Advanced search
Publication Cover
Expert Review of Vaccines Volume 10, 2011 - Issue 4
Submit an article Journal homepage
3,111
Views
575
CrossRef citations to date
0
Altmetric
Review

CpG DNA as a vaccine adjuvant

Christian Bode Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA
,
Gan Zhao Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA
,
Folkert Steinhagen Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA
,
Takeshi Kinjo Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA
&
Dennis M Klinman Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA;[email protected]
Pages 499-511 | Published online: 09 Jan 2014

Citations (575)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (45)

Tsai-Teng Tzeng, Kit Man Chai, I-Hua Chen, Ray-Yuan Chang, Jen-Ron Chiang & Shih-Jen Liu. (2023) A TLR9 agonist synergistically enhances protective immunity induced by an Alum-adjuvanted H7N9 inactivated whole-virion vaccine. Emerging Microbes & Infections 12:2.
Read now
Dylan A. Hendy, Alex Haven, Eric M. Bachelder & Kristy M. Ainslie. (2023) Preclinical developments in the delivery of protein antigens for vaccination. Expert Opinion on Drug Delivery 20:3, pages 367-384.
Read now
Bin Zhu, Tianbao Wang, Xiaoxia Wei, Yancai Zhou & Jiansheng Li. (2023) CpG DNA-triggered upregulation of TLR9 expression affects apoptosis and immune responses in human plasmacytoid dendritic cells isolated from chronic hepatitis B patients. Archives of Physiology and Biochemistry 129:2, pages 330-337.
Read now
Shixia Wang, Chang Yi Wang, Hui-Kai Kuo, Wen-Jiun Peng, Juin-Hua Huang, Be-Shen Kuo, Feng Lin, Yaw-Jen Liu, Zhi Liu, Huang-Ting Wu, Shuang Ding, Kou-Liang Hou, Jennifer Cheng, Ya-Ting Yang, Ming-Han Jiang, Min-Sheng Wang, Tony Chen, Wei Guo Xia, Ed Lin, Chung Ho Hung, Hui-Jung Chen, Zhonghao Shih, Yi Ling Lin, Valorie Ryan, Mei Mei Hu, D. Gray Heppner, Delphine C. Malherbe, Sivakumar Periasamy, Natalia Kuzmina, Chandru Subramani, Michael Hellerstein, Thomas P. Monath, Alexander Rumyantsev, Alexander Bukreyev & Farshad Guirakhoo. (2022) A novel RBD-protein/peptide vaccine elicits broadly neutralizing antibodies and protects mice and macaques against SARS-CoV-2. Emerging Microbes & Infections 11:1, pages 2724-2734.
Read now
Daniel Mekonnen, Hylemariam Mihiretie Mengist & Tengchuan Jin. (2022) SARS-CoV-2 subunit vaccine adjuvants and their signaling pathways. Expert Review of Vaccines 21:1, pages 69-81.
Read now
Jiahui Zhang, Jingyi Fan, Mariusz Skwarczynski, Rachel J Stephenson, Istvan Toth & Waleed M Hussein. (2022) Peptide-Based Nanovaccines in the Treatment of Cervical Cancer: A Review of Recent Advances. International Journal of Nanomedicine 17, pages 869-900.
Read now
Huajun Zhao, Haigang Wang, Yifei Hu, Dongqing Xu, Chunlai Yin, Qiuju Han & Jian Zhang. (2021) Chitosan Nanovaccines as Efficient Carrier Adjuvant System for IL-12 with Enhanced Protection Against HBV. International Journal of Nanomedicine 16, pages 4913-4928.
Read now
Mark Verdecia, John F. Kokai-Kun, Maura Kibbey, Sarita Acharya, Jaap Venema & Fouad Atouf. (2021) COVID-19 vaccine platforms: Delivering on a promise?. Human Vaccines & Immunotherapeutics 17:9, pages 2873-2893.
Read now
Yizhen Jin, Yuxin Zhuang, Xiaowu Dong & Mei Liu. (2021) Development of CpG oligodeoxynucleotide TLR9 agonists in anti-cancer therapy. Expert Review of Anticancer Therapy 21:8, pages 841-851.
Read now
Xiangchuan He, Longfei Ding, Kangli Cao, Haoran Peng, Chenjian Gu, Yutang Li, Duoduo Li, Lanlan Dong, Xiujing Hong, Xiangwei Wang, Meilan Fu, Chenli Qiu, Cuisong Zhu, Ziling Zhang, Shu Song, Chenguang Wang, Zhengfan Jiang, Youhua Xie, Zhongtian Qi, Chen Zhao, Ping Zhao, Xiaoyan Zhang & Jianqing Xu. (2021) A human cell-based SARS-CoV-2 vaccine elicits potent neutralizing antibody responses and protects mice from SARS-CoV-2 challenge. Emerging Microbes & Infections 10:1, pages 1555-1573.
Read now
Rajat Mudgal, Sanketkumar Nehul & Shailly Tomar. (2020) Prospects for mucosal vaccine: shutting the door on SARS-CoV-2. Human Vaccines & Immunotherapeutics 16:12, pages 2921-2931.
Read now
Ghiabe H. Guibinga, Bikash Sahay, Heather Brown, Neil Cooch, Jing Chen, Jian Yan, Charles Reed, Meerambika Mishra, Bryan Yung, Holly Pugh, Katherine Schultheis, Rianne N. Esquivel, David B. Weiner, Laurent H. Humeau, Kate E. Broderick & Trevor R.F. Smith. (2020) Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine. Human Vaccines & Immunotherapeutics 16:9, pages 2114-2122.
Read now
Cristina M Quintella, Heitor M Quintella, Mayla Rohweder & Guilherme M Quintella. (2020) Advances in patent applications related to cancer vaccine using CpG-ODN and OX40 association. Expert Opinion on Therapeutic Patents 30:4, pages 287-301.
Read now
Rachel Yuen, Jeff Kuniholm, Christina Lisk & Lee M. Wetzler. (2019) Neisserial PorB immune enhancing activity and use as a vaccine adjuvant. Human Vaccines & Immunotherapeutics 15:11, pages 2778-2781.
Read now
Nobutaka Hanagata, Xianglan Li, Min-Hua Chen, Jie Li & Shinya Hattori. (2018) Double-stranded phosphodiester cytosine-guanine oligodeoxynucleotide complexed with calcium phosphate as a potent vaccine adjuvant for activating cellular and Th1-type humoral immunities. International Journal of Nanomedicine 13, pages 43-62.
Read now
M. Usman Ishaq, A. Rafique, H.M.N. Cheema, M. Umer Ashraf, S.U. Rahman, R. Zahid Abbas & M. Shahid Mahmood. (2018) Role of cytosine-phosphate-guanosine-Oligodeoxynucleotides (CpG ODNs) as adjuvant in poultry vaccines. World's Poultry Science Journal 74:3, pages 453-462.
Read now
Krystal Herline, Eleanor Drummond & Thomas Wisniewski. (2018) Recent advancements toward therapeutic vaccines against Alzheimer’s disease. Expert Review of Vaccines 17:8, pages 707-721.
Read now
Rajnish Sahu, Richa Verma, Saurabh Dixit, Joseph U. Igietseme, Carolyn M Black, Skyla Duncan, Shree R Singh & Vida A Dennis. (2018) Future of human Chlamydia vaccine: potential of self-adjuvanting biodegradable nanoparticles as safe vaccine delivery vehicles. Expert Review of Vaccines 17:3, pages 217-227.
Read now
Hengameh Firouzmand, Mehrnosh Sahranavard, Ali Badiee, Ali Khamesipour, Seyedeh Hoda Alavizadeh, Afshin Samiei, Dina Soroush, Masoumeh Tavassoti Kheiri, Fereidoun Mahboudi & Mahmoud Reza Jaafari. (2018) The role of LPD-nanoparticles containing recombinant major surface glycoprotein of Leishmania (rgp63) in protection against leishmaniasis in murine model. Immunopharmacology and Immunotoxicology 40:1, pages 72-82.
Read now
Nobutaka Hanagata. (2017) CpG oligodeoxynucleotide nanomedicines for the prophylaxis or treatment of cancers, infectious diseases, and allergies. International Journal of Nanomedicine 12, pages 515-531.
Read now
Nasrin Mirzaei, Farkhondeh Poursina, Sharareh Moghim, Niloufar Rashidi & Hajieh Ghasemian Safaei. (2017) The study of H. pylori putative candidate factors for single- and multi-component vaccine development. Critical Reviews in Microbiology 43:5, pages 631-650.
