International Journal of Chronic Obstructive Pulmonary Disease, Volume 11, Issue (2016)

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International Journal of Chronic Obstructive Pulmonary Disease, Volume 11, Issue (2016)

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Original Research

Article
Efficacy and safety of fluticasone furoate/vilanterol or tiotropium in subjects with COPD at cardiovascular risk
Henry Covelli, Bonavuth Pek, Isabelle Schenkenberger, Catherine Scott-Wilson, Amanda Emmett & Courtney Crim
Pages: 1-12
Published online: 18 Dec 2015
AbstractforEfficacy and safety of fluticasone furoate/vilanterol or tiotropium in subjects with COPD at cardiovascular risk | Full Text | References | PDF (532.7 KB)
  • 98 Views
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Open Access
Article
The relationship between the number of natural teeth and airflow obstruction: a cross-sectional study using data from the Korean National Health and Nutrition Examination Survey
Sei Won Kim, Kyungdo Han, Shin Young Kim, Chan Kwon Park, Chin Kook Rhee & Hyoung Kyu Yoon
Pages: 13-21
Published online: 21 Dec 2015
AbstractforThe relationship between the number of natural teeth and airflow obstruction: a cross-sectional study using data from the Korean National Health and Nutrition Examination Survey | Full Text | References | PDF (440 KB)
  • 70 Views
  • 8 CrossRef citations
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Open Access
Article
Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients
Hye Yun Park, Hyun Lee, Won-Jung Koh, Seonwoo Kim, Ina Jeong, Hyeon-Kyoung Koo, Tae-Hyung Kim, Jin Woo Kim, Woo Jin Kim, Yeon-Mok Oh, Don D Sin, Seong Yong Lim, Sang-Do Lee & On behalf of the KOLD Study Group
Pages: 23-30
Published online: 22 Dec 2015
AbstractforAssociation of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients | Full Text | References | PDF (669.2 KB)
  • 79 Views
  • 11 CrossRef citations
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Open Access
Article
Cigarette smoke-induced lung inflammation in COPD mediated via LTB4/BLT1/SOCS1 pathway
Ran Dong, Liang Xie, Kaishun Zhao, Qiurui Zhang, Min Zhou & Ping He
Pages: 31-41
Published online: 22 Dec 2015
AbstractforCigarette smoke-induced lung inflammation in COPD mediated via LTB4/BLT1/SOCS1 pathway | Full Text | References | PDF (1.7 MB)
  • 87 Views
  • 9 CrossRef citations
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Open Access
Article
Impact of chronic obstructive pulmonary disease on postoperative recurrence in patients with resected non-small-cell lung cancer
Guangliang Qiang, Chaoyang Liang, Fei Xiao, Qiduo Yu, Huanshun Wen, Zhiyi Song, Yanchu Tian, Bin Shi, Yongqing Guo & Deruo Liu
Pages: 43-49
Published online: 29 Dec 2015
AbstractforImpact of chronic obstructive pulmonary disease on postoperative recurrence in patients with resected non-small-cell lung cancer | Full Text | References | PDF (829.2 KB)
  • 79 Views
  • 6 CrossRef citations
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Open Access
Article
Age-related annual decline of lung function in patients with COPD
Soo Jung Kim, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Ho Il Yoon, Sang-Min Lee, Jae-Joon Yim, Young Whan Kim, Sung Koo Han & Chul-Gyu Yoo
Pages: 51-60
Published online: 30 Dec 2015
AbstractforAge-related annual decline of lung function in patients with COPD | Full Text | References | PDF (284 KB)
  • 189 Views
  • 10 CrossRef citations
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Open Access
Article
Impact of individualized care on readmissions after a hospitalization for acute exacerbation of COPD
Simon L Adamson, Jane Burns, Pat G Camp, Don D Sin & Stephan F van Eeden
Pages: 61-71
Published online: 05 Jan 2016
AbstractforImpact of individualized care on readmissions after a hospitalization for acute exacerbation of COPD | Full Text | References | PDF (838 KB)
  • 71 Views
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Open Access

Review

Review Article
Specific role of combination aclidinium: formoterol in the treatment of chronic obstructive pulmonary disease
Maria Gabriella Matera, Alessandro Sanduzzi & Mario Cazzola
Pages: 73-79
Published online: 05 Jan 2016
AbstractforSpecific role of combination aclidinium: formoterol in the treatment of chronic obstructive pulmonary disease | Full Text | References | PDF (200.8 KB)
  • 51 Views
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Open Access
Review Article
Roflumilast: a review of its use in the treatment of COPD
Jadwiga A Wedzicha, Peter MA Calverley & Klaus F Rabe
Pages: 81-90
Published online: 06 Jan 2016
AbstractforRoflumilast: a review of its use in the treatment of COPD | Full Text | References | PDF (868.3 KB)
  • 627 Views
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Open Access

Letter

Letter
The effect of postgastrectomy reflux on lung functions
Kadri Atay
Pages: 91-92
Published online: 11 Jan 2016
CitationforThe effect of postgastrectomy reflux on lung functions | Full Text | References | PDF (153.1 KB)
  • 40 Views
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Open Access

Original Research

Article
Characteristics of reversible and nonreversible COPD and asthma and COPD overlap syndrome patients: an analysis of salbutamol Easyhaler data
Veronika Müller, Gabriella Gálffy, Márta Orosz, Zsuzsanna Kováts, Balázs Odler, Olof Selroos & Lilla Tamási
Pages: 93-101
Published online: 12 Jan 2016
AbstractforCharacteristics of reversible and nonreversible COPD and asthma and COPD overlap syndrome patients: an analysis of salbutamol Easyhaler data | Full Text | References | PDF (1.1 MB)
  • 88 Views
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Open Access
Article
Factors contributing to quality of life in COPD patients in South Korea
Hye-Young Kwon & Eugene Kim
Pages: 103-109
Published online: 13 Jan 2016
AbstractforFactors contributing to quality of life in COPD patients in South Korea | Full Text | References | PDF (623.9 KB)
  • 305 Views
  • 25 CrossRef citations
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Open Access
Article
COPD exacerbations associated with the modified Medical Research Council scale and COPD assessment test among Humana Medicare members
Margaret K Pasquale, Yihua Xu, Christine L Baker, Kelly H Zou, John G Teeter, Andrew M Renda, Cralen C Davis, Theodore C Lee & Joel Bobula
Pages: 111-121
Published online: 14 Jan 2016
AbstractforCOPD exacerbations associated with the modified Medical Research Council scale and COPD assessment test among Humana Medicare members | Full Text | References | PDF (665.4 KB)
  • 67 Views
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Open Access
Article
Cost-effectiveness of combination therapy umeclidinium/vilanterol versus tiotropium in symptomatic COPD Spanish patients
Marc Miravitlles, Juan B Gáldiz, Alicia Huerta, Alba Villacampa, David Carcedo & Francisco Garcia-Rio
Pages: 123-132
Published online: 18 Jan 2016
AbstractforCost-effectiveness of combination therapy umeclidinium/vilanterol versus tiotropium in symptomatic COPD Spanish patients | Full Text | References | PDF (1.1 MB)
  • 63 Views
  • 18 CrossRef citations
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Open Access
Article
Differences in outcomes between GOLD groups in patients with COPD in the TIOSPIR® trial
Daniel Dusser, Robert A Wise, Ronald Dahl, Antonio Anzueto, Kerstine Carter, Andy Fowler & Peter M Calverley
Pages: 133-145
Published online: 20 Jan 2016
AbstractforDifferences in outcomes between GOLD groups in patients with COPD in the TIOSPIR® trial | Full Text | References | PDF (606.5 KB)
  • 62 Views
  • 4 CrossRef citations
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Open Access

Letter

Letter
A possible pathological link among swallowing dysfunction, gastro-esophageal reflex, and sleep apnea in acute exacerbation in COPD patients
Shinji Teramoto
Pages: 147-150
Published online: 27 Jan 2016
First Page PreviewforA possible pathological link among swallowing dysfunction, gastro-esophageal reflex, and sleep apnea in acute exacerbation in COPD patients | Full Text | References | PDF (169.7 KB)
  • 65 Views
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Open Access

Original Research

Article
Sex differences in reported and objectively measured sleep in COPD
Jenny Theorell-Haglöw, Inga Sif Ólafsdóttir, Bryndís Benediktsdóttir, Thórarinn Gíslason, Eva Lindberg & Christer Janson
Pages: 151-160
Published online: 25 Jan 2016
AbstractforSex differences in reported and objectively measured sleep in COPD | Full Text | References | PDF (932.2 KB)
  • 63 Views
  • 11 CrossRef citations
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Open Access
Article
Association of incidental emphysema with annual lung function decline and future development of airflow limitation
Hyeon-Kyoung Koo, Kwang Nam Jin, Deog Kyeom Kim, Hee Soon Chung & Chang-Hoon Lee
Pages: 161-166
Published online: 27 Oct 2022
AbstractforAssociation of incidental emphysema with annual lung function decline and future development of airflow limitation | Full Text | References | PDF (363.5 KB)
  • 57 Views
  • 11 CrossRef citations
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Open Access
Article
Effect of salmeterol/fluticasone combination on the dynamic changes of lung mechanics in mechanically ventilated COPD patients: a prospective pilot study
Wei-Chih Chen, Hung-Hsing Chen, Chi-Huei Chiang, Yu-Chin Lee & Kuang-Yao Yang
Pages: 167-174
Published online: 27 Jan 2016
AbstractforEffect of salmeterol/fluticasone combination on the dynamic changes of lung mechanics in mechanically ventilated COPD patients: a prospective pilot study | Full Text | References | PDF (451.2 KB)
  • 52 Views
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Open Access
Article
The changing nature of chronic care and coproduction of care between primary care professionals and patients with COPD and their informal caregivers
Jane Murray Cramm & Anna Petra Nieboer
Pages: 175-182
Published online: 27 Jan 2016
AbstractforThe changing nature of chronic care and coproduction of care between primary care professionals and patients with COPD and their informal caregivers | Full Text | References | PDF (239.2 KB)
  • 85 Views
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Open Access
Article
Differences in the effects of Asian dust on pulmonary function between adult patients with asthma and those with asthma–chronic obstructive pulmonary disease overlap syndrome
Masanari Watanabe, Hisashi Noma, Jun Kurai, Hiroyuki Sano, Yasuto Ueda, Masaaki Mikami, Hiroyuki Yamamoto, Hirokazu Tokuyasu, Kazuhiro Kato, Tatsuya Konishi, Toshiyuki Tatsukawa, Eiji Shimizu & Hiroya Kitano
Pages: 183-190
Published online: 28 Jan 2016
AbstractforDifferences in the effects of Asian dust on pulmonary function between adult patients with asthma and those with asthma–chronic obstructive pulmonary disease overlap syndrome | Full Text | References | PDF (457.7 KB)
  • 44 Views
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Open Access

Corrigendum

Correction
Development of an integral assessment approach of health status in patients with obstructive airway diseases: the CORONA study [Corrigendum]
Page: 191
Published online: 27 Oct 2022
AbstractforDevelopment of an integral assessment approach of health status in patients with obstructive airway diseases: the CORONA study [Corrigendum] | Full Text | PDF (148.7 KB)
  • 43 Views
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Open Access

Original Research

Article
The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® (ENERGITO® study)
Kai-Michael Beeh, Eric Derom, José Echave-Sustaeta, Lars Grönke, Alan Hamilton, Dongmei Zhai & Leif Bjermer
Pages: 193-205
Published online: 27 Oct 2022
AbstractforThe lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® (ENERGITO® study) | Full Text | References | PDF (611.6 KB)
  • 84 Views
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Open Access
Article
“Frequent exacerbator” is a phenotype of poor prognosis in Japanese patients with chronic obstructive pulmonary disease
Ryusuke Tomioka, Tomotaka Kawayama, Masashi Suetomo, Takashi Kinoshita, Yoshihisa Tokunaga, Haruki Imaoka, Kazuko Matsunaga, Masaki Okamoto & Tomoaki Hoshino
Pages: 207-216
Published online: 27 Oct 2022
Abstractfor“Frequent exacerbator” is a phenotype of poor prognosis in Japanese patients with chronic obstructive pulmonary disease | Full Text | References | PDF (544.8 KB)
  • 51 Views
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Open Access
Article
No association between exacerbation frequency and stroke in patients with COPD
Claire Windsor, Emily Herrett, Liam Smeeth & Jennifer Kathleen Quint
Pages: 217-225
Published online: 02 Feb 2016
AbstractforNo association between exacerbation frequency and stroke in patients with COPD | Full Text | References | PDF (353.6 KB)
  • 54 Views
  • 5 CrossRef citations
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Open Access
Article
Antioxidant activity of pomegranate juice reduces emphysematous changes and injury secondary to cigarette smoke in an animal model and human alveolar cells
Ahmad Husari, Yasmine Hashem, Hala Bitar, Ghassan Dbaibo, Ghazi Zaatari & Marwan El Sabban
Pages: 227-237
Published online: 03 Feb 2016
AbstractforAntioxidant activity of pomegranate juice reduces emphysematous changes and injury secondary to cigarette smoke in an animal model and human alveolar cells | Full Text | References | PDF (6.6 MB)
  • 77 Views
  • 15 CrossRef citations
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Open Access
Article
Depression, body mass index, and chronic obstructive pulmonary disease – a holistic approach
Giuseppe Catalfo, Luciana Crea, Tiziana Lo Castro, Francesca Magnano San Lio, Giuseppe Minutolo, Gherardo Siscaro, Noemi Vaccino, Nunzio Crimi & Eugenio Aguglia
Pages: 239-249
Published online: 04 Feb 2016
AbstractforDepression, body mass index, and chronic obstructive pulmonary disease – a holistic approach | Full Text | References | PDF (612 KB)
  • 99 Views
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Open Access
Article
Determinants of change in physical activity during moderate-to-severe COPD exacerbation
Cristóbal Esteban, José M Quintana, Susana Garcia-Gutierrez, Ane Anton-Ladislao, Nerea Gonzalez, Marisa Baré, Nerea Fernández de Larrea, Francisco Rivas-Ruiz & For the IRYSS-COPD group
Pages: 251-261
Published online: 03 Feb 2016
AbstractforDeterminants of change in physical activity during moderate-to-severe COPD exacerbation | Full Text | References | PDF (433.2 KB)
  • 60 Views
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Open Access
Article
Functional respiratory imaging to assess the interaction between systemic roflumilast and inhaled ICS/LABA/LAMA
Wim Vos, Bita Hajian, Jan De Backer, Cedric Van Holsbeke, Samir Vinchurkar, Rita Claes, Annemie Hufkens, Paul M Parizel, Lieven Bedert & Wilfried De Backer
Pages: 263-271
Published online: 27 Oct 2022
AbstractforFunctional respiratory imaging to assess the interaction between systemic roflumilast and inhaled ICS/LABA/LAMA | Full Text | References | PDF (1 MB)
  • 74 Views
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Open Access
Article
Comorbidities associated with COPD in the Middle East and North Africa region: association with severity and exacerbations
Bassam Mahboub, Ashraf Alzaabi, Mohammed Nizam Iqbal, Hocine Salhi, Aïcha Lahlou, Luqman Tariq & Abdelkader El Hasnaoui
Pages: 273-280
Published online: 05 Feb 2016
AbstractforComorbidities associated with COPD in the Middle East and North Africa region: association with severity and exacerbations | Full Text | References | PDF (385.6 KB)
  • 71 Views
  • 3 CrossRef citations
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Open Access
Article
Impact of GOLD groups of chronic pulmonary obstructive disease on surgical complications
Hyung-Jun Kim, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han & Sun Mi Choi
Pages: 281-287
Published online: 10 Feb 2016
AbstractforImpact of GOLD groups of chronic pulmonary obstructive disease on surgical complications | Full Text | References | PDF (241.3 KB)
  • 97 Views
  • 9 CrossRef citations
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Open Access
Article
Relevance of dosage in adherence to treatment with long-acting anticholinergics in patients with COPD
José Luis Izquierdo, José Manuel Paredero & Raul Piedra
Pages: 289-293
Published online: 27 Oct 2022
AbstractforRelevance of dosage in adherence to treatment with long-acting anticholinergics in patients with COPD | Full Text | References | PDF (326.4 KB)
  • 55 Views
  • 14 CrossRef citations
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Open Access
Article
Responsiveness of blood and sputum inflammatory cells in Japanese COPD patients, non-COPD smoking controls, and non-COPD nonsmoking controls
Tomotaka Kawayama, Takashi Kinoshita, Kazuko Matsunaga, Akihiro Kobayashi, Tomoyuki Hayamizu, Malcolm Johnson & Tomoaki Hoshino
Pages: 295-303
Published online: 27 Oct 2022
AbstractforResponsiveness of blood and sputum inflammatory cells in Japanese COPD patients, non-COPD smoking controls, and non-COPD nonsmoking controls | Full Text | References | PDF (467.1 KB)
  • 61 Views
  • 3 CrossRef citations
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Open Access
Article
Self-management of health care behaviors for COPD: a systematic review and meta-analysis
Kate Jolly, Saimma Majothi, Alice J Sitch, Nicola R Heneghan, Richard D Riley, David J Moore, Elizabeth J Bates, Alice M Turner, Susan E Bayliss, Malcolm J Price, Sally J Singh, Peymane Adab, David A Fitzmaurice & Rachel E Jordan
Pages: 305-326
Published online: 17 Feb 2016
AbstractforSelf-management of health care behaviors for COPD: a systematic review and meta-analysis | Full Text | References | PDF (2 MB)
  • 610 Views
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Open Access

Study Protocol

Article
Study protocol for a randomized controlled trial of telephone-delivered cognitive behavior therapy compared with befriending for treating depression and anxiety in older adults with COPD
Colleen Doyle, David Dunt, David Ames, Marcia Fearn, Emily (Chuanmei) You & Sunil Bhar
Pages: 327-334
Published online: 12 Feb 2016
AbstractforStudy protocol for a randomized controlled trial of telephone-delivered cognitive behavior therapy compared with befriending for treating depression and anxiety in older adults with COPD | Full Text | References | PDF (332.2 KB)
  • 118 Views
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Open Access

Original Research

Article
Feasibility of spirometry in primary care to screen for COPD: a pilot study
Violaine Giraud, Alain Beauchet, Thierry Gomis & Thierry Chinet
Pages: 335-340
Published online: 12 Feb 2016
AbstractforFeasibility of spirometry in primary care to screen for COPD: a pilot study | Full Text | References | PDF (189.1 KB)
  • 103 Views
  • 6 CrossRef citations
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Open Access
Article
COPD characteristics and socioeconomic burden in Hellenic correctional institutions
Eleni G Bania, Zoe Daniil, Chrysa Hatzoglou, Evangelos C Alexopoulos, Eirini Mitsiki & Konstantinos I Gourgoulianis
Pages: 341-349
Published online: 12 Feb 2016
AbstractforCOPD characteristics and socioeconomic burden in Hellenic correctional institutions | Full Text | References | PDF (397.7 KB)
  • 67 Views
  • 3 CrossRef citations
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Open Access
Article
Mortality and economic burden of Krasnoyarsk region, Russia, caused by regular tobacco usage
Ivan P Artyukhov, Irina L Arshukova, Elena A Dobretsova & Andrey V Shulmin
Pages: 351-355
Published online: 22 Feb 2016
AbstractforMortality and economic burden of Krasnoyarsk region, Russia, caused by regular tobacco usage | Full Text | References | PDF (278.5 KB)
  • 55 Views
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Open Access
Article
Explaining the link between access-to-care factors and health care resource utilization among individuals with COPD
Minchul Kim, Jinma Ren, William Tillis, Carl V Asche, Inkyu K Kim & Carmen S Kirkness
Pages: 357-367
Published online: 22 Feb 2016
AbstractforExplaining the link between access-to-care factors and health care resource utilization among individuals with COPD | Full Text | References | PDF (415.9 KB)
  • 96 Views
  • 13 CrossRef citations
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Open Access
Article
Development of a spirometry T-score in the general population
Sei Won Lee, Hyun Kuk Kim, Seunghee Baek, Ji-Ye Jung, Young Sam Kim, Jae Seung Lee, Sang-Do Lee, David M Mannino & Yeon-Mok Oh
Pages: 369-379
Published online: 23 Feb 2016
AbstractforDevelopment of a spirometry T-score in the general population | Full Text | References | PDF (733.6 KB)
  • 48 Views
  • 1 CrossRef citations
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Open Access
Article
Early response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations
Peter M Calverley, Dirkje S Postma, Antonio R Anzueto, Barry J Make, Göran Eriksson, Stefan Peterson & Christine R Jenkins
Pages: 381-390
Published online: 25 Feb 2016
AbstractforEarly response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations | Full Text | References | PDF (866.1 KB)
  • 54 Views
  • 4 CrossRef citations
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Open Access
Article
Determinants of successful completion of pulmonary rehabilitation in COPD
Angel T Brown, Jason Hitchcock, Christopher Schumann, J Michael Wells, Mark T Dransfield & Surya P Bhatt
Pages: 391-397
Published online: 25 Feb 2016
AbstractforDeterminants of successful completion of pulmonary rehabilitation in COPD | Full Text | References | PDF (227.2 KB)
  • 225 Views
  • 9 CrossRef citations
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Open Access
Article
Chronic obstructive pulmonary disease and cognitive impairment in the Chinese elderly population: a large national survey
Peng Yin, Qingfeng Ma, Limin Wang, Peng Lin, Mei Zhang, Shige Qi & Zhihui Wang
Pages: 399-406
Published online: 25 Feb 2016
AbstractforChronic obstructive pulmonary disease and cognitive impairment in the Chinese elderly population: a large national survey | Full Text | References | PDF (679.5 KB)
  • 79 Views
  • 12 CrossRef citations
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Open Access
Article
A cross-sectional study to assess inhalation device handling and patient satisfaction in COPD
Marc Miravitlles, Jéssica Montero-Caballero, Frank Richard, Salud Santos, Juan Luis Garcia-Rivero, Francisco Ortega & Xavier Ribera
Pages: 407-415
Published online: 26 Feb 2016
AbstractforA cross-sectional study to assess inhalation device handling and patient satisfaction in COPD | Full Text | References | PDF (433.4 KB)
  • 138 Views
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Open Access

