1,329
Views
97
CrossRef citations to date
0
Altmetric
Review

Insect cell technology is a versatile and robust vaccine manufacturing platform

&
Pages 1063-1081 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Lilí Esmeralda Gallo–Ramírez, Alexander Nikolay, Yvonne Genzel & Udo Reichl. (2015) Bioreactor concepts for cell culture-based viral vaccine production. Expert Review of Vaccines 14:9, pages 1181-1195.
Read now
Hongjing Gu, Tieling Li, Lina Han, Ping Zhu, Peirui Zhang, Shaogeng Zhang, Sujing Sun, Yueqiang Duan, Li Xing, Zhongpeng Zhao, Chengcai Lai, Bohai Wen, Xiliang Wang & PengHui Yang. (2015) Protection conferred by virus-like particle vaccines against respiratory syncytial virus infection in mice by intranasal vaccination . Human Vaccines & Immunotherapeutics 11:4, pages 1057-1064.
Read now
Shih-Yeh Lin, Yao-Chi Chung & Yu-Chen Hu. (2014) Update on baculovirus as an expression and/or delivery vehicle for vaccine antigens. Expert Review of Vaccines 13:12, pages 1501-1521.
Read now
Tanja K Kiener, Balraj Premanand & Jimmy Kwang. (2013) Immune responses to baculovirus-displayed enterovirus 71 VP1 antigen. Expert Review of Vaccines 12:4, pages 357-364.
Read now
Martine Cérutti & Josée Golay. (2012) Lepidopteran cells, an alternative for the production of recombinant antibodies?. mAbs 4:3, pages 294-309.
Read now
Darius Ghaderi, Mai Zhang, Nancy Hurtado-Ziola & Ajit Varki. (2012) Production platforms for biotherapeutic glycoproteins. Occurrence, impact, and challenges of non-human sialylation. Biotechnology and Genetic Engineering Reviews 28:1, pages 147-176.
Read now

Articles from other publishers (91)

Ping Y. Lye, Eiji Kotani & Mervyn W.O. Liew. (2023) Progress and challenges in production of recombinant Newcastle disease virus hemagglutinin-neuraminidase subunit vaccine. Process Biochemistry 132, pages 263-277.
Crossref
Jabez Raju Battu, Karthik Somala, Yashaswini Gummudala, Shankara Sai Reddy Morthala, Karthik Ramappa, Anil Gadde & Nitika Negi. (2023) Insect cell culture vis-à-vis insect pest control. Egyptian Journal of Biological Pest Control 33:1.
Crossref
Yoshikazu Honda-Okubo, Isaac G. Sakala, Greiciely André, E. Bart Tarbet, Brett L. Hurst & Nikolai Petrovsky. (2023) An Advax-CpG55.2 adjuvanted recombinant hemagglutinin vaccine provides immunity against H7N9 influenza in adult and neonatal mice. Vaccine 41:38, pages 5592-5602.
Crossref
Karina Klafke, Marcio Martinello Sanches, William Sihler, Marlinda Lobo de Souza & Aldo Tonso. (2023) Bioreactor Production Process of Spodoptera frugiperda multiple nucleopolyhedrovirus Biopesticide. Pathogens 12:8, pages 1001.
Crossref
Qiaonan Hong, Jian Liu, Yuquan Wei & Xiawei Wei. (2023) Application of Baculovirus Expression Vector System (BEVS) in Vaccine Development. Vaccines 11:7, pages 1218.
Crossref
Ahmad Mohammad Allam, Mohamed Karam Elbayoumy & Alaa Abdelmoneam Ghazy. (2023) Perspective vaccines for emerging viral diseases in farm animals. Clinical and Experimental Vaccine Research 12:3, pages 179.
Crossref
Steven Reid, Henry de Malmanche, Leslie Chan, Holly Popham & Monique M. van Oers. 2023. Mass Production of Beneficial Organisms. Mass Production of Beneficial Organisms 375 406 .
Deepika Divya Kadiri, P. Swarnalatha & Sujatha Peela. 2023. Introduction to Insect Biotechnology. Introduction to Insect Biotechnology 117 134 .
