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Clayton H. Rische, Ariel H. Thames, Rebecca A. Krier-Burris, Jeremy A. O’Sullivan, Bruce S. Bochner & Evan A. Scott. (2023) Drug delivery targets and strategies to address mast cell diseases. Expert Opinion on Drug Delivery 20:2, pages 205-222.
Read now
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Christina C Kao & Amit D Parulekar. (2019) Spotlight on fevipiprant and its potential in the treatment of asthma: evidence to date. Journal of Asthma and Allergy 12, pages 1-5.
Read now
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Giancarlo Marone, Maria Rosaria Galdiero, Antonio Pecoraro, Valentina Pucino, Gjada Criscuolo, Maria Triassi & Gilda Varricchi. (2019) Prostaglandin D2 receptor antagonists in allergic disorders: safety, efficacy, and future perspectives. Expert Opinion on Investigational Drugs 28:1, pages 73-84.
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Eric D Bateman, Christopher O’Brien, Paul Rugman, Sally Luke, Stefan Ivanov & Mohib Uddin. (2018) Efficacy and safety of the CRTh2 antagonist AZD1981 as add-on therapy to inhaled corticosteroids and long-acting β2-agonists in patients with atopic asthma. Drug Design, Development and Therapy 12, pages 1093-1106.
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Jiangtao Lin, Xin Zhou, Changzheng Wang, Chuntao Liu, Shaoxi Cai & Mao Huang. (2018) Symbicort® Maintenance and Reliever Therapy (SMART) and the evolution of asthma management within the GINA guidelines. Expert Review of Respiratory Medicine 12:3, pages 191-202.
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Amelia Licari, Riccardo Castagnoli, Ilaria Brambilla, Alessia Marseglia, Maria Angela Tosca, Gian Luigi Marseglia & Giorgio Ciprandi. (2018) New approaches for identifying and testing potential new anti-asthma agents. Expert Opinion on Drug Discovery 13:1, pages 51-63.
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Dave Singh, Arjun Ravi & Thomas Southworth. (2017) CRTH2 antagonists in asthma: current perspectives. Clinical Pharmacology: Advances and Applications 9, pages 165-173.
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Neil C Thomson. (2017) New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma. Expert Opinion on Pharmacotherapy 18:3, pages 283-293.
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Articles from other publishers (44)
Cheng Zeng, Jing Liu, Xialei Zheng, Xinqun Hu & Yuhu He. (2023) Prostaglandin and prostaglandin receptors: present and future promising therapeutic targets for pulmonary arterial hypertension. Respiratory Research 24:1.
Crossref
Crossref
Shan Jing, Wenfang Liu, Kexu Yang, Yang Lin, Xuekun Yao & Guilan Sun. (2022)
The randomized, single‐ and multiple‐ ascending dose studies of the safety, tolerability, pharmacokinetics of
CSPCHA115
in healthy Chinese subjects
. Clinical and Translational Science 16:3, pages 447-458.
Crossref
Crossref
Hugo Farne, Nicholas Glanville, Nicholas Johnson, Tata Kebadze, Julia Aniscenko, Eteri Regis, Jie Zhu, Maria-Belen Trujillo-Torralbo, Onn Min Kon, Patrick Mallia, A Toby Prevost, Michael R Edwards, Sebastian L Johnston, Aran Singanayagam & David J Jackson. (2022) Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial. Thorax 77:10, pages 950-959.
Crossref
Crossref
Romain Mary, Fanny Chalmin, Théo Accogli, Mélanie Bruchard, Christophe Hibos, Joséphine Melin, Caroline Truntzer, Emeric Limagne, Valentin Derangère, Marion Thibaudin, Etienne Humblin, Romain Boidot, Sandy Chevrier, Laurent Arnould, Corentin Richard, Quentin Klopfenstein, Antoine Bernard, Yoshihiro Urade, James A. Harker, Lionel Apetoh, François Ghiringhelli & Frédérique Végran. (2022) Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects. Cancer Immunology Research 10:7, pages 900-916.
Crossref
Crossref
Caroline P. E. Price, Amina Guo, Whitney W. Stevens, Leslie Cousens, Thanh‐Huyen T. Vu, Lydia A. Suh, Kristin A. Erickson, David Conley, Leslie C. Grammer, Robert C. Kern, Bruce K. Tan, Atsushi Kato, Robert P. Schleimer, Stephanie S. Smith, Kevin C. Welch & Anju T. Peters. (2022) Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A randomized controlled clinical trial. Clinical & Experimental Allergy 52:7, pages 859-867.