Corrigendum

Correction
The utility of inflammatory markers to predict readmissions and mortality in COPD cases with or without eosinophilia [Corrigendum]
Page: 417
Published online: 01 Mar 2016
CitationforThe utility of inflammatory markers to predict readmissions and mortality in COPD cases with or without eosinophilia [Corrigendum] | Full Text | PDF (103.6 KB)
  • 43 Views
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Open Access

Original Research

Article
Validity of COPD diagnoses reported through nationwide health insurance systems in the People’s Republic of China
Om P Kurmi, Julien Vaucher, Dan Xiao, Michael V Holmes, Yu Guo, Kourtney J Davis, Chen Wang, Haiyan Qin, Iain Turnbull, Peng Peng, Zheng Bian, Robert Clarke, Liming Li, Yiping Chen, Zhengming Chen & On behalf of the China Kadoorie Biobank collaborative group
Pages: 419-430
Published online: 01 Mar 2016
AbstractforValidity of COPD diagnoses reported through nationwide health insurance systems in the People’s Republic of China | Full Text | References | PDF (647.6 KB)
  • 59 Views
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Open Access
Article
Risk stratification for COPD diagnosis through an active search strategy in primary care
Pedro J Marcos, Rosa Malo de Molina & Ricard Casamor
Pages: 431-437
Published online: 01 Mar 2016
AbstractforRisk stratification for COPD diagnosis through an active search strategy in primary care | Full Text | References | PDF (368.2 KB)
  • 49 Views
  • 1 CrossRef citations
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Open Access

Review

Review Article
Striving for optimal bronchodilation: focus on olodaterol
Cristoforo Incorvaia, Marcello Montagni, Elena Makri, Gian Galeazzo Riario-Sforza & Erminia Ridolo
Pages: 439-444
Published online: 01 Mar 2016
AbstractforStriving for optimal bronchodilation: focus on olodaterol | Full Text | References | PDF (187.1 KB)
  • 49 Views
  • 3 CrossRef citations
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Open Access
Review Article
Bacterial–viral load and the immune response in stable and exacerbated COPD: significance and therapeutic prospects
Silvestro Ennio D’Anna, Bruno Balbi, Francesco Cappello, Mauro Carone & Antonino Di Stefano
Pages: 445-453
Published online: 01 Mar 2016
AbstractforBacterial–viral load and the immune response in stable and exacerbated COPD: significance and therapeutic prospects | Full Text | References | PDF (495.2 KB)
  • 83 Views
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Open Access

Original Research

Article
Incidence and outcomes of patients hospitalized with COPD exacerbation with and without pneumonia
Mette Søgaard, Morten Madsen, Anders Løkke, Ole Hilberg, Henrik Toft Sørensen & Reimar W Thomsen
Pages: 455-465
Published online: 02 Mar 2016
AbstractforIncidence and outcomes of patients hospitalized with COPD exacerbation with and without pneumonia | Full Text | References | PDF (494 KB)
  • 312 Views
  • 45 CrossRef citations
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Open Access
Article
COPD disease severity and innate immune response to pathogen-associated molecular patterns
Vincent S Fan, Sina A Gharib, Thomas R Martin & Mark M Wurfel
Pages: 467-477
Published online: 04 Mar 2016
AbstractforCOPD disease severity and innate immune response to pathogen-associated molecular patterns | Full Text | References | PDF (2.6 MB)
  • 73 Views
  • 15 CrossRef citations
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Open Access
Article
COPD assessment test and severity of airflow limitation in patients with asthma, COPD, and asthma–COPD overlap syndrome
Kazuyoshi Kurashima, Yotaro Takaku, Chie Ohta, Noboru Takayanagi, Tsutomu Yanagisawa & Yutaka Sugita
Pages: 479-487
Published online: 04 Mar 2016
AbstractforCOPD assessment test and severity of airflow limitation in patients with asthma, COPD, and asthma–COPD overlap syndrome | Full Text | References | PDF (2.2 MB)
  • 124 Views
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Open Access
Article
Whakawhanaungatanga: the importance of culturally meaningful connections to improve uptake of pulmonary rehabilitation by Māori with COPD – a qualitative study
William MM Levack, Bernadette Jones, Rebecca Grainger, Pauline Boland, Melanie Brown & Tristram R Ingham
Pages: 489-501
Published online: 09 Mar 2016
AbstractforWhakawhanaungatanga: the importance of culturally meaningful connections to improve uptake of pulmonary rehabilitation by Māori with COPD – a qualitative study | Full Text | References | PDF (367.1 KB)
  • 1082 Views
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Open Access
Article
COPD phenotypes on computed tomography and its correlation with selected lung function variables in severe patients
Silvia Maria Doria da Silva, Ilma Aparecida Paschoal, Eduardo Mello De Capitani, Marcos Mello Moreira, Luciana Campanatti Palhares & Mônica Corso Pereira
Pages: 503-513
Published online: 16 Mar 2016
AbstractforCOPD phenotypes on computed tomography and its correlation with selected lung function variables in severe patients | Full Text | References | PDF (537.2 KB)
  • 137 Views
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Open Access

Expert Opinion

Editorial
Treatment of patients with COPD and recurrent exacerbations: the role of infection and inflammation
Salud Santos, Alicia Marin, Joan Serra-Batlles, David de la Rosa, Ingrid Solanes, Xavier Pomares, Marta López-Sánchez, Mariana Muñoz-Esquerre & Marc Miravitlles
Pages: 515-525
Published online: 11 Mar 2016
AbstractforTreatment of patients with COPD and recurrent exacerbations: the role of infection and inflammation | Full Text | References | PDF (303.7 KB)
  • 267 Views
  • 33 CrossRef citations
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Open Access

Original Research

Article
Microparticles in sputum of COPD patients: a potential biomarker of the disease?
Donato Lacedonia, Giovanna Elisiana Carpagnano, Teresa Trotta, Grazia Pia Palladino, Maria Antonietta Panaro, Liugi Davide Zoppo, Maria Pia Foschino Barbaro & Chiara Porro
Pages: 527-533
Published online: 14 Mar 2016
AbstractforMicroparticles in sputum of COPD patients: a potential biomarker of the disease? | Full Text | References | PDF (635.4 KB)
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Review

Review Article
The optimum timing to wean invasive ventilation for patients with AECOPD or COPD with pulmonary infection
Yuanlin Song, Rongchang Chen, Qingyuan Zhan, Shujing Chen, Zujin Luo, Jiaxian Ou & Chen Wang
Pages: 535-542
Published online: 14 Mar 2016
AbstractforThe optimum timing to wean invasive ventilation for patients with AECOPD or COPD with pulmonary infection | Full Text | References | PDF (269.7 KB)
  • 100 Views
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Original Research

Article
Cognitive status among patients with chronic obstructive pulmonary disease
Carlos Roncero, Ana Isabel Campuzano, Jose Antonio Quintano, Jesús Molina, Joselín Pérez & Marc Miravitlles
Pages: 543-551
Published online: 16 Mar 2016
AbstractforCognitive status among patients with chronic obstructive pulmonary disease | Full Text | References | PDF (329.6 KB)
  • 129 Views
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Open Access
Article
Combining systems pharmacology, transcriptomics, proteomics, and metabolomics to dissect the therapeutic mechanism of Chinese herbal Bufei Jianpi formula for application to COPD
Peng Zhao, Liping Yang, Jiansheng Li, Ya Li, Yange Tian & Suyun Li
Pages: 553-566
Published online: 15 Mar 2016
AbstractforCombining systems pharmacology, transcriptomics, proteomics, and metabolomics to dissect the therapeutic mechanism of Chinese herbal Bufei Jianpi formula for application to COPD | Full Text | References | PDF (2.5 MB)
  • 84 Views
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Article
Relationship of airflow limitation severity with work productivity reduction and sick leave in a Japanese working population
Ayumi Onoue, Hisamitsu Omori, Takahiko Katoh, Kenichi Kubota, Yoshio Nonami, Yasuhiro Ogata & Hiromasa Inoue
Pages: 567-575
Published online: 16 Mar 2016
AbstractforRelationship of airflow limitation severity with work productivity reduction and sick leave in a Japanese working population | Full Text | References | PDF (336.1 KB)
  • 67 Views
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Article
COPD exacerbation care bundle improves standard of care, length of stay, and readmission rates
Raj Parikh, Trushil G Shah & Rajive Tandon
Pages: 577-583
Published online: 17 Mar 2016
AbstractforCOPD exacerbation care bundle improves standard of care, length of stay, and readmission rates | Full Text | References | PDF (603.9 KB)
  • 312 Views
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Article
Pharmacokinetics and safety of olodaterol administered with the Respimat Soft Mist inhaler in subjects with impaired hepatic or renal function
Christina Kunz, Doreen Luedtke, Anna Unseld, Alan Hamilton, Atef Halabi, Martina Wein & Stephan Formella
Pages: 585-595
Published online: 18 Mar 2016
AbstractforPharmacokinetics and safety of olodaterol administered with the Respimat Soft Mist inhaler in subjects with impaired hepatic or renal function | Full Text | References | PDF (911 KB)
  • 60 Views
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Article
Inhalation errors due to device switch in patients with chronic obstructive pulmonary disease and asthma: critical health and economic issues
Alessandro Roggeri, Claudio Micheletto & Daniela Paola Roggeri
Pages: 597-602
Published online: 21 Mar 2016
AbstractforInhalation errors due to device switch in patients with chronic obstructive pulmonary disease and asthma: critical health and economic issues | Full Text | References | PDF (255.5 KB)
  • 111 Views
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Article
Physical exercise is effective in preventing cigarette smoke-induced pulmonary oxidative response in mice
Renata Tiscoski Nesi, Priscila Soares de Souza, Giulia Pedroso dos Santos, Anand Thirupathi, Bruno T Menegali, Paulo Cesar Lock Silveira, Luciano Acordi da Silva, Samuel Santos Valença & Ricardo Aurino Pinho
Pages: 603-610
Published online: 22 Mar 2016
AbstractforPhysical exercise is effective in preventing cigarette smoke-induced pulmonary oxidative response in mice | Full Text | References | PDF (1.3 MB)
  • 78 Views
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Study Protocol

Article
POPE study: rationale and methodology of a study to phenotype patients with COPD in Central and Eastern Europe
Zuzana Zbozinkova, Adam Barczyk, Ruzena Tkacova, Arschang Valipour, Neven Tudoric, Kirill Zykov, Attila Somfay, Marc Miravitlles & Vladimir Koblizek
Pages: 611-622
Published online: 22 Mar 2016
AbstractforPOPE study: rationale and methodology of a study to phenotype patients with COPD in Central and Eastern Europe | Full Text | References | PDF (611.4 KB)
  • 86 Views
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Corrigendum

Correction
The Short Physical Performance Battery is a discriminative tool for identifying patients with COPD at risk of disability [Corrigendum]
Page: 623
Published online: 24 Mar 2016
CitationforThe Short Physical Performance Battery is a discriminative tool for identifying patients with COPD at risk of disability [Corrigendum] | Full Text | PDF (94.1 KB)
  • 39 Views
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Original Research

Article
COPD in primary lung cancer patients: prevalence and mortality
Elinor Ytterstad, Per C Moe & Audhild Hjalmarsen
Pages: 625-636
Published online: 23 Mar 2016
AbstractforCOPD in primary lung cancer patients: prevalence and mortality | Full Text | References | PDF (1.1 MB)
  • 85 Views
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Review

Review Article
COPD and osteoporosis: links, risks, and treatment challenges
Daisuke Inoue, Reiko Watanabe & Ryo Okazaki
Pages: 637-648
Published online: 29 Mar 2016
AbstractforCOPD and osteoporosis: links, risks, and treatment challenges | Full Text | References | PDF (275.8 KB)
  • 540 Views
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Original Research

Article
COPD advances in left ventricular diastolic dysfunction
Yoshiaki Kubota, Kuniya Asai, Koji Murai, Yayoi Tetsuou Tsukada, Hiroki Hayashi, Yoshinobu Saito, Arata Azuma, Akihiko Gemma & Wataru Shimizu
Pages: 649-655
Published online: 29 Mar 2016
AbstractforCOPD advances in left ventricular diastolic dysfunction | Full Text | References | PDF (492.1 KB)
  • 87 Views
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Article
Six-minute stepper test: a valid clinical exercise tolerance test for COPD patients
JM Grosbois, C Riquier, B Chehere, J Coquart, H Béhal, F Bart, B Wallaert & C Chenivesse
Pages: 657-663
Published online: 29 Mar 2016
AbstractforSix-minute stepper test: a valid clinical exercise tolerance test for COPD patients | Full Text | References | PDF (471.3 KB)
  • 294 Views
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Article
Predictive factors warrant screening for obstructive sleep apnea in COPD: a Taiwan National Survey
Liang-Wen Hang, Jeng-Yuan Hsu, Chee-Jen Chang, Hao-Chien Wang, Shih-Lung Cheng, Ching-Hsiung Lin, Ming-Cheng Chan, Chin-Chou Wang, Diahn-Warng Perng, Chong-Jen Yu & On behalf of the Taiwan COPD Consortium
Pages: 665-673
Published online: 30 Mar 2016
AbstractforPredictive factors warrant screening for obstructive sleep apnea in COPD: a Taiwan National Survey | Full Text | References | PDF (386.9 KB)
  • 79 Views
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Article
The effect of benzodiazepines on insomnia in patients with chronic obstructive pulmonary disease: a meta-analysis of treatment efficacy and safety
Xiao-Min Lu, Ji-Ping Zhu & Xian-Mei Zhou
Pages: 675-685
Published online: 04 Apr 2016
AbstractforThe effect of benzodiazepines on insomnia in patients with chronic obstructive pulmonary disease: a meta-analysis of treatment efficacy and safety | Full Text | References | PDF (994 KB)
  • 116 Views
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Study Protocol

Article
The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial
Kristina Vermeersch, Maria Gabrovska, Griet Deslypere, Ingel K Demedts, Hans Slabbynck, Joseph Aumann, Vincent Ninane, Geert M Verleden, Thierry Troosters, Kris Bogaerts, Guy G Brusselle, Wim Janssens & On behalf of the BACE Trial Investigators
Pages: 687-696
Published online: 31 Mar 2016
AbstractforThe Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial | Full Text | References | PDF (340.5 KB)
  • 73 Views
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Original Research

Article
COPD exacerbations by disease severity in England
Evie Merinopoulou, Mireia Raluy-Callado, Sreeram Ramagopalan, Sharon MacLachlan & Javaria Mona Khalid
Pages: 697-709
Published online: 01 Apr 2016
AbstractforCOPD exacerbations by disease severity in England | Full Text | References | PDF (489 KB)
  • 180 Views
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Article
Effects of combined training vs aerobic training on cognitive functions in COPD: a randomized controlled trial
Giovanna Aquino, Enzo Iuliano, Alessandra di Cagno, Angela Vardaro, Giovanni Fiorilli, Stefano Moffa, Alfonso Di Costanzo, Giuseppe De Simone & Giuseppe Calcagno
Pages: 711-718
Published online: 04 Apr 2016
AbstractforEffects of combined training vs aerobic training on cognitive functions in COPD: a randomized controlled trial | Full Text | References | PDF (323 KB)
  • 529 Views
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Article
A randomized, blinded study to evaluate the efficacy and safety of umeclidinium 62.5 μg compared with tiotropium 18 μg in patients with COPD
Gregory Feldman, François Maltais, Sanjeev Khindri, Mitra Vahdati-Bolouri, Alison Church, William A Fahy & Roopa Trivedi
Pages: 719-730
Published online: 07 Apr 2016
AbstractforA randomized, blinded study to evaluate the efficacy and safety of umeclidinium 62.5 μg compared with tiotropium 18 μg in patients with COPD | Full Text | References | PDF (1.2 MB)
  • 111 Views
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Article
Relationship between vitamin D-binding protein polymorphisms and blood vitamin D level in Korean patients with COPD
Youngmok Park, Young Sam Kim, Young Ae Kang, Ju Hye Shin, Yeon Mok Oh, Joon Beom Seo, Ji Ye Jung, Sang Do Lee & On behalf of the KOLD study
Pages: 731-738
Published online: 07 Apr 2016
AbstractforRelationship between vitamin D-binding protein polymorphisms and blood vitamin D level in Korean patients with COPD | Full Text | References | PDF (401.3 KB)
  • 76 Views
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Article
Does COPD risk vary by ethnicity? A retrospective cross-sectional study
Alexander Gilkes, Mark Ashworth, Peter Schofield, Timothy H Harries, Stevo Durbaba, Charlotte Weston & Patrick White
Pages: 739-746
Published online: 27 Oct 2022
AbstractforDoes COPD risk vary by ethnicity? A retrospective cross-sectional study | Full Text | References | PDF (268 KB)
  • 457 Views
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Article
Effect of inhaled drugs on anxiety and depression in patients with chronic obstructive pulmonary disease: a prospective observational study
Min Kyung Hyun, Na Rae Lee, Eun Jin Jang, Jae-Joon Yim & Chang-Hoon Lee
Pages: 747-754
Published online: 11 Apr 2016
AbstractforEffect of inhaled drugs on anxiety and depression in patients with chronic obstructive pulmonary disease: a prospective observational study | Full Text | References | PDF (412.5 KB)
  • 66 Views
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Article
Continuous quantitative measurement of the proximal airway dimensions and lung density on four-dimensional dynamic-ventilation CT in smokers
Tsuneo Yamashiro, Hiroshi Moriya, Maho Tsubakimoto, Shin Matsuoka, Sadayuki Murayama & On behalf of ACTIve Study Group
Pages: 755-764
Published online: 27 Oct 2022
AbstractforContinuous quantitative measurement of the proximal airway dimensions and lung density on four-dimensional dynamic-ventilation CT in smokers | Full Text | References | PDF (1.3 MB)
  • 61 Views
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Review

Review Article
The fissure: interlobar collateral ventilation and implications for endoscopic therapy in emphysema
Theodoor David Koster & Dirk-Jan Slebos
Pages: 765-773
Published online: 13 Apr 2016
AbstractforThe fissure: interlobar collateral ventilation and implications for endoscopic therapy in emphysema | Full Text | References | PDF (1.4 MB)
  • 123 Views
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Original Research

Article
Impacts of coexisting bronchial asthma on severe exacerbations in mild-to-moderate COPD: results from a national database
Hyun Lee, Chin Kook Rhee, Byung-Jae Lee, Dong-Chull Choi, Jee-Ae Kim, Sang Hyun Kim, Yoolwon Jeong, Tae-Hyung Kim, Gyu Rak Chon, Ki-Suck Jung, Sang Haak Lee, David Price, Kwang Ha Yoo & Hye Yun Park
Pages: 775-783
Published online: 15 Apr 2016
AbstractforImpacts of coexisting bronchial asthma on severe exacerbations in mild-to-moderate COPD: results from a national database | Full Text | References | PDF (527.6 KB)
  • 78 Views
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Review

Review Article
Dual therapy strategies for COPD: the scientific rationale for LAMA + LABA
Joshua S Cohen, Matthew C Miles, James F Donohue & Jill A Ohar
Pages: 785-797
Published online: 27 Oct 2022
AbstractforDual therapy strategies for COPD: the scientific rationale for LAMA + LABA | Full Text | References | PDF (319.9 KB)
  • 154 Views
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Original Research

Article
High-dose oral N-acetylcysteine fails to improve respiratory health status in patients with chronic obstructive pulmonary disease and chronic bronchitis: a randomized, placebo-controlled trial
Kara Johnson, Charlene E McEvoy, Sakina Naqvi, Chris Wendt, Ronald A Reilkoff, Ken M Kunisaki, Erin E Wetherbee, David Nelson, Rabindra Tirouvanziam & Dennis E Niewoehner
Pages: 799-807
Published online: 21 Apr 2016
AbstractforHigh-dose oral N-acetylcysteine fails to improve respiratory health status in patients with chronic obstructive pulmonary disease and chronic bronchitis: a randomized, placebo-controlled trial | Full Text | References | PDF (432.2 KB)
  • 115 Views
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Review