Jin Luo, Huan Qin, Lei Lei, Wange Lou, Ruitong Li & Zishu Pan. (2022) Virus-like particles containing a prefusion-stabilized F protein induce a balanced immune response and confer protection against respiratory syncytial virus infection in mice. Frontiers in Immunology 13.
Crossref
Jacob A. Corcoran & Xu Han. (2022) Improved cryopreservation media formulation reduces costs of maintenance while preserving function of genetically modified insect cells. In Vitro Cellular & Developmental Biology - Animal 58:10, pages 867-876.
Crossref
Ricardo Correia, Bárbara Fernandes, Rute Castro, Hikaru Nagaoka, Eizo Takashima, Takafumi Tsuboi, Akihisa Fukushima, Nicola K. Viebig, Hilde Depraetere, Paula M. Alves & António Roldão. (2022) Asexual Blood-Stage Malaria Vaccine Candidate PfRipr5: Enhanced Production in Insect Cells. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Lukas Käßer, Maximilian Rotter, Luca Coletta, Denise Salzig & Peter Czermak. (2022) Process intensification for the continuous production of an antimicrobial peptide in stably-transformed Sf-9 insect cells. Scientific Reports 12:1.
Crossref
Jiao Hu, Qi Zhang, Peipei Peng, Rumeng Li, Jun Li, Xiaoquan Wang, Min Gu, Zenglei Hu, Shunlin Hu, Xiaowen Liu, Mei Mei, Xinan Jiao, Daxin Peng & Xiufan Liu. (2022) Baculovirus-derived influenza virus-like particle confers complete protection against lethal H7N9 avian influenza virus challenge in chickens and mice. Veterinary Microbiology 264, pages 109306.
Crossref
H. B. Ranjitha, Madhu Ramesh, Subhasmita Behera, Dhanesh ValiyaValappil, Suresh H. Basagoudanavar & Anjum Sherasiya. 2022. Sustainable Agriculture Reviews 57. Sustainable Agriculture Reviews 57 175 207 .
Ebrahim Kord, Farzin Roohvand, Jean Dubuisson, Thibaut Vausselin, Hosein Nasr Azadani, Abolfazl Keshavarz, Ahmad Nejati & Katayoun Samimi-Rad. (2021) BacMam virus-based surface display for HCV E2 glycoprotein induces strong cross-neutralizing antibodies and cellular immune responses in vaccinated mice. Infectious Agents and Cancer 16:1.
Crossref
Jiao Hu, Peipei Peng, Jun Li, Qi Zhang, Rumeng Li, Xiaoquan Wang, Min Gu, Zenglei Hu, Shunlin Hu, Xiaowen Liu, Xinan Jiao, Daxin Peng & Xiufan Liu. (2021) Single Dose of Bivalent H5 and H7 Influenza Virus-Like Particle Protects Chickens Against Highly Pathogenic H5N1 and H7N9 Avian Influenza Viruses. Frontiers in Veterinary Science 8.
Crossref
Sk Mohiuddin Choudhury, XuSheng Ma, Wen Dang, YuanYuan Li & HaiXue Zheng. (2021) Recent Development of Ruminant Vaccine Against Viral Diseases. Frontiers in Veterinary Science 8.
Crossref
Raquel Cid & Jorge Bolívar. (2021) Platforms for Production of Protein-Based Vaccines: From Classical to Next-Generation Strategies. Biomolecules 11:8, pages 1072.
Crossref
Aiping Wang, Jinran Du, Hua Feng, Jingming Zhou, Yumei Chen, Yankai Liu, Min Jiang, Rui Jia, Yuanyuan Tian & Gaiping Zhang. (2021) Identification of a novel bluetongue virus 1 specific B cell epitope using monoclonal antibodies against the VP2 protein. International Journal of Biological Macromolecules 183, pages 1393-1401.
Crossref
Eduard Puente‐Massaguer, Paula Grau‐Garcia, Florian Strobl, Reingard Grabherr, Gerald Striedner, Martí Lecina & Francesc Gòdia. (2020) Accelerating HIV‐1 VLP production using stable High Five insect cell pools. Biotechnology Journal 16:4.