Crossref
Crossref
Dave Singh. 2022. Encyclopedia of Respiratory Medicine. Encyclopedia of Respiratory Medicine
741
753
.
Ruth Prendecki & Ian M Adcock. 2022. Encyclopedia of Respiratory Medicine. Encyclopedia of Respiratory Medicine
334
341
.
Jorge Maspero, Ioana Octavia Agache, Tadashi Kamei, Makoto Yoshida, Bryan Boone, James M. Felser, Fernando Kawakami, Barbara Knorr, David Lawrence, Thomas Lehmann, Wei Wang & Andrew J. Pedinoff. (2021) Long-term safety and exploratory efficacy of fevipiprant in patients with inadequately controlled asthma: the SPIRIT randomised clinical trial. Respiratory Research 22:1.
Crossref
Crossref
Dorian Hassoun, Olivier Malard, Sébastien Barbarot, Antoine Magnan & Luc Colas. (2021) Type 2 immunity‐driven diseases: Towards a multidisciplinary approach. Clinical & Experimental Allergy 51:12, pages 1538-1552.
Crossref
Crossref
Heng LiuR. N. V. Krishna Deepak, Anna Shiriaeva, Cornelius GatiAlexander Batyuk, Hao HuUwe Weierstall, Wei Liu, Lei Wang, Vadim Cherezov, Hao FanCheng Zhang. (2021)
Molecular basis for lipid recognition by the prostaglandin D
2
receptor CRTH2
. Proceedings of the National Academy of Sciences 118:32.
Crossref
Crossref
Dan Yang, Xinning Guo, Ting Liu, Yina Li, Zhuman Du & Chuntao Liu. (2021) Efficacy and Safety of Prostaglandin D2 Receptor 2 Antagonism with Fevipiprant for Patients with Asthma: a Systematic Review and Meta-analysis of Randomized Controlled Trials. Current Allergy and Asthma Reports 21:7.
Crossref
Crossref
Wei-Jie Li, Yun Zhao, Yuan Gao, Ling-Ling Dong, Yin-Fang Wu, Zhi-Hua Chen & Hua-Hao Shen. (2021) Lipid metabolism in asthma: Immune regulation and potential therapeutic target. Cellular Immunology 364, pages 104341.
Crossref
Crossref
Francesco Nucera, Federica Lo Bello, Sj S. Shen, Paolo Ruggeri, Irene Coppolino, Antonino Di Stefano, Cristiana Stellato, Vincenzo Casolaro, Phil M. Hansbro, Ian M. Adcock & Gaetano Caramori. (2021) Role of Atypical Chemokines and Chemokine Receptors Pathways in the Pathogenesis of COPD. Current Medicinal Chemistry 28:13, pages 2577-2653.
Crossref
Crossref
Kellen J. Cavagnero & Taylor A. Doherty. (2021) Lipid-mediated innate lymphoid cell recruitment and activation in aspirin-exacerbated respiratory disease. Annals of Allergy, Asthma & Immunology 126:2, pages 135-142.
Crossref
Crossref
Shadab Abadpour, Björn Tyrberg, Simen W. Schive, Charlotte Wennberg Huldt, Peter Gennemark, Erik Ryberg, Tina Rydén-Bergsten, David M. Smith, Olle Korsgren, Stanko Skrtic, Hanne Scholz & Maria Sörhede Winzell. (2020) Inhibition of the prostaglandin D2–GPR44/DP2 axis improves human islet survival and function. Diabetologia 63:7, pages 1355-1367.
Crossref
Crossref
Christopher E. Brightling, Guy Brusselle & Pablo Altman. (2019)
The impact of the prostaglandin D
2
receptor 2 and its downstream effects on the pathophysiology of asthma
. Allergy 75:4, pages 761-768.
Crossref
Crossref
Koichiro Asano, Hironori Sagara, Masakazu Ichinose, Masayuki Hirata, Akihiro Nakajima, Hector Ortega & Yuji Tohda. (2020) A Phase 2a Study of DP2 Antagonist GB001 for Asthma. The Journal of Allergy and Clinical Immunology: In Practice 8:4, pages 1275-1283.e1.
