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Drug Design, Development and Therapy Volume 10, 2016 - Issue
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Original Research

Solubility enhancement of simvastatin by arginine: thermodynamics, solute–solvent interactions, and spectral analysis

MMR Meor Mohd Affandi1 Laboratory of Fundamental Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor, Malaysia;2 DDH Core, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor Darul Ehsan, Malaysia
,
Minaketan Tripathy1 Laboratory of Fundamental Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor, Malaysia;3 Pharmaceutical and Life Sciences Core, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor Darul Ehsan, MalaysiaCorrespondence[email protected]
,
Syed Adnan Ali Shah3 Pharmaceutical and Life Sciences Core, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor Darul Ehsan, Malaysia;4 Atta-ur-Rahman Institute for Natural Products Discovery (AuRIns), Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor, Malaysia
&
ABA Majeed1 Laboratory of Fundamental Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor, Malaysia;3 Pharmaceutical and Life Sciences Core, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor Darul Ehsan, Malaysia
Pages 959-969 | Published online: 02 Mar 2016

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Gehan F Balata, Ahmad S Zidan, Mohamad AS Abourehab & Ebtessam A Essa. (2016) Rapid disintegrating tablets of simvastatin dispersions in polyoxyethylene–polypropylene block copolymer for maximized disintegration and dissolution. Drug Design, Development and Therapy 10, pages 3211-3223.
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Articles from other publishers (9)

Popat S. Kumbhar, Arehalli S. Manjappa, Rohit R. Shah, Sameer J. Nadaf & John I. Disouza. (2023) Nanostructured Lipid Carrier–Based Gel for Repurposing Simvastatin in Localized Treatment of Breast Cancer: Formulation Design, Development, and In Vitro and In Vivo Characterization. AAPS PharmSciTech 24:5.
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Anam Saleem, Naveed Akhtar, Muhammad Usman Minhas, Arshad Mahmood, Kifayat Ullah Khan & Orva Abdullah. (2022) Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement. Gels 8:3, pages 196.
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Heejun Park, Hye Jin Seo, Eun-Sol Ha, Seung-hyeon Hong, Jeong-Soo Kim, Min-Soo Kim & Sung-Joo Hwang. (2020) Preparation and characterization of glimepiride eutectic mixture with l-arginine for improvement of dissolution rate. International Journal of Pharmaceutics 581, pages 119288.
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N.F. Zolkiflee, M.M.R. Meor Mohd Affandi & A.B.A. Majeed. (2020) Thermodynamics and solute-solvent interactions of lovastatin in an aqueous arginine solution. European Journal of Pharmaceutical Sciences 141, pages 105111.
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Diksha Puri, Gopal Lal Khatik & Tamilvanan Shunmugaperumal. (2019) Studies on olive-and silicone-oils-based Janus macroemulsions containing ginger to manage primary dysmenorrheal pain. Materials Science and Engineering: C 100, pages 276-285.
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Harmanpreet Singh, Manish Kumar, Suksham Gupta, Thenrajan Raja Sekharan & Shunmugaperumal Tamilvanan. (2017) Influence of hydrophilic polymers addition into cinnarizine–β-cyclodextrin complexes on drug solubility, drug liberation behaviour and drug permeability. Polymer Bulletin 75:7, pages 2987-3009.
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M.M.R. Meor Mohd Affandi, Minaketan Tripathy & A.B.A. Majeed. (2017) Solubility enhancement of simvastatin and atorvastatin by arginine: A solvodynamics study. Journal of Molecular Liquids 241, pages 359-366.
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M.M.R. Meor Mohd Affandi, Minaketan Tripathy & A.B.A. Majeed. (2017) Solubility enhancement of simvastatin and atorvastatin by arginine: Contact angle determination, wettability and surface energy characteristics. Journal of Molecular Liquids 240, pages 340-344.
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M.M.R. Meor Mohd Affandi, Minaketan Tripathy & A.B.A. Majeed. (2016) Solubility enhancement of simvastatin and atorvastatin by arginine: Molecular dynamics and related solution chemistry using viscometric analysis. Journal of Molecular Liquids 223, pages 1093-1099.
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