Crossref
Pranav R.H. Joshi, Alina Venereo‐Sanchez, Parminder S. Chahal & Amine A. Kamen. (2021) Advancements in molecular design and bioprocessing of recombinant adeno‐associated virus gene delivery vectors using the insect‐cell baculovirus expression platform. Biotechnology Journal 16:4.
Crossref
Teshome Mebatsion. 2021. Viral Vectors in Veterinary Vaccine Development. Viral Vectors in Veterinary Vaccine Development 3 12 .
Friederike Eilts, Julie Harnischfeger, Daniel Loewe, Michael W. Wolff, Denise Salzig & Peter Czermak. 2021. Vaccine Delivery Technology. Vaccine Delivery Technology 367 390 .
Nathaniel Nyakaat Ninyio, Kok Lian Ho, Abdul Rahman Omar, Wen Siang Tan, Munir Iqbal & Abdul Razak Mariatulqabtiah. (2020) Virus-like Particle Vaccines: A Prospective Panacea Against an Avian Influenza Panzootic. Vaccines 8:4, pages 694.
Crossref
Hongchao Wu, Hongli Jin, Lingxiao Wang, Ningning Huo, Di Liu, Hangtian Ding, Yujiao Cao, Caihong Liu, Xiangfeng Xi, Cuicui Jiao, Norman Spibey, Jing Shi, Yuxiu Liu & Kegong Tian. (2020) Generation and immunogenicity of virus-like particles based on mink enteritis virus capsid protein VP2 expressed in Sf9 cells. Archives of Virology 165:9, pages 2065-2071.
Crossref
Mario Fragoso‐Saavedra & Marco A. Vega‐López. (2020) Induction of mucosal immunity against pathogens by using recombinant baculoviral vectors: Mechanisms, advantages, and limitations. Journal of Leukocyte Biology 108:3, pages 835-850.
Crossref
Eduard Puente-Massaguer, Florian Strobl, Reingard Grabherr, Gerald Striedner, Martí Lecina & Francesc Gòdia. (2020) PEI-Mediated Transient Transfection of High Five Cells at Bioreactor Scale for HIV-1 VLP Production. Nanomaterials 10:8, pages 1580.
Crossref
Lin Zhou, Yunfei Li, Heyuan Wang, Yicheng Zhou & Zhihui Zhu. (2020) Establishment and characterization of a new embryonic cell line from Helicoverpa armigera (Hübner). In Vitro Cellular & Developmental Biology - Animal 56:7, pages 559-566.
Crossref
Wei-Feng Ding, Zhi-Gang Liu, Na Sun, Xin Zhang, Xian Li & Ying Feng. (2020) Screening of single-cell clonal lines from Papilio demoleus Linnaeus cell lines for exogenous protein expression and adaptation in serum-free culture. In Vitro Cellular & Developmental Biology - Animal 56:6, pages 444-451.
Crossref
Katrin Reiter, Patricia Pereira Aguilar, Dominik Grammelhofer, Judith Joseph, Petra Steppert & Alois Jungbauer. (2020) Separation of influenza virus‐like particles from baculovirus by polymer‐grafted anion exchanger. Journal of Separation Science 43:12, pages 2270-2278.
Crossref
Eduard Puente-Massaguer, Martí Lecina & Francesc Gòdia. (2020) Application of advanced quantification techniques in nanoparticle-based vaccine development with the Sf9 cell baculovirus expression system. Vaccine 38:7, pages 1849-1859.
Crossref
Vrinda M Kurup & Jaya Thomas. (2019) Edible Vaccines: Promises and Challenges. Molecular Biotechnology 62:2, pages 79-90.
Crossref
M. Laura Fabre, Paula N. Arrías, Tomás Masson, Matías L. Pidre & Víctor Romanowski. 2020. Emerging and Reemerging Viral Pathogens. Emerging and Reemerging Viral Pathogens 197 224 .
Adly M. M. Abd-Alla, Irene K. Meki & Güler Demirbas-Uzel. 2020. Cottage Industry of Biocontrol Agents and Their Applications. Cottage Industry of Biocontrol Agents and Their Applications 277 295 .
