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Original Research

Effects of mometasone furoate/formoterol fumarate fixed-dose combination formulation on chronic obstructive pulmonary disease (COPD): results from a 52-week Phase III trial in subjects with moderate-to-very severe COPD

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Pages 57-71 | Published online: 03 Feb 2012

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Read on this site (11)

Paraschos Archontakis Barakakis, Thuonghien Tran, Jee Young You, Gabriel J Hernandez Romero, Vipul Gidwani, Fernando J Martinez & Spyridon Fortis. (2023) High versus Medium Dose of Inhaled Corticosteroid in Chronic Obstructive Lung Disease: A Systematic Review and Meta-Analysis. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 469-482.
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Gaetano Caramori, Paolo Ruggeri, Fabio Arpinelli, Laura Salvi & Giuseppe Girbino. (2019) Long-term use of inhaled glucocorticoids in patients with stable chronic obstructive pulmonary disease and risk of bone fractures: a narrative review of the literature. International Journal of Chronic Obstructive Pulmonary Disease 14, pages 1085-1097.
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David MG Halpin, Marc Miravitlles, Norbert Metzdorf & Bartolomé Celli. (2017) Impact and prevention of severe exacerbations of COPD: a review of the evidence. International Journal of Chronic Obstructive Pulmonary Disease 12, pages 2891-2908.
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Mingjin Yang, Hong Chen, Yan Zhang, Yuejun Du, Ying Xu, Ping Jiang & Zhibo Xu. (2017) Long-term use of inhaled corticosteroids and risk of upper respiratory tract infection in chronic obstructive pulmonary disease: a meta-analysis. Inhalation Toxicology 29:5, pages 219-226.
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Emir Festic, Vikas Bansal, Ena Gupta & Paul D. Scanlon. (2016) Association of Inhaled Corticosteroids with Incident Pneumonia and Mortality in COPD Patients; Systematic Review and Meta-Analysis. COPD: Journal of Chronic Obstructive Pulmonary Disease 13:3, pages 312-326.
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Morven Wilkie, Simon Finch & Stuart Schembri. (2015) Inhaled Corticosteroids for Chronic Obstructive Pulmonary Disease—The Shifting Treatment Paradigm. COPD: Journal of Chronic Obstructive Pulmonary Disease 12:5, pages 582-590.
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Bhumika Aggarwal & Jaideep Gogtay. (2014) Use of pressurized metered dose inhalers in patients with chronic obstructive pulmonary disease: review of evidence. Expert Review of Respiratory Medicine 8:3, pages 349-356.
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Mario Cazzola, Paola Rogliani, Lucia Novelli & Maria Gabriella Matera. (2013) Inhaled corticosteroids for chronic obstructive pulmonary disease. Expert Opinion on Pharmacotherapy 14:18, pages 2489-2499.
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Ruben D Restrepo, Andrew Tate & Joshua Coquat. (2013) Evaluation of salmeterol xinafoate plus fluticasone propionate for the treatment of chronic obstructive pulmonary disease. Expert Opinion on Pharmacotherapy 14:14, pages 1993-2002.
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Marc L Decramer, Nicola A Hanania, Jan O Lötvall & Barbara P Yawn. (2013) The safety of long-acting β2-agonists in the treatment of stable chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 8, pages 53-64.
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Teddy Kosoglou, James Hubbell, Fengjuan Xuan, David L Cutler, Alan G Meehan, Bhavna Kantesaria & Bret A Wittmer. (2013) Comparison of the systemic bioavailability of mometasone furoate after oral inhalation from a mometasone furoate/formoterol fumarate metered-dose inhaler versus a mometasone furoate dry-powder inhaler in patients with chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 8, pages 107-116.
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Articles from other publishers (24)

