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Original Research

Blood eosinophils and inhaled corticosteroids in patients with COPD: systematic review and meta-analysis

Pages 2775-2784 | Published online: 06 Sep 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Calvin You Jia Chen, Min Sen Yew, John Arputhan Abisheganaden & Huiying Xu. (2022) Predictors of Influenza PCR Positivity in Acute Exacerbations of Chronic Obstructive Pulmonary Disease. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 25-32.
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Mathias Damkjær, Kjell Håkansson, Thomas Kallemose, Charlotte Suppli Ulrik & Nina Godtfredsen. (2021) Statins in High-Risk Chronic Obstructive Pulmonary Disease Outpatients: No Impact on Time to First Exacerbation and All-Cause Mortality – The STATUETTE Cohort Study. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 579-589.
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Ronald F. Grossman. (2021) Blood eosinophils in COPD to predict exacerbations and inform inhaled corticosteroid use: Need for further evidence?. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine 5:3, pages 136-149.
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Timothy E Albertson, Willis S Bowman, Richart W Harper, Regina M Godbout & Susan Murin. (2019) Evidence-based review of data on the combination inhaler umeclidinium/vilanterol in patients with COPD. International Journal of Chronic Obstructive Pulmonary Disease 14, pages 1251-1265.
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Articles from other publishers (25)

