Mohammad Sadegh Rezai, Alireza Rafiei, Fatemeh Ahangarkani, Masoumeh Bagheri-Nesami, Attieh Nikkhah, Khaironesa Shafahi, Gohar Eslami, Azin Hajalibeig & Rezvan Khajavi. (2017) Emergence of Extensively Drug Resistant Acinetobacter baumannii-Encoding Integrons and Extended-Spectrum Beta-Lactamase Genes Isolated from Ventilator-Associated Pneumonia Patients. Jundishapur Journal of Microbiology 10:7.
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Michael J. Noto, Kyle W. Becker, Kelli L. Boyd, Ann Marie Schmidt & Eric P. Skaar. (2017) RAGE-Mediated Suppression of Interleukin-10 Results in Enhanced Mortality in a Murine Model of Acinetobacter baumannii Sepsis. Infection and Immunity 85:3.
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Mohammad Hosein Kalantar Motamedi, Hashem Jarineshin, Shaban Mehrvarz, Zahra Danial, Hamid Reza Rasouli & Ali Rashidi. (2017) Bacterial Contamination of Ventilators in the Intensive Care Unit. Trauma Monthly 23:2.
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Amos Adler, N. Deborah Friedman & Dror Marchaim. (2016) Multidrug-Resistant Gram-Negative Bacilli. Infectious Disease Clinics of North America 30:4, pages 967-997.
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David E. Tabor, Li Yu, Hoyin Mok, Christine Tkaczyk, Bret R. Sellman, Yuling Wu, Vaheh Oganesyan, Tim Slidel, Hasan Jafri, Michael McCarthy, Patricia Bradford & Mark T. Esser. (2016) Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893. Antimicrobial Agents and Chemotherapy 60:9, pages 5312-5321.
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Pramod Reddy. (2016) Empiric Antibiotic Therapy of Nosocomial Bacterial Infections. American Journal of Therapeutics 23:4, pages e982-e994.
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Elizabeth CerceoSteven B. DeitelzweigBradley M. ShermanAlpesh N. Amin. (2016) Multidrug-Resistant Gram-Negative Bacterial Infections in the Hospital Setting: Overview, Implications for Clinical Practice, and Emerging Treatment Options. Microbial Drug Resistance 22:5, pages 412-431.
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Fernando G. Zampieri, Fernanda de J. Aguiar & Antonio Paulo Nassar. (2016) Nebulized Antibiotics for Ventilator-associated Pneumonia: Next Steps After the Meta-analyses. Clinical Pulmonary Medicine 23:3, pages 105-111.
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Matteo Bassetti, Tobias Welte & Richard G. Wunderink. (2016) Treatment of Gram-negative pneumonia in the critical care setting: is the beta-lactam antibiotic backbone broken beyond repair?. Critical Care 20:1.
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Dong Liu, Jing Zhang, Hai-Xia Liu, Ying-Gang Zhu & Jie-Ming Qu. (2015) Intravenous combined with aerosolised polymyxin versus intravenous polymyxin alone in the treatment of pneumonia caused by multidrug-resistant pathogens: a systematic review and meta-analysis. International Journal of Antimicrobial Agents 46:6, pages 603-609.
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L. Hua, T. S. Cohen, Y. Shi, V. Datta, J. J. Hilliard, C. Tkaczyk, J. Suzich, C. K. Stover & B. R. Sellman. (2015) MEDI4893* Promotes Survival and Extends the Antibiotic Treatment Window in a Staphylococcus aureus Immunocompromised Pneumonia Model. Antimicrobial Agents and Chemotherapy 59:8, pages 4526-4532.
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Donald E. Craven, Jana Hudcova & Jawad Rashid. (2015) Antibiotic therapy for ventilator-associated tracheobronchitis. Current Opinion in Pulmonary Medicine 21:3, pages 250-259.
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Cristina Vazquez Guillamet & Marin H. Kollef. (2015) Ventilator associated pneumonia in the ICU. Current Opinion in Pulmonary Medicine 21:3, pages 226-231.
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Teiji Sawa, Masaru Shimizu, Kiyoshi Moriyama & Jeanine P Wiener-Kronish. (2014) Association between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: a review. Critical Care 18:6.
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Christopher D. Bahl, Kelli L. Hvorecny, Andrew A. Bridges, Alicia E. Ballok, Jennifer M. Bomberger, Kyle C. Cady, George A. O'Toole & Dean R. Madden. (2014) Signature Motifs Identify an Acinetobacter Cif Virulence Factor with Epoxide Hydrolase Activity. Journal of Biological Chemistry 289:11, pages 7460-7469.
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Stephen Thacker, Ana Moran, Mihalis Lionakis, Mary-Ann A. Mastrangelo, Tripti Halder, Maria del Pilar Huby, Yong Wu & David J. Tweardy. (2014) Restoration of lung surfactant protein D by IL-6 protects against secondary pneumonia following hemorrhagic shock. Journal of Infection 68:3, pages 231-241.
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Prashant N. Mohite, Nikhil P. Patil, Bartlomeij Zych, Anna Reed, Andre R. Simon & Mohamed Amrani. (2014) Aortic Valve Replacement 10 Years After Lung Transplantation. The Annals of Thoracic Surgery 97:2, pages 681-682.
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Chien-Ming Chao, Hsin-Lan Lin & Chih-Cheng Lai. (2013) The Association Between Early Antibiotic Discontinuation and Superinfections. Critical Care Medicine 41:10, pages e297-e298.
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