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Review

Osteoporosis – a current view of pharmacological prevention and treatment

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Pages 435-448 | Published online: 31 May 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Yuling Xing, Jing Liu, Huanxin Liu & Huijuan Ma. (2022) Relationship of Bone Turnover Markers with Serum Uric Acid-to-Creatinine Ratio in Men and Postmenopausal Women with Type 2 Diabetes. Diabetes, Metabolic Syndrome and Obesity 15, pages 3205-3217.
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Qiang Wang, Yiming Miao, Zhiyuan Qian, Lidong Chen, Tong Lu, Yue Xu, Xiaowei Jiang & Yingchao Shen. (2021) MicroRNA-15a-5p plays a role in osteogenic MC3T3-E1 cells differentiation by targeting PDCD4 (programmed cell death 4) via Wnt/β-catenin dependent signaling pathway. Bioengineered 12:1, pages 8173-8185.
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Noriaki Nagai, Fumihiko Ogata, Hiroko Otake, Yosuke Nakazawa & Naohito Kawasaki. (2018) Design of a transdermal formulation containing raloxifene nanoparticles for osteoporosis treatment. International Journal of Nanomedicine 13, pages 5215-5229.
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Aska Toda, Kenjiro Sawada, Akihiko Yoshimura, Erika Nakatsuka, Hiromasa Kuroda, Katsumi Kozasa, Mayuko Miyamoto, Kae Hashimoto, Seiji Mabuchi & Tadashi Kimura. (2017) Effects of minodronate in postmenopausal women with osteoporosis who received prior treatment with raloxifene. International Journal of Women's Health 9, pages 821-825.
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Deniz Sezlev Bilecen, Jose Carlos Rodriguez-Cabello, Hasan Uludag & Vasif Hasirci. (2017) Construction of a PLGA based, targeted siRNA delivery system for treatment of osteoporosis. Journal of Biomaterials Science, Polymer Edition 28:16, pages 1859-1873.
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Suguru Ito, Akihiro Ohmi, Akiyo Sakamiya, Takeo Yano, Katsuzumi Okumura, Norihiro Nishimura & Kazuhiro Kagontani. (2016) Ginger hexane extract suppresses RANKL-induced osteoclast differentiation. Bioscience, Biotechnology, and Biochemistry 80:4, pages 779-785.
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Articles from other publishers (35)

Zhi-Hui He, Chun-Lan Xie, Taizong Wu, Yu-Ting Yue, Chao-Feng Wang, Lin Xu, Ming-Min Xie, Yong Zhang, You-Jia Hao, Ren Xu & Xian-Wen Yang. (2022) Tetracyclic Steroids Bearing a Bicyclo[4.4.1] Ring System as Potent Antiosteoporosis Agents from the Deep-Sea-Derived Fungus Rhizopus sp. W23 . Journal of Natural Products 86:1, pages 157-165.
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Jian-Hua Li, Ying-Hui Gao, Xin Xue, Xiao-Feng Su, Huan-Huan Wang, Jun-Ling Lin, Li-Bo Zhao, Xiao Zou, Yan Gao, Jing-Jing Guo, Min Shi, Wei-Hao Xu, Ya-Bin Wang, Xiao-Shun Qian, Kai-Bing Chen, Li Fan & Lin Liu. (2022) Association between Serum Cystatin C levels and long‐term cardiovascular outcomes and all-cause mortality in older patients with obstructive sleep apnea. Frontiers in Physiology 13.
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Bayram SÜZER, Nilay SEYİDOĞLU, Kenan TÜFEKÇİ, Deniz KARAKCI & Buket BAKIR. (2022) A Preventive herb against bone loss in diabetic rats: Zingiber officinale. Journal of Istanbul Veterinary Sciences 6:2, pages 76-83.
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Roberta Giordo, Zena Wehbe, Anna Maria Posadino, Gian Luca Erre, Ali H. Eid, Arduino A. Mangoni & Gianfranco Pintus. (2022) Disease-Associated Regulation of Non-Coding RNAs by Resveratrol: Molecular Insights and Therapeutic Applications. Frontiers in Cell and Developmental Biology 10.
