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Drug Design, Development and Therapy Volume 12, 2018 - Issue
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Original Research

Formononetin induces vasorelaxation in rat thoracic aorta via regulation of the PI3K/PTEN/Akt signaling pathway

Teng LiLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]
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Yuanyuan ZhongLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]
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Tao TangLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]
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Jiekun LuoLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]
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Hanjin CuiLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]
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Rong FanLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]
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Yang WangLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]Correspondence[email protected] [email protected]
&
Dongsheng WangLaboratory of Ethnopharmacology, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha 410008, China, [email protected]; [email protected]Correspondence[email protected] [email protected]
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Pages 3675-3684 | Published online: 01 Nov 2018

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Haiping Fu, Mingdong Li, Yanqiang Huan, Xiaolei Wang, Mingkai Tao, Tianqi Jiang, Hongbin Xie, Wujisiguleng, Gegentana & Yongxiong He. (2023) Formononetin Inhibits Microglial Inflammatory Response and Contributes to Spinal Cord Injury Repair by Targeting the EGFR/MAPK Pathway. Immunological Investigations 52:4, pages 399-414.
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Articles from other publishers (15)

Xiangren Kong, Chao Liu, Zuzhen Zhang, Meiqi Cheng, Zhijun Mei, Xiangdong Li, Peng Liu, Lihong Diao, Yajie Ma, Peng Jiang, Xiangya Kong, Shiyan Nie, Yingzi Guo, Ze Wang, Xinlei Zhang, Yan Wang, Liujun Tang, Shuzhen Guo, Zhongyang Liu & Dong Li. (2024) BATMAN-TCM 2.0: an enhanced integrative database for known and predicted interactions between traditional Chinese medicine ingredients and target proteins. Nucleic Acids Research 52:D1, pages D1110-D1120.
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Yimeng Li, Jingfang Wu, Huiqian Yu, Xiaoling Lu & Yusu Ni. (2024) Formononetin ameliorates cisplatin-induced hair cell death via activation of the PI3K/AKT-Nrf2 signaling pathway. Heliyon 10:1, pages e23750.
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Zhongqi Shen, Meng Yu & Zhenfei Dong. (2023) Research Progress on the Pharmacodynamic Mechanisms of Sini Powder against Depression from the Perspective of the Central Nervous System. Medicina 59:4, pages 741.
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Haoliang Li, Renhao Jiang, Lejing Lou, Chao Jia, Linfang Zou & Mochuan Chen. (2022) Formononetin Improves the Survival of Random Skin Flaps Through PI3K/Akt-Mediated Nrf2 Antioxidant Defense System. Frontiers in Pharmacology 13.
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A. M. Bogoutdinova, A. K. Whaley, A. O. Ponkratova, A. A. Orlova, M. Yu. Goncharov, V. S. Shpakova, N. T. Farmanova, D. Kh. Nurullaeva, A. T. Sharipov, S. P. Gambaryan & M. N. Povydysh. (2021) Isolation of formononetin-7-O-β-D-glucopyranoside from the grass of Ononis arvensis L. and the assessment of its effect on induced platelet activation. Drug development & registration 10:4, pages 14-19.
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Wei-Kang Luo, Dan Zhou, Jia-Miao Liu, Yang Hang, Zhao-Yu Yang, Yao Wu, Liang-Lin Zhang & Yang Wang. (2021) A Novel Research Technology to Explore the Mystery of Traditional Chinese Medicine: Optogenetics. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-12.
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Fei Tang, Hong-Ling Yan, Li-Xia Wang, Jin-Feng Xu, Cheng Peng, Hui Ao & Yu-Zhu Tan. (2021) Review of Natural Resources With Vasodilation: Traditional Medicinal Plants, Natural Products, and Their Mechanism and Clinical Efficacy. Frontiers in Pharmacology 12.
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Hangfang Lou & Xiaochen Bi. (2021) The Biological Effects of Forkhead Box Protein A2 (FOXA2) on Cervical Cancer Cells by Regulating Phosphatase and Tensin Homolog (PTEN). Journal of Biomaterials and Tissue Engineering 11:4, pages 671-678.
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Jun Chen, Ruilan Du, Chunyan Huang, Lihong Jia, Defu Tie, Zhaohui Fan, Chuting Zhou, Qizhu Chen & Huaben Bo. (2021) Gut microbiota affects the efficacy of Danggui Buxue Tang by affecting plasma concentration of active ingredients. Journal of Ethnopharmacology 270, pages 113835.
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Lingyu Liu, Rong Hu, Haiyan You, Jingjing Li, Yangyang Liu, Qiang Li, Xiaohui Wu, Jiawen Huang, Xiangsheng Cai, Mingqing Wang & Lianbo Wei. (2021) Formononetin ameliorates muscle atrophy by regulating myostatin‐mediated PI3K/Akt/FoxO3a pathway and satellite cell function in chronic kidney disease. Journal of Cellular and Molecular Medicine 25:3, pages 1493-1506.
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Henrique Silva. (2021) The Vascular Effects of Isolated Isoflavones—A Focus on the Determinants of Blood Pressure Regulation. Biology 10:1, pages 49.
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Swati Chaturvedi, Nazneen Sultana, Mamunur Rashid, Zaiba Naseem, Sandeep Kumar Singh & M. Wahajuddin. 2021. Medicinal and Aromatic Plants. Medicinal and Aromatic Plants 325 351 .
Peihua Liu, Longxiang Wu, Harripersaud Chand, Chao Li, Xiheng Hu & Yangle Li. (2020) Silencing of miR-152 contributes to DNMT1-mediated CpG methylation of the PTEN promoter in bladder cancer. Life Sciences 261, pages 118311.
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Guode Li, Qingbo Xu, Kedong Han, Wenhe Yan & Chaopei Huang. (2020) Experimental evidence and network pharmacology-based analysis reveal the molecular mechanism of Tongxinluo capsule administered in coronary heart diseases. Bioscience Reports 40:10.
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Dan-Shu Wang, Liu-Yan Yan, De-Zhi Yang, Yang Lyu, Lian-Hua Fang, Shou-Bao Wang & Guan-Hua Du. (2020) Formononetin ameliorates myocardial ischemia/reperfusion injury in rats by suppressing the ROS-TXNIP-NLRP3 pathway. Biochemical and Biophysical Research Communications 525:3, pages 759-766.
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