Review Article
Do telemedical interventions improve quality of life in patients with COPD? A systematic review
Thorbjørn L Gregersen, Allan Green, Ejvind Frausing, Thomas Ringbæk, Eva Brøndum & Charlotte Suppli Ulrik
Pages: 809-822
Published online: 21 Apr 2016
AbstractforDo telemedical interventions improve quality of life in patients with COPD? A systematic review | Full Text | References | PDF (348.6 KB)
  • 281 Views
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Original Research

Article
Prognostic utility of the 2011 GOLD classification and other multidimensional tools in Asian COPD patients: a prospective cohort study
Hiang Ping Chan, Amartya Mukhopadhyay, Pauline Lee Poh Chong, Sally Chin, Xue Yun Wong, Venetia Ong, Yiong Huak Chan, Tow Keang Lim & Jason Phua
Pages: 823-829
Published online: 22 Apr 2016
AbstractforPrognostic utility of the 2011 GOLD classification and other multidimensional tools in Asian COPD patients: a prospective cohort study | Full Text | References | PDF (798.6 KB)
  • 56 Views
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Article
Prevention of COPD exacerbation by lysozyme: a double-blind, randomized, placebo-controlled study
Yoshinosuke Fukuchi, Koichiro Tatsumi, Hiromasa Inoue, Yukinori Sakata, Kai Shibata, Hideaki Miyagishi, Yasuhiro Marukawa & Masakazu Ichinose
Pages: 831-838
Published online: 21 Apr 2016
AbstractforPrevention of COPD exacerbation by lysozyme: a double-blind, randomized, placebo-controlled study | Full Text | References | PDF (601 KB)
  • 71 Views
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Review

Review Article
Impact of air quality guidelines on COPD sufferers
Youcheng Liu, Shuang Yan, Karen Poh, Suyang Liu, Emanehi Iyioriobhe & David A Sterling
Pages: 839-872
Published online: 21 Apr 2016
AbstractforImpact of air quality guidelines on COPD sufferers | Full Text | References | PDF (851.9 KB)
  • 228 Views
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Original Research

Article
Prevalence of airflow limitation in subjects undergoing comprehensive health examination in Japan: Survey of Chronic Obstructive pulmonary disease Patients Epidemiology in Japan
Hisamitsu Omori, Toshihiko Kaise, Takeo Suzuki & Gerry Hagan
Pages: 873-880
Published online: 22 Apr 2016
AbstractforPrevalence of airflow limitation in subjects undergoing comprehensive health examination in Japan: Survey of Chronic Obstructive pulmonary disease Patients Epidemiology in Japan | Full Text | References | PDF (238.5 KB)
  • 57 Views
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Open Access
Article
Health behaviors and their correlates among participants in the Continuing to Confront COPD International Patient Survey
Hana Müllerová, Sarah H Landis, Zaurbek Aisanov, Kourtney J Davis, Masakazu Ichinose, David M Mannino, Joe Maskell, Ana M Menezes, Thys van der Molen, Yeon-Mok Oh, Maggie Tabberer & MeiLan K Han
Pages: 881-890
Published online: 27 Apr 2016
AbstractforHealth behaviors and their correlates among participants in the Continuing to Confront COPD International Patient Survey | Full Text | References | PDF (710.3 KB)
  • 93 Views
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Open Access
Article
Impact of tiotropium + olodaterol on physical functioning in COPD: results of an open-label observational study
Rüdiger Sauer, Michaela Hänsel, Roland Buhl, Roman A Rubin, Marcel Frey & Thomas Glaab
Pages: 891-898
Published online: 27 Apr 2016
AbstractforImpact of tiotropium + olodaterol on physical functioning in COPD: results of an open-label observational study | Full Text | References | PDF (530.7 KB)
  • 48 Views
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Article
COPD disease severity and the risk of venous thromboembolic events: a matched case–control study
Ann D Morgan, Emily Herrett, Bianca L De Stavola, Liam Smeeth & Jennifer K Quint
Pages: 899-908
Published online: 28 Apr 2016
AbstractforCOPD disease severity and the risk of venous thromboembolic events: a matched case–control study | Full Text | References | PDF (364 KB)
  • 66 Views
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Article
In vitro modeling of COPD inflammation and limitation of p38 inhibitor – SB203580
Aihong Meng, Xiaopeng Zhang, Siyu Wu, Mingxia Wu, Jing Li, Xixin Yan, Kamilla Kopec-Harding & Jiakai Wu
Pages: 909-917
Published online: 29 Apr 2016
AbstractforIn vitro modeling of COPD inflammation and limitation of p38 inhibitor – SB203580 | Full Text | References | PDF (1.1 MB)
  • 120 Views
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Article
Chronic obstructive pulmonary disease phenotypes and balance impairment
Alina Sorina Voica, Cristian Oancea, Emanuela Tudorache, Alexandru F Crisan, Ovidiu Fira-Mladinescu, Voicu Tudorache & Bogdan Timar
Pages: 919-925
Published online: 29 Apr 2016
AbstractforChronic obstructive pulmonary disease phenotypes and balance impairment | Full Text | References | PDF (415.2 KB)
  • 91 Views
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Article
Vital capacity and COPD: the Swedish CArdioPulmonary bioImage Study (SCAPIS)
Kjell Torén, Anna-Carin Olin, Anne Lindberg, Jenny Vikgren, Linus Schiöler, John Brandberg, Åse Johnsson, Gunnar Engström, H Lennart Persson, Magnus Sköld, Jan Hedner, Eva Lindberg, Andrei Malinovschi, Eeva Piitulainen, Per Wollmer, Annika Rosengren, Christer Janson, Anders Blomberg & Göran Bergström
Pages: 927-933
Published online: 02 May 2016
AbstractforVital capacity and COPD: the Swedish CArdioPulmonary bioImage Study (SCAPIS) | Full Text | References | PDF (280.2 KB)
  • 112 Views
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Article
Assisted ventilation in COPD – association between previous hospitalizations and mortality
Anne Pernille Toft-Petersen, Christian Torp-Pedersen, Ulla Møller Weinreich & Bodil Steen Rasmussen
Pages: 935-943
Published online: 03 May 2016
AbstractforAssisted ventilation in COPD – association between previous hospitalizations and mortality | Full Text | References | PDF (544.7 KB)
  • 46 Views
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Clinical Trial Report

Article
A randomized clinical trial of neurally adjusted ventilatory assist versus conventional weaning mode in patients with COPD and prolonged mechanical ventilation
Nai-Ying Kuo, Mei-Lien Tu, Tsai-Yi Hung, Shih-Feng Liu, Yu-Hsiu Chung, Meng-Chih Lin & Chao-Chien Wu
Pages: 945-951
Published online: 11 May 2016
AbstractforA randomized clinical trial of neurally adjusted ventilatory assist versus conventional weaning mode in patients with COPD and prolonged mechanical ventilation | Full Text | References | PDF (486.4 KB)
  • 98 Views
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Original Research

Article
Quantitative computed tomography measurements of emphysema for diagnosing asthma-chronic obstructive pulmonary disease overlap syndrome
Mengshuang Xie, Wei Wang, Shuang Dou, Liwei Cui & Wei Xiao
Pages: 953-961
Published online: 06 May 2016
AbstractforQuantitative computed tomography measurements of emphysema for diagnosing asthma-chronic obstructive pulmonary disease overlap syndrome | Full Text | References | PDF (261 KB)
  • 63 Views
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Article
Assessment of illness acceptance by patients with COPD and the prevalence of depression and anxiety in COPD
Izabella Uchmanowicz, Beata Jankowska-Polanska, Urszula Motowidlo, Bartosz Uchmanowicz & Mariusz Chabowski
Pages: 963-970
Published online: 09 May 2016
AbstractforAssessment of illness acceptance by patients with COPD and the prevalence of depression and anxiety in COPD | Full Text | References | PDF (318.7 KB)
  • 369 Views
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Article
A randomized, parallel-group study to evaluate the efficacy of umeclidinium/vilanterol 62.5/25 μg on health-related quality of life in patients with COPD
Thomas M Siler, Alison C Donald, Dianne O’Dell, Alison Church & William A Fahy
Pages: 971-979
Published online: 09 May 2016
AbstractforA randomized, parallel-group study to evaluate the efficacy of umeclidinium/vilanterol 62.5/25 μg on health-related quality of life in patients with COPD | Full Text | References | PDF (812.7 KB)
  • 61 Views
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Article
Follow-up study on management of chronic obstructive pulmonary disease in Hunan Province, the People’s Republic of China
Yuqin Zeng, Jianxian Xu, Shan Cai, Fen Jiang, Anmei Hu, Huayun Liu, Chengli Bei & Ping Chen
Pages: 981-989
Published online: 10 May 2016
AbstractforFollow-up study on management of chronic obstructive pulmonary disease in Hunan Province, the People’s Republic of China | Full Text | References | PDF (593.4 KB)
  • 52 Views
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Article
Comparison of pulmonary function in patients with COPD, asthma-COPD overlap syndrome, and asthma with airflow limitation
Yoshiaki Kitaguchi, Masanori Yasuo & Masayuki Hanaoka
Pages: 991-997
Published online: 09 May 2016
AbstractforComparison of pulmonary function in patients with COPD, asthma-COPD overlap syndrome, and asthma with airflow limitation | Full Text | References | PDF (338.6 KB)
  • 145 Views
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Article
Diagnosis of alpha-1 antitrypsin deficiency: a population-based study
Miriam Barrecheguren, Mónica Monteagudo, Pere Simonet, Carl Llor, Esther Rodriguez, Jaume Ferrer, Cristina Esquinas & Marc Miravitlles
Pages: 999-1004
Published online: 10 May 2016
AbstractforDiagnosis of alpha-1 antitrypsin deficiency: a population-based study | Full Text | References | PDF (482 KB)
  • 207 Views
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Article
Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation
Britt-Marie Sundblad, Jie Ji, Bettina Levänen, Klara Midander, Anneli Julander, Kjell Larsson, Lena Palmberg & Anders Lindén
Pages: 1005-1013
Published online: 11 May 2016
AbstractforExtracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation | Full Text | References | PDF (484.4 KB)
  • 79 Views
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Article
Left ventricular structure and remodeling in patients with COPD
Giovanna Pelà, Mauro Li Calzi, Silvana Pinelli, Roberta Andreoli, Nicola Sverzellati, Giuseppina Bertorelli, Matteo Goldoni & Alfredo Chetta
Pages: 1015-1022
Published online: 27 Oct 2022
AbstractforLeft ventricular structure and remodeling in patients with COPD | Full Text | References | PDF (259.5 KB)
  • 79 Views
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Article
A comparison of synchronized intermittent mandatory ventilation and pressure-regulated volume control ventilation in elderly patients with acute exacerbations of COPD and respiratory failure
Suchi Chang, Jindong Shi, Cuiping Fu, Xu Wu & Shanqun Li
Pages: 1023-1029
Published online: 17 May 2016
AbstractforA comparison of synchronized intermittent mandatory ventilation and pressure-regulated volume control ventilation in elderly patients with acute exacerbations of COPD and respiratory failure | Full Text | References | PDF (508 KB)
  • 127 Views
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Corrigendum

Correction
Triple therapy with salmeterol/fluticasone propionate 50/250 plus tiotropium bromide improve lung function versus individual treatments in moderate-to-severe Japanese COPD patients: a randomized controlled trial – Evaluation of Airway sGaw after treatment with tripLE [Corrigendum]
Pages: 1031-1033
Published online: 18 May 2016
First Page PreviewforTriple therapy with salmeterol/fluticasone propionate 50/250 plus tiotropium bromide improve lung function versus individual treatments in moderate-to-severe Japanese COPD patients: a randomized controlled trial – Evaluation of Airway sGaw after treatment with tripLE [Corrigendum] | Full Text | PDF (398.1 KB)
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Original Research

Article
Effects of budesonide on toll-like receptor expression in alveolar macrophages from smokers with and without COPD
Jie Ji, Ida von Schéele, Bo Billing, Barbro Dahlén, Ann-Sofie Lantz, Kjell Larsson & Lena Palmberg
Pages: 1035-1043
Published online: 17 May 2016
AbstractforEffects of budesonide on toll-like receptor expression in alveolar macrophages from smokers with and without COPD | Full Text | References | PDF (642.9 KB)
  • 58 Views
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Open Access
Article
Investigating sensitivity, specificity, and area under the curve of the Clinical COPD Questionnaire, COPD Assessment Test, and Modified Medical Research Council scale according to GOLD using St George’s Respiratory Questionnaire cutoff 25 (and 20) as reference
Ioanna G Tsiligianni, Harma J Alma, Corina de Jong, Danijel Jelusic, Michael Wittmann, Michael Schuler, Konrad Schultz, Boudewijn J Kollen, Thys van der Molen & Janwillem WH Kocks
Pages: 1045-1052
Published online: 18 May 2016
AbstractforInvestigating sensitivity, specificity, and area under the curve of the Clinical COPD Questionnaire, COPD Assessment Test, and Modified Medical Research Council scale according to GOLD using St George’s Respiratory Questionnaire cutoff 25 (and 20) as reference | Full Text | References | PDF (665.9 KB)
  • 260 Views
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Article
Hyperlipidemia in COPD is associated with decreased incidence of pneumonia and mortality: a nationwide health insurance data-based retrospective cohort study
Ming-Chen Chan, Ching-Heng Lin & Yu Ru Kou
Pages: 1053-1059
Published online: 18 May 2016
AbstractforHyperlipidemia in COPD is associated with decreased incidence of pneumonia and mortality: a nationwide health insurance data-based retrospective cohort study | Full Text | References | PDF (359.5 KB)
  • 128 Views
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Article
COPD promotes migration of A549 lung cancer cells: the role of chemokine CCL21
Barbara Kuźnar-Kamińska, Justyna Mikuła-Pietrasik, Patrycja Sosińska, Krzysztof Książek & Halina Batura-Gabryel
Pages: 1061-1066
Published online: 20 May 2016
AbstractforCOPD promotes migration of A549 lung cancer cells: the role of chemokine CCL21 | Full Text | References | PDF (602.3 KB)
  • 103 Views
  • 6 CrossRef citations
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Review

Review Article
Acute oxygen therapy: a review of prescribing and delivery practices
Joyce L Cousins, Peter AB Wark & Vanessa M McDonald
Pages: 1067-1075
Published online: 24 May 2016
AbstractforAcute oxygen therapy: a review of prescribing and delivery practices | Full Text | References | PDF (775.6 KB)
  • 1435 Views
  • 16 CrossRef citations
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Original Research

Article
Nasal highflow improves ventilation in patients with COPD
Jens Bräunlich, Marcus Köhler & Hubert Wirtz
Pages: 1077-1085
Published online: 25 May 2016
AbstractforNasal highflow improves ventilation in patients with COPD | Full Text | References | PDF (1.2 MB)
  • 219 Views
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Open Access
Article
Are interstitial lung abnormalities associated with COPD? A nested case–control study
Francesca Bozzetti, Ilaria Paladini, Enrico Rabaiotti, Alessandro Franceschini, Veronica Alfieri, Alfredo Chetta, Ernesto Crisafulli, Mario Silva, Ugo Pastorino & Nicola Sverzellati
Pages: 1087-1096
Published online: 26 May 2016
AbstractforAre interstitial lung abnormalities associated with COPD? A nested case–control study | Full Text | References | PDF (2.1 MB)
  • 80 Views
  • 10 CrossRef citations
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Open Access
Article
Symptoms and lung function decline in a middle-aged cohort of males and females in Australia
Michael J Abramson, Sonia Kaushik, Geza P Benke, Brigitte M Borg, Catherine L Smith, Shyamali C Dharmage & Bruce R Thompson
Pages: 1097-1103
Published online: 26 May 2016
AbstractforSymptoms and lung function decline in a middle-aged cohort of males and females in Australia | Full Text | References | PDF (458.8 KB)
  • 72 Views
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Article
Accuracy of forced oscillation technique to assess lung function in geriatric COPD population
Hoi Nam Tse, Cee Zhung Steven Tseng, King Ying Wong, Kwok Sang Yee & Lai Yun Ng
Pages: 1105-1118
Published online: 26 May 2016
AbstractforAccuracy of forced oscillation technique to assess lung function in geriatric COPD population | Full Text | References | PDF (2.6 MB)
  • 95 Views
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Article
Resolvin D1 prevents smoking-induced emphysema and promotes lung tissue regeneration
Kang-Hyun Kim, Tai Sun Park, You-Sun Kim, Jae Seung Lee, Yeon-Mok Oh, Sang-Do Lee & Sei Won Lee
Pages: 1119-1128
Published online: 27 May 2016
AbstractforResolvin D1 prevents smoking-induced emphysema and promotes lung tissue regeneration | Full Text | References | PDF (4.7 MB)
  • 79 Views
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Open Access
Article
Relationship between plasma matrix metalloproteinase levels, pulmonary function, bronchodilator response, and emphysema severity
Hyeon-Kyoung Koo, Yoonki Hong, Myoung Nam Lim, Jae-Joon Yim & Woo Jin Kim
Pages: 1129-1137
Published online: 27 May 2016
AbstractforRelationship between plasma matrix metalloproteinase levels, pulmonary function, bronchodilator response, and emphysema severity | Full Text | References | PDF (827.7 KB)
  • 61 Views
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Article
Asthma-chronic obstructive pulmonary disease overlap syndrome in the urban Chinese population: prevalence and disease burden using the 2010, 2012, and 2013 China National Health and Wellness Surveys
Bo Ding, Marco DiBonaventura, Niklas Karlsson & Xia Ling
Pages: 1139-1150
Published online: 09 Jun 2016
AbstractforAsthma-chronic obstructive pulmonary disease overlap syndrome in the urban Chinese population: prevalence and disease burden using the 2010, 2012, and 2013 China National Health and Wellness Surveys | Full Text | References | PDF (364.1 KB)
  • 91 Views
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Article
Can patients with moderate to severe acute respiratory failure from COPD be treated safely with noninvasive mechanical ventilation on the ward?
Murat Yalcinsoy, Cuneyt Salturk, Selahattin Oztas, Sinem Gungor, Ipek Ozmen, Feyyaz Kabadayi, Aysem Askim Oztim, Emine Aksoy, Nalan Adıguzel, Ozlem Oruc & Zuhal Karakurt
Pages: 1151-1160
Published online: 31 May 2016
AbstractforCan patients with moderate to severe acute respiratory failure from COPD be treated safely with noninvasive mechanical ventilation on the ward? | Full Text | References | PDF (668.1 KB)
  • 78 Views
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Article
Can a supported self-management program for COPD upon hospital discharge reduce readmissions? A randomized controlled trial
Vicki Johnson-Warrington, Karen Rees, Colin Gelder, Mike D Morgan & Sally J Singh
Pages: 1161-1169
Published online: 02 Jun 2016
AbstractforCan a supported self-management program for COPD upon hospital discharge reduce readmissions? A randomized controlled trial | Full Text | References | PDF (737.5 KB)
  • 276 Views
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Article
Determinants for changing the treatment of COPD: a regression analysis from a clinical audit
Jose Luis López-Campos, María Abad Arranz, Carmen Calero Acuña, Fernando Romero Valero, Ruth Ayerbe García, Antonio Hidalgo Molina, Ricardo I Aguilar Perez-Grovas, Francisco García Gil, Francisco Casas Maldonado, Laura Caballero Ballesteros, María Sánchez Palop, Dolores Pérez-Tejero, Alejandro Segado, Jose Calvo Bonachera, Bárbara Hernández Sierra, Adolfo Doménech, Macarena Arroyo Varela, Francisco González Vargas & Juan J Cruz Rueda
Pages: 1171-1178
Published online: 02 Jun 2016
AbstractforDeterminants for changing the treatment of COPD: a regression analysis from a clinical audit | Full Text | References | PDF (236.3 KB)
  • 61 Views
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Review

Review Article
Action plans for COPD: strategies to manage exacerbations and improve outcomes
Leena Jalota & Vipul V Jain
Pages: 1179-1188
Published online: 02 Jun 2016
AbstractforAction plans for COPD: strategies to manage exacerbations and improve outcomes | Full Text | References | PDF (407.5 KB)
  • 328 Views
  • 6 CrossRef citations
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Original Research

