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International Journal of Chronic Obstructive Pulmonary Disease Volume 15, 2020 - Issue
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Original Research

Th1/Th17 Cytokine Profiles are Associated with Disease Severity and Exacerbation Frequency in COPD Patients

Yan Yu1 Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing100044, People’s Republic of China
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Lili Zhao1 Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing100044, People’s Republic of China
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Yu Xie1 Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing100044, People’s Republic of China
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Yu Xu1 Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing100044, People’s Republic of China
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Weike Jiao2 Department of Pulmonary and Critical Care Medicine, Ningde Municipal Hospital Affiliated to Fujian Medical University, Ningde, Fujian352100, People’s Republic of China
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Jianhui Wu2 Department of Pulmonary and Critical Care Medicine, Ningde Municipal Hospital Affiliated to Fujian Medical University, Ningde, Fujian352100, People’s Republic of China
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Xinyu Deng2 Department of Pulmonary and Critical Care Medicine, Ningde Municipal Hospital Affiliated to Fujian Medical University, Ningde, Fujian352100, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-7948-6896
ORCID Icon,
Guiju Fang2 Department of Pulmonary and Critical Care Medicine, Ningde Municipal Hospital Affiliated to Fujian Medical University, Ningde, Fujian352100, People’s Republic of China
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Qing Xue2 Department of Pulmonary and Critical Care Medicine, Ningde Municipal Hospital Affiliated to Fujian Medical University, Ningde, Fujian352100, People’s Republic of China
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Yali Zheng1 Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing100044, People’s Republic of China;3 Department of Respiratory and Critical Care Medicine, Xiang’An Hospital of Xiamen University, Xiamen, Fujian361100, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-0359-2799
ORCID Icon &
Zhancheng Gao1 Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing100044, People’s Republic of China;3 Department of Respiratory and Critical Care Medicine, Xiang’An Hospital of Xiamen University, Xiamen, Fujian361100, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Pages 1287-1299 | Published online: 08 Jun 2020

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Eduardo I. Cardenas, Karlhans Fru Che, Jon R. Konradsen, Aihua Bao & Anders Lindén. (2022) IL-26 in asthma and COPD. Expert Review of Respiratory Medicine 16:3, pages 293-301.
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Articles from other publishers (10)

Qing Xue, Yu Xie, Yukun He, Yan Yu, Guiju Fang, Wenyi Yu, Jianhui Wu, Jiwei Li, Lili Zhao, Xinyu Deng, Ran Li, Fang Wang, Yali Zheng & Zhancheng Gao. (2023) Lung microbiome and cytokine profiles in different disease states of COPD: a cohort study. Scientific Reports 13:1.
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Hoang Oanh Nguyen, Valentina Salvi, Laura Tiberio, Fabrizio Facchinetti, Mirco Govoni, Gino Villetti, Maurizio Civelli, Ilaria Barbazza, Carolina Gaudenzi, Mauro Passari, Tiziana Schioppa, Francesca Sozio, Annalisa Del Prete, Silvano Sozzani & Daniela Bosisio. (2022) The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation. Journal of Translational Medicine 20:1.
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Katarzyna Leszczyńska, Dominika Jakubczyk & Sabina Górska. (2022) The NLRP3 inflammasome as a new target in respiratory disorders treatment. Frontiers in Immunology 13.
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Lei Wang, Charlotte E. Pelgrim, Lucía N. Peralta Marzal, Stephanie Korver, Ingrid van Ark, Thea Leusink-Muis, Ardy van Helvoort, Ali Keshavarzian, Aletta D. Kraneveld, Johan Garssen, Paul A. J. Henricks, Gert Folkerts & Saskia Braber. (2022) Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis. American Journal of Physiology-Lung Cellular and Molecular Physiology 323:3, pages L266-L280.
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Diana H. Quan, Alexander J. Kwong, Philip M. Hansbro & Warwick J. Britton. (2022) No smoke without fire: the impact of cigarette smoking on the immune control of tuberculosis. European Respiratory Review 31:164, pages 210252.
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Victor Margelidon-Cozzolino, Anne Tsicopoulos, Cécile Chenivesse & Patricia de Nadai. (2022) Role of Th17 Cytokines in Airway Remodeling in Asthma and Therapy Perspectives. Frontiers in Allergy 3.
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Yu Xie, Yan Yu, Lili Zhao, Pu Ning, Qiongzhen Luo, Ying Zhang, Lu Yin, Yali Zheng & Zhancheng Gao. (2021) Specific Cytokine Profiles Predict the Severity of Influenza A Pneumonia: A Prospectively Multicenter Pilot Study. BioMed Research International 2021, pages 1-11.
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Jinding Pu, Juan Xu, Lu Chen, Hongbin Zhou, Weitao Cao, Binwei Hao, Naijian Li, Jianxiong Wu, JinZhen Zheng, Wei Hong, Bing Li & Pixin Ran. (2021) Exposure to biomass smoke induces pulmonary Th17 cell differentiation by activating TLR2 on dendritic cells in a COPD rat model. Toxicology Letters 348, pages 28-39.
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Zhen Chen, Pan Chen, Hao Wu, Rui Shi, Weiwei Su, Yonggang Wang & Peibo Li. (2020) Evaluation of Naringenin as a Promising Treatment Option for COPD Based on Literature Review and Network Pharmacology. Biomolecules 10:12, pages 1644.
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Longchuan Wu, Yu Chen, Jiao Yi, Yi Zhuang, Lei Cui & Chunhui Ye. (2020) Mechanism of Action of Bu-Fei-Yi-Shen Formula in Treating Chronic Obstructive Pulmonary Disease Based on Network Pharmacology Analysis and Molecular Docking Validation. BioMed Research International 2020, pages 1-12.
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