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International Journal of Chronic Obstructive Pulmonary Disease Volume 11, 2016 - Issue

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Original Research

α1-Antitrypsin reduces rhinovirus infection in primary human airway epithelial cells exposed to cigarette smoke

Reena BermanDepartment of Medicine, National Jewish Health, Denver, CO, USA

Di JiangDepartment of Medicine, National Jewish Health, Denver, CO, USA

Qun WuDepartment of Medicine, National Jewish Health, Denver, CO, USA

Hong Wei ChuDepartment of Medicine, National Jewish Health, Denver, CO, USACorrespondence[email protected]

Pages 1279-1286 | Published online: 10 Jun 2016

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Juan Luis Rodríguez Hermosa, Gianna Vargas Centanaro, María Estela González Castro, Marc Miravitlles, Lourdes Lázaro-Asegurado, Beatriz María Jiménez-Rodríguez, Rosanel Amaro Rodríguez, Rosaly Moreno Méndez, María Torres-Duran, José María Hernández-Pérez, Ana María Humanes-Navarro & Myriam Calle Rubio. (2023) Severe COVID-19 Illness and α1-Antitrypsin Deficiency: COVID-AATD Study. Biomedicines 11:2, pages 516.
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Niccolette Schaunaman, Kris Genelyn Dimasuay, Bruce Berg, Diana Cervantes & Hong Wei Chu. 2022. Asthma. Asthma 135 149 .

Seigo Korematsu, Toshiko Itazawa, Junichiro Teduka, Tomonobu Kikkawa, Koichi Yoshida, Kouta Hirai, Masahiko Kato, Mizuho Nagao & Takao Fujisawa. (2021) A web survey of caregivers regarding the asthma status of children during the COVID-19 pandemicコロナウイルス感染症2019流行期における気管支喘息をもつ15歳未満の小児の臨床像の実態調査. Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology 35:3, pages 248-255.
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Grace Hogan, Pierce Geoghegan, Tomás P. Carroll, Jennifer Clarke, Oisín F. McElvaney, Oliver J. McElvaney, Noel G. McElvaney & Gerard F. Curley. (2021) α1-Antitrypsin: Key Player or Bystander in Acute Respiratory Distress Syndrome?. Anesthesiology 134:5, pages 792-808.
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Sangmi S. Park, Romy Rodriguez Ortega, Christina W. Agudelo, Jessica Perez Perez, Brais Perez Gandara, Itsaso Garcia-Arcos, Cormac McCarthy & Patrick Geraghty. (2021) Therapeutic Potential of Alpha-1 Antitrypsin in Type 1 and Type 2 Diabetes Mellitus. Medicina 57:4, pages 397.
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Mariana Braccialli Loyola, Thaís Tereza Aguiar Reis, Guilherme Xavier Lyra Malcher Oliveira, Julys Fonseca Palmeira, Gustavo A. Argañaraz & Enrique R. Argañaraz. (2020) Alpha‐1‐antitrypsin : A possible host protective factor against Covid‐19 . Reviews in Medical Virology 31:2.
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Haleh Ganjian, Charu Rajput, Manal Elzoheiry & Umadevi Sajjan. (2020) Rhinovirus and Innate Immune Function of Airway Epithelium. Frontiers in Cellular and Infection Microbiology 10.
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Irene L. Indalao, Agustiningsih Agustiningsih, Eka Pratiwi, Kartika Dewi Puspa, Hartanti Dian Ikawati & Ririn Ramadhany. (2019) The Utilization of Alpha-1 Anti-trypsin (A1AT) in Infectious Disease Monitoring and Treatment. Journal of Microbiology and Infectious Diseases, pages 51-58.
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Peter Wark, Teresa Williams & Prabuddha Pathinayake. 2019. Rhinovirus Infections. Rhinovirus Infections 169 194 .

Avivit Brener, Yael Lebenthal, Hagar Interator, Orit Horesh, Avital Leshem, Naomi Weintrob, Neta Loewenthal, Shlomit Shalitin & Marianna Rachmiel. (2018) Long-term safety of α-1 antitrypsin therapy in children and adolescents with Type 1 diabetes. Immunotherapy 10:13, pages 1137-1148.
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Kris Genelyn DimasuayAmelia SanchezNiccolette SchaeferJorge PolancoDeborah A. FerringtonHong Wei Chu. (2018) Immunoproteasomes as a novel antiviral mechanism in rhinovirus-infected airways. Clinical Science 132:15, pages 1711-1723.
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Bernadett Boda, Sacha Benaoudia, Song Huang, Rosy Bonfante, Ludovic Wiszniewski, Eirini D. Tseligka, Caroline Tapparel & Samuel Constant. (2018) Antiviral drug screening by assessing epithelial functions and innate immune responses in human 3D airway epithelium model. Antiviral Research 156, pages 72-79.
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Thalita Camêlo da Silva Ferreira, Maria Alice Freitas Queiroz, Gustavo Adolfo Argañaraz, Ricardo Ishak, Antonio Carlos Rosário Vallinoto & Enrique Roberto Argañaraz. (2017) A1AT polymorphisms may be associated with clinical characteristics of retrovirus infections in a mixed ethnic population from the Brazilian Amazon region. International Journal of Infectious Diseases 65, pages 67-71.
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Reena Berman, Di Jiang, Qun Wu, Connor R. Stevenson, Niccolette R. Schaefer & Hong Wei Chu. (2016) MUC18 Regulates Lung Rhinovirus Infection and Inflammation. PLOS ONE 11:10, pages e0163927.
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α1-Antitrypsin reduces rhinovirus infection in primary human airway epithelial cells exposed to cigarette smoke

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α1-Antitrypsin reduces rhinovirus infection in primary human airway epithelial cells exposed to cigarette smoke

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