Liu, Huang, Chen, Li, Yan, Jin & Xu. (2019) Ionic Liquids Enhanced Alkynyl Schiff Bases Derivatives of Fipronil Synthesis and Their Cytotoxicity Studies. Molecules 24:18, pages 3223.
Crossref
Maren Bleckmann, Margitta Schürig, Michelle Endres, Anke Samuels, Daniela Gebauer, Nadine Konisch & Joop van den Heuvel. (2019) Identifying parameters to improve the reproducibility of transient gene expression in High Five cells. PLOS ONE 14:6, pages e0217878.
Crossref
E. Criscuolo, V. Caputo, R. A. Diotti, G. A. Sautto, G. A. Kirchenbaum & N. Clementi. (2019) Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines. Journal of Immunology Research 2019, pages 1-13.
Crossref
Jiao Hu, Yanyan Liang, Zenglei Hu, Xiaoquan Wang, Min Gu, Rumeng Li, Chunxi Ma, Xiaowen Liu, Shunlin Hu, Sujuan Chen, Daxin Peng, Xinan Jiao & Xiufan Liu. (2019) Recombinant baculovirus vaccine expressing hemagglutinin of H7N9 avian influenza virus confers full protection against lethal highly pathogenic H7N9 virus infection in chickens. Archives of Virology 164:3, pages 807-817.
Crossref
Hao Zheng, Feifei Ren, Qiuyuan Lu, Zhenming Cao, Jichen Song, Min Feng, Jisheng Liu & Jingchen Sun. (2018) An efficient method for multigene co-interference by recombinant Bombyx mori nucleopolyhedrovirus. Molecular Genetics and Genomics 294:1, pages 111-120.
Crossref
Krisztina Koczka, Wolfgang Ernst, Dieter Palmberger, Miriam Klausberger, Lisa Nika & Reingard Grabherr. (2019) Development of a Dual-Vector System Utilizing MicroRNA Mimics of the Autographa californica miR-1 for an Inducible Knockdown in Insect Cells. International Journal of Molecular Sciences 20:3, pages 533.
Crossref
Christine M. Yee, Andrew J. Zak, Brett D. Hill & Fei Wen. (2018) The Coming Age of Insect Cells for Manufacturing and Development of Protein Therapeutics. Industrial & Engineering Chemistry Research 57:31, pages 10061-10070.
Crossref
Antonio Contreras-Gómez, Alba Beas-Catena, Asterio Sánchez-Mirón, Francisco García-Camacho & Emilio Molina Grima. (2017) The use of an artificial neural network to model the infection strategy for baculovirus production in suspended insect cell cultures. Cytotechnology 70:2, pages 555-565.
Crossref
Cuitlahuac Chavez-Pena & Amine A. Kamen. (2018) RNA interference technology to improve the baculovirus-insect cell expression system. Biotechnology Advances 36:2, pages 443-451.
Crossref
Kendra H. Steele, Barbara J. Stone, Kathleen M. Franklin, Angelika Fath‐Goodin, Xiufeng Zhang, Haobo Jiang, Bruce A. Webb & Christoph Geisler. (2017) Improving the baculovirus expression vector system with vankyrin‐enhanced technology. Biotechnology Progress 33:6, pages 1496-1507.
Crossref
Manon Cox. (2017) Modern technology: The preferred biosecurity strategy?. Vaccine 35:44, pages 5949-5950.
Crossref
Quan Nguyen, Trinh TB.Tran, Leslie CL Chan, Lars K Nielsen & Steven Reid. (2016) In vitro production of baculoviruses: identifying host and virus genes associated with high productivity. Applied Microbiology and Biotechnology 100:21, pages 9239-9253.
Crossref
Marga García Durán, Sofia Costa, Javier Sarraseca, Nuria de la Roja, Julia García, Isabel García & Maria José Rodríguez. (2016) Generation of porcine reproductive and respiratory syndrome (PRRS) virus-like-particles (VLPs) with different protein composition. Journal of Virological Methods 236, pages 77-86.
