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International Journal of Chronic Obstructive Pulmonary Disease Volume 11, 2016 - Issue
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Original Research

Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants

Anna Pomerenke1 Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation TrustCorrespondence[email protected]
,
Simon R Lea1 Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust
,
Sarah Herrick2 Institute of Inflammation and Repair, Manchester Academic Health Science Centre, University of Manchester, Manchester
,
Mark A Lindsay3 Department of Pharmacy and Pharmacology, University of Bath, Bath, UK
&
Dave Singh1 Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust
Pages 2409-2417 | Published online: 29 Sep 2016

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Pavithra Dhamodharan & Mohanapriya Arumugam. (2020) Multiple Gene Expression Dataset Analysis Reveals Toll-Like Receptor Signaling Pathway is Strongly Associated With Chronic Obstructive Pulmonary Disease Pathogenesis. COPD: Journal of Chronic Obstructive Pulmonary Disease 17:6, pages 684-698.
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Karolina Sidletskaya, Tatyana Vitkina & Yulia Denisenko. (2020) The Role of Toll-Like Receptors 2 and 4 in the Pathogenesis of Chronic Obstructive Pulmonary Disease. International Journal of Chronic Obstructive Pulmonary Disease 15, pages 1481-1493.
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Hong Guo-Parke, Dermot Linden, Sinéad Weldon, Joseph C. Kidney & Clifford C. Taggart. (2022) Deciphering Respiratory-Virus-Associated Interferon Signaling in COPD Airway Epithelium. Medicina 58:1, pages 121.
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Lynne Prince, Lisa Parker & Ian Sabroe. 2022. Encyclopedia of Respiratory Medicine. Encyclopedia of Respiratory Medicine 264 270 .
Karolina A. Sidletskaya, Tatyana I. Vitkina, Yulia K. Denisenko & Elena E. Mineeva. (2021) Role of Toll-Like Receptor 2 in Regulation of T-Helper Immune Response in Chronic Obstructive Pulmonary Disease. Canadian Respiratory Journal 2021, pages 1-8.
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Yaser Hosny Ali Elewa, Osamu Ichii, Teppei Nakamura & Yasuhiro Kon. (2021) Dual Effect of Bleomycin on Histopathological Features of Lungs and Mediastinal Fat-Associated Lymphoid Clusters in an Autoimmune Disease Mouse Model. Frontiers in Immunology 12.
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Mirco Govoni, Michele Bassi, Stefano Vezzoli, Germano Lucci, Aida Emirova, Marie Anna Nandeuil, Stefano Petruzzelli, Gera L. Jellema, Ebenezer K. Afolabi, Brendan Colgan, Brian Leaker, Oliver Kornmann, Kai Michael Beeh, Henrik Watz & Dave Singh. (2020) Sputum and blood transcriptomics characterisation of the inhaled PDE4 inhibitor CHF6001 on top of triple therapy in patients with chronic bronchitis. Respiratory Research 21:1.
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Sara Ghaffarpour, Abbas Foroutan, Nayere Askari, Fatemeh Mashhadi Abbas, Eisa Salehi, Maryam Nikoonejad, Mohammad Mehdi Naghizadeh, Maryam Eskandarian, Keivan Gohari Moghadam, Hassan Mohammad Hosseini Akbari, Mohammad Ebrahim Yarmohammadi & Tooba Ghazanfari. (2020) SP-A and TLR4 localization in lung tissue of SM-exposed patients. International Immunopharmacology 80, pages 105936.
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Suidong Ouyang, Caini Liu, Jianxin Xiao, Xing Chen, Andy C. Lui & Xiaoxia Li. (2020) Targeting IL-17A/glucocorticoid synergy to CSF3 expression in neutrophilic airway diseases. JCI Insight 5:3.
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Shuang Bai, Rui Ye, Cuihong Wang, Pengbo Sun & Li Zhao. (2020) Comparative analysis of pathophysiological parameters between emphysematous smokers and emphysematous patients with COPD. Scientific Reports 10:1.
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Simon Lea, Alexandra Metryka, Jian Li, Andrew Higham, Charles Bridgewood, Gino Villetti, Maurizio Civelli, Fabrizio Facchinetti & Dave Singh. (2019) The modulatory effects of the PDE4 inhibitors CHF6001 and roflumilast in alveolar macrophages and lung tissue from COPD patients. Cytokine 123, pages 154739.
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Javaid, Yasmeen & Choi. (2019) Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods. Pharmaceutics 11:9, pages 441.
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Brianna Atto, Mathew Suji Eapen, Pawan Sharma, Urs Frey, Alaina J. Ammit, James Markos, Collin Chia, Josie Larby, Greg Haug, Heinrich C. Weber, George Mabeza, Stephen Tristram, Stephen Myers, Dominic P. Geraghty, Katie L. Flanagan, Philip M. Hansbro & Sukhwinder Singh Sohal. (2019) New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways. Clinical Science 133:14, pages 1663-1703.
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Muhammad Ayaz Anwar, Masaud Shah, Jason Kim & Sangdun Choi. (2018) Recent clinical trends in Toll‐like receptor targeting therapeutics. Medicinal Research Reviews 39:3, pages 1053-1090.
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Simon Lea, Alexandra Metryka, Jian Li, Andrew Higham, Charles Bridgewood, Gino Villetti, Maurizio Civelli, Fabrizio Facchinetti & Dave Singh. (2019) WITHDRAWN: The modulatory effects of the PDE4 inhibitors CHF6001 and roflumilast in alveolar macrophages and lung tissue from COPD patients. Cytokine: X, pages 100006.
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Soumya Chatterjee, Kaustav Chakraborty, Shauryabrota Dalui & Arindam Bhattacharyya. 2019. Oxidative Stress in Lung Diseases. Oxidative Stress in Lung Diseases 187 194 .
Anna Pomerenke. 2021. Three Dimensional Human Organotypic Models for Biomedical Research. Three Dimensional Human Organotypic Models for Biomedical Research 161 181 .

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