Anamarie Tomaich, Shawnee Klatt & Michael W. Nagy. (2021) Narrative Literature Review Guided Approach of Inhaled Corticosteroid de-escalation in Chronic Obstructive Pulmonary Disease. Journal of Pharmacy Practice 36:3, pages 628-639.
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Brooke Foster, Daniel Obidare‐Kolade & Michael Nagy. (2023) Assessment of primary care provider and pharmacist knowledge, comfort, and barriers to appropriate inhaled corticosteroid use in chronic obstructive pulmonary disease. JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY 6:4, pages 339-345.
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W. Blake LeMaster, P. Miguel Quibrera, David Couper, Donald P. Tashkin, Eugene R. Bleecker, Claire M. Doerschuk, Victor E. Ortega, Christopher Cooper, MeiLan K. Han, Prescott G. Woodruff, Wanda K. O’Neal, Wayne H. Anderson, Neil E. Alexis, Russell P. Bowler, R. Graham Barr, Robert J. Kaner, Mark T. Dransfield, Robert PaineIIIIII, Victor Kim, Jeffrey L. Curtis, Fernando J. Martinez, Annette T. Hastie & Igor Barjaktarevic. (2023) Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort. Chest 163:3, pages 515-528.
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Ricardo G. Figueiredo, Lucas F. Araujo & José de Bessa Junior. (2022) The Role of Dual Bronchodilation and the Conscientious Use of Inhaled Corticosteroid in COPD. Sinusitis 6:2, pages 32-35.
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Domenico Maurizio Toraldo, Emanuele Rizzo & Luana Conte. (2022) Effects of inhaled corticosteroids (ICS) on lung microbiota and local immune response in long-term treatment of chronic obstructive pulmonary disease (COPD): utility of titration and therapeutic index. Naunyn-Schmiedeberg's Archives of Pharmacology 395:7, pages 849-858.
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Jacklyn Nguyen, Brittnie S. Armstrong, Sophie Cowman, Yaniv Tomer, Shivakumar R. Veerabhadraiah, Michael F. Beers & Alessandro Venosa. (2022) Immunophenotyping of Acute Inflammatory Exacerbations of Lung Injury Driven by Mutant Surfactant Protein-C: A Role for Inflammatory Eosinophils. Frontiers in Pharmacology 13.
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Afshin Sam & Monica Kraft. (2022) Asthma-COPD Overlap. Current Pulmonology Reports 11:1, pages 1-14.
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Zijie Zhan, Yiming Ma, Ke Huang, Chen Liang, Xihua Mao, Yaowen Zhang, Xiaoxia Ren, Jieping Lei, Yan Chen, Ting Yang & Chen Wang. (2022) Methylxanthine Treatment in Patients Hospitalized for Acute Exacerbation of Chronic Obstructive Pulmonary Disease in China: A Real-World Study Using Propensity Score Matching Analysis. Frontiers in Pharmacology 13.
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Hsu-Hui Wang & Shih-Lung Cheng. (2021) From Biomarkers to Novel Therapeutic Approaches in Chronic Obstructive Pulmonary Disease. Biomedicines 9:11, pages 1638.
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Martine Hoogendoorn, Isaac Corro Ramos, Stéphane Soulard, Jennifer Cook, Erkki Soini, Emma Paulsson & Maureen Rutten-van Mölken. (2021) Cost-effectiveness of the fixed-dose combination tiotropium/olodaterol versus tiotropium monotherapy or a fixed-dose combination of long-acting β2-agonist/inhaled corticosteroid for COPD in Finland, Sweden and the Netherlands: a model-based study. BMJ Open 11:8, pages e049675.
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A. H. Morice, E. Millqvist, K. Bieksiene, S. S. Birring, P. Dicpinigaitis, Ch. D. RibasM. H. Boon, A. Kantar, K. Lai, L. McGarvey, D. Rigau, I. Satia, J. Smith, W.-J. Song, T. Tonia, J. W.K. Van den Berg, M. J.G. Van Manen & A. Zacharasiewicz. (2021) European Respiratory Society guidelines on the diagnosis and treatment of chronic cough in adults and children. PULMONOLOGIYA 31:4, pages 418-438.
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Benjamin David, Mona Bafadhel, Leo Koenderman & Antony De Soyza. (2021) Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait. Thorax 76:2, pages 188-195.
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Mario Cazzola, Maria Gabriella Matera & Paola Rogliani. (2021) Blood Eosinophils in Chronic Obstructive Pulmonary Disease: Is There Enough Evidence?. US Respiratory & Pulmonary Diseases 6:1, pages 31.
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Sarah A. Hiles, Peter G. Gibson & Vanessa M. McDonald. (2020) Disease burden of eosinophilic airway disease: Comparing severe asthma, COPD and asthma–COPD overlap . Respirology 26:1, pages 52-61.
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Timothy H. Harries, Victoria Rowland, Christopher J. Corrigan, Iain J. Marshall, Lucy McDonnell, Vibhore Prasad, Peter Schofield, David Armstrong & Patrick White. (2020) Blood eosinophil count, a marker of inhaled corticosteroid effectiveness in preventing COPD exacerbations in post-hoc RCT and observational studies: systematic review and meta-analysis. Respiratory Research 21:1.
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Risa B. BurnsAsha AnandaiahMary B. RiceGerald W. Smetana. (2020) Should You Recommend Inhaled Corticosteroids for This Patient With Chronic Obstructive Pulmonary Disease?. Annals of Internal Medicine 172:11, pages 735-742.
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Dharani Narendra & Nicola A. Hanania. 2020. Cardiovascular Complications of Respiratory Disorders. Cardiovascular Complications of Respiratory Disorders 251 263 .
Hisako Matsumoto. (2020) Approach to management of chronic cough and chronic airway diseases: “Treatable traits” or correct diagnosis?. Respiratory Investigation 58:3, pages 129-130.
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Stanca‐Patricia Hogea, Emanuela Tudorache, Ariadna Petronela Fildan, Ovidiu Fira‐Mladinescu, Monica Marc & Cristian Oancea. (2020) Risk factors of chronic obstructive pulmonary disease exacerbations. The Clinical Respiratory Journal 14:3, pages 183-197.
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Alyn H. Morice, Eva Millqvist, Kristina Bieksiene, Surinder S. Birring, Peter Dicpinigaitis, Christian Domingo Ribas, Michele Hilton Boon, Ahmad Kantar, Kefang Lai, Lorcan McGarvey, David Rigau, Imran Satia, Jacky Smith, Woo-Jung Song, Thomy Tonia, Jan W.K. van den Berg, Mirjam J.G. van Manen & Angela Zacharasiewicz. (2020) ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. European Respiratory Journal 55:1, pages 1901136.
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Amit Frenkel, Eric Kachko, Victor Novack, Moti Klein, Evgeni Brotfain, Leonid Koyfman & Nimrod Maimon. (2019) The Association of Glucocorticosteroid Treatment with WBC Count in Patients with COPD Exacerbation. Journal of Clinical Medicine 8:10, pages 1697.
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Salvatore Fuschillo, Antonio Molino, Cristiana Stellato, Andrea Motta & Mauro Maniscalco. (2019) Blood eosinophils as biomarkers of therapeutic response to chronic obstructive pulmonary disease: Still work in progress. European Journal of Internal Medicine 68, pages 1-5.
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Mario Cazzola, Ermanno Puxeddu, Josuel Ora & Paola Rogliani. (2019) Evolving Concepts in Chronic Obstructive Pulmonary Disease Blood-Based Biomarkers. Molecular Diagnosis & Therapy 23:5, pages 603-614.
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Brianna Atto, Mathew Suji Eapen, Pawan Sharma, Urs Frey, Alaina J. Ammit, James Markos, Collin Chia, Josie Larby, Greg Haug, Heinrich C. Weber, George Mabeza, Stephen Tristram, Stephen Myers, Dominic P. Geraghty, Katie L. Flanagan, Philip M. Hansbro & Sukhwinder Singh Sohal. (2019) New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways. Clinical Science 133:14, pages 1663-1703.
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Sarah H. Landis, Jeanne M. Pimenta, Shibing Yang, Chris Compton, Neil Barnes & Guy Brusselle. (2019) Association between blood eosinophils and acute exacerbation of COPD risk in patients with COPD in primary care. Respiratory Medicine: X 1, pages 100011.
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