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Drug Design, Development and Therapy Volume 15, 2021 - Issue
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Original Research

Qilin Pill Exerts Therapeutic Effect on Resection-Induced Premature Ovarian Insufficiency Rats by Inhibiting the MAPK and PI3K-AKT Signaling Pathways

Debao Li1 School of Pharmacy, Fudan University, Shanghai, 201203, People’s Republic of China;2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China
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Yuling Jia2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China
,
Yiwen Hou2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China
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Dingshi Chen2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China
,
Chiyang Zheng2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China
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Lifen Chen2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China
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Li Zhou2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Zuyue Sun2 National Health Commission (NHC) Key Laboratory of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200032, People’s Republic of China;3 Reproductive and Developmental Research Institute of Fudan University, Shanghai, 200032, People’s Republic of China
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Pages 3331-3345 | Published online: 30 Jul 2021

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Ying Cao, Yue Chen, Peijuan Wang, Jialin Lu, Xuan Han & Jingyao She. (2021) Network pharmacology and experimental validation to explore the molecular mechanisms of Bushen Huoxue for the treatment of premature ovarian insufficiency. Bioengineered 12:2, pages 10345-10362.
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Articles from other publishers (5)

Feng-Xia Liu & Yan Sun. (2023) Identification of the active ingredients and pharmacological effects of Kuntai capsules in the treatment of primary ovarian insufficiency: A review. Medicine 102:21, pages e33884.
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Qiao-li Zhang, Ya-ling Lei, Yan Deng, Rui-lin Ma, Xue-song Ding, Wei Xue & Ai-jun Sun. (2022) Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine. Chinese Journal of Integrative Medicine 29:4, pages 361-367.
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Xiaoshuang Zhao, Zengfang Yu, Dan Li & Junguo Duan. (2022) Using Network Pharmacology and Molecular Docking to Explore the Mechanism of Qiju Dihuang Pill against Dry Eye Disease. Computational and Mathematical Methods in Medicine 2022, pages 1-13.
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Fengying Hu, Xianwei Zhou, Yanjiao Jiang, Xinhe Huang, Shaoqin Sheng & Dongsheng Li. (2022) Effect of Myrcene on Th17/Treg Balance and Endocrine Function in Autoimmune Premature Ovarian Insufficiency Mice through the MAPK Signaling Pathway. Protein & Peptide Letters 29:11, pages 954-961.
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Ming Kang Qi, Tie Cheng Sun, Li Ya Yang, Jia Lin He, Yi Ming Guo, Han Bi Wang & Hui Ping Wang. (2022) Therapeutic Effect of Melatonin in Premature Ovarian Insufficiency: Hippo Pathway Is Involved. Oxidative Medicine and Cellular Longevity 2022, pages 1-15.
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