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Review

Pyoderma gangrenosum: challenges and solutions

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Pages 285-293 | Published online: 28 May 2015

Keep up to date with the latest research on this topic with citation updates for this article.

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Beenish Fayyaz. (2018) Pyoderma gangrenosum in primary care setting: the challenges involved. Journal of Community Hospital Internal Medicine Perspectives 8:2, pages 57-59.
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Articles from other publishers (57)

Jacqueline K. Nguyen, Zachary Holmes & Robert I. Kelly. (2023) Intravenous immunoglobulin treatment for refractory pyoderma gangrenosum. Australasian Journal of Dermatology 64:2, pages 221-228.
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Akriti Goel, Garima, Navidha Aggarwal, Garima Kapoor, Hitesh Chopra, Mamta Naagar, Aishwarya Gangwar, Prachi Singh & Kuldeep Dhama. (2023) Skin and Soft Tissue Infections: Current Advancement in Epidemiology, Pathogenesis and Management. Journal of Pure and Applied Microbiology 17:1, pages 89-111.
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Veronika Šopíková & Jan Šternberský. (2022) Pyoderma gangraenosum induced by surgery. Dermatologie pro praxi 16:3, pages 135-138.
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Myroslav V. Rosul & Bohdan M. Patskan. (2022) PYODERMA GANGRENOSUM AS THE ONLY MANIFESTATION OF ASYMPTOMATIC NEWLY DIAGNOSED NONSPECIFIC ULCERATIVE COLITIS. CLINICAL CASE. Wiadomości Lekarskie 75:10, pages 2549-2553.
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Filipa David, Rafaela Lopes Freitas, Rute Brás-Cruz, Joana Rocha & Cristina Rosário. (2022) A Case of Recurrent Idiopathic Pyoderma Gangrenosum. Cureus.
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Kenshi Yamasaki, Keiichi Yamanaka, Yiwei Zhao, Shunsuke Iwano, Keiko Takei, Koji Suzuki & Toshiyuki Yamamoto. (2022) Adalimumab in Japanese patients with active ulcers of pyoderma gangrenosum: Final analysis of a 52‐week phase 3 open‐label study . The Journal of Dermatology 49:5, pages 479-487.
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Babak Abdolkarimi, Ali Amanati & Gholamreza Bahoush Mehdiabadi. (2022) Cutaneous diphtheria complicated oncologic reconstruction surgery in osteosarcoma. Clinical Case Reports 10:2.
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Faridha Ilyas. (2022) Successful low-dose corticosteroid treatment of aggressive pyoderma gangrenosum with irritable bowel syndrome: a case report. Acta Dermatovenerologica Alpina Pannonica et Adriatica 31:3.
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Richard F. Kraus, Michael A. Gruber & Martin Kieninger. (2021) The influence of extracellular tissue on neutrophil function and its possible linkage to inflammatory diseases. Immunity, Inflammation and Disease 9:4, pages 1237-1251.
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Tridip Dutta Baruah, Rubik Ray & Manju R. (2021) Pyoderma Gangrenosum: An Ulcer With Unorthodox Treatment. Cureus.
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Madeleine Barbe, Andrea Batra, Stephanie Golding, Olivia Hammond, Jacqueline C. Higgins, Amber O’Connor & Tracey C. Vlahovic. (2021) Pyoderma Gangrenosum. Clinics in Podiatric Medicine and Surgery 38:4, pages 577-588.
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Nawaf J. Shatnawi, Nabil A. Al-Zoubi, Lujain A. Al-Bakkar, Laith M. Gharaibeh & Shadi Hamouri. (2021) Nonhealing Leg Ulcer as the Presentation of Sarcoidosis: A Case Report. The International Journal of Lower Extremity Wounds, pages 153473462110378.
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Vijay Kodumudi, David Lam & Kanishka Rajput. (2021) Pain Control in Dermatologic Conditions. Current Pain and Headache Reports 25:6.
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Zephania Saitabau Abraham, Edwin Peter Thomas & Aveline Aloyce Kahinga. (2021) Unilateral Pyoderma gangrenosum of the external ear in a resource‐limited setting: Case report and literature review. Clinical Case Reports 9:4, pages 2016-2018.