Read now
Ludger Klimek, Oliver Pfaar, Jean Bousquet, Gabriela Senti & Thomas Kündig. (2017) Allergen immunotherapy in allergic rhinitis: current use and future trends. Expert Review of Clinical Immunology 13:9, pages 897-906.
Read now
Jianqiang Li, Mengru Bao, Jun Ge, Sulin Ren, Tong Zhou, Fengchun Qi, Xiuying Pu & Jia Dou. (2017) Research progress of therapeutic vaccines for treating chronic hepatitis B. Human Vaccines & Immunotherapeutics 13:5, pages 986-997.
Read now
Nidhi Chauhan, Sukirti Tiwari, Tessy Iype & Utkarsh Jain. (2017) An overview of adjuvants utilized in prophylactic vaccine formulation as immunomodulators. Expert Review of Vaccines 16:5, pages 491-502.
Read now
Jarad M. Schiffer, Michael M. McNeil & Conrad P. Quinn. (2016) Recent developments in the understanding and use of anthrax vaccine adsorbed: achieving more with less. Expert Review of Vaccines 15:9, pages 1151-1162.
Read now
Laure Lambricht, Alessandra Lopes, Spela Kos, Gregor Sersa, Véronique Préat & Gaëlle Vandermeulen. (2016) Clinical potential of electroporation for gene therapy and DNA vaccine delivery. Expert Opinion on Drug Delivery 13:2, pages 295-310.
Read now
Min Beom Heo, Sun-Young Kim, Wan Soo Yun & Yong Taik Lim. (2015) Sequential delivery of an anticancer drug and combined immunomodulatory nanoparticles for efficient chemoimmunotherapy. International Journal of Nanomedicine 10, pages 5981-5993.
Read now
Marina A Dobrovolskaia & Scott E McNeil. (2015) Immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics. Expert Opinion on Biological Therapy 15:7, pages 1023-1048.
Read now
Michaela Šimčíková, Kristala L. J. Prather, Duarte M. F. Prazeres & Gabriel A. Monteiro. (2015) Towards effective non-viral gene delivery vector. Biotechnology and Genetic Engineering Reviews 31:1-2, pages 82-107.
Read now
Thilini AN Mahakapuge, Alison L Every & Jean-Pierre Y Scheerlinck. (2015) Exploring local immune responses to vaccines using efferent lymphatic cannulation. Expert Review of Vaccines 14:4, pages 579-588.
Read now
Karen AO Martins, Sina Bavari & Andres M Salazar. (2015) Vaccine adjuvant uses of poly-IC and derivatives. Expert Review of Vaccines 14:3, pages 447-459.
Read now
Abid H. Banday, Salika Jeelani & Victor J. Hruby. (2015) Cancer vaccine adjuvants – recent clinical progress and future perspectives. Immunopharmacology and Immunotoxicology 37:1, pages 1-11.
Read now
Nicolas Bruffaerts, Kris Huygen & Marta Romano. (2014) DNA vaccines against tuberculosis. Expert Opinion on Biological Therapy 14:12, pages 1801-1813.
Read now
Yimei Cao. (2014) Adjuvants for foot-and-mouth disease virus vaccines: recent progress. Expert Review of Vaccines 13:11, pages 1377-1385.
Read now
Preeti Garai, Mayuri Gogoi, Ganesh Gopal, Yashwanth Radhakrishnan, Krishnadas Subhadramma Nandakumar & Dipshikha Chakravortty. (2014) The basics and advances of immunomodulators and antigen presentation: a key to development of potent memory response against pathogens. Expert Opinion on Biological Therapy 14:10, pages 1383-1397.
Read now
Ludger Klimek, Martin F Bachmann, Gabriela Senti & Thomas M Kündig. (2014) Immunotherapy of type-1 allergies with virus-like particles and CpG-motifs. Expert Review of Clinical Immunology 10:8, pages 1059-1067.
Read now
Fazren Azmi, Abdullah Al Hadi Ahmad Fuaad, Mariusz Skwarczynski & Istvan Toth. (2014) Recent progress in adjuvant discovery for peptide-based subunit vaccines. Human Vaccines & Immunotherapeutics 10:3, pages 778-796.
Read now
Deborah A Garside, Ayman Gebril, Manal Alsaadi, Natalie Nimmo, Alexander B Mullen & Valerie A Ferro. (2013) An update on the potential for male contraception: emerging options. Open Access Journal of Contraception 4, pages 1-11.
Read now
Noura B Elsedawy & Stephen J Russell. (2013) Oncolytic vaccines. Expert Review of Vaccines 12:10, pages 1155-1172.
Read now
David A Reardon, Kai W Wucherpfennig, Gordon Freeman, Catherine J Wu, E Antonio Chiocca, Patrick Y Wen, William T Curry$suffix/text()$suffix/text(), Duane A Mitchell, Peter E Fecci, John H Sampson & Glenn Dranoff. (2013) An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma. Expert Review of Vaccines 12:6, pages 597-615.
Read now
Mehrdad Dirin & Johannes Winkler. (2013) Influence of diverse chemical modifications on the ADME characteristics and toxicology of antisense oligonucleotides. Expert Opinion on Biological Therapy 13:6, pages 875-888.
Read now
Ludger Klimek & Oliver Pfaar. (2013) A comparison of immunotherapy delivery methods for allergen immunotherapy. Expert Review of Clinical Immunology 9:5, pages 465-475.
Read now
Irina Caminschi, Simone Meuter & William R. Heath. (2013) DEC-205 is a cell surface receptor for CpG oligonucleotides. OncoImmunology 2:3.
Read now
Darren R Flower. (2012) Systematic identification of small molecule adjuvants. Expert Opinion on Drug Discovery 7:9, pages 807-817.
Read now
Joseph U Igietseme, Francis O Eko & Carolyn M Black. (2011) Chlamydia vaccines: recent developments and the role of adjuvants in future formulations. Expert Review of Vaccines 10:11, pages 1585-1596.
Read now

Articles from other publishers (530)

Yi Wang, Sheng‐Lin Qiao, Jie Wang, Meng‐Zhen Yu, Nan‐Nan Wang, Muhetaerjiang Mamuti, Hong‐Wei An, Yao‐Xin Lin & Hao Wang. (2023) Engineered CpG‐Loaded Nanorobots Drive Autophagy‐Mediated Immunity for TLR9‐Positive Cancer Therapy. Advanced Materials.
Crossref
Rimsha Bhatta, Joonsu Han, Yusheng Liu, Yang Bo, David Lee, Jiadiao Zhou, Yueji Wang, Erik Russell Nelson, Qian Chen, Xiaojia Shelly Zhang, Wael Hassaneen & Hua Wang. (2023) Metabolic tagging of extracellular vesicles and development of enhanced extracellular vesicle based cancer vaccines. Nature Communications 14:1.
Crossref
Wahyu Purbiantoro, Vinh Huynh-Phuoc, Khanh Van Nguyen, Omkar Vijay Byadgi & Ta-Chih Cheng. (2023) The immunocompetence of the hemocytes, hepatopancreas, and midgut of the giant freshwater prawn Macrobrachium rosenbergii in response to reverse gavage stimulation with CpG-oligodeoxynucleotides. Aquaculture International 31:6, pages 3345-3361.
Crossref
Mahadi Hasan, Anowara Khatun & Kentaro Kogure. (2023) Intradermal Delivery of Naked mRNA Vaccines via Iontophoresis. Pharmaceutics 15:12, pages 2678.
Crossref
Romina Cecilia Russi, Diego del Balzo, Ivana Gabriela Reidel, Mariano Alonso Bivou, Noelia Flor, Agustín Lujan, Diego Sanchez, María Teresa Damiani & Carolina Veaute. (2023) Evaluation of three formulations based on Polymorphic membrane protein D in mice infected with Chlamydia trachomatis. Frontiers in Immunology 14.
Crossref
Sivakumar S. Moni, Siddig Ibrahim Abdelwahab, Aamena Jabeen, Mohamed Eltaib Elmobark, Duaa Aqaili, Gassem Ghoal, Bassem Oraibi, Abdulla Mohammed Farasani, Ahmed Ali Jerah, Mahdi Mohammed A. Alnajai & Abdul Majeed Hamad Mohammad Alowayni. (2023) Advancements in Vaccine Adjuvants: The Journey from Alum to Nano Formulations. Vaccines 11:11, pages 1704.
