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Drug Design, Development and Therapy Volume 10, 2016 - Issue
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Original Research

The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

Kuo-Hsuan Chang1 Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, Republic of China
,
I-Cheng Chen1 Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, Republic of China
,
Hsuan-Yuan Lin2 Department of Life Science, National Taiwan Normal University, Taipei, Taiwan, Republic of China
,
Hsuan-Chiang Chen2 Department of Life Science, National Taiwan Normal University, Taipei, Taiwan, Republic of China
,
Chih-Hsin Lin1 Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, Republic of China
,
Te-Hsien Lin2 Department of Life Science, National Taiwan Normal University, Taipei, Taiwan, Republic of China
,
Yu-Ting Weng1 Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, Republic of China
,
Chih-Ying Chao1 Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, Republic of China
,
Yih-Ru Wu1 Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, Republic of China
,
Jung-Yaw Lin2 Department of Life Science, National Taiwan Normal University, Taipei, Taiwan, Republic of China
,
Guey-Jen Lee-Chen2 Department of Life Science, National Taiwan Normal University, Taipei, Taiwan, Republic of ChinaCorrespondence[email protected]
&
Chiung-Mei Chen1 Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, Republic of ChinaCorrespondence[email protected]
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Pages 885-896 | Published online: 29 Feb 2016

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Rimaljot Singh, Navpreet Kaur, Neelima Dhingra & Tanzeer Kaur. (2023) Protein misfolding, ER stress and chaperones: an approach to develop chaperone-based therapeutics for Alzheimer’s disease. International Journal of Neuroscience 133:7, pages 714-734.
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Articles from other publishers (9)

Michael Bell & Hans Zempel. (2022) SH-SY5Y-derived neurons: a human neuronal model system for investigating TAU sorting and neuronal subtype-specific TAU vulnerability. Reviews in the Neurosciences 33:1, pages 1-15.
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Ya-Jen Chiu, Te-Hsien Lin, Chiung-Mei Chen, Chih-Hsin Lin, Yu-Shan Teng, Chung-Yin Lin, Ying-Chieh Sun, Hsiu Mei Hsieh-Li, Ming-Tsan Su, Guey-Jen Lee-Chen, Wenwei Lin & Kuo-Hsuan Chang. (2021) Novel Synthetic Coumarin-Chalcone Derivative (E)-3-(3-(4-(Dimethylamino)Phenyl)Acryloyl)-4-Hydroxy-2H-Chromen-2-One Activates CREB-Mediated Neuroprotection in Aβ and Tau Cell Models of Alzheimer’s Disease. Oxidative Medicine and Cellular Longevity 2021, pages 1-19.
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Xin Chen, Joshua Drew, Wren Berney & Wei Lei. (2021) Neuroprotective Natural Products for Alzheimer’s Disease. Cells 10:6, pages 1309.
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Yuan Ma, Man-wen Yang, Xin-wei Li, Jian-wei Yue, Jun-zong Chen, Mei-wen Yang, Xuan Huang, Lian-lian Zhu, Fen-fang Hong & Shu-long Yang. (2019) Therapeutic Effects of Natural Drugs on Alzheimer’s Disease. Frontiers in Pharmacology 10.
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I-Cheng Chen, Kuo-Hsuan Chang, Yi-Jing Chen, Yi-Chun Chen, Guey-Jen Lee-Chen & Chiung-Mei Chen. (2019) Pueraria lobata and Daidzein Reduce Cytotoxicity by Enhancing Ubiquitin-Proteasome System Function in SCA3-iPSC-Derived Neurons . Oxidative Medicine and Cellular Longevity 2019, pages 1-18.
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Sunil Kumar Dubey, Munnangi Siva Ram, Kowthavarapu Venkata Krishna, Ranendra Narayan Saha, Gautam Singhvi, Mukta Agrawal, Ajazuddin, Swarnlata Saraf, Shailendra Saraf & Amit Alexander. (2019) Recent Expansions on Cellular Models to Uncover the Scientific Barriers Towards Drug Development for Alzheimer’s Disease. Cellular and Molecular Neurobiology 39:2, pages 181-209.
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I-Cheng Chen, Te-Hsien Lin, Yu-Hsuan Hsieh, Chih-Ying Chao, Yih-Ru Wu, Kuo-Hsuan Chang, Ming-Chung Lee, Guey-Jen Lee-Chen & Chiung-Mei Chen. (2018) Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation. Oxidative Medicine and Cellular Longevity 2018, pages 1-16.
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Devesh Tewari, Adrian M. Stankiewicz, Andrei Mocan, Archana N. Sah, Nikolay T. Tzvetkov, Lukasz Huminiecki, Jarosław O. Horbańczuk & Atanas G. Atanasov. (2018) Ethnopharmacological Approaches for Dementia Therapy and Significance of Natural Products and Herbal Drugs. Frontiers in Aging Neuroscience 10.
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Yu Jin Kim, Hye-Sun Lim, Bu-Yeo Kim, Chang-Seob Seo & Soo-Jin Jeong. (2017) Quantitative Analysis and Biological Efficacies regarding the Neuroprotective and Antineuroinflammatory Actions of the Herbal Formula Jodeungsan in HT22 Hippocampal Cells and BV-2 Microglia. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-10.
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