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Drug Design, Development and Therapy Volume 10, 2016 - Issue
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Review

Spotlight on sirukumab for the treatment of rheumatoid arthritis: the evidence to date

Pietro Enea Lazzerini1 Department of Medical Sciences, Surgery and Neurosciences, University of SienaCorrespondence[email protected]
,
Pier Leopoldo Capecchi1 Department of Medical Sciences, Surgery and Neurosciences, University of Siena
,
Giacomo Maria Guidelli1 Department of Medical Sciences, Surgery and Neurosciences, University of Siena
,
Enrico Selvi1 Department of Medical Sciences, Surgery and Neurosciences, University of Siena
,
Maurizio Acampa2 Stroke Unit, University Hospital of Siena, Siena, Italy
&
Franco Laghi-Pasini1 Department of Medical Sciences, Surgery and Neurosciences, University of Siena
Pages 3083-3098 | Published online: 26 Sep 2016

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Xin Zhao, Chenhao Zhang, Yi An, Zixuan Zhang, Jiahe Zhao, Xinwen Zhang, Yue Yang & Wei Cao. (2023) Research on Liver Damage Caused by the Treatment of Rheumatoid Arthritis with Novel Biological Agents or Targeted Agents. Journal of Inflammation Research 16, pages 443-452.
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Francesca Bartoli, Sangmee Bae, Laura Cometi, Marco Matucci Cerinic & Daniel E Furst. (2018) Sirukumab for the treatment of rheumatoid arthritis: update on sirukumab, 2018. Expert Review of Clinical Immunology 14:7, pages 539-547.
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Articles from other publishers (15)

Ali Berkant Avci, Eugen Feist & Gerd R. Burmester. (2023) Targeting IL-6 or IL-6 Receptor in Rheumatoid Arthritis: What Have We Learned?. BioDrugs.
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Susmita Srivastava & Mahaboobkhan Rasool. (2022) Underpinning IL-6 biology and emphasizing selective JAK blockade as the potential alternate therapeutic intervention for rheumatoid arthritis. Life Sciences 298, pages 120516.
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Pietro Enea Lazzerini, Riccardo Accioli, Maurizio Acampa, Wen-Hui Zhang, Decoroso Verrengia, Alessandra Cartocci, Maria Romana Bacarelli, Xiaofeng Xin, Viola Salvini, Ke-Su Chen, Fabio Salvadori, Antonio D’errico, Stefania Bisogno, Gabriele Cevenini, Tommaso Marzotti, Matteo Capecchi, Franco Laghi-Pasini, Long Chen, Pier Leopoldo Capecchi & Mohamed Boutjdir. (2022) Interleukin-6 Elevation Is a Key Pathogenic Factor Underlying COVID-19-Associated Heart Rate-Corrected QT Interval Prolongation. Frontiers in Cardiovascular Medicine 9.
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Pietro Enea Lazzerini, Franco Laghi-Pasini, Pier Leopoldo Capecchi & Mohamed Boutjdir. 2022. Torsades de Pointes. Torsades de Pointes 113 156 .
Shmuel Tiosano, Yarden Yavne, Abdulla Watad, Pnina Langevitz, Merav Lidar, Joy Feld, Moshe Tishler, Suhail Aamar, Ori Elkayam, Alexandra Balbir‐Gurman, Yair Molad, Sharon Ehrlich, Mahmoud Abu‐Shakra, Daniela Amital & Howard Amital. (2020) The impact of tocilizumab on anxiety and depression in patients with rheumatoid arthritis. European Journal of Clinical Investigation 50:9.
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Federico Biscetti, Maria Anna Nicolazzi, Andrea Flex & Raffaele Landolfi. (2019) Internists feel the rhythm. Internal and Emergency Medicine 15:2, pages 183-185.
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Amélie Leurs, David Launay, Louis Terriou, Pierre-Yves Hatron, Pierre Quartier & Eric Hachulla. (2019) Remission of Refractory Systemic-Onset Juvenile Idiopathic Arthritis After Treatment With Siltuximab. JCR: Journal of Clinical Rheumatology 25:4, pages e40-e42.
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Ali Berkant Avci, Eugen Feist & Gerd Rüdiger Burmester. (2018) Targeting IL-6 or IL-6 Receptor in Rheumatoid Arthritis: What’s the Difference?. BioDrugs 32:6, pages 531-546.
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Ernest H S Choy & Leonard H Calabrese. (2018) Neuroendocrine and neurophysiological effects of interleukin 6 in rheumatoid arthritis. Rheumatology 57:11, pages 1885-1895.
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Aprajita Jagpal & Jeffrey R. Curtis. (2018) Gastrointestinal Perforations with Biologics in Patients with Rheumatoid Arthritis: Implications for Clinicians. Drug Safety 41:6, pages 545-553.
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N. Basu, M. Karabayas & C. Pusey. (2018) Prognosis and future developments in vasculitis. Best Practice & Research Clinical Rheumatology 32:1, pages 148-165.
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Pietro Enea Lazzerini, Franco Laghi-Pasini, Iacopo Bertolozzi, Gabriella Morozzi, Sauro Lorenzini, Antonella Simpatico, Enrico Selvi, Maria Romana Bacarelli, Francesco Finizola, Francesca Vanni, Deana Lazaro, Ademuyiwa Aromolaran, Nabil El Sherif, Mohamed Boutjdir & Pier Leopoldo Capecchi. (2017) Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes. Heart 103:22, pages 1821-1829.
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Taher E. Taher, Jonas Bystrom, Voon H. Ong, David A. Isenberg, Yves Renaudineau, David J. Abraham & Rizgar A. Mageed. (2017) Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity. Clinical Reviews in Allergy & Immunology 53:2, pages 237-264.
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Daniela Gentile, Pietro E. Lazzerini, Alessandra Gamberucci, Mariarita Natale, Enrico Selvi, Francesca Vanni, Alessandra Alì, Paolo Taddeucci, Silvia Del-Ry, Manuela Cabiati, Veronica Della-Latta, David J. Abraham, Maria A. Morales, Rosella Fulceri, Franco Laghi-Pasini & Pier L. Capecchi. (2017) Searching Novel Therapeutic Targets for Scleroderma: P2X7-Receptor Is Up-regulated and Promotes a Fibrogenic Phenotype in Systemic Sclerosis Fibroblasts. Frontiers in Pharmacology 8.
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Mélissa Noack & Pierre Miossec. (2017) Selected cytokine pathways in rheumatoid arthritis. Seminars in Immunopathology 39:4, pages 365-383.
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