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Isaac Rodriguez, Tricia Conti & Nina Bionda. (2021) Microenvironment Influence of a Novel Bioengineered Wound Product, APIS®: A Preliminary In Vitro Analysis of Inflammatory Marker and Growth Factor Secretion. International Journal of Biomaterials 2021, pages 1-10.
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Kazuo Takahashi, Takaharu Ikeda, Kae Yokoyama & Tamihiro Kawakami. (2020) Cutaneous ulcer resembling pyoderma gangrenosum in a patient with antiphospholipid syndrome. Journal of Cutaneous Immunology and Allergy 4:1, pages 17-18.
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Anokhi Saklecha, Wynnis Tom & Jessica Sprague. (2020) Resolution of chronic recurrent pyoderma gangrenosum with latent tuberculosis treatment. Pediatric Dermatology 38:1, pages 181-183.
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Carter Haag, Trevor Hansen, Tamar Hajar, Emile Latour, Jesse Keller, Kanade Shinkai & Alex G. Ortega-Loayza. (2021) Comparison of Three Diagnostic Frameworks for Pyoderma Gangrenosum. Journal of Investigative Dermatology 141:1, pages 59-63.
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Teresa Alonso‐León, Heidi H. Hernández‐Ramírez, Veronica Fonte‐Avalos, Sonia Toussaint‐Caire, María Vega‐Memije & Adriana Lozano‐Platonoff. (2020) The great imitator with no diagnostic test: pyoderma gangrenosum. International Wound Journal 17:6, pages 1774-1782.
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Kenshi Yamasaki, Keiichi Yamanaka, Yiwei Zhao, Shunsuke Iwano, Keiko Takei, Koji Suzuki & Toshiyuki Yamamoto. (2020) Adalimumab in Japanese patients with active ulcers of pyoderma gangrenosum: Twenty‐six‐week phase 3 open‐label study. The Journal of Dermatology 47:12, pages 1383-1390.
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J.D. Lu, M.M. Hobbs, W.W. Huang, A.G. Ortega‐Loayza & A. Alavi. (2020) Identification and evaluation of outcome measurement instruments in pyoderma gangrenosum: a systematic review*. British Journal of Dermatology 183:5, pages 821-828.
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F -C Liu, N -T Liu & T -Y Huang. (2020) Ulcerative colitis with refractory pyoderma gangrenosum. QJM: An International Journal of Medicine 113:8, pages 567-568.
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Amy Xu, Amrita Balgobind, Andrew Strunk, Amit Garg & Allireza Alloo. (2020) Prevalence estimates for pyoderma gangrenosum in the United States: An age- and sex-adjusted population analysis. Journal of the American Academy of Dermatology 83:2, pages 425-429.
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Margarete Anna Wieczorek. (2020) Diagnosis and treatment of peristomal pyoderma gangrenosum: a case report. Gastrointestinal Nursing 18:Sup4, pages S10-S11.
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Xiaowen Huang, Kai Han, Ruzeng Xue, Li Li, Kang Zeng & Liuping Liang. (2020) Successful treatment with oral methylprednisolone and cyclosporine for refractory pyoderma gangrenosum in children: Report of a case and review of the literature. Clinical Case Reports 8:3, pages 416-419.
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Monica Shah, Muskaan Sachdeva, Amnah Gefri & Abdulhadi Jfri. (2019) Paraneoplastic pyoderma gangrenosum in solid organ malignancy: a literature review. International Journal of Dermatology 59:2, pages 154-158.
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Florencia Giraudo, Eugenia Miraglia, Martín Yantorno, María Laura Garbi, María Roxana Maradeo, Fernando Baldoni, Francisco Tufare & Gustavo Javier Correa. (2020) Prevalence of pyoderma gangrenosum and Sweet�s syndrome in inflammatory bowel disease at a tertiary healthcare center.. Revista Española de Enfermedades Digestivas.
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Irena Peteln, Mateja Dolenc‐Voljč & Vesna Jurčić. (2019) Neutrophilic dermatosis of the dorsal hands (acral Sweet syndrome) with predominantly lymphocytic dermal infiltrate. Journal of Cutaneous Pathology 47:1, pages 104-107.