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Eirini K. Kydonaki, Laura Freitas, Henrique Reguengo, Carlos Raposo Simón, Ana R. Bastos, Emanuel M. Fernandes, Raphaël F. Canadas, Joaquim M. Oliveira, Vitor M. Correlo, Rui L. Reis, Maria Vliora, Paraskevi Gkiata, Yiannis Koutedakis, Georgia Ntina, Rui Pinto, Andres E. Carrillo, Franklim Marques & Tânia Amorim. (2022) Pharmacological and Non-Pharmacological Agents versus Bovine Colostrum Supplementation for the Management of Bone Health Using an Osteoporosis-Induced Rat Model. Nutrients 14:14, pages 2837.
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Yan Wang, Xiaoqi Zhou & Dalin Wang. (2021) Mesenchymal Stem Cell–Derived Extracellular Vesicles Inhibit Osteoporosis via MicroRNA-27a-Induced Inhibition of DKK2-Mediated Wnt/β-Catenin Pathway. Inflammation 45:2, pages 780-799.
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Yujie Liu, Qinwen Liu, Chuanhui Yin, Yi Li, Jie Wu, Quanlin Chen, Hailang Yu, Aiping Lu & Daogang Guan. (2022) Uncovering Hidden Mechanisms of Different Prescriptions Treatment for Osteoporosis via Novel Bioinformatics Model and Experiment Validation. Frontiers in Cell and Developmental Biology 10.
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ANTONESCU Oana-Raluca, Andrei Emanuel SILIȘTEANU, Mihaela RACHERIU & Cosmin MIHALACHE. (2021) Assessment of the importance of physical activity and quality of life for patients diagnosed with osteoporosis during the COVID-19 pandemic. Balneo and PRM Research Journal:Vol.12, no.4, pages 386-391.
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O. N. Tkacheva, A. V. Naumov, Yu. V. Kotovskaya, N. K. Runikhina, A. S. Mil'toL. A. Alexanyan, N. O. Khovasova, V. I. Moroz, T. M. Manevich, A. V. Rozanov, V. S. Ostapenko & A. D. Meshkov. (2021) Chronic pain in older and senile patients. Clinical guidelines. Russian Journal of Geriatric Medicine:3, pages 275-320.
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I. V. Kuznetsova & R. A. Chilova. (2021) Menopausal osteoporosis in the practice of a gynecologist. Meditsinskiy sovet = Medical Council:12, pages 320-331.
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Seon Yu Kim, Hee-Ju Lee, Taehyun Kim, Yeong-Geun Lee, Jeong Eun Kwon & Se Chan Kang. (2021) Anti-Osteoporotic Activity of Pueraria lobata Fermented with Lactobacillus paracasei JS1 by Regulation of Osteoblast Differentiation and Protection against Bone Loss in Ovariectomized Mice. Fermentation 7:3, pages 186.
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Eirini K. Kydonaki, Laura Freitas, Bruno M. Fonseca, Henrique Reguengo, Carlos Raposo Simón, Ana R. Bastos, Emanuel M. Fernandes, Raphaël F. Canadas, Joaquim Miguel Oliveira, Vitor M. Correlo, Rui L. Reis, Maria Vliora, Parakevi Gkiata, Yiannis Koutedakis, Georgia Ntina, Rui Pinto, Andres E. Carrillo, Franklim Marques & Tânia Amorim. (2021) Bovine Colostrum Supplementation Improves Bone Metabolism in an Osteoporosis-Induced Animal Model. Nutrients 13:9, pages 2981.
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Jéssica S. Barbosa, Miguel Pinto, Sandra Barreiro, Carlos Fernandes, Ricardo F. Mendes, Pedro Lavrador, Vítor M. Gaspar, João F. Mano, Fernanda Borges, Fernando Remião, Susana S. Braga & Filipe A. Almeida Paz. (2021) Coordination Compounds As Multi-Delivery Systems for Osteoporosis. ACS Applied Materials & Interfaces 13:30, pages 35469-35483.
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Ayotunde Oladunni Ale, Oluwayomi Akande & David Da Rocha-Afodu. 2021. Mineral Deficiencies - Electrolyte Disturbances, Genes, Diet and Disease Interface. Mineral Deficiencies - Electrolyte Disturbances, Genes, Diet and Disease Interface.
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Ioannis PapadakisAlexandra SpanouDemos Kalyvas. (2021) Success Rate and Safety of Dental Implantology in Patients Treated With Antiresorptive Medication: A Systematic Review. Journal of Oral Implantology 47:2, pages 169-180.
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Bingkun Zhao, Qian Peng, Enoch Hin Lok Poon, Fubo Chen, Rong Zhou, Guangwei Shang, Dan Wang, Yuanzhi Xu, Raorao Wang & Shengcai Qi. (2021) Leonurine Promotes the Osteoblast Differentiation of Rat BMSCs by Activation of Autophagy via the PI3K/Akt/mTOR Pathway. Frontiers in Bioengineering and Biotechnology 9.
