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Review

Symptom variability in COPD: a narrative review

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Pages 231-238 | Published online: 07 May 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (13)

Donald A Mahler, Henrik Watz, Rachel Emerson-Stadler, John Ritz, Asparuh Gardev, Asif Shaikh & M Bradley Drummond. (2023) Clinical Implications of Peak Inspiratory Flow in COPD: Post Hoc Analyses of the TRONARTO Study. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 1729-1740.
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Donald A Mahler, Andrea Ludwig-Sengpiel, Gary T Ferguson, Alberto de la Hoz, John Ritz, Asif Shaikh & Henrik Watz. (2021) TRONARTO: A Randomized, Placebo-Controlled Study of Tiotropium/Olodaterol Delivered via Soft Mist Inhaler in COPD Patients Stratified by Peak Inspiratory Flow. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 2455-2465.
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Silvia Uccelli, Laura Pini, Damiano Bottone, Piera Ranieri, Nicla Orzes & Claudio Tantucci. (2020) Dyspnea During Night-Time and at Early Morning in Patients with Stable COPD is Associated with Supine Tidal Expiratory Flow Limitation. International Journal of Chronic Obstructive Pulmonary Disease 15, pages 2549-2558.
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Nurdan Kokturk, Wael Abuharbid, Amr S Albanna, Hakan Gunen, Alev Gurgun, Mousa Khadadah, Elmas Malvolti, Medhat Soliman, Richard van Zyl-Smit, Noureddine Zidouni & Ashraf Alzaabi. (2019) A Cross-Sectional Study in Patients with Severe COPD to Assess the Perception of Symptom Variability (COPVAR) in the Middle East and Africa. International Journal of Chronic Obstructive Pulmonary Disease 14, pages 2959-2970.
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Mi-Ae Kim, Min-Kang Suh, Jisoo Park, Jung-Hyun Kim, Tae-Hoon Kim, Eun Kyung Kim, Yeon-Mok Oh, Sang-Do Lee & Ji-Hyun Lee. (2019) Impact of symptom variability on clinical outcomes in COPD: analysis of a longitudinal cohort. International Journal of Chronic Obstructive Pulmonary Disease 14, pages 2135-2144.
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Kate M Johnson, Abdollah Safari, Wan C Tan, Jean Bourbeau, J Mark FitzGerald, Mohsen Sadatsafavi & On behalf of the Canadian Cohort of Obstructive Lung Disease (CanCOLD) study. (2018) Heterogeneity in the respiratory symptoms of patients with mild-to-moderate COPD. International Journal of Chronic Obstructive Pulmonary Disease 13, pages 3983-3995.
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Asha Hareendran, Barry J Make, Erica Zaiser & Esther Garcia Gil. (2018) Evaluation of the psychometric properties of the Early Morning Symptoms of COPD Instrument (EMSCI). International Journal of Chronic Obstructive Pulmonary Disease 13, pages 1633-1645.
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Johannes Krönig, Olaf Hildebrandt, Andreas Weissflog, Werner Cassel, Volker Gross, Keywan Sohrabi, Patrick Fischer & Ulrich Koehler. (2017) Long-term Recording of Night-Time Respiratory Symptoms in Patients with Stable COPD II–IV. COPD: Journal of Chronic Obstructive Pulmonary Disease 14:5, pages 498-503.
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Amanda R. van Buul, Marise J. Kasteleyn, Niels H. Chavannes & Christian Taube. (2017) Morning symptoms in COPD: a treatable yet often overlooked factor. Expert Review of Respiratory Medicine 11:4, pages 311-322.
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Wei-Chun Lin, Tsuey-Yuan Huang, Chieh-Yu Liu, Mei-Ling Yeh, Chia-Hui Yu & Shiow-Li Hwang. (2016) Validation of the Clinical COPD Questionnaire in Taiwan. COPD: Journal of Chronic Obstructive Pulmonary Disease 13:3, pages 360-366.
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Maria Gabriella Matera, Alessandro Sanduzzi & Mario Cazzola. (2016) Specific role of combination aclidinium: formoterol in the treatment of chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 11, pages 73-79.