Article
Home-based neuromuscular electrical stimulation improves exercise tolerance and health-related quality of life in patients with COPD
Jérémy B Coquart, Jean-Marie Grosbois, Cecile Olivier, Frederic Bart, Ingrid Castres & Benoit Wallaert
Pages: 1189-1197
Published online: 03 Jun 2016
AbstractforHome-based neuromuscular electrical stimulation improves exercise tolerance and health-related quality of life in patients with COPD | Full Text | References | PDF (420.2 KB)
  • 89 Views
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Article
Development of a Barthel Index based on dyspnea for patients with respiratory diseases
Michele Vitacca, Mara Paneroni, Paola Baiardi, Vito De Carolis, Elisabetta Zampogna, Stefano Belli, Mauro Carone, Antonio Spanevello, Bruno Balbi & Giorgio Bertolotti
Pages: 1199-1206
Published online: 07 Jun 2016
AbstractforDevelopment of a Barthel Index based on dyspnea for patients with respiratory diseases | Full Text | References | PDF (650.1 KB)
  • 263 Views
  • 33 CrossRef citations
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Article
Smokers with emphysema and small airway disease on computed tomography have lower bone density
Esther Pompe, Pim A de Jong, Eva M van Rikxoort, Leticia Gallardo Estrella, Werner U de Jong, Rozemarijn Vliegenthart, Matthijs Oudkerk, Carlijn M van der Aalst, Bram van Ginneken, Jan-Willem J Lammers & Firdaus AA Mohamed Hoesein
Pages: 1207-1216
Published online: 08 Jun 2016
AbstractforSmokers with emphysema and small airway disease on computed tomography have lower bone density | Full Text | References | PDF (2.3 MB)
  • 58 Views
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Article
Agreement between a simple dyspnea-guided treatment algorithm for stable COPD and the GOLD guidelines: a pilot study
Carlos Cabrera, Ciro Casanova, Yolanda Martín, Virginia Mirabal, María del Carmen Sánchez, Felisa Álvarez, Gabriel Juliá, Pedro Cabrera-Navarro, Miguel Ángel García-Bello, José María Marín, Juan Pablo de-Torres, Miguel Divo & Bartolomé Celli
Pages: 1217-1222
Published online: 08 Jun 2016
AbstractforAgreement between a simple dyspnea-guided treatment algorithm for stable COPD and the GOLD guidelines: a pilot study | Full Text | References | PDF (595.5 KB)
  • 61 Views
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Article
Prompt initiation of maintenance treatment following a COPD exacerbation: outcomes in a large insured population
Anna D Coutinho, Tasneem Lokhandwala, Robert L Boggs, Anand A Dalal, Pamela B Landsman-Blumberg, Julie Priest & David A Stempel
Pages: 1223-1231
Published online: 08 Jun 2016
AbstractforPrompt initiation of maintenance treatment following a COPD exacerbation: outcomes in a large insured population | Full Text | References | PDF (750.1 KB)
  • 55 Views
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Article
Efficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study
Craig LaForce, Gregory Feldman, Selwyn Spangenthal, Joerg H Eckert, Michelle Henley, Francesco Patalano & Peter D’Andrea
Pages: 1233-1243
Published online: 08 Jun 2016
AbstractforEfficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study | Full Text | References | PDF (1.2 MB)
  • 69 Views
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Article
Lung perfusion and emphysema distribution affect the outcome of endobronchial valve therapy
Christian Thomsen, Dorothea Theilig, Dominik Herzog, Alexander Poellinger, Felix Doellinger, Nils Schreiter, Vera Schreiter, Dirk Schürmann, Bettina Temmesfeld-Wollbrueck, Stefan Hippenstiel, Norbert Suttorp & Ralf-Harto Hubner
Pages: 1245-1259
Published online: 27 Oct 2022
AbstractforLung perfusion and emphysema distribution affect the outcome of endobronchial valve therapy | Full Text | References | PDF (1.7 MB)
  • 81 Views
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Article
Impact of combined pulmonary fibrosis and emphysema on surgical complications and long-term survival in patients undergoing surgery for non-small-cell lung cancer
Atsushi Hata, Yasuo Sekine, Ohashi Kota, Eitetsu Koh & Ichiro Yoshino
Pages: 1261-1268
Published online: 09 Jun 2016
AbstractforImpact of combined pulmonary fibrosis and emphysema on surgical complications and long-term survival in patients undergoing surgery for non-small-cell lung cancer | Full Text | References | PDF (588.2 KB)
  • 55 Views
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Open Access
Article
Impact of mild exacerbation on COPD symptoms in a Japanese cohort
Minako Sato, Shotaro Chubachi, Mamoru Sasaki, Mizuha Haraguchi, Naofumi Kameyama, Akihiro Tsutsumi, Saeko Takahashi, Hidetoshi Nakamura, Koichiro Asano & Tomoko Betsuyaku
Pages: 1269-1278
Published online: 09 Jun 2016
AbstractforImpact of mild exacerbation on COPD symptoms in a Japanese cohort | Full Text | References | PDF (933.9 KB)
  • 102 Views
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Article
α1-Antitrypsin reduces rhinovirus infection in primary human airway epithelial cells exposed to cigarette smoke
Reena Berman, Di Jiang, Qun Wu & Hong Wei Chu
Pages: 1279-1286
Published online: 10 Jun 2016
Abstractforα1-Antitrypsin reduces rhinovirus infection in primary human airway epithelial cells exposed to cigarette smoke | Full Text | References | PDF (869.3 KB)
  • 60 Views
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Article
Depression symptoms reduce physical activity in COPD patients: a prospective multicenter study
Iván Dueñas-Espín, Heleen Demeyer, Elena Gimeno-Santos, Michael I Polkey, Nicholas S Hopkinson, Roberto A Rabinovich, Fabienne Dobbels, Niklas Karlsson, Thierry Troosters, Judith Garcia-Aymerich & On behalf of the PROactive Consortium
Pages: 1287-1295
Published online: 27 Oct 2022
AbstractforDepression symptoms reduce physical activity in COPD patients: a prospective multicenter study | Full Text | References | PDF (537.1 KB)
  • 246 Views
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Review

Review Article
The asthma–COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway disease?
Konstantinos Kostikas, Andreas Clemens & Francesco Patalano
Pages: 1297-1306
Published online: 16 Jun 2016
AbstractforThe asthma–COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway disease? | Full Text | References | PDF (756 KB)
  • 57 Views
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Original Research

Article
Changes in respiratory function impairment following the treatment of severe pulmonary tuberculosis – limitations for the underlying COPD detection
Milan Radovic, Lidija Ristic, Zorica Ciric, Violeta Dinic-Radovic, Ivana Stankovic, Tatjana Pejcic, Milan Rancic & Dragan Bogdanovic
Pages: 1307-1316
Published online: 16 Jun 2016
AbstractforChanges in respiratory function impairment following the treatment of severe pulmonary tuberculosis – limitations for the underlying COPD detection | Full Text | References | PDF (557.5 KB)
  • 95 Views
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Article
Prevalence of and risk factors for postoperative pulmonary complications after lung cancer surgery in patients with early-stage COPD
Eun Sun Kim, Young Tae Kim, Chang Hyun Kang, In Kyu Park, Won Bae, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Young Whan Kim, Sung Koo Han & Chul-Gyu Yoo
Pages: 1317-1326
Published online: 16 Jun 2016
AbstractforPrevalence of and risk factors for postoperative pulmonary complications after lung cancer surgery in patients with early-stage COPD | Full Text | References | PDF (358.2 KB)
  • 220 Views
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Article
Factors associated with exacerbation in mild- to-moderate COPD patients
Joo Kyung Kim, Soo Haeng Lee, Bho Hyeon Lee, Chang Youl Lee, Do Jin Kim, Kyung Hoon Min, Sung Kyoung Kim, Kwang Ha Yoo, Ki-Suck Jung & Yong Il Hwang
Pages: 1327-1333
Published online: 16 Jun 2016
AbstractforFactors associated with exacerbation in mild- to-moderate COPD patients | Full Text | References | PDF (671.7 KB)
  • 99 Views
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Article
Chronic bronchitis is an independently associated factor for more symptom and high-risk groups
Joon Young Choi, Hyoung Kyu Yoon, Seoung Ju Park, Yong Bum Park, Kyeong-Cheol Shin, Ju Ock Na, Kwang Ha Yoo, Ki-Suck Jung, Young Kyoon Kim & Chin Kook Rhee
Pages: 1335-1341
Published online: 21 Jun 2016
AbstractforChronic bronchitis is an independently associated factor for more symptom and high-risk groups | Full Text | References | PDF (604.6 KB)
  • 78 Views
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Article
The impact of coping on the somatic and mental status of patients with COPD: a cross-sectional study
Ion Papava, Cristian Oancea, Virgil Radu Enatescu, Ana Cristina Bredicean, Liana Dehelean, Radu Stefan Romosan & Bogdan Timar
Pages: 1343-1351
Published online: 27 Oct 2022
AbstractforThe impact of coping on the somatic and mental status of patients with COPD: a cross-sectional study | Full Text | References | PDF (657.9 KB)
  • 140 Views
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Article
Immediate effect of manual therapy on respiratory functions and inspiratory muscle strength in patients with COPD
Gul Deniz Yilmaz Yelvar, Yasemin Çirak, Yasemin Parlak Demir, Murat Dalkilinç & Bülent Bozkurt
Pages: 1353-1357
Published online: 20 Jun 2016
AbstractforImmediate effect of manual therapy on respiratory functions and inspiratory muscle strength in patients with COPD | Full Text | References | PDF (303.1 KB)
  • 557 Views
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Article
Vitamin D should be supplemented more actively in elderly patients with coronary heart disease combined with COPD
Ling Zhang & Qiao-ying Yuan
Pages: 1359-1365
Published online: 21 Jun 2016
AbstractforVitamin D should be supplemented more actively in elderly patients with coronary heart disease combined with COPD | Full Text | References | PDF (954.8 KB)
  • 57 Views
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Review

Review Article
Association between TNF-α −308 G/A polymorphism and COPD susceptibility: a meta-analysis update
Lu Zhang, Hao Gu, Yihang Gu & Xiaoning Zeng
Pages: 1367-1379
Published online: 22 Jun 2016
AbstractforAssociation between TNF-α −308 G/A polymorphism and COPD susceptibility: a meta-analysis update | Full Text | References | PDF (1 MB)
  • 60 Views
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Original Research

Article
Point-of-care procalcitonin test to reduce antibiotic exposure in patients hospitalized with acute exacerbation of COPD
Caspar Corti, Markus Fally, Andreas Fabricius-Bjerre, Katrine Mortensen, Birgitte Nybo Jensen, Helle F Andreassen, Celeste Porsbjerg, Jenny Dahl Knudsen & Jens-Ulrik Jensen
Pages: 1381-1389
Published online: 22 Jun 2016
AbstractforPoint-of-care procalcitonin test to reduce antibiotic exposure in patients hospitalized with acute exacerbation of COPD | Full Text | References | PDF (565.6 KB)
  • 119 Views
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Review

Review Article
Lung inflammation caused by inhaled toxicants: a review
John Wong, Bruce E Magun & Lisa J Wood
Pages: 1391-1401
Published online: 23 Jun 2016
AbstractforLung inflammation caused by inhaled toxicants: a review | Full Text | References | PDF (592.5 KB)
  • 496 Views
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Original Research

Article
Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD
Yasuhiro Yamauchi, Hideo Yasunaga, Wakae Hasegawa, Yukiyo Sakamoto, Hideyuki Takeshima, Taisuke Jo, Hiroki Matsui, Kiyohide Fushimi & Takahide Nagase
Pages: 1403-1411
Published online: 23 Jun 2016
AbstractforEffect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD | Full Text | References | PDF (312.5 KB)
  • 49 Views
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Article
Prevention of clinically important deteriorations in COPD with umeclidinium/vilanterol
Dave Singh, M Reza Maleki-Yazdi, Lee Tombs, Ahmar Iqbal, William A Fahy & Ian Naya
Pages: 1413-1424
Published online: 24 Jun 2016
AbstractforPrevention of clinically important deteriorations in COPD with umeclidinium/vilanterol | Full Text | References | PDF (904 KB)
  • 97 Views
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Open Access
Article
Early bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING)
Jose M Marin, Kai M Beeh, Andreas Clemens, Walter Castellani, Lennart Schaper, Dinesh Saralaya, Anthony Gunstone, Ricard Casamor, Konstantinos Kostikas & Maryam Aalamian-Mattheis
Pages: 1425-1434
Published online: 28 Jun 2016
AbstractforEarly bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING) | Full Text | References | PDF (676.8 KB)
  • 81 Views
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Article
Morphological changes in small pulmonary vessels are associated with severe acute exacerbation in chronic obstructive pulmonary disease
Katsuhiro Yoshimura, Yuzo Suzuki, Tomohiro Uto, Jun Sato, Shiro Imokawa & Takafumi Suda
Pages: 1435-1445
Published online: 28 Jun 2016
AbstractforMorphological changes in small pulmonary vessels are associated with severe acute exacerbation in chronic obstructive pulmonary disease | Full Text | References | PDF (1.3 MB)
  • 48 Views
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Article
An international randomized study of a home-based self-management program for severe COPD: the COMET
Jean Bourbeau, Pere Casan, Silvia Tognella, Peter Haidl, Joëlle B Texereau, Romain Kessler & On behalf of the COMET investigators
Pages: 1447-1451
Published online: 28 Jun 2016
AbstractforAn international randomized study of a home-based self-management program for severe COPD: the COMET | Full Text | References | PDF (320.3 KB)
  • 116 Views
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Open Access
Article
A new diagnosis of asthma or COPD is linked to smoking cessation – the Tromsø study
Signe Elise Danielsen, Maja-Lisa Løchen, Astri Medbø, Monica Linea Vold & Hasse Melbye
Pages: 1453-1458
Published online: 30 Jun 2016
AbstractforA new diagnosis of asthma or COPD is linked to smoking cessation – the Tromsø study | Full Text | References | PDF (436.7 KB)
  • 76 Views
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Article
Pulmonary effects of active smoking and secondhand smoke exposure among adolescent students in Juárez, Mexico
Yelena Bird & Hugo Staines-Orozco
Pages: 1459-1467
Published online: 29 Jun 2016
AbstractforPulmonary effects of active smoking and secondhand smoke exposure among adolescent students in Juárez, Mexico | Full Text | References | PDF (258.9 KB)
  • 324 Views
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Article
Efficacy and safety of ipratropium bromide/salbutamol sulphate administered in a hydrofluoroalkane metered-dose inhaler for the treatment of COPD
Amal Bhattacharya, Salil Bhargava, Virendra Singh, Deepak Talwar, Jagdeep Whig, Juliet Rebello, Shrinivas Purandare & Jaideep Gogtay
Pages: 1469-1476
Published online: 30 Jun 2016
AbstractforEfficacy and safety of ipratropium bromide/salbutamol sulphate administered in a hydrofluoroalkane metered-dose inhaler for the treatment of COPD | Full Text | References | PDF (356.3 KB)
  • 72 Views
  • 1 CrossRef citations
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Review

Review Article
Potential treatment benefits and safety of roflumilast in COPD: a systematic review and meta-analysis
Lianfang Yuan, Xuan Dai, Meng Yang, Qiling Cai & Na Shao
Pages: 1477-1483
Published online: 30 Jun 2016
AbstractforPotential treatment benefits and safety of roflumilast in COPD: a systematic review and meta-analysis | Full Text | References | PDF (645.8 KB)
  • 139 Views
  • 21 CrossRef citations
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Original Research

Article
Reduced sputum expression of interferon-stimulated genes in severe COPD
Clarissa Hilzendeger, Jane da Silva, Monique Henket, Florence Schleich, Jean Louis Corhay, Tatiana Kebadze, Michael R Edwards, Patrick Mallia, Sebastian L Johnston & Renaud Louis
Pages: 1485-1494
Published online: 30 Jun 2016
AbstractforReduced sputum expression of interferon-stimulated genes in severe COPD | Full Text | References | PDF (667 KB)
  • 71 Views
  • 14 CrossRef citations
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Article
Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD
Netsanet A Negewo, Vanessa M McDonald, Katherine J Baines, Peter AB Wark, Jodie L Simpson, Paul W Jones & Peter G Gibson
Pages: 1495-1504
Published online: 01 Jul 2016
AbstractforPeripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD | Full Text | References | PDF (794.6 KB)
  • 185 Views
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Article
Relationship between balance and physical activity measured by an activity monitor in elderly COPD patients
Masahiro Iwakura, Kazuki Okura, Kazuyuki Shibata, Atsuyoshi Kawagoshi, Keiyu Sugawara, Hitomi Takahashi & Takanobu Shioya
Pages: 1505-1514
Published online: 01 Jul 2016
AbstractforRelationship between balance and physical activity measured by an activity monitor in elderly COPD patients | Full Text | References | PDF (656.4 KB)
  • 220 Views
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Article
Characteristics of elderly patients with COPD and newly diagnosed lung cancer, and factors associated with treatment decision
Jianwen Qin, Guangsheng Li & Jingmin Zhou
Pages: 1515-1520
Published online: 04 Jul 2016
AbstractforCharacteristics of elderly patients with COPD and newly diagnosed lung cancer, and factors associated with treatment decision | Full Text | References | PDF (255.8 KB)
  • 45 Views
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Article
Smoking-related interstitial fibrosis combined with pulmonary emphysema: computed tomography-pathologic correlative study using lobectomy specimens
Hideji Otani, Tomonori Tanaka, Kiyoshi Murata, Junya Fukuoka, Norihisa Nitta, Yukihiro Nagatani, Akinaga Sonoda & Masashi Takahashi
Pages: 1521-1532
Published online: 04 Jul 2016
AbstractforSmoking-related interstitial fibrosis combined with pulmonary emphysema: computed tomography-pathologic correlative study using lobectomy specimens | Full Text | References | PDF (5.8 MB)
  • 74 Views
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Clinical Trial Report

Article
Pulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension
Bita Hajian, Jan De Backer, Wim Vos, Cedric Van Holsbeke, Francisca Ferreira, Deborah A Quinn, Annemie Hufkens, Rita Claes & Wilfried De Backer
Pages: 1533-1541
Published online: 05 Jul 2016
AbstractforPulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension | Full Text | References | PDF (2.2 MB)
  • 129 Views
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Original Research

Article
The COPD assessment test and St George’s Respiratory Questionnaire: are they equivalent in subjects with COPD?
Mariko Morishita-Katsu, Koichi Nishimura, Hiroyuki Taniguchi, Tomoki Kimura, Yasuhiro Kondoh, Kensuke Kataoka, Tomoya Ogawa, Fumiko Watanabe, Shinichi Arizono, Osamu Nishiyama, Kazuhito Nakayasu, Kazuyoshi Imaizumi & Yoshinori Hasegawa
Pages: 1543-1551
Published online: 07 Jul 2016
AbstractforThe COPD assessment test and St George’s Respiratory Questionnaire: are they equivalent in subjects with COPD? | Full Text | References | PDF (577.7 KB)
  • 145 Views
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Review

Review Article
Brazilian studies on pulmonary function in COPD patients: what are the gaps?
Agnaldo José Lopes & Pedro Lopes de Melo
Pages: 1553-1567
Published online: 11 Jul 2016
AbstractforBrazilian studies on pulmonary function in COPD patients: what are the gaps? | Full Text | References | PDF (851.2 KB)
  • 59 Views
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Original Research

Article
Associations of autophagy with lung diffusion capacity and oxygen saturation in severe COPD: effects of particulate air pollution
Kang-Yun Lee, Ling-Ling Chiang, Shu-Chuan Ho, Wen-Te Liu, Tzu-Tao Chen, Po-Hao Feng, Chien-Ling Su, Kai-Jen Chuang, Chih-Cheng Chang & Hsiao-Chi Chuang
Pages: 1569-1578
Published online: 27 Oct 2022
AbstractforAssociations of autophagy with lung diffusion capacity and oxygen saturation in severe COPD: effects of particulate air pollution | Full Text | References | PDF (1 MB)
  • 68 Views
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Commentary

Article Commentary
Acute exacerbation of COPD: is it the “stroke of the lungs”?
Georgios Hillas, Fotis Perlikos & Nikolaos Tzanakis
Pages: 1579-1586
Published online: 13 Jul 2016
AbstractforAcute exacerbation of COPD: is it the “stroke of the lungs”? | Full Text | References | PDF (465.4 KB)
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Review

Review Article
Involvement of informal caregivers in supporting patients with COPD: a review of intervention studies
Jamie Bryant, Elise Mansfield, Allison W Boyes, Amy Waller, Rob Sanson-Fisher & Timothy Regan
Pages: 1587-1596
Published online: 14 Jul 2016
AbstractforInvolvement of informal caregivers in supporting patients with COPD: a review of intervention studies | Full Text | References | PDF (345.8 KB)
  • 308 Views
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Original Research