Crossref
Weizhong Li, Tao Wang, Arunraj M. Rajendrakumar, Gyanada Acharya, Zizhen Miao, Berin P. Varghese, Hailiang Yu, Bibek Dhakal, Tanya LeRoith, Athira Karunakaran, Wenbin Tuo & Xiaoping Zhu. (2023) An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission. Nature Communications 14:1.
Crossref
Wakana Oda, Keisuke Umemura, Koichi Ito, Yusuke Kawamoto, Yuki Takahashi & Yoshinobu Takakura. (2023) Development of potent unmethylated CpG DNA hydrogel by introducing i-motifs into long single-stranded DNA. International Journal of Pharmaceutics 646, pages 123438.
Crossref
Yao Hu, Zhongxu Luo, Zhilei Ge, Qian Li, Peihui Yang, Honglu Zhang & Huan Zhang. (2023) Morphology Dictated Immune Activation with Framework Nucleic Acids. Small 19:48.
Crossref
Samik Chakraborty, Juan Ye, Herui Wang, Mitchell Sun, Yaping Zhang, Xueyu Sang & Zhengping Zhuang. (2023) Application of toll-like receptors (TLRs) and their agonists in cancer vaccines and immunotherapy. Frontiers in Immunology 14.
Crossref
Carissa Gaghan, Matthew Browning, Abdelhamid M. Fares, Mohamed Faizal Abdul-Careem, Isabel M. Gimeno & Raveendra R. Kulkarni. (2023) In Ovo Vaccination with Recombinant Herpes Virus of the Turkey-Laryngotracheitis Vaccine Adjuvanted with CpG-Oligonucleotide Provides Protection against a Viral Challenge in Broiler Chickens. Viruses 15:10, pages 2103.
Crossref
Mark A. Brimble, Stephen M. Winston & Andrew M. Davidoff. (2023) Stowaways in the cargo: Contaminating nucleic acids in rAAV preparations for gene therapy. Molecular Therapy 31:10, pages 2826-2838.
Crossref
You-Jeong Lee & Hong-Gu Joo. (2023) Immunostimulatory activity and safety evaluation of Bordetella bronchiseptica-derived lipopolysaccharide, a new vaccine adjuvant candidate. Immunobiology 228:5, pages 152709.
Crossref
Hengqing Cui, Xinyi Zhang, Zhuanzhuan Zhang, Mengya Zhang, Tinglin Zhang, Lili Wu, Zhengmao Lu, Jie Gao & Wenjun Zhang. (2023) Killing three birds with one stone: Tumor-membrane-decorated Prussian blue nanovaccines for synergistic management of skin tumors, radiation dermatitis and wounds. Composites Part B: Engineering 264, pages 110900.
Crossref
Lazar D. Nesovic, Carsen J. Roach, Gaurav Joshi & Harvinder Singh Gill. (2023) Delivery of gold nanoparticle-conjugated M2e influenza vaccine in mice using coated microneedles. Biomaterials Science 11:17, pages 5859-5871.
Crossref
Luigi Buonaguro & Maria Tagliamonte. (2023) Peptide-based vaccine for cancer therapies. Frontiers in Immunology 14.
Crossref
Chen Meng-Han. (2023) Fish oral vaccine and mucosal immunity. Aquaculture International.
Crossref
Elaheh Gholami Parizad, Abbas Ali Imani Fooladi, Hamid Sedighian, Elham Behzadi, Jafar Amani & Afra Khosravi. (2023) Immune response induced by recombinant pres2/S-protein and a pres2-S-protein fused with a core 18-27 antigen fragment of hepatitis B virus compared to conventional HBV vaccine. Virus Genes 59:4, pages 499-514.
Crossref
Wen Tzuen Heng, Hui Xuan Lim, Kuan Onn Tan & Chit Laa Poh. (2023) Validation of Multi-epitope Peptides Encapsulated in PLGA Nanoparticles Against Influenza A Virus. Pharmaceutical Research 40:8, pages 1999-2025.
Crossref
Shuang Liang, Jianjun Yao, Dan Liu, Lang Rao, Xiaoyuan Chen & Zhaohui Wang. (2023) Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy. Advanced Materials 35:33.
Crossref
Hongze Ren, Wencong Jia, Yujie Xie, Meihua Yu & Yu Chen. (2023) Adjuvant physiochemistry and advanced nanotechnology for vaccine development. Chemical Society Reviews 52:15, pages 5172-5254.
Crossref
Francesco Tognetti, Massimiliano Biagini, Maxime Denis, Francesco Berti, Domenico Maione & Daniela Stranges. (2023) Evolution of Vaccines Formulation to Tackle the Challenge of Anti-Microbial Resistant Pathogens. International Journal of Molecular Sciences 24:15, pages 12054.
Crossref
Kairat Tabynov, Maxim Solomadin, Nurkeldi Turebekov, Meruert Babayeva, Gleb Fomin, Ganesh Yadagiri, Sankar Renu, Toktassyn Yerubayev, Nikolai Petrovsky, Gourapura J. Renukaradhya & Kaissar Tabynov. (2023) An intranasal vaccine comprising SARS-CoV-2 spike receptor-binding domain protein entrapped in mannose-conjugated chitosan nanoparticle provides protection in hamsters. Scientific Reports 13:1.
Crossref
Mukesh Kr Singh, Gurdeep Singh, Varsha Tiwari & Abhishek Tiwari. 2023. Parasitic Infections. Parasitic Infections 328 355 .
Tingmei Zhao, Yulong Cai, Yujie Jiang, Xuemei He, Yuquan Wei, Yifan Yu & Xiaohe Tian. (2023) Vaccine adjuvants: mechanisms and platforms. Signal Transduction and Targeted Therapy 8:1.
Crossref
Xiaojuan Chen, Panpan Zhang, Pengshuo Li, Guotao Wang, Jianlong Li, Ying Wu, Zhenjie Cao, Yongcan Zhou & Yun Sun. (2023) CpG ODN 1668 as TLR9 agonist mediates humpback grouper (Cromileptes altivelis) antibacterial immune responses. Fish & Shellfish Immunology 138, pages 108839.
Crossref
Tomohiro Jimura, Yuichi Kurono, Takashi Hirano, Masaki Kawabata & Masaru Yamashita. (2023) Application of phosphorylcholine derivative as mucosal adjuvant enhancing mucosal immune responses in the upper respiratory tract. Auris Nasus Larynx.
Crossref
Allison Boboltz, Sahana Kumar & Gregg A. Duncan. (2023) Inhaled drug delivery for the targeted treatment of asthma. Advanced Drug Delivery Reviews 198, pages 114858.
Crossref
Salma Bricha, Mélanie Côté-Cyr, Thomas Tremblay, Phuong Trang Nguyen, Philippe St-Louis, Denis Giguère, Denis Archambault & Steve Bourgault. (2023) Synthetic Multicomponent Nanovaccines Based on the Molecular Co-assembly of β-Peptides Protect against Influenza A Virus. ACS Infectious Diseases 9:6, pages 1232-1244.
Crossref
Arun Kumar Singh & Rishabha Malviya. (2023) DNA Vaccines to Improve Immunogenicity and Effectiveness in Cancer Vaccinations: Advancement and Developments. Current Gene Therapy 23:3, pages 170-183.
Crossref
Xiaojuan Chen, Ying Wu, Yulin Qiu, Pengshuo Li, Zhenjie Cao, Yongcan Zhou & Yun Sun. (2023) CpG ODN 2102 promotes antibacterial immune responses and enhances vaccine-induced protection in golden pompano (Trachinotus ovatus). Fish & Shellfish Immunology 137, pages 108783.
Crossref
Jinlei He, Fan Huang, Xuechun Liao, Jianhui Zhang, Shulan Wei, Yuying Xiao, Xiaoting Zheng, Zheying Zhu, Dali Chen & Jianping Chen. (2023) TLR9 agonist CpG ODN 2395 promotes the immune response against Leishmania donovani in obesity and undernutrition mice. Acta Tropica 242, pages 106921.
Crossref
Ling Li, Shihong Nie, Ting Du, Jiaxuan Zhao & Xiaoyuan Chen. (2023) DNA origami technology for biomedical applications: Challenges and opportunities. MedComm – Biomaterials and Applications 2:2.
Crossref
Tsukasa Seya, Masashi Shingai, Tomomi Kawakita & Misako Matsumoto. (2023) Two Modes of Th1 Polarization Induced by Dendritic-Cell-Priming Adjuvant in Vaccination. Cells 12:11, pages 1504.