Crossref
Jeffrey C. Boyington, M. Gordon Joyce, Mallika Sastry, Guillaume B. E. Stewart-Jones, Man Chen, Wing-Pui Kong, Joan O. Ngwuta, Paul V. Thomas, Yaroslav Tsybovsky, Yongping Yang, Baoshan Zhang, Lei Chen, Aliaksandr Druz, Ivelin S. Georgiev, Kiyoon Ko, Tongqing Zhou, John R. Mascola, Barney S. Graham & Peter D. Kwong. (2016) Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus. PLOS ONE 11:7, pages e0159709.
Crossref
Frank Bantleon, Sara Wolf, Henning Seismann, Svend Dam, Andrea Lorentzen, Michaela Miehe, Frederic Jabs, Thilo Jakob, Melanie Plum & Edzard Spillner. (2016) Human IgE is efficiently produced in glycosylated and biologically active form in lepidopteran cells. Molecular Immunology 72, pages 49-56.
Crossref
Hsuan Tung, Sung-Chan Wei, Huei-Ru Lo & Yu-Chan Chao. (2016) Baculovirus IE2 Stimulates the Expression of Heat Shock Proteins in Insect and Mammalian Cells to Facilitate Its Proper Functioning. PLOS ONE 11:2, pages e0148578.
Crossref
Thomas A. Kost & Christopher W. Kemp. 2016. Advanced Technologies for Protein Complex Production and Characterization. Advanced Technologies for Protein Complex Production and Characterization 187 197 .
Steven Reid, Leslie C. L. Chan, Leila Matindoost, Charlotte Pushparajan & Gabriel Visnovsky. 2016. Microbial-Based Biopesticides. Microbial-Based Biopesticides 95 117 .
Francesco Manfredi, Paola Di Bonito, Claudia Arenaccio, Simona Anticoli & Maurizio Federico. 2016. Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools. Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools 249 260 .
Leslie C. L. Chan & Steven Reid. 2016. Baculovirus and Insect Cell Expression Protocols. Baculovirus and Insect Cell Expression Protocols 161 196 .
Christine M. Thompson, Marc G. Aucoin & Amine A. Kamen. 2016. Baculovirus and Insect Cell Expression Protocols. Baculovirus and Insect Cell Expression Protocols 299 315 .
Yangkun Liu, Lei Zhang, Yuanyuan Zhang, Dandan Liu, Enqi Du & Zengqi Yang. (2015) Functional analysis of RNAi suppressor P19 on improving baculovirus yield and transgene expression in Sf9 cells. Biotechnology Letters 37:11, pages 2159-2166.
Crossref
Jamal Meghrous, Nikolai Khramtsov, Barry C. Buckland, Manon M.J. Cox, Laura A. Palomares & Indresh K. Srivastava. (2015) Dissolved carbon dioxide determines the productivity of a recombinant hemagglutinin component of an influenza vaccine produced by insect cells. Biotechnology and Bioengineering 112:11, pages 2267-2275.
Crossref
Sampath R. Kumar. (2015) Industrial production of clotting factors: Challenges of expression, and choice of host cells. Biotechnology Journal 10:7, pages 995-1004.
Crossref
Rachael S. Felberbaum. (2015) The baculovirus expression vector system: A commercial manufacturing platform for viral vaccines and gene therapy vectors. Biotechnology Journal 10:5, pages 702-714.
Crossref
Balaji Somasundaram & Linda HL Lua. (2015) Development of picornavirus-like particle vaccines. Pharmaceutical Bioprocessing 3:1, pages 45-59.
Crossref
Alex Prokhnevsky, Tarlan Mamedov, Brett Leffet, Rahila Rahimova, Ananya Ghosh, Vadim Mett & Vidadi Yusibov. (2014) Development of a Single-Replicon miniBYV Vector for Co-expression of Heterologous Proteins. Molecular Biotechnology 57:2, pages 101-110.
Crossref
Hoai T. Huynh, Trinh T.B. Tran, Leslie C.L Chan, Lars K. Nielsen & Steven Reid. (2014) Effect of the peak cell density of recombinant AcMNPV-infected Hi5 cells on baculovirus yields. Applied Microbiology and Biotechnology 99:4, pages 1687-1700.
