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Original Research

The cytotoxicity study of praziquantel enantiomers

Qian SunDepartment of Pharmacy, Marine College, Shandong University, Weihai, People’s Republic of China

Ruifeng MaoDepartment of Pharmacy, Marine College, Shandong University, Weihai, People’s Republic of China

Dongling WangDepartment of Pharmacy, Marine College, Shandong University, Weihai, People’s Republic of China

Changyan HuDepartment of Pharmacy, Marine College, Shandong University, Weihai, People’s Republic of China

Yang ZhengDepartment of Pharmacy, Marine College, Shandong University, Weihai, People’s Republic of China

Dequn SunDepartment of Pharmacy, Marine College, Shandong University, Weihai, People’s Republic of ChinaCorrespondence[email protected]

Pages 2061-2068 | Published online: 24 Jun 2016

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Meiyu Zhang, Fangyu Zhang, Jingli Qiu, Xiaogui Shu, Tong Zhou, Sijia Liu, Yaxin Wang, Rong Liu, Xiantong Zheng & Limin He. (2023) Stereoselective Pharmacokinetics and Residue Depletion of Praziquantel and Its Metabolites, 4-Hydroxypraziquantel Enantiomers, in Swine. Journal of Agricultural and Food Chemistry 71:31, pages 12061-12069.
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Guo-Jing Yang & Xiao-Nong Zhou. (2023) A new formulation of praziquantel to achieve schistosomiasis elimination. The Lancet Infectious Diseases 23:7, pages 774-776.
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Jinyao Liu, Xiaofan Wu, Zhining Li, Zedu Huang & Fen-Er Chen. (2023) Engineered Monoamine Oxidase-Catalyzed Deracemization of Sterically Hindered Acylaminomethyl-tetrahydroisoquinoline: Asymmetric Synthesis of ( R )-(−)-Praziquantel and Its Analogues . ACS Sustainable Chemistry & Engineering 11:19, pages 7552-7559.
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Tayo A. Adekiya, Pradeep Kumar, Pierre P. D. Kondiah, Philemon Ubanako & Yahya E. Choonara. (2022) In Vivo Evaluation of Praziquantel-Loaded Solid Lipid Nanoparticles against S. mansoni Infection in Preclinical Murine Models. International Journal of Molecular Sciences 23:16, pages 9485.
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Oxana Zaparina, Akbota S Rakhmetova, Nataliya G Kolosova, Guofeng Cheng, Viatcheslav A Mordvinov & Maria Y Pakharukova. (2021) Antioxidants resveratrol and SkQ1 attenuate praziquantel adverse effects on the liver in Opisthorchis felineus infected hamsters. Acta Tropica 220, pages 105954.
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Viatcheslav A. Mordvinov, Denis V. Ponomarev, Yuri V. Pakharukov & Maria Y. Pakharukova. (2021) Anthelmintic Activity of Antioxidants: In Vitro Effects on the Liver Fluke Opisthorchis felineus. Pathogens 10:3, pages 284.
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Heinz Mehlhorn. 2021. Sino-African Cooperation for Schistosomiasis Control in Zanzibar. Sino-African Cooperation for Schistosomiasis Control in Zanzibar 13 41 .

