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Case Series

Treating refractory dermatomyositis or polymyositis with adrenocorticotropic hormone gel: a retrospective case series

Pages 133-139 | Published online: 11 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Rachel Zeng, Stefanie Glaubitz & Jens Schmidt. (2021) Inflammatory myopathies: shedding light on promising agents and combination therapies in clinical trials. Expert Opinion on Investigational Drugs 30:11, pages 1125-1140.
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Nancy Ho-Mahler, Beni Turner, Michael Eaddy, Mark L Hanke & Winnie W Nelson. (2020) Treatment with Repository Corticotropin Injection in Patients with Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Dermatomyositis/Polymyositis. Open Access Rheumatology: Research and Reviews 12, pages 21-28.
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Tanya Chandra & Rohit Aggarwal. (2020) Clinical trials and novel therapeutics in dermatomyositis. Expert Opinion on Emerging Drugs 25:3, pages 213-228.
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Hirokazu Sasaki & Hitoshi Kohsaka. (2018) Current diagnosis and treatment of polymyositis and dermatomyositis. Modern Rheumatology 28:6, pages 913-921.
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Verena Isak & Joseph L. Jorizzo. (2018) Recent developments on treatment strategies and the prognosis of dermatomyositis: a review. Journal of Dermatological Treatment 29:5, pages 450-459.
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Tyler Knight, T Christopher Bond, Breanna Popelar, Li Wang, John W Niewoehner, Kathryn Anastassopoulos & Michael Philbin. (2017) Medical resource utilization in dermatomyositis/polymyositis patients treated with repository corticotropin injection, intravenous immunoglobulin, and/or rituximab. ClinicoEconomics and Outcomes Research 9, pages 271-279.
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Siamak Moghadam-Kia, Rohit Aggarwal & Chester V Oddis. (2015) Treatment of inflammatory myopathy: emerging therapies and therapeutic targets. Expert Review of Clinical Immunology 11:11, pages 1265-1275.
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Articles from other publishers (36)