Crossref
David L. Bauer, Louay Bachnak, Vanessa M. Limbert, Rebecca M. Horowitz, Robin L. Baudier, Shaina J. D’Souza, Victoria E. Immethun, Jonathan R Kurtz, Samuel B. Grant & James B. McLachlan. (2023) The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells. The Journal of Immunology 210:10, pages 1519-1530.
Crossref
Jiandong Liu, Tianle Cang, Congli Jiang, Kelei Li, Siyuan Liu, Haixin Wang, Meirong Wang, Yan Chen, Yan Shao & Jiankai Liu. (2023) CpG 684: an effective adjuvant for the inactivated COVID-19 vaccine in mice. Future Virology 18:7, pages 403-410.
Crossref
Zheng Li, Jianhua Zou & Xiaoyuan Chen. (2023) In Response to Precision Medicine: Current Subcellular Targeting Strategies for Cancer Therapy. Advanced Materials 35:21.
Crossref
Javier Castrodeza-Sanz, Iván Sanz-Muñoz & Jose M. Eiros. (2023) Adjuvants for COVID-19 Vaccines. Vaccines 11:5, pages 902.
Crossref
Lila Estephan, Luke Tzu-Chi Liu, Chia En Lien, Emily R. Smith, Marc Gurwith & Robert T. Chen. (2023) A Brighton Collaboration standardized template with key considerations for a benefit/risk assessment for the Medigen COVID-19 protein vaccine. Vaccine 41:15, pages 2615-2629.
Crossref
Kathryn Cole, Zaid Al-Kadhimi & James E. Talmadge. (2023) Highlights into historical and current immune interventions for cancer. International Immunopharmacology 117, pages 109882.
Crossref
Nimeet Desai, Uzma Hasan, Jeyashree K, Rajesh Mani, Meenakshi Chauhan, Suparna Mercy Basu & Jyotsnendu Giri. (2023) Biomaterial-based platforms for modulating immune components against cancer and cancer stem cells. Acta Biomaterialia 161, pages 1-36.
Crossref
Carina Brito, Camila Lourenço, Joana Magalhães, Salette Reis & Margarida Borges. (2023) Nanoparticles as a Delivery System of Antigens for the Development of an Effective Vaccine against Toxoplasma gondii. Vaccines 11:4, pages 733.
Crossref
Luis Ontiveros-Padilla, Cole J. Batty, Dylan A. Hendy, Erik S. Pena, John A. RoqueIIIIII, Rebeca T. Stiepel, Michael A. Carlock, Sean R. Simpson, Ted M. Ross, Soman N. Abraham, Herman F. Staats, Eric M. Bachelder & Kristy M. Ainslie. (2023) Development of a broadly active influenza intranasal vaccine adjuvanted with self-assembled particles composed of mastoparan-7 and CpG. Frontiers in Immunology 14.
Crossref
Jeremiah Y. Kim, Matthew G. Rosenberger, Siquan Chen, Carman KM IP, Azadeh Bahmani, Qing Chen, Jinjing Shen, Yifeng Tang, Andrew Wang, Emma Kenna, Minjun Son, Savaş Tay, Andrew L. Ferguson & Aaron P. Esser-Kahn. (2023) Discovery of New States of Immunomodulation for Vaccine Adjuvants via High Throughput Screening: Expanding Innate Responses to PRRs. ACS Central Science 9:3, pages 427-439.
Crossref
Yibo Li & Xinyuan Chen. (2023) CpG 1018 Is an Effective Adjuvant for Influenza Nucleoprotein. Vaccines 11:3, pages 649.
Crossref
Tohid Piri-Gharaghie, Abbas Doosti & Seyed Abbas Mirzaei. (2023) Novel adjuvant nano-vaccine induced immune response against Acinetobacter baumannii. AMB Express 13:1.
Crossref
Min-Chia Wu, Hsing-Chieh Wu, Jai-Wei Lee, Wan-Chen Chang & Chun-Yen Chu. (2023) A protein-based subunit vaccine with biological adjuvants provides effective protection against Pasteurella multocida in pigs. Veterinary Research 54:1.
Crossref
Yikun Xing, Justin R. Clark, James D. Chang, Dylan M. Chirman, Sabrina Green, Jacob J. Zulk, Joseph Jelinski, Kathryn A. Patras & Anthony W. Maresso. (2023) Broad protective vaccination against systemic Escherichia coli with autotransporter antigens. PLOS Pathogens 19:2, pages e1011082.
Crossref
Xin Qin, Bowen Zhang, Xiaoqin Sun, Mei Zhang, Dexuan Xiao, Shiyu Lin, Zhiqiang Liu, Weitong Cui & Yunfeng Lin. (2023) Tetrahedral-Framework Nucleic Acid Loaded with MicroRNA-155 Enhances Immunocompetence in Cyclophosphamide-Induced Immunosuppressed Mice by Modulating Dendritic Cells and Macrophages. ACS Applied Materials & Interfaces 15:6, pages 7793-7803.
Crossref
Ya-Jia Xie, Wen-Qian Liu, Dan Li, Jin-Cai Hou, Paolo Saul Coghi & Xing-Xing Fan. (2023) Overcoming Suppressive Tumor Microenvironment by Vaccines in Solid Tumor. Vaccines 11:2, pages 394.
Crossref
Fumiko Suzuki, Jun-ichi Maeyama, Ayumi Kubota, Atsushi Nishimune, Satomi Horiguchi, Takemasa Takii, Yoshimasa Urasaki, Ichiro Shimada & Sumiko Iho. (2023) Effect of cigarette smoke on mucosal vaccine response with activation of plasmacytoid dendritic cells: The outcomes of in vivo and in vitro experiments. Vaccine 41:8, pages 1447-1456.
Crossref
Xinyuan Chen. (2023) Emerging adjuvants for intradermal vaccination. International Journal of Pharmaceutics 632, pages 122559.
Crossref
Meijuan He, Tingting Xiao, Yihui Wang, Hongwei Yu, Zilin Wang, Xiangyang Shi & Han Wang. (2023) Multifunctional PVCL nanogels enable magnetic resonance imaging and immunostimulated radiotherapy of orthotopic glioblastoma. Chemical Engineering Journal 453, pages 139634.
Crossref
Beáta Biri-Kovács, Zoltán Bánóczi, Anitha Tummalapally & Ildikó Szabó. (2023) Peptide Vaccines in Melanoma: Chemical Approaches towards Improved Immunotherapeutic Efficacy. Pharmaceutics 15:2, pages 452.
Crossref
Namrata Baruah, Nadim Ahamad, Prolay Halder, Hemanta Koley & Dhirendra S. Katti. (2023) Facile synthesis of multi-faceted, biomimetic and cross-protective nanoparticle-based vaccines for drug-resistant Shigella: a flexible platform technology. Journal of Nanobiotechnology 21:1.
Crossref
Ana Maria Valencia-Hernandez, Thomas Zillinger, Zhengyu Ge, Peck S. Tan, Anton Cozijnsen, Geoffrey I. McFadden, Mireille H. Lahoud, Irina Caminschi, Winfried Barchet, William R. Heath & Daniel Fernandez-Ruiz. (2023) Complexing CpG adjuvants with cationic liposomes enhances vaccine-induced formation of liver TRM cells. Vaccine 41:5, pages 1094-1107.
Crossref
Rani S. Sellers & Keith Nelson. 2023. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 : Safety Assessment Environmental Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 : Safety Assessment Environmental Toxicologic Pathology 335 396 .
Preeti Ravindra Bhoge, Sandhya Mardhekar, Suraj Toraskar, Balamurugan Subramani & Raghavendra Kikkeri. (2022) Pairing Nanoparticles Geometry with TLR Agonists to Modulate Immune Responses for Vaccine Development. ACS Applied Bio Materials 5:12, pages 5675-5681.
Crossref
Junli Li, Lili Fu, Xiaonan Guo, Yang Yang, Jiaxin Dong, Guozhi Wang & Aihua Zhao. (2022) Novel BC02 Compound Adjuvant Enhances Adaptive and Innate Immunity Induced by Recombinant Glycoprotein E of Varicella-Zoster Virus. Vaccines 10:12, pages 2155.
