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International Journal of Chronic Obstructive Pulmonary Disease Volume 16, 2021 - Issue
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Review

Consistent Pulmonary Drug Delivery with Whole Lung Deposition Using the Aerosphere Inhaler: A Review of the Evidence

Omar S Usmani1 National Heart and Lung Institute (NHLI), Imperial College London, and Royal Brompton Hospital, London, UKORCID Iconhttps://orcid.org/0000-0002-4367-254XView further author information
ORCID Icon,
Nicolas Roche2 Respiratory Medicine, Cochin Hospital, University Paris Descartes, Paris, FranceORCID Iconhttps://orcid.org/0000-0002-3162-5033View further author information
ORCID Icon,
Martin Jenkins3 AstraZeneca, Cambridge, UKView further author information
,
Neda Stjepanovic4 AstraZeneca, Gothenburg, Mölndal, SwedenORCID Iconhttps://orcid.org/0000-0002-5688-4728View further author information
ORCID Icon,
Peter Mack5 AstraZeneca, Durham, NC, USAView further author information
&
Wilfried De Backer6 Department of Pulmonary Medicine, Faculty of Medicine, University of Antwerp, Antwerp, BelgiumCorrespondence[email protected]
View further author information
Pages 113-124 | Published online: 18 Jan 2021

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Daiana Stolz, Erik Hermansson, Mario Ouwens, Barinder Singh, Akanksha Sharma, Dan Jackson, Patrick Darken, Jonathan Marshall, Karin Bowen, Hana Müllerová, Bernardino Alcázar Navarrete, Richard Russell, MeiLan K. Han & Deniz Tansey-Dwyer. (2023) Mortality risk reduction with budesonide/glycopyrrolate/formoterol fumarate versus fluticasone furoate/umeclidinium/vilanterol in COPD: a matching-adjusted indirect comparison based on ETHOS and IMPACT. Current Medical Research and Opinion 0:0, pages 1-11.
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Conor A. Ruzycki, Derek Montoya, Hammad Irshad, Jason Cox, Yue Zhou, Jacob D. McDonald & Philip J. Kuehl. (2023) Inhalation delivery of nucleic acid gene therapies in preclinical drug development. Expert Opinion on Drug Delivery 20:8, pages 1097-1113.
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Mario Cazzola, Paola Rogliani, Silvio Naviglio, Luigino Calzetta & Maria Gabriella Matera. (2022) An update on the currently available and emerging synthetic pharmacotherapy for uncontrolled asthma. Expert Opinion on Pharmacotherapy 23:10, pages 1205-1216.
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Fiammetta Danzo, Dejan Radovanovic, Marina Gatti, Marina Saad, Luca Perotto, Elisa Franceschi & Pierachille Santus. (2022) A reappraisal of inspiratory capacity in chronic obstructive pulmonary disease: clinical correlates and role of long-acting muscarinic antagonists and long-acting β2 agonists. Expert Review of Respiratory Medicine 16:6, pages 623-635.
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Articles from other publishers (9)

Bradley E. Chipps, Elliot Israel, Richard Beasley, Reynold A. PanettieriJr.Jr., Frank C. Albers, Robert Rees, Lynn Dunsire, Anna Danilewicz, Eva Johnsson, Christy Cappelletti & Alberto Papi. (2023) Albuterol-Budesonide Pressurized Metered Dose Inhaler in Patients With Mild-to-moderate Asthma. CHEST.
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Somchai Sawatdee, Narumon Changsan, Teerapol Srichana & Basavaraj Nanjwade. 2023. Pulmonary Drug Delivery Systems: Material and Technological Advances. Pulmonary Drug Delivery Systems: Material and Technological Advances 131 175 .
Ji-Hyun Kang, Min-Seok Yang, Taek Kwan Kwon, Dong-Wook Kim & Chun-Woong Park. (2022) Inhaled deep eutectic solvent based-nanoemulsion of pirfenidone in idiopathic pulmonary fibrosis. Journal of Controlled Release 352, pages 570-585.
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Abhinav Ram Mohan, Qiang Wang, Sneha Dhapare, Elizabeth Bielski, Anubhav Kaviratna, Liangfeng Han, Susan Boc & Bryan Newman. (2022) Advancements in the Design and Development of Dry Powder Inhalers and Potential Implications for Generic Development. Pharmaceutics 14:11, pages 2495.
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Alberto PapiBradley E. ChippsRichard Beasley, Reynold A. PanettieriJr.Jr., Elliot IsraelMark CooperLynn DunsireAllison Jeynes-EllisEva JohnssonRobert ReesChristy CappellettiFrank C. Albers. (2022) Albuterol–Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma. New England Journal of Medicine 386:22, pages 2071-2083.
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E. A. Orlova, I. P. Dorfman, M. A. Orlov & M. A. Abdullaev. (2022) The double bronchodilation era: new capabilities in a new drug delivery device. Meditsinskiy sovet = Medical Council:4, pages 128-137.
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Craig LaForce, Bradley E. Chipps, Frank C. Albers, Laurence Reilly, Eva Johnsson, Helen Andrews, Christy Cappelletti, Andrea Maes & Alberto Papi. (2022) Albuterol/budesonide for the treatment of exercise-induced bronchoconstriction in patients with asthma. Annals of Allergy, Asthma & Immunology 128:2, pages 169-177.
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Paschalis Steiropoulos, Petros Bakakos, Elpis Hatziagorou, Paraskevi Katsaounou, Stelios Loukides, Andriana Papaioannou, Konstantinos Porpodis, Konstantinos Samaras, Argyrios Tzouvelekis, Konstantinos Kalafatakis & Konstantinos Kostikas. (2021) The present and future of inhalation therapy for the management of obstructive airway diseases: Emphasis on pressurized metered-dose inhalers. Pneumon, pages 1-13.
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Bradley E Chipps, Frank C Albers, Laurence Reilly, Eva Johnsson, Christy Cappelletti & Alberto Papi. (2021) Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study. BMJ Open Respiratory Research 8:1, pages e001077.
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