Crossref
Laura A. Palomares, Mauricio Realpe & Octavio T. Ramírez. 2015. Animal Cell Culture. Animal Cell Culture 501 519 .
Yun-Ru Chen, Silin Zhong, Zhangjun Fei, Shan Gao, Shiying Zhang, Zhaofei Li, Ping Wang & Gary W. Blissard. (2014) Transcriptome Responses of the Host Trichoplusia ni to Infection by the Baculovirus Autographa californica Multiple Nucleopolyhedrovirus. Journal of Virology 88:23, pages 13781-13797.
Crossref
Yulia V. Lyupina, Olga V. Orlova, Svetlana B. Abaturova, Svetlana N. Beljelarskaya, Andrey N. Lavrov & Victor S. Mikhailov. (2014) Egress of budded virions of Autographa californica nucleopolyhedrovirus does not require activity of Spodoptera frugiperda HSP/HSC70 chaperones. Virus Research 192, pages 1-5.
Crossref
Barry Buckland, Robert Boulanger, Mireli Fino, Indresh Srivastava, Kathy Holtz, Nikolai Khramtsov, Clifton McPherson, Jamal Meghrous, Paul Kubera & Manon M.J. Cox. (2014) Technology transfer and scale-up of the Flublok? recombinant hemagglutinin (HA) influenza vaccine manufacturing process. Vaccine 32:42, pages 5496-5502.
Crossref
Bingqing Liu, Ruiqin Wang, Fang Wu, Xiaodong Xu & Hongying Chen. (2014) Rapid production of HIV-1 neutralizing antibodies in baculovirus infected insect cells. Protein Expression and Purification 99, pages 87-93.
Crossref
Alejandro Negrete, Amrita Pai & Joseph Shiloach. (2014) Use of hollow fiber tangential flow filtration for the recovery and concentration of HIV virus-like particles produced in insect cells. Journal of Virological Methods 195, pages 240-246.
Crossref
K.A. Schat. 2014. Encyclopedia of Agriculture and Food Systems. Encyclopedia of Agriculture and Food Systems 315 332 .
Steve Reid, Leslie Chan & Monique M. van Oers. 2014. Mass Production of Beneficial Organisms. Mass Production of Beneficial Organisms 437 482 .
Heike Cremer, Ingrid Bechtold, Marion Mahnke & René Assenberg. 2014. Animal Cell Biotechnology. Animal Cell Biotechnology 395 417 .
A. Contreras-Gómez, A. Sánchez-Mirón, F. García-Camacho, E. Molina-Grima & Y. Chisti. (2014) Protein production using the baculovirus-insect cell expression system. Biotechnology Progress 30:1, pages 1-18.
Crossref
Quan Nguyen, Lars Nielsen & Steven Reid. (2013) Genome Scale Transcriptomics of Baculovirus-Insect Interactions. Viruses 5:11, pages 2721-2747.
Crossref
M.S. Beato, M. Realpe-Quintero, F. Bonfante, M. Mancin, S. Ormelli, C. Terregino, C. Gonzalez-Hernandez & I. Capua. (2013) Cross-clade protection against H5N1 HPAI strains recently isolated from commercial poultry in Egypt with a single dose of a baculovirus based vaccine. Vaccine 31:44, pages 5075-5081.
Crossref
Quan Nguyen, Leslie C.L. Chan, Lars K. Nielsen & Steven Reid. (2013) Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus. Virology 444:1-2, pages 158-170.
Crossref
Fuxiao Liu, Xiaodong Wu, Lin Li, Zengshan Liu & Zhiliang Wang. (2013) Use of baculovirus expression system for generation of virus-like particles: Successes and challenges. Protein Expression and Purification 90:2, pages 104-116.
Crossref
Lily P. H. Yang. (2013) Recombinant Trivalent Influenza Vaccine (Flublok®): A Review of Its Use in the Prevention of Seasonal Influenza in Adults. Drugs 73:12, pages 1357-1366.