Tanya Chandra & Rohit Aggarwal. (2023) A Narrative Review of Acthar Gel for the Treatment of Myositis. Rheumatology and Therapy 10:3, pages 523-537.
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George Iliopoulos & Dimitrios Daoussis. (2023) FDA-APPROVED INDICATIONS OF ADRENOCORTICOTROPIC HORMONE (ACTH) AS A DRUG: DOES IT HAVE A PLACE IN DISEASE MANAGEMENT TODAY?. Central Asian Journal of Medical Hypotheses and Ethics 3:4, pages 220-231.
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Yael Sharon, Stephen D. Anesi, Christine E. Martinez, Andrew J. W. Huang, Charles Stephen Foster & David S. Chu. (2022) Repository Corticotropin Injection as an Alternative Treatment for Refractory Ocular Mucous Membrane Pemphigoid. Cornea 41:1, pages 45-51.
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Rohan Bir Singh, Shruti Sinha, Chhavi Saini, Elsayed Elbasiony, Sahil Thakur & Aniruddha Agarwal. (2020) Recent advances in the management of non-infectious posterior uveitis. International Ophthalmology 40:11, pages 3187-3207.
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Edward Chen, Hoyt Harris Reynolds & Lauren V. Graham. (2020) Ocular cicatricial pemphigoid treated with intramuscular corticotropin injections. JAAD Case Reports 6:5, pages 450-452.
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Stefanie Glaubitz, Rachel Zeng & Jens Schmidt. (2020) New insights into the treatment of myositis. Therapeutic Advances in Musculoskeletal Disease 12, pages 1759720X1988649.
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Chester V. Oddis & Rohit Aggarwal. 2020. Managing Myositis. Managing Myositis 275 283 .
Anjali Patwardhan & Charles H. Spencer. (2019) Biologics in refractory myositis: experience in juvenile vs. adult myositis; part II: emerging biologic and other therapies on the horizon. Pediatric Rheumatology 17:1.
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Yael Sharon & David S. Chu. (2019) Adrenocorticotropic hormone gel for patients with non-infectious uveitis. American Journal of Ophthalmology Case Reports 15, pages 100502.
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Muhammad Hassan, Samendra Karkhur, Jeong H. Bae, Muhammad S. Halim, Maria S. Ormaechea, Neil Onghanseng, Nam V. Nguyen, Rubbia Afridi, Yasir J. Sepah, Diana V. Do & Quan D. Nguyen. (2019) New therapies in development for the management of non‐infectious uveitis: A review. Clinical & Experimental Ophthalmology 47:3, pages 396-417.
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Rohit Aggarwal & Chester V Oddis. (2019) Response to: ’Elephant in the room' by Hartung et al . Annals of the Rheumatic Diseases 78:2, pages e12-e12.
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Simone Barsotti & Ingrid E. Lundberg. (2018) Current Treatment for Myositis. Current Treatment Options in Rheumatology 4:4, pages 299-315.
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Namita A. Goyal & Tahseen Mozaffar. (2018) Novel Therapeutic Options in Treatment of Idiopathic Inflammatory Myopathies. Current Treatment Options in Neurology 20:9.
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Yael Sharon & David S. Chu. (2018) Adrenocorticotropic hormone analogue as novel treatment regimen in ocular cicatricial pemphigoid. American Journal of Ophthalmology Case Reports 10, pages 264-267.
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Rohit Aggarwal, Galina Marder, Diane Carol Koontz, Preeya Nandkumar, Zengbiao Qi & Chester V Oddis. (2018) Efficacy and safety of adrenocorticotropic hormone gel in refractory dermatomyositis and polymyositis. Annals of the Rheumatic Diseases 77:5, pages 720-727.
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Chester V. Oddis & Rohit Aggarwal. (2018) Treatment in myositis. Nature Reviews Rheumatology 14:5, pages 279-289.
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Winnie W. Nelson, Michael J. Philbin, Jack R. Gallagher, Kylee Heap, Susan Carroll & George J. Wan. (2017) A Retrospective Medical Record Review of Utilization Patterns and Medical Resource Use Associated with Repository Corticotropin Injection among Patients with Rheumatologic Diseases in the United States. Rheumatology and Therapy 4:2, pages 465-474.
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Valérie Leclair & Ingrid E. Lundberg. (2017) Recent clinical trials in idiopathic inflammatory myopathies. Current Opinion in Rheumatology 29:6, pages 652-659.
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Lorenzo Cavagna, Sara Monti, Roberto Caporali, Mariele Gatto, Luca Iaccarino & Andrea Doria. (2017) How I treat idiopathic patients with inflammatory myopathies in the clinical practice. Autoimmunity Reviews 16:10, pages 999-1007.
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Gihyun Myung, Winnie W. Nelson & Maureen A. McMahon. (2017) Effects of Repository Corticotropin Injection on Medication Use in Patients With Rheumatologic Conditions: A Claims Data Study. Journal of Pharmacy Technology 33:4, pages 151-155.
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Michael Philbin, John Niewoehner & George J. Wan. (2017) Clinical and Economic Evaluation of Repository Corticotropin Injection: A Narrative Literature Review of Treatment Efficacy and Healthcare Resource Utilization for Seven Key Indications. Advances in Therapy 34:8, pages 1775-1790.
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Ilaria Pagnini, Antonio Vitale, Carlo Selmi, Rolando Cimaz & Luca Cantarini. (2015) Idiopathic Inflammatory Myopathies: an Update on Classification and Treatment with Special Focus on Juvenile Forms. Clinical Reviews in Allergy & Immunology 52:1, pages 34-44.
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Aniruddha Agarwal, Muhammad Hassan, Yasir J. Sepah, Diana V. Do & Quan Dong Nguyen. (2016) Subcutaneous repository corticotropin gel for non-infectious panuveitis: Reappraisal of an old pharmacologic agent. American Journal of Ophthalmology Case Reports 4, pages 78-82.
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C. V. Oddis. (2016) Update on the pharmacological treatment of adult myositis. Journal of Internal Medicine 280:1, pages 63-74.
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Ritu Lal, Stacie Bell, Rashida Challenger, Vakessa Hammock, Mary Nyberg, Dima Decker, Patrice M. Becker & David Young. (2015) Pharmacodynamics and tolerability of repository corticotropin injection in healthy human subjects: A comparison with intravenous methylprednisolone. The Journal of Clinical Pharmacology 56:2, pages 195-202.
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Aarat Patel, Georgia Seely & Rohit Aggarwal. (2016) Repository Corticotropin Injection for Treatment of Idiopathic Inflammatory Myopathies. Case Reports in Rheumatology 2016, pages 1-4.
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Ying Zhou, Elyse E. Lower, Huiping Li & Robert P. Baughman. (2016) Sarcoidosis patient with lupus pernio and infliximab-induced myositis: Response to Acthar gel. Respiratory Medicine Case Reports 17, pages 5-7.
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Merrilee Needham & Frank L. Mastaglia. (2015) Immunotherapies for Immune-Mediated Myopathies: A Current Perspective. Neurotherapeutics 13:1, pages 132-146.
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B. Volc-Platzer. (2015) Dermatomyositis – updateDermatomyositis—update. Der Hautarzt 66:8, pages 604-610.
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Jonathan Jones & Robert Wortmann. (2015) Idiopathic inflammatory myopathies—a review. Clinical Rheumatology 34:5, pages 839-844.
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Siamak Moghadam-Kia, Chester V Oddis & Rohit Aggarwal. (2014) Update on the treatment of myositis. International Journal of Clinical Rheumatology 9:5, pages 505-518.
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JJ Fiechtner & T Montroy. (2014) Treatment of moderately to severely active systemic lupus erythematosus with adrenocorticotropic hormone: a single-site, open-label trial. Lupus 23:9, pages 905-912.
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Lisa G. Rider, James D. Katz & Olcay Y. Jones. (2013) Developments in the Classification and Treatment of the Juvenile Idiopathic Inflammatory Myopathies. Rheumatic Disease Clinics of North America 39:4, pages 877-904.
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A.D. Keck & U.A. Walker. (2013) Therapie der MyositidenTherapy of myositis. Zeitschrift für Rheumatologie 72:3, pages 227-235.
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Rohit Aggarwal & Chester V. Oddis. (2012) Therapeutic advances in myositis. Current Opinion in Rheumatology 24:6, pages 635-641.
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Antonietta Citterio, Loredana La Mantia, Gabriele Ciucci, Livia Candelise, Fabio Brusaferri, Rune Midgard & Graziella Filippini. (2000) Corticosteroids or ACTH for acute exacerbations in multiple sclerosis. Cochrane Database of Systematic Reviews.
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