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Drug Design, Development and Therapy Volume 10, 2016 - Issue
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Original Research

The aqueous extract of Brucea javanica suppresses cell growth and alleviates tumorigenesis of human lung cancer cells by targeting mutated epidermal growth factor receptor

Seung-Hun Kim1 Department of Life Science, National Taiwan Normal University, Taipei
,
Chun-Yen Liu1 Department of Life Science, National Taiwan Normal University, Taipei
,
Po-Wei Fan1 Department of Life Science, National Taiwan Normal University, Taipei
,
Chang-Heng Hsieh1 Department of Life Science, National Taiwan Normal University, Taipei
,
Hsuan-Yuan Lin1 Department of Life Science, National Taiwan Normal University, Taipei
,
Ming-Chung Lee2 Brion Research Institute of Taiwan, New Taipei City, Taiwan
&
Kang Fang1 Department of Life Science, National Taiwan Normal University, TaipeiCorrespondence[email protected]
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Pages 3599-3609 | Published online: 03 Nov 2016

Citations (16)

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Hyun-Ji Park & Shin-Hyung Park. (2023) The Ethanolic Extract of Trichosanthes Kirilowii Root Exerts anti-Cancer Effects in Human Non-Small Cell Lung Cancer Cells Resistant to EGFR TKI. Nutrition and Cancer 75:1, pages 376-387.
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Elham Bagheri, Fatemeh Hajiaghaalipour, Shaik Nyamathulla & Nur’Ain Salehen. (2018) The apoptotic effects of Brucea javanica fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-κB translocation. Drug Design, Development and Therapy 12, pages 657-671.
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Articles from other publishers (14)

Haohao Guo, Yuan Chen, Jing Wang, Huizhong Ma & Yufeng Liu. (2022) A critical review: anti-cancer effects of Brucea javanica and the mechanisms. Pharmacological Research - Modern Chinese Medicine 4, pages 100133.
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Norzila Ismail, Aida Maziha Zainudin & Gan Siew Hua. (2021) Normalisation of human chorionic gonadotrophin (hCG) levels in a patient with partial molar pregnancy with a uterine mass without chemotherapy: impact of using herbal remedies. Journal of Complementary and Integrative Medicine 18:4, pages 859-863.
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Chang-liang Yao, Jian-qing Zhang, Jia-yuan Li, Wen-long Wei, Shi-fei Wu & De-an Guo. (2021) Traditional Chinese medicine (TCM) as a source of new anticancer drugs. Natural Product Reports 38:9, pages 1618-1633.
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Hiu Lee, Mingjing Meng, Yulong Liu, Tao Su & Hiu Kwan. (2021) Medicinal herbs and bioactive compounds overcome the drug resistance to epidermal growth factor receptor inhibitors in non‑small cell lung cancer (Review). Oncology Letters 22:3.
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Y. Huang, L. Chen, B. He, S.Y. Liu, D.Q. Zeng, Y.H. Wang, L.W. Du & W.W. Tang. (2021) Herbicidal activity and bioactive components of Brucea javanica (L.) Merr. residue. Arabian Journal of Chemistry 14:7, pages 103228.
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Kun-wei Li, Yi-yu Liang, Qi Wang, Ying Li, Sheng-jun Zhou, Hao-cheng Wei, Chang-zheng Zhou & Xin-huan Wan. (2021) Brucea javanica: A review on anticancer of its pharmacological properties and clinical researches. Phytomedicine 86, pages 153560.
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Gizem CEYLAN & Sabahattin CÖMERTPAY. (2020) Kapsaisinin H2452 Mezotelyoma Hücre Hattından Seçilen Klon larda Sitotoksisitesinin ve Kaspaz-3 Üzerine Etkilerinin BelirlenmesiDetermination of the Cytotoxicity of Capsaicin and its Effects on Caspase-3 in the Clones Selected from H2452 Mesothelioma Cell Line. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 23:5, pages 1125-1134.
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Yung-Sheng Lin, Wen-Ying Huang, Pang-Yen Ho, Shiou-Yih Hu, Ying-Yi Lin, Cheng-You Chen, Min-Yun Chang & Shu-Ling Huang. (2020) Effects of Storage Time and Temperature on Antioxidants in Juice from Momordica charantia L. and Momordica charantia L. var. abbreviata Ser.. Molecules 25:16, pages 3614.
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Edy Meiyanto & Yonika Arum Larasati. (2019) The Chemopreventive Activity of Indonesia Medicinal Plants Targeting on Hallmarks of Cancer. Advanced Pharmaceutical Bulletin 9:2, pages 219-230.
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Ravini Ayoddhia Sirilal Gurunanselage Don & Michelle Khai Khun Yap. (2019) Arctium lappa L. root extract induces cell death via mitochondrial-mediated caspase-dependent apoptosis in Jurkat human leukemic T cells. Biomedicine & Pharmacotherapy 110, pages 918-929.
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Seul Ah Lee, Bo-Ram Park, Sung Min Moon, Do Kyung Kim & Chun Sung Kim. (2018) Methanol Extracts of <i>Codium fragile</i> Induces Apoptosis through G1/S Cell Cycle Arrest in FaDu Human Hypopharynx Squamous Carcinoma Cells. International Journal of Oral Biology 43:2, pages 61-68.
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E. Bagheri, F. Hajiaghaalipour, S. Nyamathulla & N. A. Salehen. (2018) Ethanolic extract of Brucea javanica inhibit proliferation of HCT-116 colon cancer cells via caspase activation . RSC Advances 8:2, pages 681-689.
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Chao-Min Wang, Shang-Jie Tsai, Yun-Lian Jhan, Kuei-Lin Yeh & Chang-Hung Chou. (2017) Anti-Proliferative Activity of Triterpenoids and Sterols Isolated from Alstonia scholaris against Non-Small-Cell Lung Carcinoma Cells. Molecules 22:12, pages 2119.
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Yu-Ling Ni, Chang-Hung Hsieh, Seung-Hun Kim, Jing-Ping Wang, Chun-Li Su, Ching-Fa Yao & Kang Fang. (2017) A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres. Apoptosis 22:10, pages 1235-1245.
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