Crossref
Payuda Hansoongnern, Nantawan Phecharat, Ketkaew Wasanasuk, Wantanee Tommeurd, Penpitcha Chankeeree, Chalermpol Lekcharoensuk, Ploypailin Semkum, Sunan Pinitkiatisakul & Porntippa Lekcharoensuk. (2022) Encapsidated-CpG ODN enhances immunogenicity of porcine circovirus type 2 virus-like particles. Veterinary Microbiology 275, pages 109583.
Crossref
Junjian Shen, Minghui Lin, Mengbin Ding, Ningyue Yu, Chun Yang, Deping Kong, Haitao Sun & Zongyu Xie. (2022) Tumor immunosuppressive microenvironment modulating hydrogels for second near-infrared photothermal-immunotherapy of cancer. Materials Today Bio 16, pages 100416.
Crossref
Shuo Liu, Xiaozhen Zhan, Zhenni Lin, Zonghua Liu, Jie Yang & Yi Zhang. (2022) Bacteria-like tumor vaccines progressively initiate cascade reaction for precise antigen delivery and induction of anti-tumor cellular immune response. Chemical Engineering Journal 450, pages 138136.
Crossref
Laura M. Stephens, Kathleen A. Ross, Jason S. McLellan, Balaji Narasimhan & Steven M. Varga. (2022) Long-Lasting Protection Induced by a Polyanhydride Nanovaccine against Respiratory Syncytial Virus in an Outbred Mouse Model. Journal of Virology 96:22.
Crossref
Xiaochen Gong, Yuan Gao, Jianhong Shu, Chunjing Zhang & Kai Zhao. (2022) Chitosan-Based Nanomaterial as Immune Adjuvant and Delivery Carrier for Vaccines. Vaccines 10:11, pages 1906.
Crossref
Xiaoni Shi, Kun Yang, Hetao Song, Zhidong Teng, Yun Zhang, Weihao Ding, Aofei Wang, Shuzhen Tan, Hu Dong, Shiqi Sun, Yonghao Hu & Huichen Guo. (2022) Development and Efficacy Evaluation of a Novel Nano-Emulsion Adjuvant for a Foot-and-Mouth Disease Virus-like Particles Vaccine Based on Squalane. Nanomaterials 12:22, pages 3934.
Crossref
Qilin Yi, Depeng Zhao, Lingling Wang & Linsheng Song. (2022) Interval feeding of CpG ODN ‐supplemental diets enhanced growth in juvenile Chinese mitten crab, Eriocheir sinensis . Aquaculture Research 53:16, pages 5559-5571.
Crossref
Lazar D. Nesovic, Akhilesh K. Shakya & Harvinder S. Gill. (2022) Treating allergies via skin – Recent advances in cutaneous allergen immunotherapy. Advanced Drug Delivery Reviews 190, pages 114458.
Crossref
Olivia R. Brohlin, Ryanne N. Ehrman, Fabian C. Herbert, Yalini H. Wijesundara, Arun Raja, Arezoo Shahrivarkevishahi, Shashini D. Diwakara, Ronald A. Smaldone & Jeremiah J. Gassensmith. (2022) Zeolitic Imidazolate Framework Nanoencapsulation of CpG for Stabilization and Enhancement of Immunoadjuvancy. ACS Applied Nano Materials 5:10, pages 13697-13704.
Crossref
Yi-Nan Ding, Ming Xue, Qiu-Sha Tang, Li-Jun Wang, Hui-Yan Ding, Han Li, Cheng-Cheng Gao & Wei-Ping Yu. (2022) Immunotherapy-based novel nanoparticles in the treatment of gastrointestinal cancer: Trends and challenges. World Journal of Gastroenterology 28:37, pages 5403-5419.
Crossref
Victor Araujo Correa, Amanda Izeli Portilho & Elizabeth De Gaspari. (2022) Vaccines, adjuvants and key factors for mucosal immune response. Immunology 167:2, pages 124-138.
Crossref
Arshpreet Kaur, Jeremy Baldwin, Deshkanwar Brar, Deepak B. Salunke & Nikolai Petrovsky. (2022) Toll-like receptor (TLR) agonists as a driving force behind next-generation vaccine adjuvants and cancer therapeutics. Current Opinion in Chemical Biology 70, pages 102172.
Crossref
Weixiong Pan, Zengjue Zhao, Jiahui Wu, Qin Fan, Haobin Huang, Rongxiao He, Haokun Shen, Zitong Zhao, Saixiang Feng, Guanhua Gan, Zhiyang Chen, Miaopeng Ma, Chongjun Sun & Linghua Zhang. (2022) LACpG10-HL Functions Effectively in Antibiotic-Free and Healthy Husbandry by Improving the Innate Immunity. International Journal of Molecular Sciences 23:19, pages 11466.
Crossref
Tania H. Mulherkar, Daniel Joseph Gómez, Grace Sandel & Pooja Jain. (2022) Co-Infection and Cancer: Host–Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses. Viruses 14:9, pages 2037.
Crossref
Zhi-Mei Liu, Ming-Hui Yang, Kun Yu, Zheng-Xing Lian & Shou-Long Deng. (2022) Toll-like receptor (TLRs) agonists and antagonists for COVID-19 treatments. Frontiers in Pharmacology 13.
Crossref
Tong-yuan Yang, Manuela Braun, Wibke Lembke, Fraser McBlane, John Kamerud, Stephen DeWall, Edit Tarcsa, Xiaodong Fang, Lena Hofer, Uma Kavita, Vijay V. Upreti, Swati Gupta, LiNa Loo, Alison J. Johnson, Rakesh Kantilal Chandode, Kay-Gunnar Stubenrauch, Maya Vinzing, Cindy Q. Xia & Vibha Jawa. (2022) Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper. Molecular Therapy - Methods & Clinical Development 26, pages 471-494.
Crossref
Ziyin Chen, Ziqi Yue, Ronghua Wang, Kaiqi Yang & Shenglong Li. (2022) Nanomaterials: A powerful tool for tumor immunotherapy. Frontiers in Immunology 13.
Crossref
Chung-Nga Ko, Shaohong Zang, Yingtang Zhou, Zhangfeng Zhong & Chao Yang. (2022) Nanocarriers for effective delivery: modulation of innate immunity for the management of infections and the associated complications. Journal of Nanobiotechnology 20:1.
Crossref
Wenhui Xue, Tingting Li, Sibo Zhang, Yingbin Wang, Minqing Hong, Lingyan Cui, Hong Wang, Yuyun Zhang, Tingting Chen, Rui Zhu, Zhenqin Chen, Lizhi Zhou, Rongwei Zhang, Tong Cheng, Qingbing Zheng, Jun Zhang, Ying Gu, Ningshao Xia & Shaowei Li. (2022) Baculovirus Display of Varicella–Zoster Virus Glycoprotein E Induces Robust Humoral and Cellular Immune Responses in Mice. Viruses 14:8, pages 1785.
Crossref
Luan Firmino-Cruz, Júlio Souza dos-Santos, Alessandra Marcia da Fonseca-Martins, Diogo Oliveira-Maciel, Gustavo Guadagnini-Perez, Victor A. Roncaglia-Pereira, Carlos H. Dumard, Francisca H. Guedes-da-Silva, Ana C. Vicente Santos, Renata G. F. Alvim, Tulio M. Lima, Federico F. Marsili, Daniel P. B. Abreu, Bartira Rossi-Bergmann, Andre M. Vale, Alessandra D’Almeida Filardy, Jerson Lima Silva, Andrea Cheble de Oliveira, Andre M. O. Gomes & Herbert Leonel de Matos Guedes. (2022) Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice. Vaccines 10:8, pages 1305.
Crossref
Diego A. Díaz-Dinamarca, Michelle L. Salazar, Byron N. Castillo, Augusto Manubens, Abel E. Vasquez, Fabián Salazar & María Inés Becker. (2022) Protein-Based Adjuvants for Vaccines as Immunomodulators of the Innate and Adaptive Immune Response: Current Knowledge, Challenges, and Future Opportunities. Pharmaceutics 14:8, pages 1671.
Crossref
Mohammad Zaki Ahmad, Ali S Alasiri, Mohammed Yahia Alasmary, MM Abdullah, Javed Ahmad, Basel A Abdel Wahab, Saif Aboud M Alqahtani, Kalyani Pathak, Gulam Mustafa, Mohammad Ahmad Khan, Riya Saikia & Urvashee Gogoi. (2022) Emerging advances in nanomedicine for breast cancer immunotherapy: opportunities and challenges. Immunotherapy 14:12, pages 957-983.