Crossref
Crossref
Kijeong Lee, Sang Hag Lee & Tae Hoon Kim. (2020) The Biology of Prostaglandins and Their Role as a Target for Allergic Airway Disease Therapy. International Journal of Molecular Sciences 21:5, pages 1851.
Crossref
Crossref
Abdul Rashid Issahaku, Clement Agoni, Ransford O. Kumi, Fisayo A. Olotu & Mahmoud E. S. Soliman. (2020) Lipid‐Embedded Molecular Dynamics Simulation Model for Exploring the Reverse Prostaglandin D2 Agonism of CT‐133 towards CRTH2 in the Treatment of Type‐2 Inflammation Dependent Diseases. Chemistry & Biodiversity 17:3.
Crossref
Crossref
Keisuke Orimo, Hirohisa Saito, Kenji MatsumotoHideaki Morita. (2020) Innate Lymphoid Cells in the Airways: Their Functions and Regulators. Allergy, Asthma & Immunology Research 12:3, pages 381.
Crossref
Crossref
Stacy Gelhaus Wendell, Hao Fan & Cheng Zhang. (2019) G Protein–Coupled Receptors in Asthma Therapy: Pharmacology and Drug Action. Pharmacological Reviews 72:1, pages 1-49.
Crossref
Crossref
Abdul R. Issahaku, Clement Agoni, Opeyemi S. Soremekun, Patrick A. Kubi, Ransford O. Kumi, Fisayo A. Olotu & Mahmoud E.S. Soliman. (2019) Same Target, Different Therapeutic Outcomes: The Case of CAY10471 and Fevipiprant on CRTh2 Receptor in Treatment of Allergic Rhinitis and Asthma. Combinatorial Chemistry & High Throughput Screening 22:8, pages 521-533.
Crossref
Crossref
Heimo Breiteneder, Zuzana Diamant, Thomas Eiwegger, Wytske J. Fokkens, Claudia Traidl‐Hoffmann, Kari Nadeau, Robyn E. O’Hehir, Liam O’Mahony, Oliver Pfaar, Maria J. Torres, De Yun Wang, Luo Zhang & Cezmi A. Akdis. (2019) Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care. Allergy 74:12, pages 2293-2311.
Crossref
Crossref
Seyyed Shamsadin Athari. (2019) Targeting cell signaling in allergic asthma. Signal Transduction and Targeted Therapy 4:1.
Crossref
Crossref
Zuzana Diamant, Susanne Vijverberg, Kjell Alving, Arzu Bakirtas, Leif Bjermer, Adnan Custovic, Sven‐Erik Dahlen, Mina Gaga, Roy Gerth van Wijk, Stefano Del Giacco, Eckard Hamelmann, Liam G. Heaney, Enrico Heffler, Ömer Kalayci, Konstantinos Kostikas, Rene Lutter, Anna‐Carin Olin, Svetlana Sergejeva, Angela Simpson, Peter J. Sterk, Ellen Tufvesson, Ioana Agache & Sven F. Seys. (2019)
Toward clinically applicable biomarkers for asthma: An
EAACI
position paper
. Allergy 74:10, pages 1835-1851.
Crossref
Crossref
Sofia Helfrich, Barbara C. Mindt, Jörg H. Fritz & Claudia U. Duerr. (2019) Group 2 Innate Lymphoid Cells in Respiratory Allergic Inflammation. Frontiers in Immunology 10.
Crossref
Crossref
Martine Géhin, Dominik Lott, Hervé Farine, Milena Issac, Daniel Strasser, Patricia Sidharta & Jasper Dingemanse. (2019) Pharmacokinetics, pharmacodynamics, tolerability and prediction of clinically effective dose of ACT‐774312: A novel CRTH2 antagonist. Basic & Clinical Pharmacology & Toxicology 124:6, pages 711-721.
Crossref
Crossref
Malcolm R. Starkey, Andrew NJ. McKenzie, Gabrielle T. Belz & Philip M. Hansbro. (2019) Pulmonary group 2 innate lymphoid cells: surprises and challenges. Mucosal Immunology 12:2, pages 299-311.
Crossref
Crossref
R. Stokes PeeblesJr.Jr. & Mark A. Aronica. (2019) Proinflammatory Pathways in the Pathogenesis of Asthma. Clinics in Chest Medicine 40:1, pages 29-50.
