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Expert Review of Vaccines Volume 10, 2011 - Issue 11
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Review

Developments in virus-like particle-based vaccines for infectious diseases and cancer

Luigi Buonaguro Molecular Biology and Viral Oncology, Department of Experimental Oncology, Istituto Nazionale Tumori Fond Pascale, Via Mariano Semmola 142, 80131 Napoli, Italy;[email protected]
,
Maria Tagliamonte Molecular Biology and Viral Oncology, Department of Experimental Oncology, Istituto Nazionale Tumori Fond Pascale, Via Mariano Semmola 142, 80131 Napoli, Italy; Molecular Biology and Viral Oncology, Department of Experimental Oncology, Istituto Nazionale Tumori Fond Pascale, Via Mariano Semmola 142, 80131 Napoli, Italy
,
Maria Lina Tornesello Molecular Biology and Viral Oncology, Department of Experimental Oncology, Istituto Nazionale Tumori Fond Pascale, Via Mariano Semmola 142, 80131 Napoli, Italy; Molecular Biology and Viral Oncology, Department of Experimental Oncology, Istituto Nazionale Tumori Fond Pascale, Via Mariano Semmola 142, 80131 Napoli, Italy
&
Franco M Buonaguro Molecular Biology and Viral Oncology, Department of Experimental Oncology, Istituto Nazionale Tumori Fond Pascale, Via Mariano Semmola 142, 80131 Napoli, Italy; Molecular Biology and Viral Oncology, Department of Experimental Oncology, Istituto Nazionale Tumori Fond Pascale, Via Mariano Semmola 142, 80131 Napoli, Italy
Pages 1569-1583 | Published online: 09 Jan 2014

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Tehila Mayer-Sonnenfeld, Michael Har-Noy, Kevin O. Lillehei & Michael W. Graner. (2013) Proteomic analyses of different human tumour-derived chaperone-rich cell lysate (CRCL) anti-cancer vaccines reveal antigen content and strong similarities amongst the vaccines along with a basis for CRCL's unique structure: CRCL vaccine proteome leads to unique structure. International Journal of Hyperthermia 29:6, pages 520-527.
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Christian Moser, Matthias Müller, Matthias D Kaeser, Ulrike Weydemann & Mario Amacker. (2013) Influenza virosomes as vaccine adjuvant and carrier system. Expert Review of Vaccines 12:7, pages 779-791.
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Masaaki Kawano, Masanori Matsui & Hiroshi Handa. (2013) SV40 virus-like particles as an effective delivery system and its application to a vaccine carrier. Expert Review of Vaccines 12:2, pages 199-210.
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Nunzia Scotti & Edward P Rybicki. (2013) Virus-like particles produced in plants as potential vaccines. Expert Review of Vaccines 12:2, pages 211-224.
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Andrew J Pollard & Lauren Constable. (2011) Expert Review of Vaccines 10-year anniversary issue. Expert Review of Vaccines 10:11, pages 1489-1491.
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Charles B Chesson & Andrew Zloza. (2017) Nanoparticles: augmenting tumor antigen presentation for vaccine and immunotherapy treatments of cancer. Nanomedicine 12:23, pages 2693-2706.
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Derrick P. McCarthy, Zoe N. Hunter, Bryce Chackerian, Lonnie D. Shea & Stephen D. Miller. (2014) Targeted immunomodulation using antigen-conjugated nanoparticles. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 6:3, pages 298-315.
Crossref
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Anastasia Lanzi, Cynthia M. Fehres, Tanja D. de Gruijl, Yvette van Kooyk & Enrico Mastrobattista. (2013) Effects of Antigen-Expressing Immunostimulatory Liposomes on Chemotaxis and Maturation of Dendritic Cells In Vitro and in Human Skin Explants. Pharmaceutical Research 31:2, pages 516-526.
Crossref
Franco M Buonaguro & Luigi BuonaguroMasaaki KawanoMasanori MatsuiHiroshi Handa. 2014. Virus-like Particles in Vaccine Development. Virus-like Particles in Vaccine Development 86 100 .
Franco M Buonaguro & Luigi BuonaguroNunzia ScottiEdward P Rybicki. 2014. Virus-like Particles in Vaccine Development. Virus-like Particles in Vaccine Development 102 118 .
Abhishek Singharoy, Abhigna Polavarapu, Harshad Joshi, Mu-Hyun Baik & Peter Ortoleva. (2013) Epitope Fluctuations in the Human Papillomavirus Are Under Dynamic Allosteric Control: A Computational Evaluation of a New Vaccine Design Strategy. Journal of the American Chemical Society 135:49, pages 18458-18468.
Crossref
Douglas M. Smith, Jakub K. Simon & James R. Baker Jr. (2013) Applications of nanotechnology for immunology. Nature Reviews Immunology 13:8, pages 592-605.
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Fuxiao Liu, Xiaodong Wu, Lin Li, Zengshan Liu & Zhiliang Wang. (2013) Use of baculovirus expression system for generation of virus-like particles: Successes and challenges. Protein Expression and Purification 90:2, pages 104-116.
Crossref
T Jake Liang. (2013) Current progress in development of hepatitis C virus vaccines. Nature Medicine 19:7, pages 869-878.
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Geraldine LescailleFabien PitoisetRodney MacedoClaude BaillouChristophe HuretDavid KlatzmannEric TartourFrançois M. LemoineBertrand Bellier. (2013) Efficacy of DNA Vaccines Forming E7 Recombinant Retroviral Virus-Like Particles for the Treatment of Human Papillomavirus-Induced Cancers. Human Gene Therapy 24:5, pages 533-544.
Crossref
Jessica M. Moffat, Wan-Shoo Cheong, José A. Villadangos, Justine D. Mintern & Hans J. Netter. (2013) Hepatitis B virus-like particles access major histocompatibility class I and II antigen presentation pathways in primary dendritic cells. Vaccine 31:18, pages 2310-2316.
Crossref
John A. Robinson. (2013) Max Bergmann lecture Protein epitope mimetics in the age of structural vaccinology. Journal of Peptide Science 19:3, pages 127-140.
Crossref
Juan Bárcena & Esther Blanco. 2013. Structure and Physics of Viruses. Structure and Physics of Viruses 631 665 .
John T. Schiller & Douglas R. Lowy. (2012) Understanding and learning from the success of prophylactic human papillomavirus vaccines. Nature Reviews Microbiology 10:10, pages 681-692.
Crossref
Luigi Buonaguro, Maria Tagliamonte, Maria Luisa Visciano, Hanne Andersen, Mark Lewis, Ranajit Pal, Maria Lina Tornesello, Ulf Schroeder, Jorma Hinkula, Britta Wahren & Franco M. Buonaguro. (2012) Immunogenicity of HIV Virus-Like Particles in Rhesus Macaques by Intranasal Administration. Clinical and Vaccine Immunology 19:6, pages 970-973.
Crossref
Joseph G. Altin. 2012. Innovation in Vaccinology. Innovation in Vaccinology 135 178 .

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