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Asma Asif Amir Ali, Angelo Valerio Marzano & Afsaneh Alavi. 2020. Local Wound Care for Dermatologists. Local Wound Care for Dermatologists 187 194 .
John Jairo Dávila Rodríguez, Liliana García, Karla Aguilar Benavides & Yadira Aguilar. (2019) Pioderma gangrenoso multifocal y exuberante. Piel 34:8, pages 506-508.
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Paula García Cámara, María Luisa Zubiri Ara & Santiago García López. (2019) Ustekinumab en un paciente con pioderma gangrenoso y enfermedad de Crohn refractaria. Medicina Clínica 153:8, pages e35-e36.
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Paula García Cámara, María Luisa Zubiri Ara & Santiago García López. (2019) Ustekinumab in a patient with pyoderma gangrenosum and refractory Crohn's disease. Medicina Clínica (English Edition) 153:8, pages e35-e36.
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Francisca Alves & Margarida Gonçalo. (2019) Suspected inflammatory rheumatic diseases in patients presenting with skin rashes. Best Practice & Research Clinical Rheumatology 33:4, pages 101440.
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Luis J. Borda, Lulu L. Wong, Angelo V. Marzano & Alex G. Ortega-Loayza. (2019) Extracutaneous involvement of pyoderma gangrenosum. Archives of Dermatological Research 311:6, pages 425-434.
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Matthew DaCunha, Spyros Siscos, Malia Downing, Isadore Tarantino & John Hall. (2019) Pyoderma gangrenosum controlled with rituximab. JAAD Case Reports 5:7, pages 593-595.
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Giorgia Guaitoli, Federico Piacentini, Claudia Omarini, Alessia Andreotti, Enza Palma, Simona Papi, Chiara De Pietri, Andrea Conti, Stefano Cascinu & Giovanni Tazzioli. (2018) Post-surgical pyoderma gangrenosum of the breast: needs for early diagnosis and right therapy. Breast Cancer 26:4, pages 520-523.
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Federico Diotallevi, Anna Campanati, Giulia Radi, Valerio Brisigotti, Elisa Molinelli, Donatella Brancorsini & Annamaria Offidani. (2019) Pyoderma gangrenosum successfully treated with golimumab: Case report and review of the literature. Dermatologic Therapy, pages e12928.
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Hakim Ben Abdallah, Karsten Fogh & Rikke Bech. (2019) Pyoderma gangrenosum and tumour necrosis factor alpha inhibitors: A semi‐systematic review. International Wound Journal 16:2, pages 511-521.
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Isabella Plumptre, Daniel Knabel & Kenneth Tomecki. (2018) Pyoderma Gangrenosum: A Review for the Gastroenterologist. Inflammatory Bowel Diseases 24:12, pages 2510-2517.
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Xiao-Li Li, Zhi-Gang Ma, Wen-Hui Huang, Er-Qing Chai & Yun-Fei Hao. (2018) Successful treatment of pyoderma gangrenosum with concomitant immunoglobulin A nephropathy: A case report and review of literature. World Journal of Clinical Cases 6:13, pages 703-706.
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Bilal Abdul-fattah, Maher Al-Muriesh & Chang-zheng Huang. (2018) Efficacy of topical calcineurin inhibitors in pyoderma gangrenosum. Dermatologic Therapy 31:5, pages e12697.
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Gokal Hilal, Gonenli G, Armutlu A & Akay OM. (2018) A case of generalized bullous pyoderma gangrenosum with myelodysplastic syndrome. Journal of Dermatology & Cosmetology 2:2.
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Santo Raffaele Mercuri, Giovanni Paolino, Eduardo De Flammineis, Dario Didona & Pina Brianti. (2017) Retracted: Successful treatment of pyoderma gangrenosum with anakinra in a patient with Wiskott–Aldrich syndrome. Dermatologic Therapy 31:2.
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Loraine Entringer Falqueto, Marcos Lyra Kaddoum, Marcio Maia Lamy de Miranda & Henrique Faria Ramos. (2018) Acquired stenosis of external auditory canal secondary to paraneoplastic manifestation of renal cancer. Brazilian Journal of Otorhinolaryngology 84:2, pages 249-251.
