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Original Research

Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note

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Pages 127-135 | Published online: 23 Feb 2012

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Read on this site (4)

Wentao Ni, Jing Bao, Donghong Yang, Wen Xi, Keqiang Wang, Yu Xu, Rongbao Zhang & Zhancheng Gao. (2019) Potential of serum procalcitonin in predicting bacterial exacerbation and guiding antibiotic administration in severe COPD exacerbations: a systematic review and meta-analysis. Infectious Diseases 51:9, pages 639-650.
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Justin J. Choi & Matthew W. McCarthy. (2018) Novel applications for serum procalcitonin testing in clinical practice. Expert Review of Molecular Diagnostics 18:1, pages 27-34.
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Chih-Hao Chang, Kuo-Chien Tsao, Han-Chung Hu, Chung-Chi Huang, Kuo-Chin Kao, Ning-Hung Chen, Cheng-Ta Yang, Ying-Huang Tsai & Meng-Jer Hsieh. (2015) Procalcitonin and C-reactive protein cannot differentiate bacterial or viral infection in COPD exacerbation requiring emergency department visits. International Journal of Chronic Obstructive Pulmonary Disease 10, pages 767-774.
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Robert A Stockley. (2014) Biomarkers in chronic obstructive pulmonary disease: confusing or useful?. International Journal of Chronic Obstructive Pulmonary Disease 9, pages 163-177.
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Articles from other publishers (28)

