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Original Research

Frequency of germline mutations in BRCA1 and BRCA2 in ovarian cancer patients and their effect on treatment outcome

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Pages 6275-6284 | Published online: 08 Jul 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Srinivas Teppala, Brent Hodgkinson, Sandi Hayes, Paul Scuffham & Haitham Tuffaha. (2023) A review of the cost-effectiveness of genetic testing for germline variants in familial cancer. Journal of Medical Economics 26:1, pages 19-33.
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Dinh-Toi Chu, Mai Vu Ngoc Suong, Hue Vu Thi, Thuy-Duong Vu, Manh-Hung Nguyen & Vijai Singh. (2023) The expression and mutation of BRCA1/2 genes in ovarian cancer: a global systematic study. Expert Review of Molecular Diagnostics 23:1, pages 53-61.
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Articles from other publishers (12)

Giovanni Innella, Lea Godino, Giulia Erini, Antonio De Leo, Donatella Santini, Anna Myriam Perrone, Pierandrea De Iaco, Claudio Zamagni & Daniela Turchetti. (2023) Factors predicting BRCA1/2 pathogenic variants in patients with ovarian cancer: a systematic review with meta-analysis . Journal of Clinical Pathology 76:8, pages 510-517.
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Jacek Glajzer, Dan Cacsire Castillo-Tong, Rolf Richter, Ignace Vergote, Hagen Kulbe, Adriaan Vanderstichele, Ilary Ruscito, Fabian Trillsch, Alexander Mustea, Caroline Kreuzinger, Charlie Gourley, Hani Gabra, Eliane T. Taube, Oliver Dorigo, David Horst, Carlotta Keunecke, Joanna Baum, Timothy Angelotti, Jalid Sehouli & Elena Ioana Braicu. (2022) Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium. Annals of Surgical Oncology 30:1, pages 35-45.
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Mohamed M. Rizk, Nour M. El-etreby, Lama M. El-Attar, Eman A. Elzyat & Marwa H. Saied. (2022) A case–control study of BRCA1 founder mutations 185delAG and 5382insC in a cohort of Egyptian ovarian cancer patients using pyrosequencing technique. Egyptian Journal of Medical Human Genetics 23:1.
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Yazhuo Wang, Na Li, Yanan Ren & Jing Zhao. (2022) Association of BRCA1 /2 mutations with prognosis and surgical cytoreduction outcomes in ovarian cancer patients: An updated meta‐analysis . Journal of Obstetrics and Gynaecology Research 48:9, pages 2270-2284.
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Jeffrey C.H. Goh, Charlie Gourley, David S P Tan, Angélica Nogueira-Rodrigues, Hesham Elghazaly, Marc Edy Pierre, Gonzalo Giornelli, Byoung-Gie Kim, Flavia Morales–Vasquez & Alexandra Tyulyandina. (2022) Optimizing treatment selection and sequencing decisions for first-line maintenance therapy of newly diagnosed advanced ovarian cancer – International considerations amongst upper middle- and high-income countries (UMIC and HIC). Gynecologic Oncology Reports 42, pages 101028.
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Megan A. Czekalski, Rachelle C. Huziak, Andrea L. Durst, Sarah Taylor & Phuong L. Mai. (2022) Mainstreaming Genetic Testing for Epithelial Ovarian Cancer by Oncology Providers: A Survey of Current Practice. JCO Precision Oncology:6.
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Nerina C. Van der Merwe, Herkulaas MvE Combrink, Kholiwe S. Ntaita & Jaco Oosthuizen. (2022) Prevalence of Clinically Relevant Germline BRCA Variants in a Large Unselected South African Breast and Ovarian Cancer Cohort: A Public Sector Experience. Frontiers in Genetics 13.
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Sabrina Piedimonte, Marcus Q. Bernardini, Taymaa May, Paulina Cybulska, Sarah E. Ferguson, Stephane Laframboise, Geneviève Bouchard‐Fortier, Lisa Avery & Liat Hogen. (2021) Treatment outcomes and predictive factors in patients ≥70 years old with advanced ovarian cancer. Journal of Surgical Oncology 125:4, pages 736-746.
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Fathi Azribi, Ehab Abdou, Emad Dawoud, Mohamed Ashour, Amgad Kamal, Mohamed Al Sayed & Ikram Burney. (2021) Prevalence of BRCA1 and BRCA2 pathogenic sequence variants in ovarian cancer patients in the Gulf region: the PREDICT study. BMC Cancer 21:1.
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Cécile Le Page, Setor Amuzu, Kurosh Rahimi, Walter Gotlieb, Jiannis Ragoussis & Patricia N. Tonin. (2021) Lessons learned from understanding chemotherapy resistance in epithelial tubo-ovarian carcinoma from BRCA1and BRCA2mutation carriers. Seminars in Cancer Biology 77, pages 110-126.
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Yingli Zhang, Xiaoliang Shi, Jiejie Zhang, Xi Chen, Peng Zhang, Angen Liu & Tao Zhu. (2021) A comprehensive analysis of somatic alterations in Chinese ovarian cancer patients. Scientific Reports 11:1.
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Stephanie Alimena, Lauren Scarpetti, Erica L Blouch, Linda Rodgers, Kristen Shannon, Marcela Del Carmen, Annekathryn Goodman, Whitfield B Growdon, Eric Eisenhauer & Rachel Clark Sisodia. (2020) Factors associated with referral and completion of genetic counseling in women with epithelial ovarian cancer. International Journal of Gynecologic Cancer 30:9, pages 1397-1403.
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