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Drug Design, Development and Therapy Volume 7, 2013 - Issue
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Original Research

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

Juan Antonio Marchal1 Biopathology and Regenerative Medicine Institute, Centre for Biomedical Research, Spain;2 Department of Human Anatomy and Embryology, Faculty of Medicine, University of Granada, Granada, Spain
,
Esther Carrasco1 Biopathology and Regenerative Medicine Institute, Centre for Biomedical Research, Spain
,
Alberto Ramirez1 Biopathology and Regenerative Medicine Institute, Centre for Biomedical Research, Spain;3 Department of Health Sciences, University of Jaén, Jaén, Spain
,
Gema Jiménez1 Biopathology and Regenerative Medicine Institute, Centre for Biomedical Research, Spain;2 Department of Human Anatomy and Embryology, Faculty of Medicine, University of Granada, Granada, Spain
,
Carmen Olmedo4 Experimental Surgery Research Unit, Virgen de las Nieves University Hospital, Granada, Spain
,
Macarena Peran1 Biopathology and Regenerative Medicine Institute, Centre for Biomedical Research, Spain;3 Department of Health Sciences, University of Jaén, Jaén, Spain
,
Ahmad Agil5 Department of Pharmacology and Neurosciences Institute, Faculty of Medicine, Spain
,
Ana Conejo-García6 Department of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada, Spain
,
Olga Cruz-López6 Department of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada, Spain
,
Joaquin María Campos6 Department of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada, SpainCorrespondence[email protected]
&
María Ángel García4 Experimental Surgery Research Unit, Virgen de las Nieves University Hospital, Granada, Spain;7 Department of Oncology, Virgen de las Nieves University Hospital, Granada, SpainCorrespondence[email protected]
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Pages 1301-1313 | Published online: 29 Oct 2013

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Olga Cruz-López, Matilde Ner, Francho Nerín-Fonz, Yaiza Jiménez-Martínez, David Araripe, Juan A. Marchal, Houria Boulaiz, Hugo Gutiérrez-de-Terán, Joaquín M. Campos & Ana Conejo-García. (2021) Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1551-1561.
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Articles from other publishers (3)

Konstantin A. Prosolov, Ekaterina G. Komarova, Ekaterina A. Kazantseva, Aleksandr S. Lozhkomoev, Sergei O. Kazantsev, Olga V. Bakina, Marina V. Mishina, Anastasia P. Zima, Sergei V. Krivoshchekov, Igor A. Khlusov & Yurii P. Sharkeev. (2022) UMAOH Calcium Phosphate Coatings Designed for Drug Delivery: Vancomycin, 5-Fluorouracil, Interferon α-2b Case. Materials 15:13, pages 4643.
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Robin Smyth & Jim Sun. (2021) Protein Kinase R in Bacterial Infections: Friend or Foe?. Frontiers in Immunology 12.
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Alberto Ramírez, Houria Boulaiz, Cynthia Morata-Tarifa, Macarena Perán, Gema Jiménez, Manuel Picon-Ruiz, Ahmad Agil, Olga Cruz-López, Ana Conejo-García, Joaquín M. Campos, Ana Sánchez, María A. García & Juan A. Marchal. (2014) HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib. Oncotarget 5:11, pages 3590-3606.
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