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Judith J Stephenson, Qian Cai, Michelle Mocarski, Hiangkiat Tan, Jalpa A Doshi & Sean D Sullivan. (2015) Impact and factors associated with nighttime and early morning symptoms among patients with chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 10, pages 577-586.
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Jose Luis Lopez-Campos, Víctor Bustamante, Xavier Muñoz & Esther Barreiro. (2014) Moving Towards Patient-Centered Medicine for COPD Management: Multidimensional Approaches versus Phenotype-Based Medicine—A Critical View. COPD: Journal of Chronic Obstructive Pulmonary Disease 11:5, pages 591-602.
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Saeid Safiri, Kristin Carson-Chahhoud, Maryam Noori, Seyed Aria Nejadghaderi, Mark J M Sullman, Javad Ahmadian Heris, Khalil Ansarin, Mohammad Ali Mansournia, Gary S Collins, Ali-Asghar Kolahi & Jay S Kaufman. (2022) Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019. BMJ, pages e069679.
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Mohit Bhutani, David B. Price, Tonya A. Winders, Heinrich Worth, Kevin Gruffydd-Jones, Ruth Tal-Singer, Jaime Correia-de-Sousa, Mark T. Dransfield, Rudi Peché, Daiana Stolz & John R. Hurst. (2022) Quality Standard Position Statements for Health System Policy Changes in Diagnosis and Management of COPD: A Global Perspective. Advances in Therapy 39:6, pages 2302-2322.
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Narongkorn Saiphoklang, Apiwat Pugongchai & Kanyada Leelasittikul. (2022) Comparison between 20 and 30 meters in walkway length affecting the 6-minute walk test in patients with chronic obstructive pulmonary disease: A randomized crossover study. PLOS ONE 17:1, pages e0262238.
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Danielle A. Baxter, Johannah L. Shergis, Catherine J. Hill, Christopher Worsnop & Meaghan E. Coyle. (2021) Perceptions and experiences of a manual therapy trial: a qualitative study of people with moderate to severe COPD. Chiropractic & Manual Therapies 29:1.
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Sang Hyuk Kim, Hyun Lee & Youlim Kim. (2021) Health-related quality of life after pulmonary tuberculosis in South Korea: analysis from the Korea National Health and Nutrition Examination Survey between 2010 and 2018. Health and Quality of Life Outcomes 19:1.
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Theresa A. Koleck, Maxim Topaz, Nicholas P. Tatonetti, Maureen George, Christine Miaskowski, Arlene Smaldone & Suzanne Bakken. (2021) Characterizing shared and distinct symptom clusters in common chronic conditions through natural language processing of nursing notes. Research in Nursing & Health 44:6, pages 906-919.
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John R. Hurst, Tonya Winders, Heinrich Worth, Mohit Bhutani, Kevin Gruffydd-Jones, Daiana Stolz & Mark T. Dransfield. (2020) A Patient Charter for Chronic Obstructive Pulmonary Disease. Advances in Therapy 38:1, pages 11-23.
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Alan Davies, Julia Mueller, Jean Hennings, Ann-Louise Caress & Caroline Jay. (2020) Recommendations for Developing Support Tools With People Suffering From Chronic Obstructive Pulmonary Disease: Co-Design and Pilot Testing of a Mobile Health Prototype. JMIR Human Factors 7:2, pages e16289.
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Ioanna Tsiligianni & Janwillem W. H. Kocks. (2020) Daytime symptoms of chronic obstructive pulmonary disease: a systematic review. npj Primary Care Respiratory Medicine 30:1.
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Lloyd Tanner & Andrew Bruce Single. (2020) Animal Models Reflecting Chronic Obstructive Pulmonary Disease and Related Respiratory Disorders: Translating Pre-Clinical Data into Clinical Relevance. Journal of Innate Immunity 12:3, pages 203-225.
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M. G. Matera, C. P. Page, L. Calzetta, P. Rogliani & M. Cazzola. (2019) Pharmacology and Therapeutics of Bronchodilators Revisited. Pharmacological Reviews 72:1, pages 218-252.
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Ellen Ingrid Schafheutle, Tom Fegan & Darren M. Ashcroft. (2018) Exploring medicines management by COPD patients and their social networks after hospital discharge. International Journal of Clinical Pharmacy 40:5, pages 1019-1029.
