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Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date

José Fernando Vilela-MartinInternal Medicine Department, São José do Rio Preto State Medical School (FAMERP), São José do Rio Preto, BrazilCorrespondence[email protected]

Pages 1627-1639 | Published online: 09 May 2016

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Stavroula A. Zisopoulou, Thanos Andreou, Theocharis V. KoftisJohn K. Gallos & Christos I. Stathakis. (2023) Hetero-Diels–Alder Addition of Ethyl 2-Nitrosoacrylate to (Z)-Prop-1-enyl Ethers. Stereoselective Synthesis of a Precursor to Sacubitril. Synthesis 55:10, pages 1507-1516.
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Andrey I. Danilov, Andrey V. Evseev, Marina A. Evseeva, Olga V. Pavluchenkova & Vladimir A. Pereverzev. (2023) Sacubitril/valsartan as a component of therapy for chronic heart failure. Reviews on Clinical Pharmacology and Drug Therapy 20:4, pages 407-413.
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Naina Mohamed Pakkir Maideen, Rajkapoor Balasubramanian, Sudha Muthusamy & Venkateswaramurthy Nallasamy. (2022) An Overview of Clinically Imperative and Pharmacodynamically Significant Drug Interactions of Renin-Angiotensin-Aldosterone System (RAAS) Blockers. Current Cardiology Reviews 18:6.
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Nor Hidayah Mustafa, Juriyati Jalil, Satirah Zainalabidin, Mohammed S.M. Saleh, Ahmad Yusof Asmadi & Yusof Kamisah. (2022) Molecular mechanisms of sacubitril/valsartan in cardiac remodeling. Frontiers in Pharmacology 13.
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Carlos Daniel Varela-Chinchilla, Daniela Edith Sánchez-Mejía & Plinio A. Trinidad-Calderón. (2022) Congenital Heart Disease: The State-of-the-Art on Its Pharmacological Therapeutics. Journal of Cardiovascular Development and Disease 9:7, pages 201.
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Amy Hyein Kim, Jung Eun Jang & Jin Han. (2022) Current status on the therapeutic strategies for heart failure and diabetic cardiomyopathy. Biomedicine & Pharmacotherapy 145, pages 112463.
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Bahia Abbas Moussa, Hanaa M.A. Hashem, Marianne Alphonse Mahrouse & Sally Tarek Mahmoud. (2021) Synchronized determination of the novel heart failure combination therapy containing sacubitril calcium and valsartan by a validated spectrofluorimetric method. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 253, pages 119613.
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V. S. Nikiforov. (2020) Combined drug sacubitril/valsartan -a new era of treatment of chronic heart failure. Meditsinskiy sovet = Medical Council:14, pages 34-39.
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Katharina Hiebler, Carina Dertnig, Sebastian Soritz, Manuel C. Maier, Theresa R. Hörmann, Bianca Grabner & Heidrun Gruber-Woelfler. (2019) Development of a multistep reaction cascade for the synthesis of a sacubitril precursor in continuous flow. Journal of Flow Chemistry 10:1, pages 259-270.
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Katharina Hiebler, Sebastian Soritz, Kristian Gavric, Sam Birrer, Manuel C. Maier, Bianca Grabner & Heidrun Gruber-Woelfler. (2019) Multistep synthesis of a valsartan precursor in continuous flow. Journal of Flow Chemistry 10:1, pages 283-294.
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Surya Ayalasomayajula, Uwe Schuehly, Parasar Pal, Fabian Chen, Wei Zhou, Gangadhar Sunkara & Thomas H. Langenickel. (2018) Effect of the angiotensin receptor–neprilysin inhibitor sacubitril/valsartan on the pharmacokinetics and pharmacodynamics of a single dose of furosemide. British Journal of Clinical Pharmacology 84:5, pages 926-936.
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Michael Fralick, Jerry Avorn, Jessica M. Franklin, Abdurrahman Abdurrob & Aaron S. Kesselheim. (2018) Application and impact of run-in studies. Journal of General Internal Medicine 33:5, pages 759-763.
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Katharina Hiebler, Georg J Lichtenegger, Manuel C Maier, Eun Sung Park, Renie Gonzales-Groom, Bernard P Binks & Heidrun Gruber-Woelfler. (2018) Heterogeneous Pd catalysts as emulsifiers in Pickering emulsions for integrated multistep synthesis in flow chemistry. Beilstein Journal of Organic Chemistry 14, pages 648-658.
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Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud. (2017) Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics. Chromatographia 81:1, pages 139-156.
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Massimo Volpe, Caterina Santolamazza & Giuliano Tocci. (2016) Hypertension in Patients with Heart Failure with Reduced Ejection Fraction. Current Cardiology Reports 18:12.
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Huiqiong Xie, Miao Huang, Qiping Hu, Kejian Sun, Huayu Wu, Wei Shu, Xiaolong Li & Ling Fang. (2016) Agkihpin, a novel SVTLE from Gloydius halys Pallas, promotes platelet aggregation in vitro and inhibits thrombus formation in vivo in murine models of thrombosis. Toxicon 122, pages 78-88.
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Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date

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Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date

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