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Review

Cabozantinib in the treatment of advanced renal cell carcinoma: design, development, and potential place in the therapy

Paolo GrassiDepartment of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto nazionale Tumori, Milan, Italy

Elena VerzoniDepartment of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto nazionale Tumori, Milan, Italy

Raffaele RattaDepartment of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto nazionale Tumori, Milan, Italy

Alessia MennittoDepartment of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto nazionale Tumori, Milan, Italy

Filippo de BraudDepartment of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto nazionale Tumori, Milan, Italy

Giuseppe ProcopioDepartment of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto nazionale Tumori, Milan, ItalyCorrespondence[email protected]

Pages 2167-2172 | Published online: 05 Jul 2016

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Takashi Nakagawa, Toshiki Kijima, Naoki Imasato, Akihiko Nagoshi, Gaku Nakamura, Toshitaka Uematsu, Issei Suzuki, Daisaku Nishihara & Takao Kamai. (2022) Efficacy of cabozantinib therapy for brain metastases from renal cell carcinoma. IJU Case Reports 5:4, pages 293-296.
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Aphrothiti J. Hanrahan, Gopa Iyer & David B. Solit. 2020. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 24 46.e12 .

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Michele Prisciandaro, Raffaele Ratta, Francesco Massari, Giuseppe Fornarini, Salvatore Caponnetto, Roberto Iacovelli, Ugo De Giorgi, Gaetano FacchiniSarah Scagliarini, Roberto Sabbatini, Claudia Caserta, Giorgia Peverelli, Alessia Mennitto, Elena Verzoni & Giuseppe Procopio. (2019) Safety and Efficacy of Cabozantinib for Metastatic Nonclear Renal Cell Carcinoma. American Journal of Clinical Oncology 42:1, pages 42-45.
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Wagner Ricardo Montor, Andrei Ronaldo Oliveira Silva Escar Salas & Fabiana Henriques Machado de Melo. (2018) Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors. Molecular Cancer 17:1.
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Raffaele Ratta, Elena Verzoni, Massimo Di Maio, Paolo Grassi, Maurizio Colecchia, Giovanni Fucà, Filippo de Braud & Giuseppe Procopio. (2018) Exposure to Multiple Lines of Treatment and Survival of Patients With Metastatic Renal Cell Carcinoma: A Real-world Analysis. Clinical Genitourinary Cancer 16:4, pages e735-e742.
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Hong-Ling He & Wan-Xia Yao. (2017) A network meta-analysis of short-term efficacy of different single-drug targeted therapies in the treatment of renal cell carcinoma. Bioscience Reports 37:6.
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Urs B. Hagemann, Dessislava Mihaylova, Steinar R. Uran, Joergen Borrebaek, Derek Grant, Roger M. Bjerke, Jenny Karlsson & Alan S. Cuthbertson. (2017) Targeted alpha therapy using a novel CD70 targeted thorium-227 conjugate in in vitro and in vivo models of renal cell carcinoma . Oncotarget 8:34, pages 56311-56326.
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Uwe Fricke, Lutz Hein & Ulrich Schwabe. 2017. Arzneiverordnungs-Report 2017. Arzneiverordnungs-Report 2017 55 135 .

Zaina T. Al-Salama & Gillian M. Keating. (2016) Cabozantinib: A Review in Advanced Renal Cell Carcinoma. Drugs 76:18, pages 1771-1778.
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Cabozantinib in the treatment of advanced renal cell carcinoma: design, development, and potential place in the therapy

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