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Thomas Kronborg, Lasse Mark, Simon Lebech Cichosz, Pernille Heyckendorff Secher & Ole Hejlesen. (2018) Population exacerbation incidence contains predictive information of acute exacerbations in patients with chronic obstructive pulmonary disease in telecare. International Journal of Medical Informatics 111, pages 72-76.
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Camilla A Mousing, Helle Timm, Kirsten Lomborg & Marit Kirkevold. (2018) Barriers to palliative care in people with chronic obstructive pulmonary disease in home care: A qualitative study of the perspective of professional caregivers. Journal of Clinical Nursing 27:3-4, pages 650-660.
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Marc Miravitlles, Ana Menezes, Maria Victorina López Varela, Alejandro Casas, Luis Ugalde, Alejandra Ramirez-Venegas, Laura Mendoza, Ana López, Fernando C. Wehrmeister, Filip Surmont & Maria Montes de Oca. (2018) Prevalence and impact of respiratory symptoms in a population of patients with COPD in Latin America: The LASSYC observational study. Respiratory Medicine 134, pages 62-69.
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Marc Miravitlles & Anna Ribera. (2017) Understanding the impact of symptoms on the burden of COPD. Respiratory Research 18:1.
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F. Blasi, G. W. Canonica & M. Miravitlles. (2017) Is aclidinium alone or combined with a LABA a rational choice for symptomatic COPD patients?. Respiratory Research 18:1.
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Marc Miravitlles, José Luis Izquierdo, Cristina Esquinas, Maite Pérez, Myriam Calle, José Luis López-Campos, José Miguel Rodríguez González-Moro, Ciro Casanova, Cristóbal Esteban & Pilar de Lucas. (2017) The variability of respiratory symptoms and associated factors in COPD. Respiratory Medicine 129, pages 165-172.
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Cecilia López Ramírez, Carmen Calero Acuña, Cristina Represas Represas, Luz Aballe Santos, Ricard Casamor, Alberto Fernández-Villar & José Luis López-Campos. (2017) Evaluation of the visit frequency and the use of questionnaires and indices for COPD: a national survey from the On-Sint study. The Clinical Respiratory Journal 11:3, pages 367-373.
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Fabiano Di Marco, Pierachille Santus, Nicola Scichilone, Paolo Solidoro, Marco Contoli, Fulvio Braido & Angelo Guido Corsico. (2017) Symptom variability and control in COPD: Advantages of dual bronchodilation therapy. Respiratory Medicine 125, pages 49-56.
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Amanda R. van Buul, Marise J. Kasteleyn, Niels H. Chavannes & Christian Taube. (2017) Association between morning symptoms and physical activity in COPD: a systematic review. European Respiratory Review 26:143, pages 160033.
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Zhi-hua Zhu, Tao Liu, Bo Cong & Fengping Liu. 2017. Wearable Sensors and Robots. Wearable Sensors and Robots 251 262 .
Gary Globe, Brooke Currie, Nancy Kline Leidy, Paul Jones, David Mannino, Fernando Martinez, Paul Klekotka, Sean O’Quinn, Niklas Karlsson & Ingela Wiklund. (2016) Development of the chronic obstructive pulmonary disease morning symptom diary (COPD-MSD). Health and Quality of Life Outcomes 14:1.
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Ioanna Tsiligianni, Esther Metting, Thys van der Molen, Niels Chavannes & Janwillem Kocks. (2016) Morning and night symptoms in primary care COPD patients: a cross-sectional and longitudinal study. An UNLOCK study from the IPCRG. npj Primary Care Respiratory Medicine 26:1.
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E. Kelkel, F. Herengt, H. Ben Saidane, D. Veale, C. Jeanjean, C. Pison, J. Pernot, J.-L. Pépin, B. Guillaud-Segard, J. Gonzalez-Bermejo & B. Aguilaniu. (2016) COLIBRI : optimiser la pratique clinique et produire des données scientifiques pertinentes. Revue des Maladies Respiratoires 33:1, pages 5-16.
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N K Leidy, C C Sexton, P W Jones, S M Notte, B U Monz, L Nelsen, M Goldman, L T Murray & S Sethi. (2014) Measuring respiratory symptoms in clinical trials of COPD: reliability and validity of a daily diary. Thorax 69:5, pages 424-430.
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