George Hoult, David Gillespie, Tom M. A. Wilkinson, Mike Thomas & Nick A. Francis. (2022) Biomarkers to guide the use of antibiotics for acute exacerbations of COPD (AECOPD): a systematic review and meta-analysis. BMC Pulmonary Medicine 22:1.
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Yan-Ping Ye, Hang Zhao, Tao Kang, Li-Hua Zhao, Ning Li, Jing Chen & Xiao-Xia Peng. (2022) Optimal cut-off value of serum procalcitonin in predicting bacterial infection induced acute exacerbation in chronic obstructive pulmonary disease: A prospective observational study. Chronic Respiratory Disease 19, pages 147997312211085.
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Piroska Pázmány, Alexandra Soós, Péter Hegyi, Dóra Dohos, Szabolcs Kiss, Zsolt Szakács, Andrea Párniczky, András Garami, Zoltán Péterfi & Zsolt Molnár. (2021) Inflammatory Biomarkers Are Inaccurate Indicators of Bacterial Infection on Admission in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease—A Systematic Review and Diagnostic Accuracy Network Meta-Analysis. Frontiers in Medicine 8.
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Takaaki Kishino, Nobuhiro Asai, Wataru Ohashi, Daisuke Sakanashi, Hideo Kato, Arufumi Shiota, Mao Hagihara, Yusuke Koizumi, Yuka Yamagishi, Hiroyuki Suematsu, Hideki Kano, Naoshi Takeyama & Hiroshige Mikamo. (2021) Usefulness of serum procalcitonin for necrotizing fasciitis as an early diagnostic tool. Journal of Infection and Chemotherapy 27:6, pages 787-793.
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倩倩 陈. (2021) Evaluation of Serum PCT, CRP, and SAA for COPD. Advances in Clinical Medicine 11:05, pages 2228-2232.
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Ernesto Crisafulli, Alessandra Manco, Miquel Ferrer, Arturo Huerta, Claudio Micheletto, Domenico Girelli, Enrico Clini & Antoni Torres. (2020) Pneumonic versus Nonpneumonic Exacerbations of Chronic Obstructive Pulmonary Disease. Seminars in Respiratory and Critical Care Medicine 41:06, pages 817-829.
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Ken Chen, Katherine A. Pleasants, Roy A. Pleasants, Tatsiana Beiko, Ronald G. Washburn, Zhiheng Yu, Suodi Zhai & M. Bradley Drummond. (2020) Procalcitonin for Antibiotic Prescription in Chronic Obstructive Pulmonary Disease Exacerbations: Systematic Review, Meta-Analysis, and Clinical Perspective. Pulmonary Therapy 6:2, pages 201-214.
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Han Jin, Shengwen Yang, Pengkang He, Haoyu Weng, Shengcong Liu, Fan Yang, Long Zhang, Fangfang Fan, Yan Zhang, Jing Zhou & Jianping Li. (2020) Serum Procalcitonin Levels on Admission Predict Death in Severe and Critical COVID-19 Patients in Wuhan, China. Cardiovascular Innovations and Applications 5:1.
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Yuliang Zhao, Fei Li, Yangwen Liu, Yingjun Shi, Zhihai Li, Guangke Cao & Wang Zhu. (2018) Comparison of efficiency of inhaled and intravenous corticosteroid on pregnant women with COPD and the effects on the expression of PCT and hs-CRP. Experimental and Therapeutic Medicine.
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Changyang Lin & Qiyuan Pang. (2018) Meta-analysis and systematic review of procalcitonin-guided treatment in acute exacerbation of chronic obstructive pulmonary disease. The Clinical Respiratory Journal 12:1, pages 10-15.
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Christopher F. Lowe, Michael Payne, David Puddicombe, Allison Mah, Davie Wong, Allison Kirkwood, Mark W. Hull & Victor Leung. (2017) Antimicrobial stewardship for hospitalized patients with viral respiratory tract infections. American Journal of Infection Control 45:8, pages 872-875.
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Alexander G. Mathioudakis, Victoria Chatzimavridou-Grigoriadou, Alexandru Corlateanu & Jørgen Vestbo. (2017) Procalcitonin to guide antibiotic administration in COPD exacerbations: a meta-analysis. European Respiratory Review 26:143, pages 160073.
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G.-J. M. van de Geijn, S. Denker, V. Meuleman-van Waning, H. G. M. Koeleman, E. Birnie, G.-J. Braunstahl & T. L. Njo. (2016) Evaluation of new laboratory tests to discriminate bacterial from nonbacterial chronic obstructive pulmonary disease exacerbations. International Journal of Laboratory Hematology 38:6, pages 616-628.
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Ali Taghizadieh, Hassan Soleimanpour, Farzad Rahmani, Kavous Shahsavari Nia & Hossein Khodaverdizadeh. (2016) Comparison of Serum Levels of Procalcitonin and C-Reactive Protein in Patients with Community Acquired Pneumonia and COPD Exacerbation. Iranian Red Crescent Medical Journal 18:12.
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Anokhi J. Kapasi, Sabine Dittrich, Iveth J. González & Timothy C. Rodwell. (2016) Host Biomarkers for Distinguishing Bacterial from Non-Bacterial Causes of Acute Febrile Illness: A Comprehensive Review. PLOS ONE 11:8, pages e0160278.
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Yu-Wei Roy Chen, Janice M. Leung & Don D. Sin. (2016) A Systematic Review of Diagnostic Biomarkers of COPD Exacerbation. PLOS ONE 11:7, pages e0158843.
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Lu Yun, Jin Wei, Zhang Hong & Zhang Xiaoyun. (2016) Multicenter clinical efficacy observation of integrated Traditional Chinese Medicine-Western Medicine treatment in acute onset period of pulmonary heart disease. Journal of Traditional Chinese Medicine 36:3, pages 283-290.
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Michael S. Abers, Barcleigh P. Sandvall, Rahul Sampath, Carlo Zuno, Natalie Uy, Victor L. Yu, Charles E. Stager & Daniel M. Musher. (2016) Postobstructive Pneumonia: An Underdescribed Syndrome. Clinical Infectious Diseases 62:8, pages 957-961.
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Jose Luis Lopez-Campos, Carmen Calero-Acuña, Cecilia Lopez-Ramirez, María Abad-Arranz, Eduardo Márquez-Martín, Francisco Ortega-Ruiz & Elena Arellano. (2016) Implications of the inflammatory response for the identification of biomarkers of chronic obstructive pulmonary disease. Biomarkers in Medicine 10:2, pages 109-122.
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David N. Gilbert. (2015) Where Do We Go From Here?. Journal of Infectious Diseases 212:11, pages 1687-1689.
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Gita Gelfer, James Leggett, Jillian Myers, Luan Wang & David N. Gilbert. (2015) The clinical impact of the detection of potential etiologic pathogens of community-acquired pneumonia. Diagnostic Microbiology and Infectious Disease 83:4, pages 400-406.
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Jose Luis Lopez-Campos & Alvar Agustí. (2015) Heterogeneity of chronic obstructive pulmonary disease exacerbations: a two-axes classification proposal. The Lancet Respiratory Medicine 3:9, pages 729-734.
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Tristan Timbrook, Meshell Maxam & John Bosso. (2015) Antibiotic Discontinuation Rates Associated with Positive Respiratory Viral Panel and Low Procalcitonin Results in Proven or Suspected Respiratory Infections. Infectious Diseases and Therapy 4:3, pages 297-306.
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M. Dres, A. Ferre & O. Sanchez. (2014) Scompenso respiratorio delle broncopneumopatie croniche ostruttive. EMC - Anestesia-Rianimazione 19:4, pages 1-10.
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M. Dres, A. Ferre & O. Sanchez. (2014) Descompensación respiratoria de la enfermedad pulmonar obstructiva crónica. EMC - Anestesia-Reanimación 40:4, pages 1-11.
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Takayuki Hoshina, Etsuro Nanishi, Shunsuke Kanno, Hisanori Nishio, Koichi Kusuhara & Toshiro Hara. (2014) The utility of biomarkers in differentiating bacterial from non-bacterial lower respiratory tract infection in hospitalized children: Difference of the diagnostic performance between acute pneumonia and bronchitis. Journal of Infection and Chemotherapy 20:10, pages 616-620.
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Arturo Huerta, Ernesto Crisafulli, Rosario Menéndez, Raquel Martínez, Néstor Soler, Mónica Guerrero, Beatriz Montull & Antoni Torres. (2013) Pneumonic and Nonpneumonic Exacerbations of COPD. Chest 144:4, pages 1134-1142.
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Benjamin L. Nicholas. (2013) Search for biomarkers in chronic obstructive pulmonary disease. Current Opinion in Pulmonary Medicine 19:2, pages 103-108.
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