Article
Phenotypic assessment of pulmonary hypertension using high-resolution echocardiography is feasible in neonatal mice with experimental bronchopulmonary dysplasia and pulmonary hypertension: a step toward preventing chronic obstructive pulmonary disease
Corey L Reynolds, Shaojie Zhang, Amrit Kumar Shrestha, Roberto Barrios & Binoy Shivanna
Pages: 1597-1605
Published online: 14 Jul 2016
AbstractforPhenotypic assessment of pulmonary hypertension using high-resolution echocardiography is feasible in neonatal mice with experimental bronchopulmonary dysplasia and pulmonary hypertension: a step toward preventing chronic obstructive pulmonary disease | Full Text | References | PDF (2.8 MB)
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Article
Inhaled corticosteroids can reduce osteoporosis in female patients with COPD
Shih-Feng Liu, Ho-Chang Kuo, Guan-Heng Liu, Shu-Chen Ho, Huang-Chih Chang, Hung-Tu Huang, Yu-Mu Chen, Kuo-Tung Huang, Kuan-Yi Chen, Wen-Feng Fang & Meng-Chih Lin
Pages: 1607-1614
Published online: 14 Jul 2016
AbstractforInhaled corticosteroids can reduce osteoporosis in female patients with COPD | Full Text | References | PDF (500.4 KB)
  • 77 Views
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Article
Effects of biomass smoke on pulmonary functions: a case control study
Baran Balcan, Selcuk Akan, Aylin Ozsancak Ugurlu, Bahar Ozcelik Handemir, Berrin Bagcı Ceyhan & Sevket Ozkaya
Pages: 1615-1622
Published online: 19 Jul 2016
AbstractforEffects of biomass smoke on pulmonary functions: a case control study | Full Text | References | PDF (1.2 MB)
  • 108 Views
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Article
The differential effects of inspiratory, expiratory, and combined resistive breathing on healthy lung
Konstantinos Loverdos, Dimitrios Toumpanakis, Eleni Litsiou, Vassiliki Karavana, Constantinos Glynos, Christina Magkou, Stamatios Theocharis & Theodoros Vassilakopoulos
Pages: 1623-1638
Published online: 19 Jul 2016
AbstractforThe differential effects of inspiratory, expiratory, and combined resistive breathing on healthy lung | Full Text | References | PDF (1.8 MB)
  • 64 Views
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Article
A year in the life of German patients with COPD: the DACCORD observational study
Roland Buhl, Carl-Peter Criée, Peter Kardos, Claus Vogelmeier, Nadine Lossi, Claudia Mailänder & Heinrich Worth
Pages: 1639-1646
Published online: 20 Jul 2016
AbstractforA year in the life of German patients with COPD: the DACCORD observational study | Full Text | References | PDF (828.1 KB)
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Article
An antagonist of the platelet-activating factor receptor inhibits adherence of both nontypeable Haemophilus influenzae and Streptococcus pneumoniae to cultured human bronchial epithelial cells exposed to cigarette smoke
Shakti D Shukla, Rory L Fairbairn, David A Gell, Roger D Latham, Sukhwinder S Sohal, Eugene H Walters & Ronan F O’Toole
Pages: 1647-1655
Published online: 25 Jul 2016
AbstractforAn antagonist of the platelet-activating factor receptor inhibits adherence of both nontypeable Haemophilus influenzae and Streptococcus pneumoniae to cultured human bronchial epithelial cells exposed to cigarette smoke | Full Text | References | PDF (2.1 MB)
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Article
Sex differences of COPD phenotypes in nonsmoking patients
Yoonki Hong, Wonjun Ji, Soojeong An, Seon-Sook Han, Seung-Joon Lee & Woo Jin Kim
Pages: 1657-1662
Published online: 22 Jul 2016
AbstractforSex differences of COPD phenotypes in nonsmoking patients | Full Text | References | PDF (445.1 KB)
  • 81 Views
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Article
Cause-specific mortality in individuals with severe alpha 1-antitrypsin deficiency in comparison with the general population in Sweden
Hanan A Tanash, Magnus Ekström, Philippe Wagner & Eeva Piitulainen
Pages: 1663-1669
Published online: 26 Jul 2016
AbstractforCause-specific mortality in individuals with severe alpha 1-antitrypsin deficiency in comparison with the general population in Sweden | Full Text | References | PDF (252.6 KB)
  • 71 Views
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Article
Respiratory muscle strength effect on linear and nonlinear heart rate variability parameters in COPD patients
Cássia Da Luz Goulart, Julio Cristiano Simon, Paloma De Borba Schneiders, Elisabete Antunes San Martin, Ramona Cabiddu, Audrey Borghi-Silva, Renata Trimer & Andréa Lúcia Gonçalves da Silva
Pages: 1671-1677
Published online: 26 Jul 2016
AbstractforRespiratory muscle strength effect on linear and nonlinear heart rate variability parameters in COPD patients | Full Text | References | PDF (487.2 KB)
  • 201 Views
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Article
Quality of life and adherence to inhaled corticosteroids and tiotropium in COPD are related
Kirsten Koehorst-ter Huurne, Sharina Kort, Job van der Palen, Wendy JC van Beurden, Kris LL Movig, Paul van der Valk & Marjolein Brusse-Keizer
Pages: 1679-1688
Published online: 26 Jul 2016
AbstractforQuality of life and adherence to inhaled corticosteroids and tiotropium in COPD are related | Full Text | References | PDF (361 KB)
  • 68 Views
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Article
Impact of lung function on exacerbations, health care utilization, and costs among patients with COPD
Xuehua Ke, Jessica Marvel, Tzy-Chyi Yu, Debra Wertz, Caroline Geremakis, Liya Wang, Judith J Stephenson & David M Mannino
Pages: 1689-1703
Published online: 27 Jul 2016
AbstractforImpact of lung function on exacerbations, health care utilization, and costs among patients with COPD | Full Text | References | PDF (920.6 KB)
  • 85 Views
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Article
Critical role of tumor necrosis factor receptor 1 in the pathogenesis of pulmonary emphysema in mice
Masaki Fujita, Hiroshi Ouchi, Satoshi Ikegame, Eiji Harada, Takemasa Matsumoto, Junji Uchino, Yoichi Nakanishi & Kentaro Watanabe
Pages: 1705-1712
Published online: 28 Jul 2016
AbstractforCritical role of tumor necrosis factor receptor 1 in the pathogenesis of pulmonary emphysema in mice | Full Text | References | PDF (1.8 MB)
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Article
Alteration of spontaneous brain activity in COPD patients
Jiaxing Zhang, Ji Chen, Qian Yu, Cunxiu Fan, Ran Zhang, Jianzhong Lin, Tianhe Yang & Ming Fan
Pages: 1713-1719
Published online: 28 Jul 2016
AbstractforAlteration of spontaneous brain activity in COPD patients | Full Text | References | PDF (1.4 MB)
  • 103 Views
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Article
The inhibitory mechanism of Cordyceps sinensis on cigarette smoke extract-induced senescence in human bronchial epithelial cells
Ailing Liu, Jinxiang Wu, Aijun Li, Wenxiang Bi, Tian Liu, Liuzhao Cao, Yahui Liu & Liang Dong
Pages: 1721-1731
Published online: 28 Jul 2016
AbstractforThe inhibitory mechanism of Cordyceps sinensis on cigarette smoke extract-induced senescence in human bronchial epithelial cells | Full Text | References | PDF (3.9 MB)
  • 147 Views
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Article
Nrf2 expression is increased in peripheral blood mononuclear cells derived from mild–moderate ex-smoker COPD patients with persistent oxidative stress
Anna Maria Fratta Pasini, Marcello Ferrari, Chiara Stranieri, Paola Vallerio, Chiara Mozzini, Ulisse Garbin, Giorgia Zambon & Luciano Cominacini
Pages: 1733-1743
Published online: 28 Jul 2016
AbstractforNrf2 expression is increased in peripheral blood mononuclear cells derived from mild–moderate ex-smoker COPD patients with persistent oxidative stress | Full Text | References | PDF (1.1 MB)
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Article
Individualized lung function trends in alpha-1-antitrypsin deficiency: a need for patience in order to provide patient centered management?
Robert A Stockley, Ross G Edgar, Anilkumar Pillai & Alice M Turner
Pages: 1745-1756
Published online: 01 Aug 2016
AbstractforIndividualized lung function trends in alpha-1-antitrypsin deficiency: a need for patience in order to provide patient centered management? | Full Text | References | PDF (1.3 MB)
  • 85 Views
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Article
Determinants of activation for self-management in patients with COPD
YJG Korpershoek, ID Bos-Touwen, JM de Man-van Ginkel, J-WJ Lammers, MJ Schuurmans & JCA Trappenburg
Pages: 1757-1766
Published online: 01 Aug 2016
AbstractforDeterminants of activation for self-management in patients with COPD | Full Text | References | PDF (538.9 KB)
  • 307 Views
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Article
Predictors of pneumothorax following endoscopic valve therapy in patients with severe emphysema
Daniela Gompelmann, Hyun-ju Lim, Ralf Eberhardt, Vasiliki Gerovasili, Felix JF Herth, Claus Peter Heussel & Monika Eichinger
Pages: 1767-1773
Published online: 27 Oct 2022
AbstractforPredictors of pneumothorax following endoscopic valve therapy in patients with severe emphysema | Full Text | References | PDF (760.2 KB)
  • 69 Views
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Article
Impact of anemia on short-term survival in severe COPD exacerbations: a cohort study
Begum Ergan & Recai Ergün
Pages: 1775-1783
Published online: 01 Aug 2016
AbstractforImpact of anemia on short-term survival in severe COPD exacerbations: a cohort study | Full Text | References | PDF (670.5 KB)
  • 102 Views
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Article
A simple and rapid test of physical performance in chronic obstructive pulmonary disease
Ali Mufraih Albarrati, Nichola S Gale, Stephanie Enright, Margaret M Munnery, John R Cockcroft & Dennis J Shale
Pages: 1785-1791
Published online: 02 Aug 2016
AbstractforA simple and rapid test of physical performance in chronic obstructive pulmonary disease | Full Text | References | PDF (527.6 KB)
  • 80 Views
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Article
Low cost biological lung volume reduction therapy for advanced emphysema
Mostafa Bakeer, Taha Taha Abdelgawad, Raed El-Metwaly, Ahmed El-Morsi, Mohammad Khairy El-Badrawy & Solafa El-Sharawy
Pages: 1793-1800
Published online: 03 Aug 2016
AbstractforLow cost biological lung volume reduction therapy for advanced emphysema | Full Text | References | PDF (1.5 MB)
  • 54 Views
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Article
Distinct symptom experiences in subgroups of patients with COPD
Vivi L Christensen, Tone Rustøen, Bruce A Cooper, Christine Miaskowski, Anne H Henriksen, Signe B Bentsen & Are M Holm
Pages: 1801-1809
Published online: 02 Aug 2016
AbstractforDistinct symptom experiences in subgroups of patients with COPD | Full Text | References | PDF (428 KB)
  • 104 Views
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Article
Assessing the effect of culturally specific audiovisual educational interventions on attaining self-management skills for chronic obstructive pulmonary disease in Mandarin- and Cantonese-speaking patients: a randomized controlled trial
Iraj Poureslami, Susan Kwan, Stephen Lam, Nadia A Khan & John Mark FitzGerald
Pages: 1811-1822
Published online: 03 Aug 2016
AbstractforAssessing the effect of culturally specific audiovisual educational interventions on attaining self-management skills for chronic obstructive pulmonary disease in Mandarin- and Cantonese-speaking patients: a randomized controlled trial | Full Text | References | PDF (451.2 KB)
  • 198 Views
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Article
Speckle tracking echocardiography in chronic obstructive pulmonary disease and overlapping obstructive sleep apnea
Carmen Pizarro, Fabian van Essen, Fabian Linnhoff, Robert Schueler, Christoph Hammerstingl, Georg Nickenig, Dirk Skowasch & Marcel Weber
Pages: 1823-1834
Published online: 03 Aug 2016
AbstractforSpeckle tracking echocardiography in chronic obstructive pulmonary disease and overlapping obstructive sleep apnea | Full Text | References | PDF (3.1 MB)
  • 75 Views
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Article
A size-based emphysema severity index: robust to the breath-hold-level variations and correlated with clinical parameters
Jeongeun Hwang, Minho Lee, Sang Min Lee, Sang Young Oh, Yeon-Mok Oh, Namkug Kim & Joon Beom Seo
Pages: 1835-1841
Published online: 03 Aug 2016
AbstractforA size-based emphysema severity index: robust to the breath-hold-level variations and correlated with clinical parameters | Full Text | References | PDF (1.7 MB)
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Letter

Letter
The Barthel index-dyspnea: a new two-dimensional dyspnea scale
Ming-Lung Chuang
Pages: 1843-1844
Published online: 27 Oct 2022
CitationforThe Barthel index-dyspnea: a new two-dimensional dyspnea scale | Full Text | References | PDF (204.9 KB)
  • 117 Views
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Original Research

Article
Assessment of satisfaction with different dry powder inhalation devices in Greek patients with COPD and asthma: the ANASA study
Eleftherios Zervas, Konstantinos Samitas & Mina Gaga
Pages: 1845-1855
Published online: 05 Aug 2016
AbstractforAssessment of satisfaction with different dry powder inhalation devices in Greek patients with COPD and asthma: the ANASA study | Full Text | References | PDF (855 KB)
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Article
Comorbidity as a contributor to frequent severe acute exacerbation in COPD patients
Suk Hyeon Jeong, Hyun Lee, KC Carriere, Sun Hye Shin, Seong Mi Moon, Byeong-Ho Jeong, Won-Jung Koh & Hye Yun Park
Pages: 1857-1865
Published online: 04 Aug 2016
AbstractforComorbidity as a contributor to frequent severe acute exacerbation in COPD patients | Full Text | References | PDF (313.3 KB)
  • 107 Views
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Article
Community-acquired pneumonia and survival of critically ill acute exacerbation of COPD patients in respiratory intensive care units
Zhiwei Lu, Yusheng Cheng, Xiongwen Tu, Liang Chen, Hu Chen, Jian Yang, Jinyan Wang & Liqin Zhang
Pages: 1867-1872
Published online: 09 Aug 2016
AbstractforCommunity-acquired pneumonia and survival of critically ill acute exacerbation of COPD patients in respiratory intensive care units | Full Text | References | PDF (373.7 KB)
  • 110 Views
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Article
Correct usage, ease of use, and preference of two dry powder inhalers in patients with COPD: analysis of five phase III, randomized trials
John H Riley, Maggie Tabberer, Nathalie Richard, Alison Donald, Alison Church & Stephanie S Harris
Pages: 1873-1880
Published online: 12 Aug 2016
AbstractforCorrect usage, ease of use, and preference of two dry powder inhalers in patients with COPD: analysis of five phase III, randomized trials | Full Text | References | PDF (384.5 KB)
  • 70 Views
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Article
What is the impact of different spirometric criteria on the prevalence of spirometrically defined COPD and its comorbidities? Results from the population-based KORA study
Stefan Karrasch, Irene Brüske, Maia P Smith, Barbara Thorand, Cornelia Huth, Karl-Heinz Ladwig, Florian Kronenberg, Joachim Heinrich, Rolf Holle, Annette Peters & Holger Schulz
Pages: 1881-1894
Published online: 16 Aug 2016
AbstractforWhat is the impact of different spirometric criteria on the prevalence of spirometrically defined COPD and its comorbidities? Results from the population-based KORA study | Full Text | References | PDF (1.2 MB)
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Article
Obesity might be a good prognosis factor for COPD patients using domiciliary noninvasive mechanical ventilation
Hilal Altinoz, Nalan Adiguzel, Cuneyt Salturk, Gokay Gungor, Ozlem Mocin, Huriye Berk Takir, Feyza Kargin, Merih Balci, Oner Dikensoy & Zuhal Karakurt
Pages: 1895-1901
Published online: 27 Oct 2022
AbstractforObesity might be a good prognosis factor for COPD patients using domiciliary noninvasive mechanical ventilation | Full Text | References | PDF (508 KB)
  • 57 Views
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Article
Comparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study
Go Tsukuya, Takuya Samukawa, Koichiro Matsumoto, Satoru Fukuyama, Tomohiro Kumamoto, Akifumi Uchida, Chihaya Koriyama, Toshiharu Ninomiya & Hiromasa Inoue
Pages: 1903-1909
Published online: 16 Aug 2016
AbstractforComparison of the COPD Population Screener and International Primary Care Airway Group questionnaires in a general Japanese population: the Hisayama study | Full Text | References | PDF (390 KB)
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Article
Current asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study
Shyamali C Dharmage, Jennifer L Perret, John A Burgess, Caroline J Lodge, David P Johns, Paul S Thomas, Graham G Giles, John L Hopper, Michael J Abramson, E Haydn Walters & Melanie C Matheson
Pages: 1911-1920
Published online: 16 Aug 2016
AbstractforCurrent asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study | Full Text | References | PDF (344 KB)
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Methodology

Article
Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE2SPOND rationale and study design
Stephen I Rennard, Fernando J Martinez, Klaus F Rabe, Sanjay Sethi, Emilio Pizzichini, Andrew McIvor, Shahid Siddiqui, Antonio Anzueto & Haiyuan Zhu
Pages: 1921-1928
Published online: 17 Aug 2016
AbstractforEffects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE2SPOND rationale and study design | Full Text | References | PDF (424 KB)
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Original Research

Article
General practitioners’ perceptions of COPD treatment: thematic analysis of qualitative interviews
Katrine Rutkær Molin, Ingrid Egerod, Laura Staun Valentiner, Peter Lange & Henning Langberg
Pages: 1929-1937
Published online: 17 Aug 2016
AbstractforGeneral practitioners’ perceptions of COPD treatment: thematic analysis of qualitative interviews | Full Text | References | PDF (494.5 KB)
  • 536 Views
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Article
Efficacy of a self-management plan in exacerbations for patients with advanced COPD
Juan Miguel Sánchez-Nieto, Rubén Andújar-Espinosa, Roberto Bernabeu-Mora, Chunshao Hu, Beatriz Gálvez-Martínez, Andrés Carrillo-Alcaraz, Carlos Federico Álvarez-Miranda, Olga Meca-Birlanga & Eva Abad-Corpa
Pages: 1939-1947
Published online: 17 Aug 2016
AbstractforEfficacy of a self-management plan in exacerbations for patients with advanced COPD | Full Text | References | PDF (506.2 KB)
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Hypothesis

Article
Manual evaluation of the diaphragm muscle
Bruno Bordoni, F Marelli, B Morabito & B Sacconi
Pages: 1949-1956
Published online: 18 Aug 2016
AbstractforManual evaluation of the diaphragm muscle | Full Text | References | PDF (1.6 MB)
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Original Research