Crossref
Elisa Crisci, Juan Bárcena & María Montoya. (2013) Virus-like particle-based vaccines for animal viral infections. Inmunología 32:3, pages 102-116.
Crossref
Fuxiao Liu, Xiaodong Wu, Lin Li, Shengqiang Ge, Zengshan Liu & Zhiliang Wang. (2013) Virus-like particles: Promising platforms with characteristics of DIVA for veterinary vaccine design. Comparative Immunology, Microbiology and Infectious Diseases 36:4, pages 343-352.
Crossref
Hoai T. Huynh, Trinh T. B. Tran, Leslie C. L. Chan, Lars K. Nielsen & Steven Reid. (2013) Decline in baculovirus-expressed recombinant protein production with increasing cell density is strongly correlated to impairment of virus replication and mRNA expression. Applied Microbiology and Biotechnology 97:12, pages 5245-5257.
Crossref
Chao-Yi Teng, Shou-Lin Chang, Meng-Feng Tsai & Tzong-Yuan Wu. (2013) α-Synuclein and β-synuclein enhance secretion protein production in baculovirus expression vector system. Applied Microbiology and Biotechnology 97:9, pages 3875-3884.
Crossref
Sylvie Juliant, Marylêne Lévêque, Pierre Cérutti, Annick Ozil, Sylvie Choblet, Marie-Luce Violet, Marie-Christine Slomianny, Anne Harduin-Lepers & Martine Cérutti. 2013. Glycosylation Engineering of Biopharmaceuticals. Glycosylation Engineering of Biopharmaceuticals 59 77 .
Fuxiao Liu, Shengqiang Ge, Lin Li, Xiaodong Wu, Zengshan Liu & Zhiliang Wang. (2012) Virus-like particles: potential veterinary vaccine immunogens. Research in Veterinary Science 93:2, pages 553-559.
Crossref
Elisa Crisci, Juan Bárcena & María Montoya. (2012) Virus-like particles: The new frontier of vaccines for animal viral infections. Veterinary Immunology and Immunopathology 148:3-4, pages 211-225.
Crossref
Leila Matindoost, Leslie C.L. Chan, Ying Mei Qi, Lars K. Nielsen & Steven Reid. (2012) Suspension culture titration: A simple method for measuring baculovirus titers. Journal of Virological Methods 183:2, pages 201-209.
Crossref
Quan Nguyen, Robin W. Palfreyman, Leslie C. L. Chan, Steven Reid & Lars K. Nielsen. (2012) Transcriptome Sequencing of and Microarray Development for a Helicoverpa zea Cell Line to Investigate In Vitro Insect Cell-Baculovirus Interactions. PLoS ONE 7:5, pages e36324.
Crossref
Hoai T. Huynh, Leslie C. L. Chan, Trinh T. B. Tran, Lars K. Nielsen & Steven Reid. (2012) Improving the robustness of a low‐cost insect cell medium for baculovirus biopesticides production, via hydrolysate streamlining using a tube bioreactor‐based statistical optimization routine. Biotechnology Progress 28:3, pages 788-802.
Crossref
Laura A. Palomares, Jimmy A. Mena & Octavio T. Ram?rez. (2012) Simultaneous expression of recombinant proteins in the insect cell-baculovirus system: Production of virus-like particles. Methods 56:3, pages 389-395.
Crossref
Trinh T.B. Tran, Stefanie Dietmair, Leslie C.L. Chan, Hoai T. Huynh, Lars K. Nielsen & Steven Reid. (2012) Development of quenching and washing protocols for quantitative intracellular metabolite analysis of uninfected and baculovirus-infected insect cells. Methods 56:3, pages 396-407.
Crossref
Manon M.J. Cox. (2012) Recombinant protein vaccines produced in insect cells. Vaccine 30:10, pages 1759-1766.
Crossref
Amine A. Kamen, Marc G. Aucoin, Otto-Wilhelm Merten, Paula Alves, Yoshifumi Hashimoto, Kari Airenne, Yu-Chen Hu, Mauro Mezzina & Monique M. van Oers. (2011) An initiative to manufacture and characterize baculovirus reference material. Journal of Invertebrate Pathology 107, pages S113-S117.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.