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Review

Sitagliptin/metformin fixed-dose combination in type 2 diabetes mellitus: an evidence-based review of its place in therapy

Jennifer Hayes1 Department of Diabetes and Endocrinology, Morriston Hospital, ABM University NHS Trust

Rosie Anderson1 Department of Diabetes and Endocrinology, Morriston Hospital, ABM University NHS Trust

Jeffrey W Stephens1 Department of Diabetes and Endocrinology, Morriston Hospital, ABM University NHS Trust;2 Diabetes Research Group, Institute of Life Sciences, Swansea University, Swansea, UKCorrespondence[email protected]

Pages 2263-2270 | Published online: 19 Jul 2016

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E. V. Biryukova & D. V. Kileynikov. (2023) Metformin and sitagliptin fixed combination as the optimal choice in solving current problems in the type 2 diabetes mellitus treatment. Meditsinskiy sovet = Medical Council 17:9, pages 23-30.
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D. V. Kurkin, D. A. Bakulin, E. I. Morkovin, A. V. Strygin, Yu. V. Gorbunova, E. V. Volotova, I. E. Makarenko, V. B. Saparova, R. V. Drai & V. I. Petrov. (2023) Physiology, pharmacology and prospects for dipeptidilpeptidase-4 inhibitors use. Pharmacy & Pharmacology 11:1, pages 19-47.
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Min-Kyeong Hong, Youngji Han, Hae-Jin Park, Mi-Rae Shin, Seong-Soo Roh & Eun-Young Kwon. (2023) The Synergistic Action of Metformin and Glycyrrhiza uralensis Fischer Extract Alleviates Metabolic Disorders in Mice with Diet-Induced Obesity. International Journal of Molecular Sciences 24:2, pages 936.
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Syed Wasif Gillani, Syed Azhar Syed Sulaiman, Vineetha Menon, Nazeerullah Rahamathullah, Riham Mohamed Elshafie & Hassaan Anwer Rathore. (2022) Effect of different antidiabetic medications on atherosclerotic cardiovascular disease (ASCVD) risk score among patients with type-2 diabetes mellitus: A multicenter non-interventional observational study. PLOS ONE 17:6, pages e0270143.
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Abdel Naser Zaid, Yara Abu Zaaror, Aiman Kaddumi, Mashhour Ghanem, Nidal Jaradat, Tharaa Abu Salah, Sameera Siaj & Lana Omari. (2022) Stability of extemporaneously prepared sitagliptin phosphate solution. PLOS ONE 17:3, pages e0262068.
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Zhiguo Wang & Baofeng YangZhiguo Wang & Baofeng Yang. 2022. Polypharmacology. Polypharmacology 199 229 .

Amit Kaushal, Sandeep Arora, Neelam Sharma & Sukhbir Singh. (2021) Development of Bilayer Tablet Containing Saxagliptin Immediate Release and Metformin Sustained Release Using Quality by Design Approach. Current Drug Therapy 16:2, pages 184-203.
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Moon Hee Ko, Hyun Woo Cho & Jong Hyun Nho. (2020) Anti-hyperglycemic Effect of Bangpungtongseong-san on Type II Diabetes Animal Models. Korean Journal of Medicinal Crop Science 28:4, pages 287-297.
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Lamiaa M. Shawky, Ahmed A. Morsi, Eman El Bana & Safaa Masoud Hanafy. (2019) The Biological Impacts of Sitagliptin on the Pancreas of a Rat Model of Type 2 Diabetes Mellitus: Drug Interactions with Metformin. Biology 9:1, pages 6.
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Mei Wang, Sen Li, Fubaihui Wang, Jinhui Zou & Yanfeng Zhang. (2018) Aerobic exercise regulates blood lipid and insulin resistance via the toll‑like receptor 4‑mediated extracellular signal‑regulated kinases/AMP‑activated protein kinases signaling pathway. Molecular Medicine Reports.
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Claudia Guida, Sam Stephen, Romain Guitton & Reshma D. Ramracheya. (2017) The Role of PYY in Pancreatic Islet Physiology and Surgical Control of Diabetes. Trends in Endocrinology & Metabolism 28:8, pages 626-636.
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Zeynab Aliyari Serej, Abbas Ebrahimi Kalan, Ahmad Mehdipour & Hojjatollah Nozad Charoudeh. (2017) Regulation and roles of CD26/DPPIV in hematopoiesis and diseases. Biomedicine & Pharmacotherapy 91, pages 88-94.
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Sitagliptin/metformin fixed-dose combination in type 2 diabetes mellitus: an evidence-based review of its place in therapy

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Sitagliptin/metformin fixed-dose combination in type 2 diabetes mellitus: an evidence-based review of its place in therapy

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