Hong Chen, Zheng-Xu Deng, Jian Sun, Qiang Huang, Lan Huang, Yong-Hong He, Chunlan Ma & Ke Wang. (2023) Association of Inhaled Corticosteroids With All-Cause Mortality Risk in Patients With COPD. Chest 163:1, pages 100-114.
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Bernie Y. Sunwoo & Robert L. Owens. (2022) Sleep Deficiency, Sleep Apnea, and Chronic Lung Disease. Clinics in Chest Medicine 43:2, pages 337-352.
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Robert A. Wise, Mona Bafadhel, Courtney Crim, Gerard J. Criner, Nicola C. Day, David M.G. Halpin, MeiLan K. Han, Peter Lange, David A. Lipson, Fernando J. Martinez, Diego J. Maselli, Dawn Midwinter, Dave Singh, Maeva Zysman, Mark T. Dransfield & Richard E.K. Russell. (2021) Discordant diagnostic criteria for pneumonia in COPD trials: a review. European Respiratory Review 30:162, pages 210124.
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Hong Chen, Jian Sun, Qiang Huang, Yongqi Liu, Mengxin Yuan, Chunlan Ma & Hao Yan. (2021) Inhaled Corticosteroids and the Pneumonia Risk in Patients With Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials. Frontiers in Pharmacology 12.
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Hong Chen, Yulin Feng, Ke Wang, Jing Yang & Yuejun Du. (2020) Association between inhaled corticosteroids and upper respiratory tract infection in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials. BMC Pulmonary Medicine 20:1.
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Mingjin Yang, Yuejun Du, Hong Chen, Depeng Jiang & Zhibo Xu. (2019) Inhaled corticosteroids and risk of pneumonia in patients with chronic obstructive pulmonary disease: A meta-analysis of randomized controlled trials. International Immunopharmacology 77, pages 105950.
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Yuji Oba, Edna Keeney, Namratta Ghatehorde & Sofia Dias. (2018) Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis. Cochrane Database of Systematic Reviews 2018:12.
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Jennifer C. Samp, Min J. Joo, Glen T. Schumock, Gregory S. Calip, A. Simon Pickard & Todd A. Lee. (2017) Comparative Effectiveness of Long-Acting Beta 2 -Agonist Combined with a Long-Acting Muscarinic Antagonist or Inhaled Corticosteroid in Chronic Obstructive Pulmonary Disease . Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 37:4, pages 447-455.
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Elaine Yip, Sahar Karimi & Linda T. Pien. (2016) Evaluation of a Therapeutic Interchange from Fluticasone/Salmeterol to Mometasone/Formoterol in Patients with Chronic Obstructive Pulmonary Disease. Journal of Managed Care & Specialty Pharmacy 22:4, pages 316-323.
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Andrew F. Smith, Alexander Klotz & I. Michael Wormstone. (2016) Improving the drug development process by reducing the impact of adverse events: the case of cataracts considered. Drug Discovery Today 21:3, pages 510-516.
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Emir Festic & Paul D. Scanlon. (2015) Incident Pneumonia and Mortality in Patients with Chronic Obstructive Pulmonary Disease. A Double Effect of Inhaled Corticosteroids?. American Journal of Respiratory and Critical Care Medicine 191:2, pages 141-148.
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Jorge Maspero, Ivan Cherrez, Dennis E. Doherty, Donald P. Tashkin, Piotr Kuna, Wen-Ling Kuo, Davis Gates, Hendrik Nolte & Leo T. ChylackJr.Jr.. (2014) Appraisal of lens opacity with mometasone furoate/formoterol fumarate combination in patients with COPD or asthma. Respiratory Medicine 108:9, pages 1355-1362.
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J.A. Wedzicha, D. Singh, J. Vestbo, P.L. Paggiaro, P.W. Jones, F. Bonnet-Gonod, G. Cohuet, M. Corradi, S. Vezzoli, S. Petruzzelli & A. Agusti. (2014) Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations. Respiratory Medicine 108:8, pages 1153-1162.
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Yaa-Hui Dong, Chia-Hsuin Chang, Fe-Lin Lin Wu, Li-Jiuan Shen, Peter M.A. Calverley, Claes-Göran Löfdahl, Mei-Shu Lai & Donald A. Mahler. (2014) Use of Inhaled Corticosteroids in Patients With COPD and the Risk of TB and Influenza. Chest 145:6, pages 1286-1297.
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Teddy Kosoglou, James Hubbell, Bhavna Kantesaria, Mary E. Hanson & David L. Cutler. (2014) An evaluation of the systemic bioavailability of mometasone furoate (MF) after oral inhalation from a MF/formoterol fumarate metered-dose inhaler versus an MF dry-powder inhaler in healthy subjects. Clinical Pharmacology in Drug Development 3:3, pages 229-234.
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Teddy Kosoglou, James Hubbell, Amy O. Johnson-Levonas, Mona Yunan, Bhavna S. Kantesaria & David L. Cutler. (2014) Evaluation of potential for pharmacokinetic interaction between mometasone furoate and formoterol fumarate after oral inhalation from a fixed-dose combination metered-dose inhaler device. Clinical Pharmacology in Drug Development 3:3, pages 222-228.
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Kayleigh M Kew, Sofia Dias & Christopher J Cates. (2014) Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis. Cochrane Database of Systematic Reviews.
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Luis Javier Nannini, Phillippa Poole, Stephen J Milan, Rebecca Holmes & Rebecca Normansell. (2013) Combined corticosteroid and long-acting beta 2 -agonist in one inhaler versus placebo for chronic obstructive pulmonary disease . Cochrane Database of Systematic Reviews 2018:3.
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Kayleigh M Kew, Chris Mavergames & Julia AE Walters. (2013) Long-acting beta 2 -agonists for chronic obstructive pulmonary disease . Cochrane Database of Systematic Reviews.
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C. Compton, D. McBryan, E. Bucchioni & F. Patalano. (2013) The Novartis view on emerging drugs and novel targets for the treatment of chronic obstructive pulmonary disease. Pulmonary Pharmacology & Therapeutics 26:5, pages 562-573.
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Luis Javier Nannini, Phillippa Poole, Stephen J Milan & Annabel Kesterton. (2013) Combined corticosteroid and long-acting beta 2 -agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease . Cochrane Database of Systematic Reviews 2014:6.
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Mark T Dransfield, Sally Lettis, Frank Barnhart, Courtney Crim & Peter M A Calverley. (2013) Fluticasone furoate and vilanterol for COPD – Authors' reply. The Lancet Respiratory Medicine 1:5, pages e21-e22.
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Amir Sharafkhaneh, Suryakanta Velamuri, Jose Melendez, Farah Akhtar & Max Hirshkowitz. (2013) Medical Management of Fatigue. Sleep Medicine Clinics 8:2, pages 265-276.
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Edward M. Kerwin, Catherine Scott-Wilson, Lisa Sanford, Stephen Rennard, Alvar Agusti, Neil Barnes & Courtney Crim. (2013) A randomised trial of fluticasone furoate/vilanterol (50/25 μg; 100/25 μg) on lung function in COPD. Respiratory Medicine 107:4, pages 560-569.
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