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International Journal of Chronic Obstructive Pulmonary Disease Volume 13, 2018 - Issue
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Original Research

miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension

Jing Jiang1 Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s Republic of China
,
Yimeng Xia2 Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People’s Republic of China
,
Yi Liang1 Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s Republic of China
,
Meiling Yang1 Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s Republic of China
,
Wen Zeng1 Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s Republic of China
&
Xiaocong Zeng3 Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s Republic of China, [email protected]Correspondence[email protected]
Pages 3777-3790 | Published online: 20 Nov 2018

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Priya Upadhyay, Ching-Wen Wu, Alexa Pham, Amir A. Zeki, Christopher M. Royer, Urmila P. Kodavanti, Minoru Takeuchi, Hasan Bayram & Kent E. Pinkerton. (2023) Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD). Journal of Toxicology and Environmental Health, Part B 26:5, pages 275-305.
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Zhao Yang, Ping Li, Qun Yuan, Xi Wang, Hong-Hong Ma & Bing Zhuan. (2023) Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1. Respiratory Research 24:1.
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K. Auxzilia Preethi, Sushmaa Chandralekha Selvakumar, Kehinde Ross & Durairaj Sekar. (2022) Therapeutic aspect of microRNA inhibition in various types of hypertension and hypertensive complications. Gene Reports 29, pages 101676.
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Congying Wang, Dong Feng, Shanfeng Dong, Ruilian He & Bosheng Fan. (2022) Dysregulated circulating microRNA‐126 in chronic obstructive pulmonary disease: linkage with acute exacerbation risk, severity degree, and inflammatory cytokines. Journal of Clinical Laboratory Analysis 36:3.
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Hongbin Zang, Qiongyu Zhang & Xiaodong Li. (2021) Non-Coding RNA Networks in Pulmonary Hypertension. Frontiers in Genetics 12.
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Qing Song, Ping Chen & Xiang-Ming Liu. (2021) The role of cigarette smoke-induced pulmonary vascular endothelial cell apoptosis in COPD. Respiratory Research 22:1.
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Shuifang Chen, Yinan Yao, Shan Lu, Junjun Chen, Guangdie Yang, Lingfang Tu & Lina Chen. (2020) CircRNA0001859, a new diagnostic and prognostic biomarkers for COPD and AECOPD. BMC Pulmonary Medicine 20:1.
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Ningjing Ou, Yuxuan Song, Yawei Xu, Yongjiao Yang & Xiaoqiang Liu. (2020) Identification and verification of hub microRNAs in varicocele rats through high-throughput sequencing and bioinformatics analysis. Reproductive Toxicology 98, pages 189-199.
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Takahiro Umehara, Shinichiro Kagawa, Aiko Tomida, Takehiko Murase, Yuki Abe, Keita Shingu & Kazuya Ikematsu. (2020) Body temperature-dependent microRNA expression analysis in rats: rno-miR-374-5p regulates apoptosis in skeletal muscle cells via Mex3B under hypothermia. Scientific Reports 10:1.
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Yue Yu & Xu-Chen Cao. (2019) miR-190-5p in human diseases. Cancer Cell International 19:1.
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Davide Elia, Antonella Caminati, Maurizio Zompatori, Roberto Cassandro, Chiara Lonati, Francesca Luisi, Giuseppe Pelosi, Steeve Provencher & Sergio Harari. (2019) Pulmonary hypertension and chronic lung disease: where are we headed?. European Respiratory Review 28:153, pages 190065.
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Minjing LiWanru CaiYe ChenLei Dong. (2019) The CAV1 Gene 3′ Untranslated Region Single Nucleotide Polymorphisms Are Associated with the Risk of Pulmonary Hypertension in Chinese Han Chronic Obstructive Pulmonary Patients . Genetic Testing and Molecular Biomarkers 23:9, pages 634-643.
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