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Original Research

Efficacy and safety of two fixed-dose combinations of S-amlodipine and telmisartan (CKD-828) versus S-amlodipine monotherapy in patients with hypertension inadequately controlled using S-amlodipine monotherapy: an 8-week, multicenter, randomized, double-blind, Phase III clinical study

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Pages 3817-3826 | Published online: 23 Nov 2016

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Woo Youl Kang, Sook Jin Seong, Boram Ohk, Mi-Ri Gwon, Bo Kyung Kim, Sookie La, Hyun-Ju Kim, Seungil Cho, Young-Ran Yoon, Dong Heon Yang & Hae Won Lee. (2018) Pharmacokinetic and bioequivalence study of a telmisartan/S-amlodipine fixed-dose combination (CKD-828) formulation and coadministered telmisartan and S-amlodipine in healthy subjects. Drug Design, Development and Therapy 12, pages 545-553.
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Mengxin Xie, Tianjiao Tang & Hongsheng Liang. (2023) Efficacy of single‐pill combination in uncontrolled essential hypertension: A systematic review and network meta‐analysis. Clinical Cardiology 46:8, pages 886-898.
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Bong-Joon Kim, Kyoung-Im Cho, Hyuck Moon Kwon, Seung-Min Choi, Chang-Hwan Yoon, Sang Wook Lim, Seung-Jae Joo, Nam Ho Lee, Sang-Yup Lim, Seong-Hoon Lim & Hyo-Soo Kim. (2022) Effect of a fixed-dose combination of Telmisartan/S-amlodipine on circadian blood pressure compared with Telmisartan monotherapy: TENUVA-BP study. Clinical Hypertension 28:1.
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Sang-Ho Jo, Sung-Ji Park, Geu-Ru Hong, Sang Wook Kim & Chang-Gyu Park. (2020) Telmisartan Plus S-Amlodipine Single-Pill Combination Therapy is Safe and Effective in Patients with Hypertension from Large-Scale Nationwide Surveillance Data in Korea (NOVEL) Study. Advances in Therapy 38:1, pages 304-315.
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Dae Wook Lee, Mira Jung, Hye Won Wang, Zainah Khan & Philippe Pinton. (2019) Systematic Review with Network Meta-Analysis: Comparative Efficacy and Safety of Combination Therapy with Angiotensin II Receptor Blockers and Amlodipine in Asian Hypertensive Patients. International Journal of Hypertension 2019, pages 1-8.
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Honami Kojima, Saki Nakamura, Tamami Haraguchi, Miyako Yoshida, Masaaki Habara, Hidekazu Ikezaki & Takahiro Uchida. (2019) A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan. Journal of Pharmacy and Pharmacology 71:9, pages 1384-1392.
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Jamshed Dalal, J. C. Mohan, S. S. Iyengar, Jagdish Hiremath, Immaneni Sathyamurthy, Sandeep Bansal, Dhiman Kahali & Arup Dasbiswas. (2018) S-Amlodipine: An Isomer with Difference—Time to Shift from Racemic Amlodipine. International Journal of Hypertension 2018, pages 1-14.
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