Crossref
Megan A. DeJong, M. Allison Wolf, Graham J. Bitzer, Jesse M. Hall, Emel Sen-Kilic, Jeanna M. Blake, Jonathan E. Petty, Ting Y. Wong, Mariette Barbier, John D. Campbell, Justin R. Bevere & F. Heath Damron. (2022) CpG 1018® adjuvant enhances Tdap immune responses against Bordetella pertussis in mice. Vaccine 40:35, pages 5229-5240.
Crossref
Joanna L Turley & Ed C Lavelle. (2022) Resolving adjuvant mode of action to enhance vaccine efficacy. Current Opinion in Immunology 77, pages 102229.
Crossref
Mahsa Eshkevar Vakili, Zahra Faghih, Jamal Sarvari, Mehrnoosh Doroudchi, Seyed Nezamedin Hosseini, Dieter Kabelitz & Kurosh Kalantar. (2022) Lower frequency of T stem cell memory (TSCM) cells in hepatitis B vaccine nonresponders. Immunologic Research 70:4, pages 469-480.
Crossref
Zhe Jing, Shuqing Wang, Keyuan Xu, Qian Tang, Wenjing Li, Wei Zheng, Haobo Shi, Kailing Su, Yanting Liu & Zhangyong Hong. (2022) A Potent Micron Neoantigen Tumor Vaccine GP‐Neoantigen Induces Robust Antitumor Activity in Multiple Tumor Models. Advanced Science 9:24.
Crossref
Bo Yang, Bini Zhou, Cuifeng Li, Xiaowei Li, Ziwei Shi, Yuxin Li, Chenyou Zhu, Xin Li, Yi Hua, Yufan Pan, Jian He, Tianyang Cao, Yawei Sun, Wanli Liu, Min Ge, Yuhe R. Yang, Yuanchen Dong & Dongsheng Liu. (2022) A Biostable l ‐DNA Hydrogel with Improved Stability for Biomedical Applications . Angewandte Chemie International Edition 61:30.
Crossref
Bo Yang, Bini Zhou, Cuifeng Li, Xiaowei Li, Ziwei Shi, Yuxin Li, Chenyou Zhu, Xin Li, Yi Hua, Yufan Pan, Jian He, Tianyang Cao, Yawei Sun, Wanli Liu, Min Ge, Yuhe R. Yang, Yuanchen Dong & Dongsheng Liu. (2022) A Biostable l ‐DNA Hydrogel with Improved Stability for Biomedical Applications . Angewandte Chemie 134:30.
Crossref
Ana-Maria Pantazica, Mihaela-Olivia Dobrica, Catalin Lazar, Cristina Scurtu, Catalin Tucureanu, Iuliana Caras, Irina Ionescu, Adriana Costache, Adrian Onu, Jihong Liu Clarke, Crina Stavaru & Norica Branza-Nichita. (2022) Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen. Frontiers in Immunology 13.
Crossref
Yaoying Wu, Hanning WenZachary J. Bernstein, Kelly M. Hainline, Tykia S. BlakneyKendra L. Congdon, David J. SnyderJohn H. Sampson, Luis Sanchez-PerezJoel H. Collier. (2022) Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses. Science Advances 8:29.
Crossref
Jingyi Fan, Shengbin Jin, Lachlan Gilmartin, Istvan Toth, Waleed M. Hussein & Rachel J. Stephenson. (2022) Advances in Infectious Disease Vaccine Adjuvants. Vaccines 10:7, pages 1120.
Crossref
Runle Li, Mingyuan Xin, Kunmei Liu, Bingwen Hu, Jingwei Ma, Pei Zhou, Lin Feng, Mingquan Pang, Ri-li Ge, Haining Fan, Le Guo & Feng Tang. (2022) Production and Evaluation of a Novel Multi-Epitope Bivalent Vaccine Against Echinococcus multilocaularis Metacestode. International Journal of Peptide Research and Therapeutics 28:4.
Crossref
Md Abdus Subhan & Mohammed Muzibur Rahman. (2022) Recent Development in Metallic Nanoparticles for Breast Cancer Therapy and Diagnosis. The Chemical Record 22:7.
Crossref
Hui Jing Yu, Eva Thijssen, Emilie van Brummelen, Johan L. van der Plas, Igor Radanovic, Matthijs Moerland, Eric Hsieh, Geert Jan Groeneveld & Jean‐Cosme Dodart. (2022) A Randomized First‐in‐Human Study With UB‐312, a UBITh® α‐Synuclein Peptide Vaccine. Movement Disorders 37:7, pages 1416-1424.
Crossref
Navya Bellamkonda, Upendra Pradeep Lambe, Sonali Sawant, Shyam Sundar Nandi, Chiranjib Chakraborty & Deepak Shukla. (2022) Immune Response to SARS-CoV-2 Vaccines. Biomedicines 10:7, pages 1464.
Crossref
Jenny E. Hernandez-Davies, Emmanuel P. Dollinger, Egest J. Pone, Jiin Felgner, Li Liang, Shirin Strohmeier, Sharon Jan, Tyler J. Albin, Aarti Jain, Rie Nakajima, Algimantas Jasinskas, Florian Krammer, Aaron Esser-Kahn, Philip L. Felgner, Qing Nie & D. Huw Davies. (2022) Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants. Scientific Reports 12:1.
Crossref
Sneha Ratnapriya, Eva Perez‐Greene, Luca Schifanella & Alon Herschhorn. (2021) Adjuvant‐mediated enhancement of the immune response to HIV vaccines. The FEBS Journal 289:12, pages 3317-3334.
Crossref
Peiru Chen, Dali Wang, Yuyan Wang, Lei Zhang, Qiwei Wang, Lanxia Liu, Jiahe Li, Xin Sun, Mengqi Ren, Ruoxuan Wang, Yang Fang, Jean J. Zhao & Ke Zhang. (2022) Maximizing TLR9 Activation in Cancer Immunotherapy with Dual-Adjuvanted Spherical Nucleic Acids. Nano Letters 22:10, pages 4058-4066.
Crossref
Shugang Qin, Xiaoshan Tang, Yuting Chen, Kepan Chen, Na Fan, Wen Xiao, Qian Zheng, Guohong Li, Yuqing Teng, Min Wu & Xiangrong Song. (2022) mRNA-based therapeutics: powerful and versatile tools to combat diseases. Signal Transduction and Targeted Therapy 7:1.
Crossref
Suraj Toraskar, Preeti Madhukar Chaudhary & Raghavendra Kikkeri. (2022) The Shape of Nanostructures Encodes Immunomodulation of Carbohydrate Antigen and Vaccine Development. ACS Chemical Biology 17:5, pages 1122-1130.
Crossref
Yiwen Zhao, Zhuofan Li, Jewel Voyer, Yibo Li & Xinyuan Chen. (2022) Flagellin/Virus-like Particle Hybrid Platform with High Immunogenicity, Safety, and Versatility for Vaccine Development. ACS Applied Materials & Interfaces 14:19, pages 21872-21885.
Crossref
Khue G. Nguyen, Siena M. Mantooth, Maura R. Vrabel & David A. Zaharoff. (2022) Intranasal Delivery of Thermostable Subunit Vaccine for Cross-Reactive Mucosal and Systemic Antibody Responses Against SARS-CoV-2. Frontiers in Immunology 13.
Crossref
Jing Sui, Wenliang Qiao, Xinrong Xiang & Youfu Luo. (2022) Epigenetic changes in Mycobacterium tuberculosis and its host provide potential targets or biomarkers for drug discovery and clinical diagnosis. Pharmacological Research 179, pages 106195.
Crossref
Mohammed Ali Dahhas & Mohammad A. Alsenaidy. (2022) Role of site-directed mutagenesis and adjuvants in the stability and potency of anthrax protective antigen. Saudi Pharmaceutical Journal 30:5, pages 595-604.
Crossref
YiTing Bai, TianRan Wang, SongLing Zhang, XueSi Chen & ChaoLiang He. (2022) Recent advances in organic and polymeric carriers for local tumor chemo-immunotherapy. Science China Technological Sciences 65:5, pages 1011-1028.
Crossref
Junli Meng, Peisen Zhang, Qizhe Chen, Zihua Wang, Yuan Gu, Jie Ma, Wang Li, Chen Yang, Yuanyuan Qiao, Yi Hou, Lihong Jing, Yong Wang, Zi Gu, Lichong Zhu, Haozhen Xu, Xueguang Lu & Mingyuan Gao. (2022) Two‐Pronged Intracellular Co‐Delivery of Antigen and Adjuvant for Synergistic Cancer Immunotherapy. Advanced Materials 34:21.