Article
Cut-off value of FEV1/FEV6 as a surrogate for FEV1/FVC for detecting airway obstruction in a Korean population
Kyung Soo Chung, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang & Joo Han Song
Pages: 1957-1963
Published online: 19 Aug 2016
AbstractforCut-off value of FEV1/FEV6 as a surrogate for FEV1/FVC for detecting airway obstruction in a Korean population | Full Text | References | PDF (768.1 KB)
  • 81 Views
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Article
Small pulmonary vascular alteration and acute exacerbations of COPD: quantitative computed tomography analysis
Zhiyue Wang, Xuesong Chen, Kouying Liu, Weiping Xie, Hong Wang, Yongyue Wei, Lijun Tang & Yinsu Zhu
Pages: 1965-1971
Published online: 27 Oct 2022
AbstractforSmall pulmonary vascular alteration and acute exacerbations of COPD: quantitative computed tomography analysis | Full Text | References | PDF (564 KB)
  • 57 Views
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Article
Daily home-based spirometry during withdrawal of inhaled corticosteroid in severe to very severe chronic obstructive pulmonary disease
Roberto Rodriguez-Roisin, Kay Tetzlaff, Henrik Watz, Emiel FM Wouters, Bernd Disse, Helen Finnigan, Helgo Magnussen & Peter MA Calverley
Pages: 1973-1981
Published online: 27 Oct 2022
AbstractforDaily home-based spirometry during withdrawal of inhaled corticosteroid in severe to very severe chronic obstructive pulmonary disease | Full Text | References | PDF (961.1 KB)
  • 63 Views
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Article
Automated oxygen titration and weaning with FreeO2 in patients with acute exacerbation of COPD: a pilot randomized trial
François Lellouche, Pierre-Alexandre Bouchard, Maude Roberge, Serge Simard, Erwan L’Her, François Maltais & Yves Lacasse
Pages: 1983-1990
Published online: 24 Aug 2016
AbstractforAutomated oxygen titration and weaning with FreeO2 in patients with acute exacerbation of COPD: a pilot randomized trial | Full Text | References | PDF (1.3 MB)
  • 179 Views
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Article
A randomized controlled trial of telephone-mentoring with home-based walking preceding rehabilitation in COPD
Helen Laura Cameron-Tucker, Richard Wood-Baker, Lyn Joseph, Julia A Walters, Natalie Schüz & E Haydn Walters
Pages: 1991-2000
Published online: 27 Oct 2022
AbstractforA randomized controlled trial of telephone-mentoring with home-based walking preceding rehabilitation in COPD | Full Text | References | PDF (427.8 KB)
  • 97 Views
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Article
Illness perceptions and coping determine quality of life in COPD patients
Jitske Tiemensma, Erin Gaab, Maarten Voorhaar, Guus Asijee & Adrian A Kaptein
Pages: 2001-2007
Published online: 25 Aug 2016
AbstractforIllness perceptions and coping determine quality of life in COPD patients | Full Text | References | PDF (257.5 KB)
  • 509 Views
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Article
The objective evaluation of obstructive pulmonary diseases with spirometry
Sevket Ozkaya, Adem Dirican & Tibel Tuna
Pages: 2009-2015
Published online: 25 Aug 2016
AbstractforThe objective evaluation of obstructive pulmonary diseases with spirometry | Full Text | References | PDF (2.4 MB)
  • 96 Views
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Article
The efficacy and safety of combined tiotropium and olodaterol via the Respimat® inhaler in patients with COPD: results from the Japanese sub-population of the Tonado® studies
Masakazu Ichinose, Hiroyuki Taniguchi, Ayako Takizawa, Lars Grönke, Lazaro Loaiza, Florian Voß, Yihua Zhao & Yoshinosuke Fukuchi
Pages: 2017-2027
Published online: 29 Aug 2016
AbstractforThe efficacy and safety of combined tiotropium and olodaterol via the Respimat® inhaler in patients with COPD: results from the Japanese sub-population of the Tonado® studies | Full Text | References | PDF (1.2 MB)
  • 60 Views
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Article
Highly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD
Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Atsushi Imaizumi, Hideaki Kakeya, Hajime Yamakage, Noriko Satoh-Asahara, Maki Komiyama, Hiromichi Wada, Koji Hasegawa & Tatsuya Morimoto
Pages: 2029-2034
Published online: 26 Aug 2016
AbstractforHighly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD | Full Text | References | PDF (247.8 KB)
  • 116 Views
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Article
Bronchodilator reversibility in patients with COPD revisited: short-term reproducibility
Steven Pascoe, Wei Wu, Chang-Qing Zhu & Dave Singh
Pages: 2035-2040
Published online: 29 Aug 2016
AbstractforBronchodilator reversibility in patients with COPD revisited: short-term reproducibility | Full Text | References | PDF (659.6 KB)
  • 67 Views
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Article
The efficacy of aclidinium/formoterol on lung function and symptoms in patients with COPD categorized by symptom status: a pooled analysis
Marc Miravitlles, Kenneth R Chapman, Ferran Chuecos, Anna Ribera & Esther Garcia Gil
Pages: 2041-2053
Published online: 29 Aug 2016
AbstractforThe efficacy of aclidinium/formoterol on lung function and symptoms in patients with COPD categorized by symptom status: a pooled analysis | Full Text | References | PDF (915.3 KB)
  • 54 Views
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Article
Association between Helicobacter pylori seropositivity and mild to moderate COPD: clinical implications in an Asian country with a high prevalence of H. pylori
Ha Youn Lee, Ji Won Kim, Jung Kyu Lee, Eun Young Heo, Hee Soon Chung & Deog Keom Kim
Pages: 2055-2062
Published online: 31 Aug 2016
AbstractforAssociation between Helicobacter pylori seropositivity and mild to moderate COPD: clinical implications in an Asian country with a high prevalence of H. pylori | Full Text | References | PDF (718.2 KB)
  • 63 Views
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Article
Do self-management interventions in COPD patients work and which patients benefit most? An individual patient data meta-analysis
Nini H Jonkman, Heleen Westland, Jaap CA Trappenburg, Rolf HH Groenwold, Erik WMA Bischoff, Jean Bourbeau, Christine E Bucknall, David Coultas, Tanja W Effing, Michael J Epton, Frode Gallefoss, Judith Garcia-Aymerich, Suzanne M Lloyd, Evelyn M Monninkhof, Huong Q Nguyen, Job van der Palen, Kathryn L Rice, Maria Sedeno, Stephanie JC Taylor, Thierry Troosters, Nicholas A Zwar, Arno W Hoes & Marieke J Schuurmans
Pages: 2063-2074
Published online: 31 Aug 2016
AbstractforDo self-management interventions in COPD patients work and which patients benefit most? An individual patient data meta-analysis | Full Text | References | PDF (532.8 KB)
  • 258 Views
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Article
Mid-arm and calf circumferences are stronger mortality predictors than body mass index for patients with chronic obstructive pulmonary disease
Shu-Chuan Ho, Jiun-Yi Wang, Han-Pin Kuo, Chien-Da Huang, Kang-Yun Lee, Hsiao-Chi Chuang, Po-Hao Feng, Tzu-Tao Chen & Min-Fang Hsu
Pages: 2075-2080
Published online: 31 Aug 2016
AbstractforMid-arm and calf circumferences are stronger mortality predictors than body mass index for patients with chronic obstructive pulmonary disease | Full Text | References | PDF (369.7 KB)
  • 84 Views
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Article
Invasive coronary angiography in patients with acute exacerbated COPD and elevated plasma troponin
Carmen Pizarro, Neele Herweg-Steffens, Martin Buchenroth, Wolfgang Schulte, Christian Schaefer, Christoph Hammerstingl, Nikos Werner, Georg Nickenig & Dirk Skowasch
Pages: 2081-2089
Published online: 16 Sep 2016
AbstractforInvasive coronary angiography in patients with acute exacerbated COPD and elevated plasma troponin | Full Text | References | PDF (603.8 KB)
  • 64 Views
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Article
Impact of current cough on health-related quality of life in patients with COPD
Gaëtan Deslee, Pierre-Régis Burgel, Roger Escamilla, Pascal Chanez, Isabelle Court-Fortune, Pascale Nesme-Meyer, Graziella Brinchault-Rabin, Thierry Perez, Gilles Jebrak, Denis Caillaud, Jean-Louis Paillasseur, Nicolas Roche & On behalf of the Initiatives BPCO Scientific
Pages: 2091-2097
Published online: 13 Sep 2016
AbstractforImpact of current cough on health-related quality of life in patients with COPD | Full Text | References | PDF (381 KB)
  • 197 Views
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Article
Incidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients
Marta Erdal, Ane Johannessen, Tomas Mikal Eagan, Per Bakke, Amund Gulsvik & Rune Grønseth
Pages: 2099-2108
Published online: 27 Oct 2022
AbstractforIncidence of utilization- and symptom-defined COPD exacerbations in hospital- and population-recruited patients | Full Text | References | PDF (555.7 KB)
  • 47 Views
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Article
Impact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways
Bettina Levänen, Pernilla Glader, Barbro Dahlén, Bo Billing, Ingemar Qvarfordt, Lena Palmberg, Kjell Larsson & Anders Lindén
Pages: 2109-2116
Published online: 06 Sep 2016
AbstractforImpact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways | Full Text | References | PDF (1.5 MB)
  • 56 Views
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Article
Inflammatory biomarkers in asthma-COPD overlap syndrome
Seiichi Kobayashi, Masakazu Hanagama, Shinsuke Yamanda, Masatsugu Ishida & Masaru Yanai
Pages: 2117-2123
Published online: 07 Sep 2016
AbstractforInflammatory biomarkers in asthma-COPD overlap syndrome | Full Text | References | PDF (423.7 KB)
  • 108 Views
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Article
Application of the homology method for quantification of low-attenuation lung region inpatients with and without COPD
Mizuho Nishio, Kazuaki Nakane & Yutaka Tanaka
Pages: 2125-2137
Published online: 06 Sep 2016
AbstractforApplication of the homology method for quantification of low-attenuation lung region inpatients with and without COPD | Full Text | References | PDF (5.2 MB)
  • 59 Views
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Article
Neutral sphingomyelinase-2, acid sphingomyelinase, and ceramide levels in COPD patients compared to controls
Simon R Lea, Hannah J Metcalfe, Jonathan Plumb, Christian Beerli, Chris Poll, Dave Singh & Katharine H Abbott-Banner
Pages: 2139-2147
Published online: 06 Sep 2016
AbstractforNeutral sphingomyelinase-2, acid sphingomyelinase, and ceramide levels in COPD patients compared to controls | Full Text | References | PDF (2.1 MB)
  • 64 Views
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Article
Fractional exhaled nitric oxide levels in asthma–COPD overlap syndrome: analysis of the National Health and Nutrition Examination Survey, 2007–2012
Tadahiro Goto, Carlos A Camargo Jr & Kohei Hasegawa
Pages: 2149-2155
Published online: 07 Sep 2016
AbstractforFractional exhaled nitric oxide levels in asthma–COPD overlap syndrome: analysis of the National Health and Nutrition Examination Survey, 2007–2012 | Full Text | References | PDF (527.2 KB)
  • 51 Views
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Letter

Letter
Static lung volume should be used to confirm restrictive lung disease
Shweta A Rasam & Nitin V Vanjare
Pages: 2157-2158
Published online: 08 Sep 2016
CitationforStatic lung volume should be used to confirm restrictive lung disease | Full Text | References | PDF (216.5 KB)
  • 43 Views
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Original Research

Article
The association of renin–angiotensin system blockades and pneumonia requiring admission in patients with COPD
Junghyun Kim, Jung-Kyu Lee, Eun Young Heo, Hee Soon Chung & Deog Kyeom Kim
Pages: 2159-2166
Published online: 09 Sep 2016
AbstractforThe association of renin–angiotensin system blockades and pneumonia requiring admission in patients with COPD | Full Text | References | PDF (339.3 KB)
  • 65 Views
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Letter

Letter
Lost in interpretation: should the highest VC value be used to calculate the FEV1/VC ratio?
Spyridon Fortis
Pages: 2167-2170
Published online: 09 Sep 2016
First Page PreviewforLost in interpretation: should the highest VC value be used to calculate the FEV1/VC ratio? | Full Text | References | PDF (263.3 KB)
  • 63 Views
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Original Research

Article
Scabies increased the risk and severity of COPD: a nationwide population-based study
Jung-Yueh Chen, Jui-Ming Liu, Fung-Wei Chang, Hung Chang, Kuan-Chen Cheng, Chia-Lun Yeh, Yu-Feng Wei & Ren-Jun Hsu
Pages: 2171-2178
Published online: 27 Oct 2022
AbstractforScabies increased the risk and severity of COPD: a nationwide population-based study | Full Text | References | PDF (384.1 KB)
  • 104 Views
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Article
The disease burden of chronic obstructive pulmonary disease in Greece
Georgia Kourlaba, Georgios Hillas, Theodoros Vassilakopoulos & Nikos Maniadakis
Pages: 2179-2189
Published online: 09 Sep 2016
AbstractforThe disease burden of chronic obstructive pulmonary disease in Greece | Full Text | References | PDF (529.7 KB)
  • 72 Views
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Article
Cost-effectiveness and budget impact of the fixed-dose dual bronchodilator combination tiotropium–olodaterol for patients with COPD in the Netherlands
Job FM van Boven, Janwillem WH Kocks & Maarten J Postma
Pages: 2191-2201
Published online: 19 Sep 2016
AbstractforCost-effectiveness and budget impact of the fixed-dose dual bronchodilator combination tiotropium–olodaterol for patients with COPD in the Netherlands | Full Text | References | PDF (836 KB)
  • 73 Views
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Article
Differences in physical activity according to mMRC grade in patients with COPD
Atsushi Hayata, Yoshiaki Minakata, Kazuto Matsunaga, Masanori Nakanishi & Nobuyuki Yamamoto
Pages: 2203-2208
Published online: 13 Sep 2016
AbstractforDifferences in physical activity according to mMRC grade in patients with COPD | Full Text | References | PDF (758.1 KB)
  • 149 Views
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Letter

Letter
Noninvasive mechanical ventilation on the ward for severe COPD: still unresolved question of balance among safety and drawbacks?
Angelo Petroianni & Antonio M Esquinas
Pages: 2209-2210
Published online: 27 Oct 2022
CitationforNoninvasive mechanical ventilation on the ward for severe COPD: still unresolved question of balance among safety and drawbacks? | Full Text | References | PDF (208.3 KB)
  • 39 Views
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Original Research

Article
Health-related quality of life in current smokers with COPD: factors associated with current smoking and new insights into sex differences
Vinay K Cheruvu, Lorriane A Odhiambo, Dana S Mowls, Melissa D Zullo & Abdi T Gudina
Pages: 2211-2219
Published online: 15 Sep 2016
AbstractforHealth-related quality of life in current smokers with COPD: factors associated with current smoking and new insights into sex differences | Full Text | References | PDF (318.6 KB)
  • 125 Views
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Article
Correlates of disease-specific knowledge in Chinese patients with COPD
Carlos KH Wong & WC Yu
Pages: 2221-2227
Published online: 14 Sep 2016
AbstractforCorrelates of disease-specific knowledge in Chinese patients with COPD | Full Text | References | PDF (388.2 KB)
  • 116 Views
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Article
Prevalence of comorbidities according to predominant phenotype and severity of chronic obstructive pulmonary disease
Gianna Camiciottoli, Francesca Bigazzi, Chiara Magni, Viola Bonti, Stefano Diciotti, Maurizio Bartolucci, Mario Mascalchi & Massimo Pistolesi
Pages: 2229-2236
Published online: 14 Sep 2016
AbstractforPrevalence of comorbidities according to predominant phenotype and severity of chronic obstructive pulmonary disease | Full Text | References | PDF (738.5 KB)
  • 86 Views
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Article
Systolic time intervals combined with Valsalva maneuver for the diagnosis of left ventricular dysfunction in COPD exacerbations
Hamdi Boubaker, Mohamed Habib Grissa, Kaouther Beltaief, Zohra Dridi, Mohamed Fadhel Najjar, Wahid Bouida, Riadh Boukef, Soudani Marghli & Semir Nouira
Pages: 2237-2243
Published online: 27 Oct 2022
AbstractforSystolic time intervals combined with Valsalva maneuver for the diagnosis of left ventricular dysfunction in COPD exacerbations | Full Text | References | PDF (493.3 KB)
  • 53 Views
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Article
Interleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD
Anders Andersson, Carina Malmhäll, Birgitta Houltz, Sara Tengvall, Margareta Sjöstrand, Ingemar Qvarfordt, Anders Lindén & Apostolos Bossios
Pages: 2245-2258
Published online: 15 Sep 2016
AbstractforInterleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD | Full Text | References | PDF (1.4 MB)
  • 66 Views
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Letter

Letter
The use of high-flow nasal oxygen in COPD patients
Pedro Silva Santos & Antonio M Esquinas
Pages: 2259-2260
Published online: 27 Oct 2022
CitationforThe use of high-flow nasal oxygen in COPD patients | Full Text | References | PDF (224.1 KB)
  • 61 Views
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Original Research

Article
Myocardial performance index correlates with the BODE index and affects quality of life in COPD patients
Daniela Graner Schuwartz Tannus-Silva, João Batista Masson-Silva, Lays Silva Ribeiro, Marcus Barreto Conde & Marcelo Fouad Rabahi
Pages: 2261-2268
Published online: 16 Sep 2016
AbstractforMyocardial performance index correlates with the BODE index and affects quality of life in COPD patients | Full Text | References | PDF (890.4 KB)
  • 54 Views
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Article
The effect of domiciliary noninvasive ventilation on clinical outcomes in stable and recently hospitalized patients with COPD: a systematic review and meta-analysis
Janine Dretzke, David Moore, Chirag Dave, Rahul Mukherjee, Malcolm J Price, Sue Bayliss, Xiaoying Wu, Rachel E Jordan & Alice M Turner
Pages: 2269-2286
Published online: 16 Sep 2016
AbstractforThe effect of domiciliary noninvasive ventilation on clinical outcomes in stable and recently hospitalized patients with COPD: a systematic review and meta-analysis | Full Text | References | PDF (1.7 MB)
  • 126 Views
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Article
Breakdown of lung framework and an increase in pores of Kohn as initial events of emphysema and a cause of reduction in diffusing capacity
Akira Yoshikawa, Shuntaro Sato, Tomonori Tanaka, Mikiko Hashisako, Yukio Kashima, Tomoshi Tsuchiya, Naoya Yamasaki, Takeshi Nagayasu, Hiroshi Yamamoto & Junya Fukuoka
Pages: 2287-2294
Published online: 16 Sep 2016
AbstractforBreakdown of lung framework and an increase in pores of Kohn as initial events of emphysema and a cause of reduction in diffusing capacity | Full Text | References | PDF (3.5 MB)
  • 87 Views
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Review

Review Article
What else should we know about experiencing COPD? A narrative review in search of patients’ psychological burden alleviation
Marta Rzadkiewicz, Ola Bråtas & Geir Arild Espnes
Pages: 2295-2304
Published online: 16 Sep 2016
AbstractforWhat else should we know about experiencing COPD? A narrative review in search of patients’ psychological burden alleviation | Full Text | References | PDF (350.6 KB)
  • 161 Views
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Original Research

Article
Influence of country-level differences on COPD prevalence
Shawn D Aaron, Andrea S Gershon, Yuan Gao, Jenna Yang, GA Whitmore & On behalf of the Canadian Respiratory Research Network
Pages: 2305-2313
Published online: 27 Oct 2022
AbstractforInfluence of country-level differences on COPD prevalence | Full Text | References | PDF (600 KB)
  • 139 Views
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Article
Preference for different relaxation techniques by COPD patients: comparison between six techniques
Michael E Hyland, David MG Halpin, Sue Blake, Clare Seamark, Margaret Pinnuck, David Ward, Ben Whalley, Colin J Greaves, Adam L Hawkins & Dave Seamark
Pages: 2315-2319
Published online: 19 Sep 2016
AbstractforPreference for different relaxation techniques by COPD patients: comparison between six techniques | Full Text | References | PDF (284.8 KB)
  • 302 Views
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Article
Chronic Pseudomonas aeruginosa infection-induced chronic bronchitis and emphysematous changes in CCSP-deficient mice
Takemasa Matsumoto, Masaki Fujita, Ryosuke Hirano, Junji Uchino, Yukari Tajiri, Satoru Fukuyama, Yasuo Morimoto & Kentaro Watanabe
Pages: 2321-2327
Published online: 20 Sep 2016
AbstractforChronic Pseudomonas aeruginosa infection-induced chronic bronchitis and emphysematous changes in CCSP-deficient mice | Full Text | References | PDF (1.6 MB)
  • 56 Views
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Article
Increased mortality in patients with severe COPD associated with high-intensity exercise: a preliminary cohort study
Lone Schaadt, Robin Christensen, Lars Erik Kristensen & Marius Henriksen
Pages: 2329-2334
Published online: 26 Sep 2016
AbstractforIncreased mortality in patients with severe COPD associated with high-intensity exercise: a preliminary cohort study | Full Text | References | PDF (458.7 KB)
  • 73 Views
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Article
Mortality associated with bone fractures in COPD patients
Yasuhiro Yamauchi, Hideo Yasunaga, Yukiyo Sakamoto, Wakae Hasegawa, Hideyuki Takeshima, Hirokazu Urushiyama, Taisuke Jo, Hiroki Matsui, Kiyohide Fushimi & Takahide Nagase
Pages: 2335-2340
Published online: 27 Oct 2022
AbstractforMortality associated with bone fractures in COPD patients | Full Text | References | PDF (361.6 KB)
  • 74 Views
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Article
Effectiveness using higher inhaled corticosteroid dosage in patients with COPD by different blood eosinophilic counts
Shih-Lung Cheng & Ching-Hsiung Lin
Pages: 2341-2348
Published online: 21 Sep 2016
AbstractforEffectiveness using higher inhaled corticosteroid dosage in patients with COPD by different blood eosinophilic counts | Full Text | References | PDF (670.1 KB)
  • 67 Views
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Article
Impaired training-induced adaptation of blood pressure in COPD patients: implication of the muscle capillary bed
Fares Gouzi, Jonathan Maury, François Bughin, Marine Blaquière, Bronia Ayoub, Jacques Mercier, Antonia Perez-Martin, Pascal Pomiès & Maurice Hayot
Pages: 2349-2357
Published online: 27 Oct 2022
AbstractforImpaired training-induced adaptation of blood pressure in COPD patients: implication of the muscle capillary bed | Full Text | References | PDF (1.1 MB)
  • 62 Views
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Article
Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD
Amir Soltani, Eugene Haydn Walters, David W Reid, Shakti Dhar Shukla, Kaosia Nowrin, Chris Ward, H Konrad Muller & Sukhwinder Singh Sohal
Pages: 2359-2367
Published online: 22 Sep 2016
AbstractforInhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD | Full Text | References | PDF (1.9 MB)
  • 55 Views
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Article
Elevated circulating PAI-1 levels are related to lung function decline, systemic inflammation, and small airway obstruction in chronic obstructive pulmonary disease
Hao Wang, Ting Yang, Diandian Li, Yanqiu Wu, Xue Zhang, Caishuang Pang, Junlong Zhang, Binwu Ying, Tao Wang & Fuqiang Wen
Pages: 2369-2376
Published online: 27 Oct 2022
AbstractforElevated circulating PAI-1 levels are related to lung function decline, systemic inflammation, and small airway obstruction in chronic obstructive pulmonary disease | Full Text | References | PDF (818.5 KB)
  • 62 Views
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Commentary

Article Commentary
Can resistive breathing injure the lung? Implications for COPD exacerbations
Theodoros Vassilakopoulos & Dimitrios Toumpanakis
Pages: 2377-2384
Published online: 26 Sep 2016
AbstractforCan resistive breathing injure the lung? Implications for COPD exacerbations | Full Text | References | PDF (1.5 MB)
  • 56 Views
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Original Research

