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Drug Design, Development and Therapy Volume 10, 2016 - Issue
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Original Research

Randomized clinical trial: pharmacokinetics and safety of multimatrix mesalamine for treatment of pediatric ulcerative colitis

Carmen Cuffari1 Department of Pediatrics, Division of Pediatric Gastroenterology and Nutrition, The Johns Hopkins University School of Medicine, Baltimore, MD, USACorrespondence[email protected]
,
David Pierce2 Shire, Basingstoke, UK
,
Bartosz Korczowski3 Medical College, University of Rzeszów, Rzeszów, Poland
,
Krzysztof Fyderek4 University Children’s Hospital of Cracow, Cracow, Poland
,
Heather Van Heusen5 Shire, Wayne, PA, USA
,
Stuart Hossack6 Covance Clinical Research Unit Limited, Leeds, UK
,
Hong Wan5 Shire, Wayne, PA, USA
,
Alena YZ Edwards7 ICON Early Phase Services, Marlow, Buckinghamshire, UK
&
Patrick Martin5 Shire, Wayne, PA, USA
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Pages 593-607 | Published online: 04 Feb 2016

Citations (9)

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Asad Majeed Khan, Muhammad Hanif, Nadeem Irfan Bukhari, Rahat Shamim, Fatima Rasool, Sumaira Rasul & Sana Shafique. (2020) Artificial Neural Network (ANN) Approach to Predict an Optimized pH-Dependent Mesalamine Matrix Tablet. Drug Design, Development and Therapy 14, pages 2435-2448.
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Articles from other publishers (8)

Nicholas Michael Croft, Bartosz Korczowski, Jarosław Kierkuś, Beatriz Caballero & Manoj Kumar Thakur. (2023) Safety and efficacy of multimatrix mesalamine in paediatric patients with mild-to-moderate ulcerative colitis: a phase 3, randomised, double-blind study. eClinicalMedicine 65, pages 102232.
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Junrong Li, Fangmei Ling, Di Guo, Jinfang Zhao, Ling Cheng, Yidong Chen, Mingyang Xu & Liangru Zhu. (2022) The efficacy of mesalazine on nonspecific terminal ileal ulcers: A randomized controlled trial. Frontiers in Pharmacology 13.
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Yuichiro Ohtaki, Kan Uchiyama, Hirotaka Kamiya, Eri Moriizumi, Moe Yamada, Yuma Aoki, Toshimune Watanabe, Sachie Kiryu, Shizuka Suzuki, Yoshihiro Matsumoto, Zensho Ito, Toshifumi Ohkusa, Shigeo Koido & Masayuki Saruta. (2022) The insoluble excretion of multi-matrix system mesalazine preparations in patients with ulcerative colitis. BMC Gastroenterology 22:1.
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Ajit Sood, Vineet Ahuja, Vandana Midha, Saroj Kant Sinha, C. Ganesh Pai, Saurabh Kedia, Varun Mehta, Sawan Bopanna, Philip Abraham, Rupa Banerjee, Shobna Bhatia, Karmabir Chakravartty, Sunil Dadhich, Devendra Desai, Manisha Dwivedi, Bhabhadev Goswami, Kirandeep Kaur, Rajeev Khosla, Ajay Kumar, Ramit Mahajan, S. P. Misra, Kiran Peddi, Shivaram Prasad Singh & Arshdeep Singh. (2020) Colitis and Crohn’s Foundation (India) consensus statements on use of 5-aminosalicylic acid in inflammatory bowel disease. Intestinal Research 18:4, pages 355-378.
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Palika DattaKathleen Rewers-FelkinsRaja Reddy KallemTeresa BakerThomas W. Hale. (2019) Determination of Mesalamine levels in Human Milk as a Function of Dose. Breastfeeding Medicine 14:2, pages 98-101.
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Amy Hemperly, William J Sandborn & Niels Vande Casteele. (2018) Clinical Pharmacology in Adult and Pediatric Inflammatory Bowel Disease. Inflammatory Bowel Diseases 24:12, pages 2527-2542.
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Dan Turner, Frank M. Ruemmele, Esther Orlanski‐Meyer, Anne M. Griffiths, Javier Martin de Carpi, Jiri Bronsky, Gabor Veres, Marina Aloi, Caterina Strisciuglio, Christian P. Braegger, Amit Assa, Claudio Romano, Séamus Hussey, Michael Stanton, Mikko Pakarinen, Lissy de Ridder, Konstantinos Katsanos, Nick Croft, Victor Navas‐López, David C. Wilson, Sally Lawrence & Richard K. Russell. (2018) Management of Paediatric Ulcerative Colitis, Part 1. Journal of Pediatric Gastroenterology and Nutrition 67:2, pages 257-291.
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Alex Yu, Jason R. Baker, Ann F. Fioritto, Ying Wang, Ruijuan Luo, Siwei Li, Bo Wen, Michael Bly, Yasuhiro Tsume, Mark J. Koenigsknecht, Xinyuan Zhang, Robert Lionberger, Gordon L. Amidon, William L. Hasler & Duxin Sun. (2016) Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract . Molecular Pharmaceutics 14:2, pages 345-358.
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