Crossref
Edio Maldonado, Sebastian Morales-Pison, Fabiola Urbina & Aldo Solari. (2022) Vaccine Design against Chagas Disease Focused on the Use of Nucleic Acids. Vaccines 10:4, pages 587.
Crossref
Longchao Liu, Jiahui Chen, Hongyi Zhang, Jianfeng Ye, Casey Moore, Changzheng Lu, Yan Fang, Yang-Xin Fu & Bo Li. (2022) Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity. Nature Cancer 3:4, pages 437-452.
Crossref
Ranmali Kavishna, Tha Yang Kang, Maurizio Vacca, Benson Yen Leong Chua, Hae-Young Park, Peck Szee Tan, Vincent TK Chow, Mireille H Lahoud & Sylvie Alonso. (2022) A single-shot vaccine approach for the universal influenza A vaccine candidate M2e. Proceedings of the National Academy of Sciences 119:13.
Crossref
Hermann Unger, Richard T. Kangethe, Fatima Liaqat & Gerrit J. Viljoen. (2022) Advances in Irradiated Livestock Vaccine Research and Production Addressing the Unmet Needs for Farmers and Veterinary Services in FAO/IAEA Member States. Frontiers in Immunology 13.
Crossref
Yifeng Qin, Qingyuan Teng, Delan Feng, Yu Pei, Ye Zhao & Guozhong Zhang. (2022) Development of a Nanoparticle Multiepitope DNA Vaccine against Virulent Infectious Bronchitis Virus Challenge. The Journal of Immunology 208:6, pages 1396-1405.
Crossref
Qingfu Zhao, Yunhao Wang, Binyu Zhao, Hengkai Chen, Zhixiong Cai, Youshi Zheng, Yongyi Zeng, Da Zhang & Xiaolong Liu. (2022) Neoantigen Immunotherapeutic-Gel Combined with TIM-3 Blockade Effectively Restrains Orthotopic Hepatocellular Carcinoma Progression. Nano Letters 22:5, pages 2048-2058.
Crossref
Irina Ushach, Ren Zhu, Elen Rosler, Rajendra K. Pandey, N. Tilani S. De Costa, Soheil Pourshahian, Qinglin Han, Chris Li, Leonid Beigelman, Sergei M. Gryaznov & Theodore Yun. (2022) Targeting TLR9 agonists to secondary lymphoid organs induces potent immune responses against HBV infection. Molecular Therapy - Nucleic Acids 27, pages 1103-1115.
Crossref
Husun Qian, Ting Zhou, Yixin Fu, Minkang Guo, Wu Yang, Dian Zhang, Wenli Fang, Mengli Yao, He Shi, Chengsen Chai, Wei Cheng, Shijia Ding & Tingmei Chen. (2022) Self-assembled tetrahedral framework nucleic acid mediates tumor-associated macrophage reprogramming and restores antitumor immunity. Molecular Therapy - Nucleic Acids 27, pages 763-773.
Crossref
Garrett Kelly, Joshua J. Milligan, Eric M. Mastria, Sarah Kim, Stephanie R. Zelenetz, Jarrett Dobbins, Leon Y. Cai, Xinghai Li, Smita K. Nair & Ashutosh Chilkoti. (2022) Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot. Journal of Controlled Release 343, pages 267-276.
Crossref
Gracia Gracia, Enyuan Cao, Ruby Kochappan, Christopher J.H. Porter, Angus P.R. Johnston & Natalie L. Trevaskis. (2022) Association of a vaccine adjuvant with endogenous HDL increases lymph uptake and dendritic cell activation. European Journal of Pharmaceutics and Biopharmaceutics 172, pages 240-252.
Crossref
Mahadi Hasan, Anowara Khatun & Kentaro Kogure. (2022) Iontophoresis of Biological Macromolecular Drugs. Pharmaceutics 14:3, pages 525.
Crossref
Hirokazu Okada, Ken Takahashi, Hiroaki Yaku, Kouji Kobiyama, Keiko Iwaisako, Xiangdong Zhao, Masahiro Shiokawa, Norimitsu Uza, Yuzo Kodama, Ken J. Ishii & Hiroshi Seno. (2022) In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy. Scientific Reports 12:1.
Crossref
Anh Thi Tram Tu, Kazuaki Hoshi, Miwako Shobo & Tomohiko Yamazaki. (2022) G-quadruplex-based CpG oligodeoxynucleotide/DOTAP complex strongly stimulates immunity in CpG motif-specific and loop-length-dependent manners. Nanomedicine: Nanotechnology, Biology and Medicine 40, pages 102508.
Crossref
Krystyna Cwiklinski, Orla Drysdale, Jesús López Corrales, Yolanda Corripio-Miyar, Carolina De Marco Verissimo, Heather Jewhurst, David Smith, Richard Lalor, Tom N. McNeilly & John P. Dalton. (2022) Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth Fasciola hepatica. Vaccines 10:2, pages 155.
Crossref
Thomas M. Aune, John T. Tossberg, Rachel M. Heinrich, Krislyn P. Porter & Philip S. CrookeIIIIII. (2022) Alu RNA Structural Features Modulate Immune Cell Activation and A-to-I Editing of Alu RNAs Is Diminished in Human Inflammatory Bowel Disease. Frontiers in Immunology 13.
Crossref
Zhiang Liu, Yunfan Yang, ChenChen Meng, Meihua Fan, Jing Guo, Jie Li, Zepeng Jing, Pingping Wang, Ruipeng Li, Zhiwei Feng, Feng Ren, Mingyong Wang & Tiesuo Zhao. (2021) A novel polypeptide vaccine and adjuvant formulation of EV71. Pathogens and Disease 79:9.
Crossref
Siddesh V. Hartimath, Boominathan Ramasamy, Tan Yun Xuan, Tang Jun Rong, Shivashankar Khanapur, Peter Cheng, You Yi Hwang, Edward G. Robins & Julian L. Goggi. (2022) Granzyme B PET Imaging in Response to In Situ Vaccine Therapy Combined with αPD1 in a Murine Colon Cancer Model. Pharmaceutics 14:1, pages 150.
Crossref
Yang Hao, Chih Kit Chung, Zhenfeng Yu, Ruben V. Huis in ‘t Veld, Ferry A. Ossendorp, Peter ten Dijke & Luis J. Cruz. (2022) Combinatorial Therapeutic Approaches with Nanomaterial-Based Photodynamic Cancer Therapy. Pharmaceutics 14:1, pages 120.
Crossref
Nastaran Barati, Amin Reza Nikpoor, Fatemeh Mosaffa, Atefeh Razazan, Ali Badiee, Seyed Mousa Motavallihaghi, Javad Behravan & Mahmoud Reza Jaafari. (2022) AE36 HER2/neu-derived peptide linked to positively charged liposomes with CpG-ODN as an effective therapeutic and prophylactic vaccine for breast cancer. Journal of Drug Delivery Science and Technology 67, pages 102904.
Crossref
Amrita Talukdar, Amal Chandra Kataki, Shripad Banavali & Jaya Ghosh. 2022. Fundamentals in Gynaecologic Malignancy. Fundamentals in Gynaecologic Malignancy 37 46 .
Bassel Akache, Felicity C. Stark, Gerard Agbayani, Tyler M. Renner & Michael J. McCluskie. 2022. Vaccine Design. Vaccine Design 179 231 .
Farrhana Ziana Firdaus, Mariusz Skwarczynski & Istvan Toth. 2022. Vaccine Design. Vaccine Design 145 178 .
Rafał Jastrząb, Damian Graczyk & Pawel Siedlecki. (2021) Molecular and Cellular Mechanisms Influenced by Postbiotics. International Journal of Molecular Sciences 22:24, pages 13475.
Crossref
Jeremy Baldwin, Sakshi Piplani, Isaac G Sakala, Yoshikazu Honda-Okubo, Lei Li & Nikolai Petrovsky. (2021) Rapid development of analytical methods for evaluating pandemic vaccines: a COVID-19 perspective. Bioanalysis 13:24, pages 1805-1826.
Crossref
S. Ribes, L. Zacke, S. Nessler, N. Saiepour, E. Avendaño-Guzmán, M. Ballüer, U. K. Hanisch & R. Nau. (2021) Oligodeoxynucleotides containing unmethylated cytosine-guanine motifs are effective immunostimulants against pneumococcal meningitis in the immunocompetent and neutropenic host. Journal of Neuroinflammation 18:1.
