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Drug Design, Development and Therapy Volume 14, 2020 - Issue
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Original Research

Soluplus-Mediated Diosgenin Amorphous Solid Dispersion with High Solubility and High Stability: Development, Characterization and Oral Bioavailability

Pei Liu1 Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China;2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of China
,
Jian-yu Zhou2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of China
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Jin-hua Chang2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of China
,
Xi-gang Liu2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of China
,
He-fei Xue2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of China
,
Ru-xing Wang2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of China
,
Zhong-si Li2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of China
,
Chun-shi Li3 Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-4007-9951
ORCID Icon,
Jian Wang3 Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9589-4056
ORCID Icon &
Cui-zhe Liu1 Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China;2 Hebei Province Key Laboratory of Research and Development for Chinese Medicine, Chengde Medical University, Chengde, Hebei 067000, People’s Republic of ChinaCorrespondence[email protected]
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Pages 2959-2975 | Published online: 27 Jul 2020

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S. Parveen, M. Mohamed Subarkhan, G. Kalaiarasi, A. Manikandan, M. Hashem, Hassan Fouad & A. Ansari. (2024) Synthesis, spectral characterization and biological evaluation of diosgenin coordinated ruthenium-arene complexes. Journal of Coordination Chemistry 77:3-4, pages 360-374.
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Sumit Kumar Saha, Amita Joshi, Romi Singh & Kiran Dubey. (2023) Review of industrially recognized polymers and manufacturing processes for amorphous solid dispersion based formulations. Pharmaceutical Development and Technology 28:7, pages 678-696.
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Fengcui Sun, Xiufen Yang, Chaoqun Ma, Shizhao Zhang, Lu Yu, Haifei Lu, Guoliang Yin, Pengpeng Liang, Yanan Feng & Fengxia Zhang. (2021) The Effects of Diosgenin on Hypolipidemia and Its Underlying Mechanism: A Review. Diabetes, Metabolic Syndrome and Obesity 14, pages 4015-4030.
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Junwei Liu, Meihong Zhang, Chuanbin Wu, Xin Pan & Zhengwei Huang. TPGS/soluplus® blended micelles: an effective strategy for improving loading capacity of ferroptosis inducer erastin. Journal of Dispersion Science and Technology 0:0, pages 1-13.
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