Crossref
Crossref
Chengcan Yao & Shuh Narumiya. (2018) Prostaglandin‐cytokine crosstalk in chronic inflammation. British Journal of Pharmacology 176:3, pages 337-354.
Crossref
Crossref
R. Stokes PeeblesJrJr. (2019) Prostaglandins in asthma and allergic diseases. Pharmacology & Therapeutics 193, pages 1-19.
Crossref
Crossref
Stanko Skrtic, Björn Tyrberg, Malin Broberg, Hans Ericsson, Volker Schnecke, Magnus Kjaer, Marcus Hompesch, Eva-Marie Andersson, Erik Ryberg, Alexander Aivazidis, Charlotte Wennberg Huldt, Lars Löfgren, Linda Morrow, Joanna Parkinson, Tina Rydén-Bergsten, Elaine Watkins & Maria Sörhede Winzell. (2018) Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients. PLOS ONE 13:12, pages e0208998.
Crossref
Crossref
Jing Yang, Jian Luo, Ling Yang, Dan Yang, Dan Wang, Bicui Liu, Tingxuan Huang, Xiaohu Wang, Binmiao Liang & Chuntao Liu. (2018) Efficacy and safety of antagonists for chemoattractant receptor-homologous molecule expressed on Th2 cells in adult patients with asthma: a meta-analysis and systematic review. Respiratory Research 19:1.
Crossref
Crossref
Christian Domingo, Oscar Palomares, David A. Sandham, Veit J. Erpenbeck & Pablo Altman. (2018) The prostaglandin D2 receptor 2 pathway in asthma: a key player in airway inflammation. Respiratory Research 19:1.
Crossref
Crossref
Lei Wang, Dandan Yao, R.N.V. Krishna Deepak, Heng Liu, Qingpin Xiao, Hao Fan, Weimin Gong, Zhiyi Wei & Cheng Zhang. (2018) Structures of the Human PGD2 Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition. Molecular Cell 72:1, pages 48-59.e4.
Crossref
Crossref
Michael D. Howell, Carolyn Fitzsimons & Paul A. Smith. (2018) JAK/STAT inhibitors and other small molecule cytokine antagonists for the treatment of allergic disease. Annals of Allergy, Asthma & Immunology 120:4, pages 367-375.
Crossref
Crossref
Jennifer A. Walker & Andrew N. J. McKenzie. (2017) TH2 cell development and function. Nature Reviews Immunology 18:2, pages 121-133.
Crossref
Crossref
Fulvio Braido, Ilaria Baiardini & Giorgio W. Canonica. (2018) Patient-reported outcomes in asthma clinical trials. Current Opinion in Pulmonary Medicine 24:1, pages 70-77.
Crossref
Crossref
Eileen Wang, Nicole Barberis & Rohit K. Katial. 2018. Personalizing Asthma Management for the Clinician. Personalizing Asthma Management for the Clinician
19
32
.
Christoph Wilhelm, Schekufe Kharabi Masouleh & Alexander Kazakov. (2017) Metabolic Regulation of Innate Lymphoid Cell-Mediated Tissue Protection—Linking the Nutritional State to Barrier Immunity. Frontiers in Immunology 8.
Crossref
Crossref
Alok K. Verma, Murli Manohar, Sathisha Upparahalli Venkateshaiah & Anil Mishra. (2017) Neuroendocrine cells derived chemokine vasoactive intestinal polypeptide (VIP) in allergic diseases. Cytokine & Growth Factor Reviews 38, pages 37-48.
Crossref
Crossref
Katharina Jandl & Akos Heinemann. (2017) The therapeutic potential of CRTH2/DP2 beyond allergy and asthma. Prostaglandins & Other Lipid Mediators 133, pages 42-48.
Crossref
Crossref
Maciej Kupczyk & Piotr Kuna. (2017) Targeting the PGD2/CRTH2/DP1 Signaling Pathway in Asthma and Allergic Disease: Current Status and Future Perspectives. Drugs 77:12, pages 1281-1294.
Crossref
Crossref
Aldara Martin Alonso & Sejal Saglani. (2017) Mechanisms Mediating Pediatric Severe Asthma and Potential Novel Therapies. Frontiers in Pediatrics 5.
Crossref
Crossref