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Michael Doulberis, Jörg Dähn, Jannis Kountouras, Volker Maier, Arthur Helbling & Patrick Dubach. (2018) A RARE CASE OF CROHN DISEASE COMPLICATED WITH STEROID MONOTHERAPY-RELATED RETROPHARYNGEAL ABSCESS AND INITIALLY MISINTERPRETED PYODERMA GANGRENOSUM DEVELOPMENT. Gastroenterology Nursing 41:4, pages 347-351.
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Amanda Mun Yee Slocum. (2017) A surgeon’s nightmare: pyoderma gangrenosum with pathergy effect mimicking necrotising fasciitis. BMJ Case Reports, pages bcr-2017-222145.
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Yan-Yun Jiang, Ji Li, Yue Li, Qiang Wang, Shuang Liu, Kai Fang, Jia-Ming Qian & Hong-Zhong Jin. (2017) Comparison of Clinical Features between Pyoderma Gangrenosum Concomitant by Inflammatory Bowel Disease and Idiopathic Pyoderma Gangrenosum. Chinese Medical Journal 130:22, pages 2674-2679.
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Vincent Maida & Jason Corban. (2017) Topical Medical Cannabis: A New Treatment for Wound Pain—Three Cases of Pyoderma Gangrenosum. Journal of Pain and Symptom Management 54:5, pages 732-736.
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Sideris Nanoudis, Afroditi Tsona, Olga Tsachouridou, Petros Morfesis, Georgia Loli, Adamantini Georgiou, Pantelis Zebekakis & Symeon Metallidis. (2017) Pyoderma gangrenosum in a patient with chronic granulomatous disease. Medicine 96:31, pages e7718.
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M. Vaysse-vic, P.-A. Mathieu, A. Charissoux, J.-L. Charissoux & P.-S. Marcheix. (2017) Pyoderma gangrenosum ou fasciite nécrosante ? À propos d’un cas d’errance diagnostique et thérapeutique. Revue de Chirurgie Orthopédique et Traumatologique 103:4, pages 427-429.
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M. Vaysse-Vic, P.-A. Mathieu, A. Charissoux, J.-L. Charissoux & P.-S. Marcheix. (2017) Pyoderma gangrenosum or necrotising fasciitis? Diagnostic and therapeutic wanderings. Orthopaedics & Traumatology: Surgery & Research 103:4, pages 615-617.
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Afsaneh Alavi, Lars E. French, Mark D. Davis, Alain Brassard & Robert S. Kirsner. (2017) Pyoderma Gangrenosum: An Update on Pathophysiology, Diagnosis and Treatment. American Journal of Clinical Dermatology 18:3, pages 355-372.
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A. Coster, J.-L. Dargent, N. de Visscher, P. Levecque & P.-P. Roquet-Gravy. (2017) Pyoderma gangrenosum avec anticorps anti-cytoplasme des neutrophiles de type anti-protéinase 3 (PR3-ANCA) induits par le propylthiouracile. Annales de Dermatologie et de Vénéréologie 144:5, pages 368-373.
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Anastasia Atanasova Chokoeva, José Carlos Cardoso, Uwe Wollina & Georgi Tchernev. (2016) Pyoderma gangrenosum—a novel approach?Pyoderma gangraenosum – ein neuer Ansatz?. Wiener Medizinische Wochenschrift 167:3-4, pages 58-65.
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Verena Mony Paes de Freitas, Silvia Marcondes Pereira, Mílvia Maria Simões e Silva Enokihara & Silmara da Costa Pereira Cestari. (2017) Pyoderma gangrenosum associated with left iliac vein compression syndrome: presentation of difficult diagnosis. Anais Brasileiros de Dermatologia 92:5 suppl 1, pages 129-131.
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Esra AdışenFunda ErduranMehmet Ali Gürer. (2016) Pyoderma Gangrenosum. The International Journal of Lower Extremity Wounds 15:2, pages 148-154.
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A. Costanzo. (2015) Towards a targeted therapy for pyoderma gangrenosum. British Journal of Dermatology 173:5, pages 1124-1124.
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