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Original Research

Efficacy and tolerability of oral oxycodone and oxycodone/naloxone combination in opioid-naïve cancer patients: a propensity analysis

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Pages 5863-5872 | Published online: 02 Nov 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Stefano De Santis, Cristina Borghesi, Serena Ricciardi, Daniele Giovannoni, Alberto Fulvi, Maria Rita Migliorino & Claudio Marcassa. (2016) Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain: an observational analysis. OncoTargets and Therapy 9, pages 4043-4052.
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Fabio Guerriero, Anna Roberto, Maria Teresa Greco, Carmelo Sgarlata, Marco Rollone & Oscar Corli. (2016) Long-term efficacy and safety of oxycodone–naloxone prolonged release in geriatric patients with moderate-to-severe chronic noncancer pain: a 52-week open-label extension phase study. Drug Design, Development and Therapy 10, pages 1515-1523.
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Articles from other publishers (24)

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Brian H Le, Ghauri Aggarwal, Carol Douglas, Michael Green, Amanda Nicoll & Sam Ahmedzai. (2021) Oxycodone/naloxone prolonged‐release tablets in patients with moderate‐to‐severe, chronic cancer pain: Challenges in the context of hepatic impairment. Asia-Pacific Journal of Clinical Oncology 18:1, pages 13-18.
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Man Soo Kim, In Jun Koh, Keun Young Choi, Sung Cheol Yang & Yong In. (2021) Efficacy of duloxetine compared with opioid for postoperative pain control following total knee arthroplasty. PLOS ONE 16:7, pages e0253641.
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Junya Sato, Rei Tanaka, Hiroshi Ishikawa, Tsutomu Suzuki & Michihiro Shino. (2019) A preliminary study of the effect of naldemedine tosylate on opioid-induced nausea and vomiting. Supportive Care in Cancer 28:3, pages 1083-1088.
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Oscar Corli, Vittorio Iorno, Lorenzo Legramandi, Eliana Rulli, Anna Roberto, Giuseppe Azzarello, Stefania Schiavon, Luigi Cavanna, Stefano De Santis, Claudio Cartoni, Pierangelo Di Marco, Mario Dauri, Rosario Mistretta, Roberto Bortolussi, Mario Clerico, Manuela Pacchioni, Carlo Crispino, Mirko Marabese, Nicole Corsi, Silvia Natoli, Gaspare Lipari, Marta Luzi, Giovanna Palumbo & Leonardo Trentin. (2019) Oral Prolonged‐Release Oxycodone‐Naloxone: Analgesic Response, Safety Profile, and Factors Influencing the Response in Patients With Advanced Cancer. Pain Practice 19:6, pages 633-643.
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Toshiyuki Kanemasa, Katsumi Koike, Tohko Arai, Hiroko Ono, Narumi Horita, Hiroki Chiba, Atsushi Nakamura, Yasuhide Morioka, Tsuyoshi Kihara & Minoru Hasegawa. (2019) Pharmacologic effects of naldemedine, a peripherally acting μ‐opioid receptor antagonist, in in vitro and in vivo models of opioid‐induced constipation. Neurogastroenterology & Motility 31:5, pages e13563.
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K. Rose, M. Steiner & W. Meißner. (2018) Therapie bei Tumorschmerz: Vergleich der S3-Leitlinie der AWMF zur Palliativmedizin und der WHO-LeitlinieTreatment of cancer pain: Comparison of the German AWMF S3 guideline on palliative care and the WHO recommendations. Der Onkologe 24:11, pages 861-871.
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M. Fallon, R. Giusti, F. Aielli, P. Hoskin, R. Rolke, M. Sharma & C.I. Ripamonti. (2018) Management of cancer pain in adult patients: ESMO Clinical Practice Guidelines. Annals of Oncology 29, pages iv166-iv191.
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P.J. Larkin, N.I. Cherny, D. La Carpia, M. Guglielmo, C. Ostgathe, F. Scotté & C.I. Ripamonti. (2018) Diagnosis, assessment and management of constipation in advanced cancer: ESMO Clinical Practice Guidelines. Annals of Oncology 29, pages iv111-iv125.
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Satoshi Inoue, Yoji Saito, Satoru Tsuneto, Etsuko Aruga, Hiroshi Takahashi & Mitsutoshi Uemori. (2018) A randomized, double-blind, non-inferiority study of hydromorphone hydrochloride immediate-release tablets versus oxycodone hydrochloride immediate-release powder for cancer pain: efficacy and safety in Japanese cancer patients. Japanese Journal of Clinical Oncology 48:6, pages 542-547.
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David J. Copenhaver, Nicolas B. Karvelas & Scott M. Fishman. (2017) Risk Management for Opioid Prescribing in the Treatment of Patients With Pain From Cancer or Terminal Illness: Inadvertent Oversight or Taboo?. Anesthesia & Analgesia 125:5, pages 1610-1615.
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Francesco Amato, Silvia Ceniti, Sergio Mameli, Giovanni M. Pisanu, Renato Vellucci, Vincenzo Palmieri, Leonardo Consoletti, Dorotea Magaldi, Paolo Notaro & Claudio Marcassa. (2017) High dosage of a fixed combination oxycodone/naloxone prolonged release: efficacy and tolerability in patients with chronic cancer pain. Supportive Care in Cancer 25:10, pages 3051-3058.
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Kaoru Toyama, Hidetoshi Furuie, Kana Kuroda & Hitoshi Ishizuka. (2017) Pharmacokinetic Bioequivalence Studies of an Extended-Release Oxycodone Hydrochloride Tablet in Healthy Japanese Subjects Under Fasting and Fed Conditions Without an Opioid Antagonist. Drugs in R&D 17:3, pages 363-370.
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Martin Hale, James Wild, Jyotsna Reddy, Tadaaki Yamada & Juan Camilo Arjona Ferreira. (2017) Naldemedine versus placebo for opioid-induced constipation (COMPOSE-1 and COMPOSE-2): two multicentre, phase 3, double-blind, randomised, parallel-group trials. The Lancet Gastroenterology & Hepatology 2:8, pages 555-564.
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Richard J. Bodnar. (2017) Endogenous Opiates and Behavior: 2015. Peptides 88, pages 126-188.
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Feifang He, Yilei Jiang & Li Li. (2016) The effect of naloxone treatment on opioid-induced side effects. Medicine 95:37, pages e4729.
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Gareth P. Jones & Shiva S. Tripathi. (2016) Oxycodone and Naloxone Combination: A 12-Week Follow-up in 20 Patients Shows Effective Analgesia Without Opioid-Induced Bowel Dysfunction. Pain and Therapy 5:1, pages 107-113.
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