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Vagelis Rinotas, Athanasios Papakyriakou, Foteini Violitzi, Christos Papaneophytou, Maria-Dimitra Ouzouni, Polyxeni Alexiou, Alexandros Strongilos, Elias Couladouros, George Kontopidis, Elias Eliopoulos & Eleni Douni. (2020) Discovery of Small-Molecule Inhibitors of Receptor Activator of Nuclear Factor-κB Ligand with a Superior Therapeutic Index. Journal of Medicinal Chemistry 63:20, pages 12043-12059.
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Tomikazu Kawano, Aoi Sugawara, Toshika Ohashi, Satoshi Ogawa, Naomi Matsumoto, Mayumi Nakanishi-Matsui & Satoru Tamura. (2020) Synthesis and Biological Evaluation of New Curcumin Analogs Inhibiting Osteoclastogenesis. HETEROCYCLES 100:8, pages 1233.
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Vasilis Paspaliaris & George Kolios. (2019) Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches. Stem Cells International 2019, pages 1-16.
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F. Yang, Z. W. Lin, T. Y. Huang, T. T. Chen, J. Cui, M. Y. Li & Y. Q. Hua. (2019) Ligustilide, a major bioactive component of Angelica sinensis, promotes bone formation via the GPR30/EGFR pathway. Scientific Reports 9:1.
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Jiantao Hu, Biao Hu, Mingliang Wang, Fuming Xu, Bukeyan Miao, Chao-Yie Yang, Mi Wang, Zhaomin Liu, Daniel F. Hayes, Krishnapriya Chinnaswamy, James Delproposto, Jeanne Stuckey & Shaomeng Wang. (2019) Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER). Journal of Medicinal Chemistry 62:3, pages 1420-1442.
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Jiao Mo, Renhua Yang, Fan Li, Bo He, Xiaochao Zhang, Yuqin Zhao, Zhiqiang Shen & Peng Chen. (2018) Geraniin promotes osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) via activating β-catenin: a comparative study between BMSCs from normal and osteoporotic rats. Journal of Natural Medicines 73:1, pages 262-272.
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Tsz Ho Chow, Bo Yee Lee, Adrian Bing Fung Ang, Veronica Yi Ki Cheung, Michelle Man Ching Ho & Saori Takemura. (2018) The effect of Chinese martial arts Tai Chi Chuan on prevention of osteoporosis: A systematic review. Journal of Orthopaedic Translation 12, pages 74-84.
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Sachin R. Chaugule, Madhavi M. Indap & Shubhada V. Chiplunkar. (2017) Marine Natural Products: New Avenue in Treatment of Osteoporosis. Frontiers in Marine Science 4.
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Vito Pavone, Gianluca Testa, Serena M. C. Giardina, Andrea Vescio, Domenico A. Restivo & Giuseppe Sessa. (2017) Pharmacological Therapy of Osteoporosis: A Systematic Current Review of Literature. Frontiers in Pharmacology 8.
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A. Modi, S. Sajjan, R. Insinga, J. Weaver, E. M. Lewiecki & S. T. Harris. (2017) Frequency of discontinuation of injectable osteoporosis therapies in US patients over 2 years. Osteoporosis International 28:4, pages 1355-1363.
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Qiaozhen Zhou, Li Zhu, Dafeng Zhang, Ning Li, Qiao Li, Panpan Dai, Yixin Mao, Xumin Li, Jianfeng Ma & Shengbin Huang. (2016) Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses. Disease Markers 2016, pages 1-12.
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Stephen SwiokloKimberly A. WatsonElizabeth M. WilliamsonJonathan A. FarrimondSophie E. PutnamKatrina A. Bicknell. (2015) Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids. Journal of Natural Products 78:11, pages 2598-2608.
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Ki-Jong Kim, Hyun-Ju Jun, Han-Shin Jeong, Dae-Jung Jeon & Sung-Ha Ji. (2015) The relationship between fracture and quality of life in Korean adults receiving treatment for osteoporosis based on the 2010 Korean Community Health Survey. Journal of Physical Therapy Science 27:7, pages 2083-2086.
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Susumu Ikehara & Ming Li. (2014) Stem cell transplantation improves aging-related diseases. Frontiers in Cell and Developmental Biology 2.
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