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Drug Design, Development and Therapy Volume 11, 2017 - Issue
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Review

Spotlight on mavrilimumab for the treatment of rheumatoid arthritis: evidence to date

Chiara Crotti1 Department of Clinical Sciences and Health Community, University of Milan, Division of Rheumatology, Gaetano Pini Institute
,
Maria Gabriella Raimondo1 Department of Clinical Sciences and Health Community, University of Milan, Division of Rheumatology, Gaetano Pini Institute
,
Andrea Becciolini2 Department of Rheumatology, Gaetano Pini Institute, Milan, Italy
,
Martina Biggioggero1 Department of Clinical Sciences and Health Community, University of Milan, Division of Rheumatology, Gaetano Pini Institute
&
Ennio Giulio Favalli2 Department of Rheumatology, Gaetano Pini Institute, Milan, ItalyCorrespondence[email protected]
Pages 211-223 | Published online: 13 Jan 2017

Citations (15)

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Read on this site (3)

Chiara Crotti, Martina Biggioggero, Andrea Becciolini, Elena Agape & Ennio Giulio Favalli. (2019) Mavrilimumab: a unique insight and update on the current status in the treatment of rheumatoid arthritis. Expert Opinion on Investigational Drugs 28:7, pages 573-581.
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Urmi Dhagat, Timothy R. Hercus, Sophie E. Broughton, Tracy L. Nero, Karen S. Cheung Tung Shing, Emma F. Barry, Christy A. Thomson, Steve Bryson, Emil F. Pai, Barbara J. McClure, John W. Schrader, Angel F. Lopez & Michael W. Parker. (2018) The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities. mAbs 10:7, pages 1018-1029.
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Maria Gabriella Raimondo, Martina Biggioggero, Chiara Crotti, Andrea Becciolini & Ennio Giulio Favalli. (2017) Profile of sarilumab and its potential in the treatment of rheumatoid arthritis. Drug Design, Development and Therapy 11, pages 1593-1603.
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Articles from other publishers (12)

Peeyush Prasad, Sneha Verma, Surbhi, Nirmal Kumar Ganguly, Ved Chaturvedi & Shivani Arora Mittal. (2022) Rheumatoid arthritis: advances in treatment strategies. Molecular and Cellular Biochemistry 478:1, pages 69-88.
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Lianying Cheng, Jie Chen & Xiaofeng Rong. (2022) Mechanism of Emodin in the Treatment of Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-16.
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Maria Petrina, Jacqueline Martin & Sameh Basta. (2021) Granulocyte macrophage colony-stimulating factor has come of age: From a vaccine adjuvant to antiviral immunotherapy. Cytokine & Growth Factor Reviews 59, pages 101-110.
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Jinsha Liu, Joey Paolo Ting, Shams Al-Azzam, Yun Ding & Sepideh Afshar. (2021) Therapeutic Advances in Diabetes, Autoimmune, and Neurological Diseases. International Journal of Molecular Sciences 22:6, pages 2805.
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Yuan Zhang, Jonathan Aldridge, Georgios K. Vasileiadis, Helena Edebo, Anna-Karin H. Ekwall, Anna-Carin Lundell, Anna Rudin & Cristina Maglio. (2021) Recombinant Adiponectin Induces the Production of Pro-Inflammatory Chemokines and Cytokines in Circulating Mononuclear Cells and Fibroblast-Like Synoviocytes From Non-Inflamed Subjects. Frontiers in Immunology 11.
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Zhaonian Hao, Ruyuan Li, Li Meng, Zhiqiang Han & Zhenya Hong. (2020) Macrophage, the potential key mediator in CAR-T related CRS. Experimental Hematology & Oncology 9:1.
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Chintana Chirathaworn, Jira Chansaenroj & Yong Poovorawan. (2020) Cytokines and Chemokines in Chikungunya Virus Infection: Protection or Induction of Pathology. Pathogens 9:6, pages 415.
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Chiara Crotti, Elena Agape, Andrea Becciolini, Martina Biggioggero & Ennio Giulio Favalli. (2019) Targeting Granulocyte-Monocyte Colony-Stimulating Factor Signaling in Rheumatoid Arthritis: Future Prospects. Drugs 79:16, pages 1741-1755.
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Rosalie M. SternerReona Sakemura, Michelle J. Cox, Nan Yang, Roman H. KhadkaCynthia L. Forsman, Michael J. HansenFang JinKatayoun AyasoufiMehrdad Hefazi, Kendall J. Schick, Denise K. WaltersOmar Ahmed, Dale Chappell, Tarek Sahmoud, Cameron Durrant, Wendy K. NevalaMrinal M. Patnaik, Larry R. PeaseKaren E. HedinNeil E. Kay, Aaron J. JohnsonSaad S. Kenderian. (2019) GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood 133:7, pages 697-709.
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Hooi-Yeen Yap, Sabrina Tee, Magdelyn Wong, Sook-Khuan Chow, Suat-Cheng Peh & Sin-Yeang Teow. (2018) Pathogenic Role of Immune Cells in Rheumatoid Arthritis: Implications in Clinical Treatment and Biomarker Development. Cells 7:10, pages 161.
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Gerd R. Burmester, Iain B. McInnes, Joel M. Kremer, Pedro Miranda, Jiří Vencovský, Alex Godwood, Marius Albulescu, M. Alex Michaels, Xiang Guo, David Close & Michael Weinblatt. (2018) Mavrilimumab, a Fully Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor α Monoclonal Antibody. Arthritis & Rheumatology 70:5, pages 679-689.
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Ennio Giulio Favalli, Maria Gabriella Raimondo, Andrea Becciolini, Chiara Crotti, Martina Biggioggero & Roberto Caporali. (2017) The management of first-line biologic therapy failures in rheumatoid arthritis: Current practice and future perspectives. Autoimmunity Reviews 16:12, pages 1185-1195.
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