Crossref
Anastas PashovThomas Kieber-Emmons. (2021) Will a B1.1.1.529 Vaccine Be Undermined by Antigenic Sin: An Idiotypy Inspired Workaround. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 40:6, pages 237-238.
Crossref
Yanhua Li, Xiaohan Liu, Xia Zhang, Wei Pan, Na Li & Bo Tang. (2021) Immune Cycle‐Based Strategies for Cancer Immunotherapy. Advanced Functional Materials 31:50.
Crossref
Jianfeng Hua, Pan Wu, Lu Gan, Zhikun Zhang, Jian He, Liping Zhong, Yongxiang Zhao & Yong Huang. (2021) Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy. Frontiers in Oncology 11.
Crossref
Haiyue Xu, Lucy Cai, Stephanie Hufnagel & Zhengrong Cui. (2021) Intranasal vaccine: Factors to consider in research and development. International Journal of Pharmaceutics 609, pages 121180.
Crossref
Jianling Wang, Lihua Sui, Jia Huang, Lu Miao, Yubing Nie, Kuansong Wang, Zhichun Yang, Qiong Huang, Xue Gong, Yayun Nan & Kelong Ai. (2021) MoS2-based nanocomposites for cancer diagnosis and therapy. Bioactive Materials 6:11, pages 4209-4242.
Crossref
Tadech Boonpiyathad, Mongkol Lao-Araya, Chirawat Chiewchalermsri, Sasipa Sangkanjanavanich & Hideaki Morita. (2021) Allergic Rhinitis: What Do We Know About Allergen-Specific Immunotherapy?. Frontiers in Allergy 2.
Crossref
Brett H. Pogostin & Kevin J. McHugh. (2021) Novel Vaccine Adjuvants as Key Tools for Improving Pandemic Preparedness. Bioengineering 8:11, pages 155.
Crossref
Nilüfer GÜN. (2021) Brief overview of anthrax vaccines: Current and future developments. International Journal of Life Sciences and Biotechnology.
Crossref
Zehua Zhou, Xinyu Zhang, Qianqian Li, Lili Fu, Meiyu Wang, Shuo Liu, Jiajing Wu, Jianhui Nie, Li Zhang, Chenyan Zhao, Fei Jiang, Yimeng An, Bin Yu, Haifa Zheng, Youchun Wang, Aihua Zhao & Weijin Huang. (2021) Unmethylated CpG motif-containing genomic DNA fragments of bacillus calmette-guerin improves immune response towards a DNA vaccine for COVID-19. Vaccine 39:41, pages 6050-6056.
Crossref
Waleed H. Mahallawi & Talal M. Aljeraisi. (2021) Infection with SARS-CoV-2 primes immunological memory in human nasal-associated lymphoid tissue. Clinical Immunology 231, pages 108850.
Crossref
Haejoo Kim, Wei Zhang, Juyoung Hwang, Eun-Koung An, Yeol Kyo Choi, Eunyoung Moon, Mark Loznik, Yang Hoon Huh, Andreas Herrmann, Minseok Kwak & Jun-O Jin. (2021) Carrier-free micellar CpG interacting with cell membrane for enhanced immunological treatment of HIV-1. Biomaterials 277, pages 121081.
Crossref
Yue Yin, Wen Su, Jie Zhang, Wenping Huang, Xiaoyang Li, Haixia Ma, Mixiao Tan, Haohao Song, Guoliang Cao, Shengji Yu, Di Yu, Ji Hoon Jeong, Xiao Zhao, Hui Li, Guangjun Nie & Hai Wang. (2021) Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19. ACS Nano 15:9, pages 14347-14359.
Crossref
Logan R. Wilks, Gaurav Joshi, Megan R. Grisham & Harvinder Singh Gill. (2021) Tyrosine-Based Cross-Linking of Peptide Antigens to Generate Nanoclusters with Enhanced Immunogenicity: Demonstration Using the Conserved M2e Peptide of Influenza A. ACS Infectious Diseases 7:9, pages 2723-2735.
Crossref
Jacqui Taryn Nimmo, Louise Kelly, Ajay Verma, Roxana O. Carare, James A. R. Nicoll & Jean-Cosme Dodart. (2021) Amyloid-β and α-Synuclein Immunotherapy: From Experimental Studies to Clinical Trials. Frontiers in Neuroscience 15.
Crossref
Muhammet Karakavuk, Hüseyin Can, Aytül Gül, Aysu Değirmenci Döşkaya, Sedef Erkunt Alak, Cemal Ün, Adnan Yüksel Gürüz & Mert Döşkaya. (2021) GRA8 DNA vaccine formulations protect against chronic toxoplasmosis. Microbial Pathogenesis 158, pages 105016.
Crossref
Zhenchuan Wu & Keqin Liu. (2021) Overview of vaccine adjuvants. Medicine in Drug Discovery 11, pages 100103.
Crossref
Yuqian Zhang, Guofang Zhang, Guocheng Wang, Lidong Wu, Nancy A. Monteiro‐Riviere & Yang Li. (2021) The synergistic strategies for the immuno‐oncotherapy with photothermal nanoagents . WIREs Nanomedicine and Nanobiotechnology 13:5.
Crossref
Gregory P. Howard, Nicole G. Bender, Prachi Khare, Borja López-Gutiérrez, Vincent Nyasembe, William J. Weiss, Jerry W. Simecka, Timothy Hamerly, Hai-Quan Mao & Rhoel R. Dinglasan. (2021) Immunopotentiation by Lymph-Node Targeting of a Malaria Transmission-Blocking Nanovaccine. Frontiers in Immunology 12.
Crossref
Sakineh Pirahmadi, Sedigheh Zakeri, Navid D. Djadid & Akram A. Mehrizi. (2021) A review of combination adjuvants for malaria vaccines: a promising approach for vaccine development. International Journal for Parasitology 51:9, pages 699-717.
Crossref
Worapol Ngamcherdtrakul, Moataz Reda, Molly A. Nelson, Ruijie Wang, Husam Y. Zaidan, Daniel S. Bejan, Ngoc Ha Hoang, Ryan S. Lane, Shiuh‐Wen Luoh, Sancy A. Leachman, Gordon B. Mills, Joe W. Gray, Amanda W. Lund & Wassana Yantasee. (2021) In Situ Tumor Vaccination with Nanoparticle Co‐Delivering CpG and STAT3 siRNA to Effectively Induce Whole‐Body Antitumor Immune Response. Advanced Materials 33:31.
Crossref
Ole A. W. Haabeth, Julian J. K. Lohmeyer, Adrienne Sallets, Timothy R. Blake, Idit Sagiv-Barfi, Debra K. Czerwinski, Blaine McCarthy, Abigail E. Powell, Paul A. Wender, Robert M. Waymouth & Ronald Levy. (2021) An mRNA SARS-CoV-2 Vaccine Employing Charge-Altering Releasable Transporters with a TLR-9 Agonist Induces Neutralizing Antibodies and T Cell Memory. ACS Central Science 7:7, pages 1191-1204.
Crossref
Rekha R. Rapaka, Alan S. Cross & Monica A. McArthur. (2021) Using Adjuvants to Drive T Cell Responses for Next-Generation Infectious Disease Vaccines. Vaccines 9:8, pages 820.
Crossref
Cathy Leonard, Guillem Montamat, Caroline Davril, Olivia Domingues, Oliver Hunewald, Dominique Revets, Coralie Guerin, Simon Blank, Justine Heckendorn, Gauthier Jardon, François Hentges & Markus Ollert. (2021) Comprehensive mapping of immune tolerance yields a regulatory TNF receptor 2 signature in a murine model of successful Fel d 1‐specific immunotherapy using high‐dose CpG adjuvant. Allergy 76:7, pages 2153-2165.
Crossref
Dennis McGonagle, Gabriele De Marco & Charles Bridgewood. (2021) Mechanisms of Immunothrombosis in Vaccine-Induced Thrombotic Thrombocytopenia (VITT) Compared to Natural SARS-CoV-2 Infection. Journal of Autoimmunity 121, pages 102662.
Crossref
Christian Bode, Jens M. Poth, Mario Fox, Susanne Schulz, Dennis M. Klinman, Eicke Latz & Folkert Steinhagen. (2021) Cytosolic d ‐type CpG‐oligonucleotides induce a type I interferon response by activating the cGAS‐STING signaling pathway . European Journal of Immunology 51:7, pages 1686-1697.
Crossref

Displaying 200 of 575 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.