Thibaud Reyser, Tung H. To, Chinedu Egwu, Lucie Paloque, Michel Nguyen, Alexandre Hamouy, Jean-Luc Stigliani, Christian Bijani, Jean-Michel Augereau, Jean-Patrick Joly, Julien Portela, Jeffrey Havot, Sylvain R. A. Marque, Jérôme Boissier, Anne Robert, Françoise Benoit-Vical & Gérard Audran. (2020) Alkoxyamines Designed as Potential Drugs against Plasmodium and Schistosoma Parasites. Molecules 25:17, pages 3838.
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Meiyu Zhang, Jingli Qiu, Xiaogui Shu, Xiaoling Tang, Xuefang Sha, Li Wu, Jun Fan, Dongping Zeng, Rujian He, Weiguang Zhang, Zhenling Zeng, Rong Liu & Limin He. (2020) Pharmacokinetics, Activity, and Residue Elimination of R - and S -Diclazuril in Broiler Chickens . Journal of Agricultural and Food Chemistry 68:33, pages 8987-8995.
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Nyasha Nicole Kapungu, Xueqing Li, Charles Nhachi, Collen Masimirembwa & Roslyn Stella Thelingwani. (2020) In vitro and in vivo human metabolism and pharmacokinetics of S‐ and R‐praziquantel. Pharmacology Research & Perspectives 8:4.
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Tienne Aparecida Nascimento, Camilla Fonseca Silva, Hanna Leijoto de Oliveira, Ricky Cássio Santos da Silva, Clebio Soares Nascimento & Keyller Bastos Borges. (2020) Magnetic molecularly imprinted conducting polymer for determination of praziquantel enantiomers in milk. The Analyst 145:12, pages 4245-4253.
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D. F. Avgustinovich, M. A. Tsyganov, M. Y. Pakharukova, E. N. Chulakov, A. V. Dushkin, V. P. Krasnov & V. A. Mordvinov. (2019) Effectiveness of Repeated Administration of Praziquantel with Disodium Glycyrrhizinate and Two Enantiomers of Praziquantel on Opisthorchis felineus (Rivolta, 1884). Acta Parasitologica 65:1, pages 156-164.
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Jéssika de Oliveira Viana, Marcus T. Scotti & Luciana Scotti. 2020. Schistosoma mansoni. Schistosoma mansoni 9 26 .

Karolina Słoczyńska, Paulina Koczurkiewicz, Kamil Piska, Beata Powroźnik, Katarzyna Wójcik-Pszczoła, Katarzyna Klaś, Magdalena Wyszkowska-Kolatko & Elżbieta Pękala. (2019) Similar Safety Profile of the Enantiomeric N-Aminoalkyl Derivatives of Trans-2-Aminocyclohexan-1-ol Demonstrating Anticonvulsant Activity. Molecules 24:13, pages 2505.
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Damira Avgustinovich, Mikhail Tsyganov, Galina Vishnivetskaya, Anna Kovner, Irina Sorokina, Irina Orlovskaya, Lyudmila Toporkova, Elena Goiman, Tatiana Tolstikova, Alexander Dushkin, Nikolay Lyakhov & Viatcheslav Mordvinov. (2019) Effects of supramolecular complexation of praziquantel with disodium glycyrrhizinate on the liver fluke Opisthorchis felineus: An in vitro and in vivo study. Acta Tropica 194, pages 1-12.
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Carine Santana Ferreira Marques, Polyana Rezende, Luciana N. Andrade, Tiago M.F. Mendes, Silmara M. Allegretti, Cristiane Bani, Marco Vinicius Chaud, Mônica Batista de Almeida, Eliana B. Souto, Luiz Pereira da Costa & Patrícia Severino. (2018) Solid dispersion of praziquantel enhanced solubility and improve the efficacy of the schistosomiasis treatment. Journal of Drug Delivery Science and Technology 45, pages 124-134.
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Sung-Tae Hong. (2018) Albendazole and Praziquantel: Review and Safety Monitoring in Korea. Infection & Chemotherapy 50:1, pages 1.
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Bin Jiang, Xiao-Nong Zhou, Hao-Bing Zhang, Yi Tao, Le-Le Huo & Ni Liu. (2017) Slow-release praziquantel for dogs: presentation of a new formulation for echinococcosis control. Infectious Diseases of Poverty 6:1.
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Zoltán‐István Szabó, Réka Gál, Levente Szőcs, Róbert Ludmerczki, Daniela‐Lucia Muntean, Béla Noszál & Gergő Tóth. (2017) Validated capillary electrophoretic method for the enantiomeric quality control of R ‐praziquantel . ELECTROPHORESIS 38:15, pages 1886-1894.
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