Article
Importance of fractional exhaled nitric oxide in the differentiation of asthma–COPD overlap syndrome, asthma, and COPD
Feng-jia Chen, Xin-yan Huang, Yang-li Liu, Geng-peng Lin & Can-mao Xie
Pages: 2385-2390
Published online: 26 Sep 2016
AbstractforImportance of fractional exhaled nitric oxide in the differentiation of asthma–COPD overlap syndrome, asthma, and COPD | Full Text | References | PDF (462.8 KB)
  • 135 Views
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Article
Prevalence of undiagnosed airflow obstruction among people with a history of smoking in a primary care setting
Sau Nga Fu, Wai Cho Yu, Carlos King-Ho Wong & Margaret Choi-Hing Lam
Pages: 2391-2399
Published online: 27 Sep 2016
AbstractforPrevalence of undiagnosed airflow obstruction among people with a history of smoking in a primary care setting | Full Text | References | PDF (419.3 KB)
  • 53 Views
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Article
The influence of frailty syndrome on acceptance of illness in elderly patients with chronic obstructive pulmonary disease
Izabella Uchmanowicz, Beata Jankowska-Polanska, Mariusz Chabowski, Bartosz Uchmanowicz & Andrzej M Fal
Pages: 2401-2407
Published online: 29 Sep 2016
AbstractforThe influence of frailty syndrome on acceptance of illness in elderly patients with chronic obstructive pulmonary disease | Full Text | References | PDF (311.4 KB)
  • 117 Views
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Article
Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants
Anna Pomerenke, Simon R Lea, Sarah Herrick, Mark A Lindsay & Dave Singh
Pages: 2409-2417
Published online: 29 Sep 2016
AbstractforCharacterization of TLR-induced inflammatory responses in COPD and control lung tissue explants | Full Text | References | PDF (666.8 KB)
  • 91 Views
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Open Access
Article
Evaluation of body composition in COPD patients using multifrequency bioelectrical impedance analysis
Francesca de Blasio, Francesco de Blasio, Giulia Miracco Berlingieri, Andrea Bianco, Marta La Greca, Frits M E Franssen & Luca Scalfi
Pages: 2419-2426
Published online: 30 Sep 2016
AbstractforEvaluation of body composition in COPD patients using multifrequency bioelectrical impedance analysis | Full Text | References | PDF (372.6 KB)
  • 135 Views
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Article
An in silico analysis of oxygen uptake of a mild COPD patient during rest and exercise using a portable oxygen concentrator
Ira Katz, Marine Pichelin, Spyridon Montesantos, Min-Yeong Kang, Bernard Sapoval, Kaixian Zhu, Charles-Philippe Thevenin, Robert McCoy, Andrew R Martin & Georges Caillibotte
Pages: 2427-2434
Published online: 29 Sep 2016
AbstractforAn in silico analysis of oxygen uptake of a mild COPD patient during rest and exercise using a portable oxygen concentrator | Full Text | References | PDF (914.2 KB)
  • 76 Views
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Article
Tryptophan catabolism in acute exacerbations of chronic obstructive pulmonary disease
Makedonka Gulcev, Cavan Reilly, Timothy J Griffin, Corey D Broeckling, Brian J Sandri, Bruce A Witthuhn, Shane W Hodgson, Prescott G Woodruff & Chris H Wendt
Pages: 2435-2446
Published online: 29 Sep 2016
AbstractforTryptophan catabolism in acute exacerbations of chronic obstructive pulmonary disease | Full Text | References | PDF (781.6 KB)
  • 72 Views
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Article
Image-enhanced bronchoscopic evaluation of bronchial mucosal microvasculature in COPD
Eman M Metwally, Hanaa Shafiek, Tamer S Morsi, Bassma El Sabaa, Abdelaziz Elnekidy, Mohamed Elhoffy & Mohamed Samy Atta
Pages: 2447-2455
Published online: 29 Sep 2016
AbstractforImage-enhanced bronchoscopic evaluation of bronchial mucosal microvasculature in COPD | Full Text | References | PDF (1.1 MB)
  • 56 Views
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Article
Characterization of sputum biomarkers for asthma–COPD overlap syndrome
Jing Gao, Hiroshi Iwamoto, Jukka Koskela, Harri Alenius, Noboru Hattori, Nobuoki Kohno, Tarja Laitinen, Witold Mazur & Ville Pulkkinen
Pages: 2457-2465
Published online: 30 Sep 2016
AbstractforCharacterization of sputum biomarkers for asthma–COPD overlap syndrome | Full Text | References | PDF (585.6 KB)
  • 101 Views
  • 38 CrossRef citations
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Article
Comparison of the clinical characteristics and treatment outcomes of patients requiring hospital admission to treat eosinophilic and neutrophilic exacerbations of COPD
Hye Seon Kang, Chin Kook Rhee, Sung Kyoung Kim, Jin Woo Kim, Sang Haak Lee, Hyung Kyu Yoon, Joong Hyun Ahn & Yong Hyun Kim
Pages: 2467-2473
Published online: 03 Oct 2016
AbstractforComparison of the clinical characteristics and treatment outcomes of patients requiring hospital admission to treat eosinophilic and neutrophilic exacerbations of COPD | Full Text | References | PDF (351.3 KB)
  • 73 Views
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Review

Review Article
Defining and targeting health disparities in chronic obstructive pulmonary disease
Roy A Pleasants, Isaretta L Riley & David M Mannino
Pages: 2475-2496
Published online: 04 Oct 2016
AbstractforDefining and targeting health disparities in chronic obstructive pulmonary disease | Full Text | References | PDF (760.4 KB)
  • 1006 Views
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Original Research

Article
Socioeconomic status and COPD among low- and middle-income countries
Matthew Grigsby, Trishul Siddharthan, Muhammad AH Chowdhury, Ali Siddiquee, Adolfo Rubinstein, Edgardo Sobrino, J Jaime Miranda, Antonio Bernabe-Ortiz, Dewan Alam & William Checkley
Pages: 2497-2507
Published online: 05 Oct 2016
AbstractforSocioeconomic status and COPD among low- and middle-income countries | Full Text | References | PDF (649.9 KB)
  • 671 Views
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Open Access
Article
Influence of inhaler technique on asthma and COPD control: a multicenter experience
Aleksandra Dudvarski Ilic, Vladimir Zugic, Biljana Zvezdin, Ivan Kopitovic, Ivan Cekerevac, Vojislav Cupurdija, Nela Perhoc, Vesna Veljkovic & Aleksandra Barac
Pages: 2509-2517
Published online: 06 Oct 2016
AbstractforInfluence of inhaler technique on asthma and COPD control: a multicenter experience | Full Text | References | PDF (764.3 KB)
  • 388 Views
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Article
Early COPD patients with lung hyperinflation associated with poorer lung function but better bronchodilator responsiveness
Chunlan Chen, Wenhua Jian, Yi Gao, Yanqing Xie, Yan Song & Jinping Zheng
Pages: 2519-2526
Published online: 06 Oct 2016
AbstractforEarly COPD patients with lung hyperinflation associated with poorer lung function but better bronchodilator responsiveness | Full Text | References | PDF (725 KB)
  • 64 Views
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Article
Hand grip strength is associated with forced expiratory volume in 1 second among subjects with COPD: report from a population-based cohort study
Viktor Johansson Strandkvist, Helena Backman, Jenny Röding, Caroline Stridsman & Anne Lindberg
Pages: 2527-2534
Published online: 07 Oct 2016
AbstractforHand grip strength is associated with forced expiratory volume in 1 second among subjects with COPD: report from a population-based cohort study | Full Text | References | PDF (817.3 KB)
  • 106 Views
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Article
Application of a diagnostic algorithm for the rare deficient variant Mmalton of alpha-1-antitrypsin deficiency: a new approach
Irene Belmonte, Miriam Barrecheguren, Rosa M López-Martínez, Cristina Esquinas, Esther Rodríguez, Marc Miravitlles & Francisco Rodríguez-Frías
Pages: 2535-2541
Published online: 11 Oct 2016
AbstractforApplication of a diagnostic algorithm for the rare deficient variant Mmalton of alpha-1-antitrypsin deficiency: a new approach | Full Text | References | PDF (339.5 KB)
  • 62 Views
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Article
Efficacy and safety of indacaterol/glycopyrronium in Japanese patients with COPD: a subgroup analysis from the SHINE study
Shu Hashimoto, Hisataro Ikeuchi, Shujiro Murata, Tetsuji Kitawaki, Kimitoshi Ikeda & Donald Banerji
Pages: 2543-2551
Published online: 11 Oct 2016
AbstractforEfficacy and safety of indacaterol/glycopyrronium in Japanese patients with COPD: a subgroup analysis from the SHINE study | Full Text | References | PDF (2 MB)
  • 65 Views
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Article
Chronotropic incompetence can limit exercise tolerance in COPD patients with lung hyperinflation
Sébastien Hulo, Jocelyn Inamo, Aurélie Dehon, Olivier Le Rouzic, Jean-Louis Edme & Remi Neviere
Pages: 2553-2561
Published online: 17 Oct 2016
AbstractforChronotropic incompetence can limit exercise tolerance in COPD patients with lung hyperinflation | Full Text | References | PDF (445.1 KB)
  • 52 Views
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Article
TRPM8 genetic variations associated with COPD risk in the Chinese Han population
Mingmei Xiong, Jian Wang, Meihua Guo, Qipeng Zhou & Wenju Lu
Pages: 2563-2571
Published online: 14 Oct 2016
AbstractforTRPM8 genetic variations associated with COPD risk in the Chinese Han population | Full Text | References | PDF (417.2 KB)
  • 58 Views
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Article
Reduction of neutrophilic lung inflammation by inhalation of the compatible solute ectoine: a randomized trial with elderly individuals
Klaus Unfried, Ursula Krämer, Ulrich Sydlik, Andrea Autengruber, Andreas Bilstein, Sabine Stolz, Alessandra Marini, Tamara Schikowski, Stefanie Keymel & Jean Krutmann
Pages: 2573-2583
Published online: 18 Oct 2016
AbstractforReduction of neutrophilic lung inflammation by inhalation of the compatible solute ectoine: a randomized trial with elderly individuals | Full Text | References | PDF (696.8 KB)
  • 120 Views
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Review

Review Article
A review of nebulized drug delivery in COPD
Donald P Tashkin
Pages: 2585-2596
Published online: 18 Oct 2016
AbstractforA review of nebulized drug delivery in COPD | Full Text | References | PDF (1,015.6 KB)
  • 515 Views
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Original Research

Article
The association between vitamin D and COPD risk, severity, and exacerbation: an updated systematic review and meta-analysis
Min Zhu, Ting Wang, Chengdi Wang & Yulin Ji
Pages: 2597-2607
Published online: 19 Oct 2016
AbstractforThe association between vitamin D and COPD risk, severity, and exacerbation: an updated systematic review and meta-analysis | Full Text | References | PDF (709.2 KB)
  • 257 Views
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Article
Is the 1-minute sit-to-stand test a good tool for the evaluation of the impact of pulmonary rehabilitation? Determination of the minimal important difference in COPD
Trija Vaidya, Claire de Bisschop, Marc Beaumont, Hakima Ouksel, Véronique Jean, François Dessables, Arnaud Chambellan & On behalf of IRSR RéhaEffort cohort group
Pages: 2609-2616
Published online: 27 Oct 2022
AbstractforIs the 1-minute sit-to-stand test a good tool for the evaluation of the impact of pulmonary rehabilitation? Determination of the minimal important difference in COPD | Full Text | References | PDF (622.4 KB)
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Article
New evidence of increased risk of rhinitis in subjects with COPD: a longitudinal population study
Joel Bergqvist, Anders Andersson, Anna-Carin Olin, Nicola Murgia, Linus Schiöler, Mogens Bove & Johan Hellgren
Pages: 2617-2623
Published online: 19 Oct 2016
AbstractforNew evidence of increased risk of rhinitis in subjects with COPD: a longitudinal population study | Full Text | References | PDF (575.8 KB)
  • 86 Views
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Article
Costs of chronic obstructive pulmonary disease in urban areas of China: a cross-sectional study in four cities
Xiaoying Chen, Na Wang, Yue Chen, Tian Xiao, Chaowei Fu & Biao Xu
Pages: 2625-2632
Published online: 27 Oct 2022
AbstractforCosts of chronic obstructive pulmonary disease in urban areas of China: a cross-sectional study in four cities | Full Text | References | PDF (412.3 KB)
  • 126 Views
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Article
C-reactive protein in outpatients with acute exacerbation of COPD: its relationship with microbial etiology and severity
Miguel Gallego, Xavier Pomares, Silvia Capilla, Maria Angeles Marcos, David Suárez, Eduard Monsó & Concepción Montón
Pages: 2633-2640
Published online: 21 Oct 2016
AbstractforC-reactive protein in outpatients with acute exacerbation of COPD: its relationship with microbial etiology and severity | Full Text | References | PDF (761.6 KB)
  • 135 Views
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Article
Childhood maltreatment as a risk factor for COPD: findings from a population-based survey of Canadian adults
Margot E Shields, Wendy E Hovdestad, Charles P Gilbert & Lil E Tonmyr
Pages: 2641-2650
Published online: 27 Oct 2022
AbstractforChildhood maltreatment as a risk factor for COPD: findings from a population-based survey of Canadian adults | Full Text | References | PDF (435 KB)
  • 94 Views
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Article
Prescription of opioids for breathlessness in end-stage COPD: a national population-based study
Zainab Ahmadi, Eva Bernelid, David C Currow & Magnus Ekström
Pages: 2651-2657
Published online: 21 Oct 2016
AbstractforPrescription of opioids for breathlessness in end-stage COPD: a national population-based study | Full Text | References | PDF (475.3 KB)
  • 212 Views
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Article
Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study
Ulrik Winning Iepsen, Gregers Druedal Wibe Munch, Mette Rugbjerg, Anders Rasmussen Rinnov, Morten Zacho, Stefan Peter Mortensen, Niels H Secher, Thomas Ringbaek, Bente Klarlund Pedersen, Ylva Hellsten, Peter Lange & Pia Thaning
Pages: 2659-2669
Published online: 27 Oct 2022
AbstractforEffect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study | Full Text | References | PDF (2.1 MB)
  • 165 Views
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Article
Survival after pulmonary rehabilitation in patients with COPD: impact of functional exercise capacity and its changes
Carlos A Camillo, Daniel Langer, Christian R Osadnik, Lisa Pancini, Heleen Demeyer, Chris Burtin, Rik Gosselink, Marc Decramer, Wim Janssens & Thierry Troosters
Pages: 2671-2679
Published online: 27 Oct 2022
AbstractforSurvival after pulmonary rehabilitation in patients with COPD: impact of functional exercise capacity and its changes | Full Text | References | PDF (560.8 KB)
  • 241 Views
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Article
Management of COPD, equal treatment across age, gender, and social situation? A register study
Ingela Henoch, Susann Strang, Claes-Göran Löfdahl & Ann Ekberg-Jansson
Pages: 2681-2690
Published online: 26 Oct 2016
AbstractforManagement of COPD, equal treatment across age, gender, and social situation? A register study | Full Text | References | PDF (346.8 KB)
  • 156 Views
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Article
Effects of aerobic training combined with respiratory muscle stretching on the functional exercise capacity and thoracoabdominal kinematics in patients with COPD: a randomized and controlled trial
Juliano T Wada, Erickson Borges-Santos, Desiderio Cano Porras, Denise M Paisani, Alberto Cukier, Adriana C Lunardi & Celso RF Carvalho
Pages: 2691-2700
Published online: 28 Oct 2016
AbstractforEffects of aerobic training combined with respiratory muscle stretching on the functional exercise capacity and thoracoabdominal kinematics in patients with COPD: a randomized and controlled trial | Full Text | References | PDF (728.4 KB)
  • 565 Views
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Article
Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO® and OTEMTO® studies: a subgroup analysis by age
Gary T Ferguson, Jill P Karpel, Emmanuelle Clerisme-Beaty, Lars Grönke, Florian Voß & Roland Buhl
Pages: 2701-2710
Published online: 27 Oct 2022
AbstractforEfficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO® and OTEMTO® studies: a subgroup analysis by age | Full Text | References | PDF (606.9 KB)
  • 51 Views
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Article
The effect of conjugated linoleic acid supplementation on the nutritional status of COPD patients
Hassan Ghobadi, Somaieh Matin, Ali Nemati & Abbas Naghizadeh-baghi
Pages: 2711-2720
Published online: 31 Oct 2016
AbstractforThe effect of conjugated linoleic acid supplementation on the nutritional status of COPD patients | Full Text | References | PDF (790.9 KB)
  • 62 Views
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Article
Dietary vitamin C intake protects against COPD: the Korea National Health and Nutrition Examination Survey in 2012
Hye Jung Park, Min Kwang Byun, Hyung Jung Kim, Jae Yeol Kim, Yu-Il Kim, Kwang-Ha Yoo, Eun Mi Chun, Ji Ye Jung, Sang Haak Lee, Chul Min Ahn & On behalf of the Korean Smoking Cessation Study Group
Pages: 2721-2728
Published online: 31 Oct 2016
AbstractforDietary vitamin C intake protects against COPD: the Korea National Health and Nutrition Examination Survey in 2012 | Full Text | References | PDF (409.9 KB)
  • 156 Views
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Article
Prognostic role of D-dimer for in-hospital and 1-year mortality in exacerbations of COPD
Guoping Hu, Yankui Wu, Yumin Zhou, Zelong Wu, Liping Wei, Yuqun Li, GongYong Peng, Weiqiang Liang & Pixin Ran
Pages: 2729-2736
Published online: 31 Oct 2016
AbstractforPrognostic role of D-dimer for in-hospital and 1-year mortality in exacerbations of COPD | Full Text | References | PDF (609.1 KB)
  • 76 Views
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Article
Platelet–lymphocyte ratios: a potential marker for pulmonary tuberculosis diagnosis in COPD patients
Guozhong Chen, Chunling Wu, Zhiying Luo, Yiming Teng & Suping Mao
Pages: 2737-2740
Published online: 03 Nov 2016
AbstractforPlatelet–lymphocyte ratios: a potential marker for pulmonary tuberculosis diagnosis in COPD patients | Full Text | References | PDF (247.2 KB)
  • 155 Views
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Article
Sputum microbiology predicts health status in COPD
Dionne CW Braeken, Sarah Houben-Wilke, Dionne E Smid, Gernot GU Rohde, Jesse JC Drijkoningen, Emiel FM Wouters, Martijn A Spruit & Frits ME Franssen
Pages: 2741-2748
Published online: 07 Nov 2016
AbstractforSputum microbiology predicts health status in COPD | Full Text | References | PDF (731.2 KB)
  • 94 Views
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Article
Comparative analysis of budesonide/formoterol and fluticasone/salmeterol combinations in COPD patients: findings from a real-world analysis in an Italian setting
Valentina Perrone, Diego Sangiorgi, Stefano Buda & Luca Degli Esposti
Pages: 2749-2755
Published online: 27 Oct 2022
AbstractforComparative analysis of budesonide/formoterol and fluticasone/salmeterol combinations in COPD patients: findings from a real-world analysis in an Italian setting | Full Text | References | PDF (465.8 KB)
  • 108 Views
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Article
Effects of long-term bronchodilators in bronchiectasis patients with airflow limitation based on bronchodilator response at baseline
Ho Jung Jeong, Hyun Lee, Keumhee C Carriere, Jung Hoon Kim, Jin-Hyung Han, Beomsu Shin, Byeong-Ho Jeong, Won-Jung Koh, O Jung Kwon & Hye Yun Park
Pages: 2757-2764
Published online: 07 Nov 2016
AbstractforEffects of long-term bronchodilators in bronchiectasis patients with airflow limitation based on bronchodilator response at baseline | Full Text | References | PDF (799.5 KB)
  • 100 Views
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Article
Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model
Lixing Gan, Chengye Li, Jian Wang & Xuejun Guo
Pages: 2765-2773
Published online: 07 Nov 2016
AbstractforCurcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model | Full Text | References | PDF (1.9 MB)
  • 81 Views
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Article
The association between inhaled corticosteroid and pneumonia in COPD patients: the improvement of patients’ life quality with COPD in Taiwan (IMPACT) study
Cheng-Yi Wang, Chih-Cheng Lai, Wei-Chih Yang, Chia-Chieh Lin, Likwang Chen, Hao-Chien Wang, Chong-Jen Yu & On behalf of the Taiwan Clinical Trial Consortium for Respiratory Diseases (TCORE)
Pages: 2775-2783
Published online: 08 Nov 2016
AbstractforThe association between inhaled corticosteroid and pneumonia in COPD patients: the improvement of patients’ life quality with COPD in Taiwan (IMPACT) study | Full Text | References | PDF (384.6 KB)
  • 91 Views
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Article
Pulmonary complications after abdominal surgery in patients with mild-to-moderate chronic obstructive pulmonary disease
Tae Hoon Kim, Jae Seung Lee, Sei Won Lee & Yeon-Mok Oh
Pages: 2785-2796
Published online: 09 Nov 2016
AbstractforPulmonary complications after abdominal surgery in patients with mild-to-moderate chronic obstructive pulmonary disease | Full Text | References | PDF (442.6 KB)
  • 190 Views
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Article
Combination therapy of inhaled steroids and long-acting beta2-agonists in asthma–COPD overlap syndrome
Suh-Young Lee, Hye Yun Park, Eun Kyung Kim, Seong Yong Lim, Chin Kook Rhee, Yong Il Hwang, Yeon-Mok Oh, Sang Do Lee, Yong Bum Park & On behalf of the KOLD Study Group
Pages: 2797-2803
Published online: 08 Nov 2016
AbstractforCombination therapy of inhaled steroids and long-acting beta2-agonists in asthma–COPD overlap syndrome | Full Text | References | PDF (499.1 KB)
  • 97 Views
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Article
Persistent disabling breathlessness in chronic obstructive pulmonary disease
Josefin Sundh & Magnus Ekström
Pages: 2805-2812
Published online: 09 Nov 2016
AbstractforPersistent disabling breathlessness in chronic obstructive pulmonary disease | Full Text | References | PDF (561.9 KB)
  • 173 Views
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Article
Association between hemoglobin and prognosis in patients admitted to hospital for COPD
Anne Pernille Toft-Petersen, Christian Torp-Pedersen, Ulla Møller Weinreich & Bodil Steen Rasmussen
Pages: 2813-2820
Published online: 10 Nov 2016
AbstractforAssociation between hemoglobin and prognosis in patients admitted to hospital for COPD | Full Text | References | PDF (1.1 MB)
  • 139 Views
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Article
Telemonitoring of home exercise cycle training in patients with COPD
Karl-Josef Franke, Ulrike Domanski, Maik Schroeder, Volker Jansen, Frank Artmann, Uwe Weber, Rainer Ettler & Georg Nilius
Pages: 2821-2829
Published online: 11 Nov 2016
AbstractforTelemonitoring of home exercise cycle training in patients with COPD | Full Text | References | PDF (960.4 KB)
  • 73 Views
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Article
COPD care delivery pathways in five European Union countries: mapping and health care professionals’ perceptions
Reem Kayyali, Bassel Odeh, Inéz Frerichs, Nikki Davies, Eleni Perantoni, Shona D’arcy, Anouk W Vaes, John Chang, Martijn A Spruit, Brenda Deering, Nada Philip, Roshan Siva, Evangelos Kaimakamis, Ioanna Chouvarda, Barbara Pierscionek, Norbert Weiler, Emiel FM Wouters, Andreas Raptopoulos & Shereen Nabhani-Gebara
Pages: 2831-2838
Published online: 14 Nov 2016
AbstractforCOPD care delivery pathways in five European Union countries: mapping and health care professionals’ perceptions | Full Text | References | PDF (403.9 KB)
  • 187 Views
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Article
Community-based exercise training for people with chronic respiratory and chronic cardiac disease: a mixed-methods evaluation
Renae J McNamara, Zoe J McKeough, Laura R Mo, Jamie T Dallimore & Sarah M Dennis
Pages: 2839-2850
Published online: 16 Nov 2016
AbstractforCommunity-based exercise training for people with chronic respiratory and chronic cardiac disease: a mixed-methods evaluation | Full Text | References | PDF (375.3 KB)
  • 146 Views
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Article
The burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK
Susan C Edwards, Sian E Fairbrother, Anna Scowcroft, Gavin Chiu, Andrew Ternouth & Brian J Lipworth
Pages: 2851-2858
Published online: 22 Nov 2016
AbstractforThe burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK | Full Text | References | PDF (571.6 KB)
  • 62 Views
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Article
Bronchodilator efficacy of 18 μg once-daily tiotropium inhalation via Discair® versus HandiHaler® in adults with chronic obstructive pulmonary disease: randomized, active-controlled, parallel-group, open-label, Phase IV trial
Pinar Yildiz, Mesut Bayraktaroglu, Didem Gorgun & Funda Secik
Pages: 2859-2867
Published online: 27 Oct 2022
AbstractforBronchodilator efficacy of 18 μg once-daily tiotropium inhalation via Discair® versus HandiHaler® in adults with chronic obstructive pulmonary disease: randomized, active-controlled, parallel-group, open-label, Phase IV trial | Full Text | References | PDF (470.7 KB)
  • 80 Views
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Article
Usefulness of the 6-minute walk test as a screening test for pulmonary arterial enlargement in COPD
Yutaro Oki, Masahiro Kaneko, Yukari Fujimoto, Hideki Sakai, Shogo Misu, Yuji Mitani, Takumi Yamaguchi, Hisafumi Yasuda & Akira Ishikawa
Pages: 2869-2875
Published online: 22 Nov 2016
AbstractforUsefulness of the 6-minute walk test as a screening test for pulmonary arterial enlargement in COPD | Full Text | References | PDF (970.7 KB)
  • 107 Views
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Article
Effect of ELOM-080 on exacerbations and symptoms in COPD patients with a chronic bronchitis phenotype – a post-hoc analysis of a randomized, double-blind, placebo-controlled clinical trial
Kai-Michael Beeh, Jutta Beier, Henning Candler & Thomas Wittig
Pages: 2877-2884
Published online: 23 Nov 2016
AbstractforEffect of ELOM-080 on exacerbations and symptoms in COPD patients with a chronic bronchitis phenotype – a post-hoc analysis of a randomized, double-blind, placebo-controlled clinical trial | Full Text | References | PDF (579.3 KB)
  • 54 Views
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Methodology

