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Drug Design, Development and Therapy Volume 7, 2013 - Issue
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Original Research

Glyphosate and AMPA inhibit cancer cell growth through inhibiting intracellular glycine synthesis

Qingli Li1 Departments of Structural and Cellular Biology and Orthopaedic Surgery, Tulane Cancer Center and Louisiana Cancer Research Consortium, Tulane Center for Stem Cell Research and Regenerative Medicine, and Tulane Center for Aging, Tulane University Health Sciences Center, New Orleans, LA, USA;2 Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, People’s Republic of China
,
Mark J Lambrechts1 Departments of Structural and Cellular Biology and Orthopaedic Surgery, Tulane Cancer Center and Louisiana Cancer Research Consortium, Tulane Center for Stem Cell Research and Regenerative Medicine, and Tulane Center for Aging, Tulane University Health Sciences Center, New Orleans, LA, USA
,
Qiuyang Zhang1 Departments of Structural and Cellular Biology and Orthopaedic Surgery, Tulane Cancer Center and Louisiana Cancer Research Consortium, Tulane Center for Stem Cell Research and Regenerative Medicine, and Tulane Center for Aging, Tulane University Health Sciences Center, New Orleans, LA, USA
,
Sen Liu1 Departments of Structural and Cellular Biology and Orthopaedic Surgery, Tulane Cancer Center and Louisiana Cancer Research Consortium, Tulane Center for Stem Cell Research and Regenerative Medicine, and Tulane Center for Aging, Tulane University Health Sciences Center, New Orleans, LA, USA
,
Dongxia Ge1 Departments of Structural and Cellular Biology and Orthopaedic Surgery, Tulane Cancer Center and Louisiana Cancer Research Consortium, Tulane Center for Stem Cell Research and Regenerative Medicine, and Tulane Center for Aging, Tulane University Health Sciences Center, New Orleans, LA, USA
,
Rutie Yin2 Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, People’s Republic of China
,
Mingrong Xi2 Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, People’s Republic of China
&
Zongbing You1 Departments of Structural and Cellular Biology and Orthopaedic Surgery, Tulane Cancer Center and Louisiana Cancer Research Consortium, Tulane Center for Stem Cell Research and Regenerative Medicine, and Tulane Center for Aging, Tulane University Health Sciences Center, New Orleans, LA, USACorrespondence[email protected]
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Pages 635-643 | Published online: 24 Jul 2013

Citations (8)

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Read on this site (4)

Soyeon Jeon, Sang-Hyeop Lee, Jaechul Roh, Jang-Eok Kim & Heeyoun Bunch. (2020) Glyphosate influences cell proliferation in vitro. All Life 13:1, pages 54-65.
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Cindy Peillex & Martin Pelletier. (2020) The impact and toxicity of glyphosate and glyphosate-based herbicides on health and immunity. Journal of Immunotoxicology 17:1, pages 163-174.
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David Brusick, Marilyn Aardema, Larry Kier, David Kirkland & Gary Williams. (2016) Genotoxicity Expert Panel review: weight of evidence evaluation of the genotoxicity of glyphosate, glyphosate-based formulations, and aminomethylphosphonic acid. Critical Reviews in Toxicology 46:sup1, pages 56-74.
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Harry R. Hudson & Rosalind J. Lee. (2014) A Brief Review of the Anticancer Activity of α-Aminophosphonic Acid Derivatives and a Report on the in Vitro Activity of Some Dialkyl α-aryl- (or Heteroaryl)-α-(Diphenylmethylamino)Methanephosphonates. Phosphorus, Sulfur, and Silicon and the Related Elements 189:7-8, pages 1149-1155.
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Articles from other publishers (4)

Tomas Rivas-Garcia, Alejandro Espinosa-Calderón, Benjamin Hernández-Vázquez & Rita Schwentesius-Rindermann. (2022) Overview of Environmental and Health Effects Related to Glyphosate Usage. Sustainability 14:11, pages 6868.
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Bruno Sopko, Gracian Tejral, Guissepe Bitti, Marianna Abate, Martina Medvedikova, Marian Hajduch, Jan Chloupek, Jolana Fajmonova, Misa Skoric, Evzen Amler & Tomas Erban. (2021) Glyphosate Interaction with eEF1α1 Indicates Altered Protein Synthesis: Evidence for Reduced Spermatogenesis and Cytostatic Effect. ACS Omega 6:23, pages 14848-14857.
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András Székács & Béla Darvas. (2018) Re-registration Challenges of Glyphosate in the European Union. Frontiers in Environmental Science 6.
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Keshab Raj Parajuli, Qiuyang Zhang, Sen Liu & Zongbing You. (2016) Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model. Oncotarget 7:9, pages 10616-10626.
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