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Drug Design, Development and Therapy Volume 10, 2016 - Issue
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Review

The arsenal of pathogens and antivirulence therapeutic strategies for disarming them

John R Brannon1 Division of Molecular Pathogenesis, Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA
&
Maria Hadjifrangiskou1 Division of Molecular Pathogenesis, Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA;2 Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, TN, USACorrespondence[email protected]
Pages 1795-1806 | Published online: 27 May 2016

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Héctor Quezada, Mariano Martínez-Vázquez, Esaú López-Jácome, Bertha González-Pedrajo, Ángel Andrade, Ana María Fernández-Presas, Arturo Tovar-García & Rodolfo García-Contreras. (2020) Repurposed anti-cancer drugs: the future for anti-infective therapy?. Expert Review of Anti-infective Therapy 18:7, pages 609-612.
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Paula Blanco, Fernando Sanz-García, Sara Hernando-Amado, José Luis Martínez & Manuel Alcalde-Rico. (2018) The development of efflux pump inhibitors to treat Gram-negative infections. Expert Opinion on Drug Discovery 13:10, pages 919-931.
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Pantu Kumar Roy, Sung-Hee Park, Min Gyu Song & Shin Young Park. (2022) Antimicrobial Efficacy of Quercetin against Vibrio parahaemolyticus Biofilm on Food Surfaces and Downregulation of Virulence Genes. Polymers 14:18, pages 3847.
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Ulrik Engelsöy, Maria A. Svensson & Isak Demirel. (2021) Estradiol Alters the Virulence Traits of Uropathogenic Escherichia coli. Frontiers in Microbiology 12.
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Debadarshee Das Mohapatra, Smaranika Pattnaik & Sruti Panda. (2021) In Vitro Detected hly II Cytotoxin in a Strain of Staphylococcus aureus (BM S-2) and Plant-Derived Aromatic Components: a Molecular Docking Study. Applied Biochemistry and Biotechnology 193:6, pages 1639-1653.
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Miguel R. Lugo & Allan R. Merrill. (2020) Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins. Toxins 13:1, pages 16.
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Phylicia A. Aaron, Kiem Vu & Angie Gelli. (2020) An Antivirulence Approach for Preventing Cryptococcus neoformans from Crossing the Blood-Brain Barrier via Novel Natural Product Inhibitors of a Fungal Metalloprotease. mBio 11:4.
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Fernando Sanz-García, Carolina Alvarez-Ortega, Jorge Olivares-Pacheco, Paula Blanco, José Luis Martínez & Sara Hernando-Amado. (2019) Analysis of the Pseudomonas aeruginosa Aminoglycoside Differential Resistomes Allows Defining Genes Simultaneously Involved in Intrinsic Antibiotic Resistance and Virulence . Antimicrobial Agents and Chemotherapy 63:5.
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Francesca D'Angelo, Valerio Baldelli, Nigel Halliday, Paolo Pantalone, Fabio Polticelli, Ersilia Fiscarelli, Paul Williams, Paolo Visca, Livia Leoni & Giordano Rampioni. (2018) Identification of FDA-Approved Drugs as Antivirulence Agents Targeting the pqs Quorum-Sensing System of Pseudomonas aeruginosa . Antimicrobial Agents and Chemotherapy 62:11.
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Ronald Domalaon, Temilolu Idowu, George G. Zhanel & Frank Schweizer. (2018) Antibiotic Hybrids: the Next Generation of Agents and Adjuvants against Gram-Negative Pathogens?. Clinical Microbiology Reviews 31:2.
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