Article
Randomized controlled trials and real-world observational studies in evaluating cardiovascular safety of inhaled bronchodilator therapy in COPD
Peter Kardos, Sally Worsley, Dave Singh, Miguel Román-Rodríguez, David E Newby & Hana Müllerová
Pages: 2885-2895
Published online: 25 Nov 2016
AbstractforRandomized controlled trials and real-world observational studies in evaluating cardiovascular safety of inhaled bronchodilator therapy in COPD | Full Text | References | PDF (378.2 KB)
  • 78 Views
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Original Research

Article
Impact of a care pathway for COPD on adherence to guidelines and hospital readmission: a cluster randomized trial
Kris Vanhaecht, Cathy Lodewijckx, Walter Sermeus, Marc Decramer, Svin Deneckere, Fabrizio Leigheb, Paulo Boto, Seval Kul, Deborah Seys & Massimiliano Panella
Pages: 2897-2908
Published online: 27 Oct 2022
AbstractforImpact of a care pathway for COPD on adherence to guidelines and hospital readmission: a cluster randomized trial | Full Text | References | PDF (489.1 KB)
  • 145 Views
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Letter

Letter
Superiority of tiotropium plus olodaterol in comparison with salmeterol plus fluticasone
Tomohiro Tamura & Hiroaki Satoh
Pages: 2909-2911
Published online: 23 Nov 2016
First Page PreviewforSuperiority of tiotropium plus olodaterol in comparison with salmeterol plus fluticasone | Full Text | References | PDF (224.1 KB)
  • 60 Views
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Case Report

Case Report
Significant lung volume reduction with endobronchial valves in a patient despite the presence of microcollaterals masked by low-flow Chartis phenotype
Yan Yin, Gang Hou, Felix J Herth, Xiao-bo Wang, Qiu-yue Wang & Jian Kang
Pages: 2913-2917
Published online: 24 Nov 2016
AbstractforSignificant lung volume reduction with endobronchial valves in a patient despite the presence of microcollaterals masked by low-flow Chartis phenotype | Full Text | References | PDF (1.4 MB)
  • 44 Views
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Original Research

Article
Outcomes of a telemonitoring-based program (telEPOC) in frequently hospitalized COPD patients
Cristóbal Esteban, Javier Moraza, Milagros Iriberri, Urko Aguirre, Begoña Goiria, José M Quintana, Myriam Aburto & Alberto Capelastegui
Pages: 2919-2930
Published online: 27 Oct 2022
AbstractforOutcomes of a telemonitoring-based program (telEPOC) in frequently hospitalized COPD patients | Full Text | References | PDF (420.6 KB)
  • 133 Views
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Review

Review Article
Coherence between self-reported and objectively measured physical activity in patients with chronic obstructive lung disease: a systematic review
Mimi Thyregod & Uffe Bodtger
Pages: 2931-2938
Published online: 25 Nov 2016
AbstractforCoherence between self-reported and objectively measured physical activity in patients with chronic obstructive lung disease: a systematic review | Full Text | References | PDF (374.7 KB)
  • 104 Views
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Original Research

Article
Bronchodilator response of advanced lung function parameters depending on COPD severity
Linnea Jarenbäck, Göran Eriksson, Stefan Peterson, Jaro Ankerst, Leif Bjermer & Ellen Tufvesson
Pages: 2939-2950
Published online: 25 Nov 2016
AbstractforBronchodilator response of advanced lung function parameters depending on COPD severity | Full Text | References | PDF (843.3 KB)
  • 124 Views
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Article
Screening of long non-coding RNA and TUG1 inhibits proliferation with TGF-β induction in patients with COPD
Wenxiang Tang, Zhenyu Shen, Jiang Guo & Shenghua Sun
Pages: 2951-2964
Published online: 28 Nov 2016
AbstractforScreening of long non-coding RNA and TUG1 inhibits proliferation with TGF-β induction in patients with COPD | Full Text | References | PDF (2.8 MB)
  • 72 Views
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Article
Effectiveness of neuromuscular electrical stimulation for the rehabilitation of moderate-to-severe COPD: a meta-analysis
Rong-chang Chen, Xiao-ying Li, Li-li Guan, Bing-peng Guo, Wei-liang Wu, Zi-qing Zhou, Ya-ting Huo, Xin Chen & Lu-qian Zhou
Pages: 2965-2975
Published online: 28 Nov 2016
AbstractforEffectiveness of neuromuscular electrical stimulation for the rehabilitation of moderate-to-severe COPD: a meta-analysis | Full Text | References | PDF (1.4 MB)
  • 249 Views
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Article
Factors influencing exacerbation-related self-management in patients with COPD: a qualitative study
YJG Korpershoek, SCJM Vervoort, LIT Nijssen, JCA Trappenburg & MJ Schuurmans
Pages: 2977-2990
Published online: 27 Oct 2022
AbstractforFactors influencing exacerbation-related self-management in patients with COPD: a qualitative study | Full Text | References | PDF (436.7 KB)
  • 308 Views
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Article
Three-minute constant rate step test for detecting exertional dyspnea relief after bronchodilation in COPD
Benoit Borel, Courtney A Wilkinson-Maitland, Alan Hamilton, Jean Bourbeau, Hélène Perrault, Dennis Jensen & François Maltais
Pages: 2991-3000
Published online: 27 Oct 2022
AbstractforThree-minute constant rate step test for detecting exertional dyspnea relief after bronchodilation in COPD | Full Text | References | PDF (536.1 KB)
  • 99 Views
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Article
Association of serum ferritin levels with smoking and lung function in the Korean adult population: analysis of the fourth and fifth Korean National Health and Nutrition Examination Survey
Chan Ho Lee, Eun Kyung Goag, Su Hwan Lee, Kyung Soo Chung, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang & Joo Han Song
Pages: 3001-3006
Published online: 29 Nov 2016
AbstractforAssociation of serum ferritin levels with smoking and lung function in the Korean adult population: analysis of the fourth and fifth Korean National Health and Nutrition Examination Survey | Full Text | References | PDF (284.4 KB)
  • 132 Views
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Review

Review Article
Airflow obstruction: is it asthma or is it COPD?
Paola Rogliani, Josuel Ora, Ermanno Puxeddu & Mario Cazzola
Pages: 3007-3013
Published online: 30 Nov 2016
AbstractforAirflow obstruction: is it asthma or is it COPD? | Full Text | References | PDF (257 KB)
  • 269 Views
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Original Research

Article
Computer quantification of “angle of collapse” on maximum expiratory flow volume curve for diagnosing asthma-COPD overlap syndrome
Wei Wang, Mengshuang Xie, Shuang Dou, Liwei Cui & Wei Xiao
Pages: 3015-3022
Published online: 01 Dec 2016
AbstractforComputer quantification of “angle of collapse” on maximum expiratory flow volume curve for diagnosing asthma-COPD overlap syndrome | Full Text | References | PDF (543.8 KB)
  • 60 Views
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Article
Clinical factors and comorbidities affecting the cost of hospital-treated COPD
Sami Deniz, Aysun Şengül, Yusuf Aydemir, Jülide Çeldir Emre & Mustafa Hikmet Özhan
Pages: 3023-3030
Published online: 02 Dec 2016
AbstractforClinical factors and comorbidities affecting the cost of hospital-treated COPD | Full Text | References | PDF (466.1 KB)
  • 109 Views
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Article
Cigarette smoke extract induces placental growth factor release from human bronchial epithelial cells via ROS/MAPK (ERK-1/2)/Egr-1 axis
Dong Wu, Yalian Yuan, Zhixiu Lin, Tianwen Lai, Min Chen, Wen Li, Quanchao Lv, Binfan Yuan, Dongmin Li & Bin Wu
Pages: 3031-3042
Published online: 02 Dec 2016
AbstractforCigarette smoke extract induces placental growth factor release from human bronchial epithelial cells via ROS/MAPK (ERK-1/2)/Egr-1 axis | Full Text | References | PDF (2.3 MB)
  • 68 Views
  • 14 CrossRef citations
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Review

Review Article
Effects of aclidinium on determinants of COPD severity: symptoms and quality of life
Marco Contoli, Paolo Solidoro, Fabiano Di Marco, Nicola Scichilone, Angelo Corsico, Fulvio Braido & Pierachille Santus
Pages: 3043-3050
Published online: 27 Oct 2022
AbstractforEffects of aclidinium on determinants of COPD severity: symptoms and quality of life | Full Text | References | PDF (479.4 KB)
  • 54 Views
  • 4 CrossRef citations
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Original Research

Article
Increased risk of community-acquired pneumonia in COPD patients with comorbid cardiovascular disease
Sheng-Hao Lin, Diahn-Warng Perng, Ching-Pei Chen, Woei-Horng Chai, Chin-Shui Yeh, Chew-Teng Kor, Shih-Lung Cheng, Jeremy JW Chen & Ching-Hsiung Lin
Pages: 3051-3058
Published online: 27 Oct 2022
AbstractforIncreased risk of community-acquired pneumonia in COPD patients with comorbid cardiovascular disease | Full Text | References | PDF (586.1 KB)
  • 126 Views
  • 15 CrossRef citations
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Article
Exacerbations and health care resource utilization in patients with airflow limitation diseases attending a primary care setting: the PUMA study
Maria Montes de Oca, Carlos Aguirre, Maria Victorina Lopez Varela, Maria E Laucho-Contreras, Alejandro Casas & Filip Surmont
Pages: 3059-3067
Published online: 07 Dec 2016
AbstractforExacerbations and health care resource utilization in patients with airflow limitation diseases attending a primary care setting: the PUMA study | Full Text | References | PDF (560.4 KB)
  • 69 Views
  • 8 CrossRef citations
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Review

Review Article
Interpreting patient-reported outcomes from clinical trials in COPD: a discussion
Paul W Jones, Stephen Rennard, Maggie Tabberer, John H Riley, Mitra Vahdati-Bolouri & Neil C Barnes
Pages: 3069-3078
Published online: 27 Oct 2022
AbstractforInterpreting patient-reported outcomes from clinical trials in COPD: a discussion | Full Text | References | PDF (817.8 KB)
  • 95 Views
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Original Research

Article
Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis
Jinhui Li, Shengzhi Sun, Robert Tang, Hong Qiu, Qingyuan Huang, Tonya G Mason & Linwei Tian
Pages: 3079-3091
Published online: 12 Dec 2016
AbstractforMajor air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis | Full Text | References | PDF (1 MB)
  • 740 Views
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Article
Clinical and radiological outcome following pneumothorax after endoscopic lung volume reduction with valves
D Gompelmann, N Benjamin, K Kontogianni, FJF Herth, CP Heussel, H Hoffmann & R Eberhardt
Pages: 3093-3099
Published online: 07 Dec 2016
AbstractforClinical and radiological outcome following pneumothorax after endoscopic lung volume reduction with valves | Full Text | References | PDF (586.6 KB)
  • 57 Views
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Article
An evaluation of early medication use for COPD: a population-based cohort study
Jamie Falk, Natalia Dik & Shawn Bugden
Pages: 3101-3108
Published online: 07 Dec 2016
AbstractforAn evaluation of early medication use for COPD: a population-based cohort study | Full Text | References | PDF (596.1 KB)
  • 79 Views
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Article
How do general practitioners implement decision-making regarding COPD patients with exacerbations? An international focus group study
Johanna Laue, Hasse Melbye, Peder A Halvorsen, Elena A Andreeva, Maciek Godycki-Cwirko, Anja Wollny, Nick A Francis, Mark Spigt, Kenny Kung & Mette Bech Risør
Pages: 3109-3119
Published online: 08 Dec 2016
AbstractforHow do general practitioners implement decision-making regarding COPD patients with exacerbations? An international focus group study | Full Text | References | PDF (283.5 KB)
  • 138 Views
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Review

Review Article
Exercise training alone or with the addition of activity counseling improves physical activity levels in COPD: a systematic review and meta-analysis of randomized controlled trials
Aroub Lahham, Christine F McDonald & Anne E Holland
Pages: 3121-3136
Published online: 08 Dec 2016
AbstractforExercise training alone or with the addition of activity counseling improves physical activity levels in COPD: a systematic review and meta-analysis of randomized controlled trials | Full Text | References | PDF (892.1 KB)
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Original Research

Article
COPD assessment test score and serum C-reactive protein levels in stable COPD patients
Hyung Koo Kang, Kang Kim, Hyun Lee, Byeong-Ho Jeong, Won-Jung Koh & Hye Yun Park
Pages: 3137-3143
Published online: 08 Dec 2016
AbstractforCOPD assessment test score and serum C-reactive protein levels in stable COPD patients | Full Text | References | PDF (573.8 KB)
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Article
Drop in lung function during asthma and COPD exacerbations – can it be assessed without spirometry?
Hasse Melbye, Salwan Al-ani & Mark Spigt
Pages: 3145-3152
Published online: 08 Dec 2016
AbstractforDrop in lung function during asthma and COPD exacerbations – can it be assessed without spirometry? | Full Text | References | PDF (571.6 KB)
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Article
Prognostic utility of admission cell-free DNA levels in patients with chronic obstructive pulmonary disease exacerbations
Avital Avriel, Dmitry Rozenberg, Yael Raviv, Dov Heimer, Amir Bar-Shai, Rachel Gavish, Jony Sheynin & Amos Douvdevani
Pages: 3153-3161
Published online: 09 Dec 2016
AbstractforPrognostic utility of admission cell-free DNA levels in patients with chronic obstructive pulmonary disease exacerbations | Full Text | References | PDF (819.6 KB)
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Review

Review Article
Efficacy of tiotropium–olodaterol fixed-dose combination in COPD
Eric Derom, Guy G Brusselle & Guy F Joos
Pages: 3163-3177
Published online: 13 Dec 2016
AbstractforEfficacy of tiotropium–olodaterol fixed-dose combination in COPD | Full Text | References | PDF (500.5 KB)
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Review Article
Endocan and the respiratory system: a review
Maria Kechagia, Ioannis Papassotiriou & Konstantinos I Gourgoulianis
Pages: 3179-3187
Published online: 12 Dec 2016
AbstractforEndocan and the respiratory system: a review | Full Text | References | PDF (1.7 MB)
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Original Research

Article
Indacaterol/glycopyrronium in symptomatic patients with COPD (GOLD B and GOLD D) versus salmeterol/fluticasone: ILLUMINATE/LANTERN pooled analysis
Claus Vogelmeier, Nanshan Zhong, Michael J Humphries, Karen Mezzi, Robert Fogel, Giovanni Bader, Francesco Patalano & Donald Banerji
Pages: 3189-3197
Published online: 14 Dec 2016
AbstractforIndacaterol/glycopyrronium in symptomatic patients with COPD (GOLD B and GOLD D) versus salmeterol/fluticasone: ILLUMINATE/LANTERN pooled analysis | Full Text | References | PDF (1.1 MB)
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Article
Rates and predictors of depression status among caregivers of patients with COPD hospitalized for acute exacerbations: a prospective study
Roberto Bernabeu-Mora, Gloria García-Guillamón, Joaquina Montilla-Herrador, Pilar Escolar-Reina, José Antonio García-Vidal & Francesc Medina-Mirapeix
Pages: 3199-3205
Published online: 14 Dec 2016
AbstractforRates and predictors of depression status among caregivers of patients with COPD hospitalized for acute exacerbations: a prospective study | Full Text | References | PDF (341.6 KB)
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Article
The administration of a high refined carbohydrate diet promoted an increase in pulmonary inflammation and oxidative stress in mice exposed to cigarette smoke
Karina Braga Pena, Camila de Oliveira Ramos, Nícia Pedreira Soares, Pamela Félix da Silva, Ana Carla Balthar Bandeira, Guilherme de Paula Costa, Sílvia Dantas Cangussú, André Talvani & Frank Silva Bezerra
Pages: 3207-3217
Published online: 15 Dec 2016
AbstractforThe administration of a high refined carbohydrate diet promoted an increase in pulmonary inflammation and oxidative stress in mice exposed to cigarette smoke | Full Text | References | PDF (1.8 MB)
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